Description:
Malaria is one of the health problems in the world and in Indonesia. This disease is caused by the protozoan parasite, the genus Plasmodium. Plasmodium falciparum is the most important parasitic disease with high morbidity and mortality in the world and tropical countries such as Indonesia in particular. This study aims to determine the activity of sampare leaf extract in inhibiting the growth of the FCR-3 strain of the P. falciparum parasite which causes malaria. Sampare leaves were extracted by maceration method using 70% ethanol. Extract the results extraction were tested against P. falciparum by in vitro method. 32,67% Yield extract resulted from the extraction process. Phytochemical screening shows the presence of alkaloid compounds, flavonoids, quinones, saponins, and tannins. The ethanol extract of sampare leaves had IC50 antimalarial activity of 0,125 µg/mL and was categorized very well.

URL:
http://103.158.96.210:88/web_repository/uploads/29477-170549-3-PB.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
KHAIRUDDIN KHAIRUDDIN