Repository Akfar Bumi Siliwangi
Drug Utilization Study of Diuretics in Children with Hydrocephalus
Description:
Hydrocephalus is a condition characterized by a dynamic imbalance between formation and absorption of
cerebrospinal fluid that increases the size of intracranial space of the brain and, in some situations, an extension
of the outer space of the brain with or without increased ventricular size. This study aimed to examine the use of
diuretics and identify drug therapy problems in hospitalized children with hydrocephalus through the medical
record. The study design is observational retrospective with time-limited sampling based on data in medical
records at 2010-2013 periods, found 17 of 70 patients using diuretics therapy. There are three categories of
diuretic which are used were mannitol (70.6%), acetazolamide (23.5%), and a combination of mannitol and
acetazolamide (5.9%). Diuretics can be used for pre-op, post-op, and pre & post-op on all types of
hydrocephalus. Still, the specific use of diuretics may be caused by variations in comorbid diagnoses,
clinical data, and laboratory data for each patient. Adverse drug reactions are potentially dominant in DTP
analysis, and these are 7 of 17 patients. Monitoring of serum electrolytes such as sodium and potassium is
needed because it decreases are potential adverse drug reactions of diuretics.
Abstrak dibuat dalam bahasa Indonesia. Abstrak disusun dalam satu paragraf dengan jumlah kata tidak
lebih dari 250 kata. Isi mencakup latar belakang, tujuan, metode, hasil, dan simpulan
Type:
Procceding
Document:
Diploma III Farmasi
Date:
23-06-2024
Author:
Yen Yen Ari Indrawijaya