Description:
Antibiotic resistance is a major global health problem and continues to increase, so there is a need for better evaluation and therapeutic advice for Urinary Tract Infection (UTI) patients. It had isolated E. coli from clinical isolates that were resistant to antibiotics of ?-lactam, the first generation of cephalosporin and fluoroquinolone. Characterization of bacterial sensitivity should be analyzed to other antibiotics with different mechanisms. Therefore, this study aims to analyze the antibiotic activity of fosfomycin, kanamycin, rifampicin, ceftriaxone, imipenem, and vancomycin against to resistant Escherichia coli clinical isolates of UTI. The sensitivity test in this study used the Kirby-Bauer disc diffusion method and data analysis using SPSS version 24. The results revealed the diameter of inhibition zone (mm) of antibiotics of fosfomycin, ceftriaxone, imipenem, kanamycin, rifampicin, and vancomycin respectively i.e. 38±1; 36.3±1.15; 35±1; 31.6±1,15; 28±1; and 26.3±0.17. Based on statistical analysis there were significant differences in the activity of fosfomycin, ceftriaxone, imipenem, kanamycin, rifampicin, and vancomycin.

URL:
http://103.158.96.210:88/web_repository/uploads/42856-163118-4-PB.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
TINA ROSTINAWATI