Repository Akfar Bumi Siliwangi



Biomolecular Mechanism of Herbal Medicine on Muscle Atrophy in Type 2 Diabetes Mellitus Rats: Systematic Review



Description:
Elevation in proinflammatory phenotype, oxidative damage, and advanced glycation end products are brought on by musculoskeletal atrophy and can result in both micro- and macrovascular problems. Sarcopenia may result from this loss of skeletal muscle mass, strength, and function. Herbal remedies have the capacity to build skeletal muscle mass and have been shown to be effective in treating a variety of human ailments. Herbal remedies have been shown to stimulate a number of different genes to stop muscular atrophy in chronic illnesses. The molecular processes by which herbal remedies prevent chronic disease-related muscle atrophy must be explained. In T2DM mice, the routes of inflammation, protein synthesis, apoptosis, autophagy, and glucose uptake are used to investigate the biomolecular mechanisms of each herbal remedy. The findings of the study indicate that 81 gene expressions may be triggered by herbal medicine in T2DM animals, thus avoiding muscular atrophy

URL:
http://103.158.96.210:88/web_repository/uploads/50895-204990-1-PB.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
ASEP KUSWANDI