Description:
Metabolic syndrome is still a major problem in developing countries and it has an association with high blood
pressure, blood glucose, and lipid profle abnormalities, which can cause cardiovascular disease. This indicates
that it is important to provide adequate treatment, but patient compliance has effects on the outcome. Improving
patients’ compliance to treatment can provide a better control of the condition. Therefore, this study aimed to determine the association between medication compliance and the therapeutic outcome of metabolic syndrome. This
observational analytic study was conducted using a retrospective cohort design for one year of observation, namely
April 2020-March 2021. The infuence of patient compliance with therapy outcomes in terms of blood pressure,
blood glucose, and lipid profle was assessed using the medication possession ratio method. This study was carried out by examining patients’ medical records from the Bethesda Lempuyangwangi Hospital as parameters for
compliance, while the outcome parameters were assessed by experts. The data obtained were analyzed using
Anova (homogeneous data) or Kruskal-Wallis (not homogeneous data) to determine the differences in the compliance based on patients’ characteristics. The relationship of adherence to therapeutic outcomes was analyzed using
logistic bivariate. From 174 patients’ data that was observed, only 151 had a blood test. The average systolic blood
pressure, total cholesterol, triglyceride, and HbA1c levels were above the standard threshold. The three levels of
compliance had no signifcant relationship with blood pressure, HbA1c, and lipid profles (p>0.05). The adjusted
data for age and gender on adherence showed patients with low compliance, and they have a 2.08 times risk of
having high triglyceride levels compared to others (p<0.05). The results indicated the patients’ low compliance to
therapy, hence, health professionals must strengthen education to improve this condition.
URL:
http://103.158.96.210:88/web_repository/uploads/36619-155532-1-PB.pdf
Type:
Journal
Document:
Diploma III Farmasi
Date:
23-06-2024
Author:
Christianus H. Setiawan