Description:
Myocardial infarction was local necrosis of heart tissue due to reduced oxygen supply because of the occlusion of coronary arteries. Fruits could reduce the risk of developing obesity and CVDs. Several studies have shown that apples had a strong cardioprotective effect. This study aimed to understand the cardioprotective activity of two variants of apples, e.g., Fuji and Malang, on isoproterenol-induced male Wistar rats. The cardioprotective activity test was carried out for 14 days, all testing group except negative control, was induced by isoproterenol. The results of testing cardioprotective activity showed that Fuji Apple juice and Apel Malang juice had the same capability to inhibit increasing cardiac biomarkers value (CK and CK-MB) with the highest inhibition was 79,56% and 73,08% for Fuji Apples, 69,18% and 43,04% for Apel Malang. The result of the cardiac histopathology examination showed that both Apples could prevent cardiac tissue damage. All juice Apple doses had the same cardioprotective activity

URL:
http://103.158.96.210:88/web_repository/uploads/41445-192000-1-PB.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
NENG F KURNIATI