Repository Akfar Bumi Siliwangi



Preventive Effects of Spirulina platensis on Exercise-Induced Muscle Damage, Oxidative Stress and Inflammation in Taekwondo Athletes: A Randomized Cross-Over Trial



Description:
Background: Spirulina is an interesting nutritional supplement that has attracted a lot of attention. The aim of the present study was to examine the effect of spirulina supplementation on oxidative stress, inflammatory factors and plasma markers of exercise-induced muscle damage in male taekwondo athletes. Methods: A total of 18 trained taekwondo male athletes took part in a double-blind, placebocontrolled crossover study. Each subject received either spirulina (8 g/day) or placebo for 3 weeks. The study had two periods separated by a 14-day washout. Blood samples were taken after finishing a training checklist program (4 times in total). Results: There were no significant carryover effects; therefore, the two-week washout period was adequate. Compared to the placebo, a dose of 8 g / d of spirulina supplement over 21 days resulted in a significant decrease in plasma levels of lactate dehydrogenase (LDH), creatine kinase (CK) and interleukin 6 (IL6) and a significant increase in plasma levels of total antioxidant capacity (TAC), superoxide dismutase (SOD) and glutathione peroxidase (GPX) (p<0>0.05). Conclusion: Due to the improvement of antioxidant and anti-inflammatory conditions as well as appropriate protein content, spirulina supplementation can produce a preventive effect on exercise-induced muscle damage in taekwondo athletes.

URL:
http://103.158.96.210:88/web_repository/uploads/ps-28-589.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
Arvin Kashani