Description:
Propionibacterium acnes is a bacterium that significantly contributes to the development and progression of acne—the phenomenon of bacterial proliferation. The alkaloid carpain present in papaya leaf extract exhibits antibacterial properties against Propionibacterium acnes, a bacterium associated with the development of acne. The facial wash is a cleansing product that removes bacteria and debris from the skin. This study aims to develop a facial wash gel formulation employing papaya leaf extract to treat and inhibit acne-causing bacteria. The formulation will involve the use of different concentrations of Carbopol 940 polymer, namely FI (1%), FII (1.5%), and FIII (2%), as a gelling agent. The research conducted falls under the category of experimental research. The assessment of facial wash gel formulations encompasses various parameters, such as organoleptic evaluation, homogeneity analysis, pH determination, viscosity measurement, spreadability assessment, and foaming capacity examination. The study's findings indicate that the formulation of the FII facial wash gel successfully fulfils all criteria for preparation evaluation. FI fails to satisfy the criteria for spreadability testing, while FIII needs to fulfil the homogeneity and viscosity testing requirements. The viscosity test was significantly affected by different amounts of Carbopol 940, which was used as a gelling agent. The pH, spreadability, and foamability tests were not significantly affected (p>0.05).

URL:
http://103.158.96.210:88/web_repository/uploads/6082-Article_Text-21257-1-10-20240701.pdf

Type:
Journal

Document:
Diploma III Farmasi

Date:
23-06-2024

Author:
Tubagus Akmal