Description:
Kaolin is one of the abundant clay minerals on earth which has been widely used in various industries. kaolin as a raw material in drugs manufacturing must comply several requirements in Pharmacopoeia such as not exceeding the heavy metal content limits. In this study, the analysis of heavy metal content (Pb, Sn, and As) was carried out on natural kaolin obtained from 3 different locations in Belitung regency. Testing of the brightness and particle size was also carried out to increase the value of kaolin as a pharmaceutical excipient. The highest recovery from kaolin was obtained in sample 3 which was 67.78%, while kaolin 1 and 2 which was 66.54, and 64.20%. Based on the results, the heavy metal testing it was known that kaolin 1, 2, and 3 have a Pb metal content of 55.200, 0.046, and 44.000 ppm, the metal of As obtained from kaolin 1, 2, 3 were 1.050, 78.300, and 0.761 ppm, respectively. Whereas the Sn mean metal was only found in kaolin 2 which was 0.003. White degree test results showed that kaolin 1, 2 and 3 have a high brightness, namely 92.94%, 93.00%, 91.16%. The results of particle size testing showed that all kaolin samples have size <2 ?m

URL:
http://103.158.96.210:88/web_repository/uploads/25675-92270-1-PB.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
NURUL I PASI