Description:
Paku atai merah (Angiopteris ferox Copel) is a fern plant native from Kalimantan. The Dayak tribe uses the tuber as a mixture of traditional medicines and has the potential to be an antioxidant. The tuber of paku atai merah contains secondary metabolites, including alkaloids, steroids, flavonoids, tannins, and saponins. The study aimed to formulate an ethanol extract of the tuber of paku atai merah in capsule dosage form and evaluate the physical characteristics. Granules were prepared by varying the aerosol concentration, namely 5% (F1), 7% (F2), and 9% (F3). Granules were made using the wet granulation method, then the physical characteristics of the granules were evaluated. Granules that meet the requirements are then put into the capsule shell, followed by capsule evaluation. The results showed that all granule formulas met the physical characterization of granules such as organoleptic, moisture content, loss on drying, flow rate, angle of repose, true Bj, real Bj, compressed Bj, and porosity. However, in the capsule evaluation, only capsules containing granules of F2 and F3 met the physical characteristics of the capsule, such as weight uniformity, disintegration time, and hygroscopic tests

URL:
http://103.158.96.210:88/web_repository/uploads/46179-182873-2-PB.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
ANDI N AISYAH