Repository Akfar Bumi Siliwangi



Efficacy of fractional flow reserve measurement in the assessment of stenotic lesions of coronary artery



Description:
Context: The decision to perform an intervention on a narrowed coronary artery depends on the ischemia caused by the stenosis. The indication for intervention usually applies to cases with ?70% stenosis of vascular diameter because of the risk of myocardial ischemia. Aims: To define the efficacy of fractional flow reserve (FFR) measurement in the evaluation of coronary artery stenosis. Methods: This prospective study was conducted on patients with intermediate coronary artery stenosis who underwent quantitative coronary angiography after coronary computed tomography angiography. Results: The study population consisted of 46 men and 26 women with a mean age of 66.0 ± 12.9 years. FFR was significantly correlated with the grade of angina pectoris (r = - 0.387; p<0 xss=removed xss=removed>55.62% diameter stenosis and MLD ? 1.08 mm. FFR ? 0.80 indicating intervention and FFR > 0.80 indicating medical therapy were observed in 56.9% and 43.1% of the cases, respectively. No major cardiac complications occurred during 12 months of follow-up in both groups. Conclusions: FFR measurements for intermediate stenosis of the coronary artery should be used to evaluate the possibility of myocardial ischaemia. If FFR is not available, a cut-off point of >55.62% diameter stenosis or MLD ? 1.08 mm can be used to predict the FFR results.

URL:
http://103.158.96.210:88/web_repository/uploads/jppres21.1177_10.1.128.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
Anh Binh Ho