Repository Akfar Bumi Siliwangi



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08-09-2024
08-09-2024
23-06-2024
Does power distance in healthcare teams linked to patient satisfaction? A multilevel study of interprofessional care teams in a referral hospital in Indonesia

Susi Afrianti Rahayu (2024)

Background Interprofessional care teams collaborate to provide care to patients in hospitals to ensure their full recovery. To provide quality patient care, healthcare workers must have a comprehensive understanding of each other’s roles and co

23-06-2024
Formulasi dan Evaluasi Sediaan Spray gel Minyak Atsiri Niaouli (Melaleuca quinquenervia L.) dengan Karbopol 940 sebagai Pembentuk Gel

Calvin Tanjung (2024)

Acne vulgaris atau yang lebih dikenal dengan acne (jerawat) adalah kondisi inflamasi kronik pada kulit yang terjadi pada 9,4% populasi di dunia. Sekitar 85% diantara adalah kelompok usia remaja dan dewasa muda. Minyak atsiri niaouli dapat digun

23-06-2024
Demineralisasi Kalsium (Ca) dan Besi (Fe) pada Air Minum Soft Water Berteknologi Reverse Osmosis (RO)

Julyane (2024)

Kandungan kalsium dan besi yang berlebihan dalam air minum dapat menimbulkan masalah kesehatan diantaranya karies dan urolithiasis. Teknologi penyaringan air menggunakan membran Reverse Osmosis (RO) dinilai sebagai solusi untuk mengurangi zat a

23-06-2024
Evaluasi Kepatuhan Minum Obat Pasien Hipertensi Program Pengelolaan Penyakit Kronis (PROLANIS) di Salah Satu Klinik Kota Bandung

Yane Srie Herliany (2024)

Hipertensi termasuk ke dalam penyakit kronis yang seringkali disebut silent killer karena tidak adanya gejala dan tanpa disadari penderita mengalami komplikasi pada organ-organ vital. Salah satu sasaran PROLANIS yang diadakan oleh BPJS Kesehatan

23-06-2024
Evaluasi Kesesuaian Penyimpanan Obat High Alert di Salah Satu Rumah Sakit Kota Bogor dengan Standar Prosedur Operasional Rumah Sakit

Yusuf Supriadi (2024)

Obat high alert adalah obat yang harus diwaspadai karena sering menyebabkan terjadi kesalahan/kesalahan serius (sentinel event) dan Obat yang berisiko tinggi menyebabkan Reaksi Obat yang Tidak Diinginkan (ROTD). Penyimpanan obat high alert haru

23-06-2024
PENAMBATAN MOLEKUL SENYAWA AKTIF SIRIH (Piper betle L) TERHADAP RESEPTOR HSV-1 SEBAGAI KANDIDAT ANTI HERPES

Yunita Al Azzahra (2024)

Tanaman sirih secara tradisional telah digunakan untuk pengobatan beberapa penyakit seperti bau mulut, penyembuhan luka, anti radang, batuk pilek, gangguan pencernaan. Sebagian besar manfaat sirih untuk kesehatan berasal dari senyawa bioaktif f

23-06-2024
Formulasi Dan Evaluasi Sediaan Transdermal Patch Ekstrak Kulit Buah Apel Manalagi (Malus Sylvestris L. Mill) dengan Kombinasi Polimer Hidroksi Propil Metil Selulosa dan Etil Selulosa

Yusuf Supriadi (2024)

Kulit buah Apel Manalagi (Malus sylvestris L. Mill) memiliki kandungan senyawa fenolik dan flavonoid yang dapat digunakan sebagai antibakteri. Penelitian ini bertujuan untuk memperoleh sediaan transdermal patch dari ekstrak kulit buah Apel Mana

23-06-2024
Analisis Service Level Salah Satu Apotek Di Kota Bandung

Kamelia Agustini (2024)

Apotek merupakan fasilitas kesehatan yang memiliki tugas klinik dan non klinik. Tugas klinik dari apotek yaitu memberikan pelayanan penyerahan obat serta Bahan Habis Pakai (BHP) kepada pasien secara langsung baik melalui resep dari dokter maupu

23-06-2024
Formulasi Tablet Effervescent Ekstrak Bunga Kecombrang (Etlingera elatior (Jack)) dengan Variasi Kombinasi Asam Sitrat dan Asam Tartrat

YENNI PUSPITA TANJUNG (2024)

Bunga kecombrang (Etlingera elatior (Jack)) merupakan tumbuhan yang sudah banyak dikonsumsi oleh masyarakat sebagai penambah rasa pada makanan. selain itu bunga kecombrang diketahui memiliki manfaat sebagai antioksidan. Namun pemanfaatan bunga

23-06-2024
Formulasi Dan Evaluasi Sediaan Krim Anti-Aging Ekstrak Kulit Buah Mangga Harum Manis (Mangifera indica L.)

Tubagus Akmal (2024)

Di negera yang beriklim tropis seperti indonesia paparan sinar matahari tidak bisa dihindari terlebih seseorang yang bekerja di luar ruangan, tenaga kerja lapangan bisa terpapar sinar matahari sebanyak 10-70 %. Banyak masalah kulit yang dialami

23-06-2024
Pengaruh Waktu Penghangatan Nasi Putih dalam Rice Cooker Terhadap Kadar Vitamin B1 (Tiamin HCl)

Irma Rahmawati (2024)

Vitamin B1 (Tiamin HCl) memiliki peran penting dalam tubuh khususnya pada sistem saraf. Vitamin B1 terdapat pada berbagai jenis makanan, salah satunya adalah nasi. Penelitian ini bertujuan untuk mengetahui efek dari penggunaan Rice Cooker terhad

23-06-2024
POLYHERBAL FORMULATION OPTIMIZATION FROM CLITORIA TERNATEA, ROSMARINUS OFFICINALIS AND AQUILARIA MALACCENSIS USING SIMPLEX LATTICE DESIGN

Tubagus Akmal (2024)

Objective: This study aimed to optimize the composition of Clitoria ternatea flowers, Rosmarinus officinalis herbs, and Aquilaria malaccensis leaves as a polyherbal formulation. Methods: The polyherbal formulation (PHF) was systematically optimize

23-06-2024
Factors Affecting the Synthesis of Bovine Serum Albumin Nanoparticles Using the Desolvation Method

YENNI PUSPITA TANJUNG (2024)

Currently, protein-based nanoparticles are in high demand as drug delivery systems due to their exceptional qualities, including nontoxicity, nonantigenicity, and biodegradability. Other qualities include high nutritional value, abundance of renewa

23-06-2024
Pengaruh Senam Kaki terhadap Perubahan Kadar Gula Darah pada Lansia Penderita Diabetes Mellitus Tipe 2 di Puskesmas Cililin Kabupaten Bandung Barat

Sari Wahyuli Nalurita (2024)

Saat ini prevalensi penyakit Diabetes melitus tipe 2 semakin meningkat sehingga menjadi masalah kesehatan global. salah satu cara pencegahan yang dapat dilakukan untuk mengatasi Diabetes Melitus tipe 2 adalah dengan aktifitas olahraga rutin , h

23-06-2024
Knowledge, Perception, and Readiness of Indonesian Pharmacists for the Implementation of Telepharmacy-Based Pharmaceutical Services in Indonesia

Nasrul Wathoni (2024)

Background: Telepharmacy, a digital technology-driven approach, has emerged as a potential solution to address the challenges posed by this pandemic. Telepharmacy is a method used in pharmaceutical practice where a pharmacist utilizes telecommunica

23-06-2024
Application, Benefits, and Limitations of Telepharmacy for Patients with Diabetes in the Outpatient Setting

Ghina Nadhifah Iftinan (2024)

After the COVID-19 pandemic, telepharmacy has become increasingly widely used as an alternative to pharmaceutical care by remote pharmacists. Patients with diabetes mellitus are one of the patients who get benefit the most from telepharmacy practic

23-06-2024
Role of Pharmacists in the Interprofessional Care Team for Patients with Chronic Diseases

Susi Afrianti Rahayu (2024)

Chronic diseases are a major health problem and cause of death worldwide. Patients with chronic diseases should be managed by an interprofessional care team consisting of general practitioners, medical specialists, nurses, and pharmacists. However,

23-06-2024
?-LACTAMASES INHIBITOR-PRODUCING SOIL BACTERIA FOR AMPICILLINRESISTANT UROPATHOGENIC ESCHERICHIA COLI ISOLAT

SRI AGUNG FITRI KUSUMA (2024)

Objective: The goals of this investigation were to identify the species of the producers and ascertain the dose-dependent effect of extracellular products of Indonesian bacteria that generate ?-lactamases inhibitors. Methods: An agar diffusion tec

23-06-2024
?-Mangostin hydrogel film with chitosan alginate base for recurrent aphthous stomatitis (RAS) treatment: study protocol for double-blind randomized controlled trial

Cszahreyloren Vitamia (2024)

Background: Recurrent Aphthous Stomatitis (RAS) is a common ulcerative disease of the oral mucosa which is characterized by pain, and recurrent lesions in the oral cavity. This condition is quite painful, causing difficulty in eating, speaking and

23-06-2024
THE IMPACT OF DIVIDEND POLICY AND CAPITAL STRUCTURE ON FIRM VALUE IN AGRICULTURAL SECTOR

Senny Luckyardi (2024)

This study aims to determine the effect of Dividend Policy and Capital Structure on the Agricultural Sector's Company Value. The research method used in this study is the verification method with a quantitative approach. The case study was cond

23-06-2024
Natural and Synthetic Drugs Approached for the Treatment of Recurrent Aphthous Stomatitis Over the Last Decade

Cszahreyloren Vitamia (2024)

Recurrent aphthous stomatitis (RAS) refers to a sore and frequently recurring inflammation of the oral tissues, distinguished by the presence of small ulcers that cause significant discomfort and cannot be attributed to any underlying disease. Differ

23-06-2024
THE EFFECTIVENESS OF ELECTRONIC PURCHASE ON ORDERING NATIONAL HEALTH INSURANCE DRUGS AT THE WEST BANDUNG PHARMACY OF INDONESIA

Kamelia Agustini (2024)

This study aimed to determine the flow of use of the electronic drug purchase application, the level of suitability for ordering drugs, the constraints through the electronic drug purchase application, and its effectiveness on national health ins

23-06-2024
Patient Satisfaction Level of Chronic Illness National Health Insurance to Pharmaceutical Services

Kamelia Agustini (2024)

One of the quality services is by examining the degree of a client or patient satisfaction. Attempting to raise the standard of service is absolutely necessary as determined by the degree of patient satisfaction. This study aimed to assess how sati

23-06-2024
COMPARATIVE ANALYSIS OF CAFFEINE CONTENT IN COLD AND HOT BREWED ROBUSTA COFFEE USING HIGHPERFORMANCE LIQUID CHROMATOGRAPHY (HPLC)

Irma Rahmawati (2024)

Coffee is one of the most popular beverages globally, cherished for its unique taste, aroma, and the stimulating effects of its caffeine content. The proliferation of creative coffee shops has introduced various new methods for enjoying coffee,

23-06-2024
Analisis Kafein pada Kopi Arabika (Coffea arabica L.) Gununghalu Teknik Light Roasting, Medium Roasting, dan Dark Roasting

Irma Rahmawati (2024)

Kopi merupakan salah satu minuman yang paling banyak didistribusikan dan paling banyak diminum di dunia. Kopi arabika menguasai sekitar 70% pasar kopi dunia. Kopi dikenal sebagai minuman dengan kandungan kafein yang berkadar tinggi. Penelitian in

23-06-2024
Antibacterial Activity Test of Herbal and Non Herbal Bar Soap Against The Growth of Staphylococcus aureus ATCC29213

Susi Afrianti Rahayu (2024)

It is essential to maintain skin hygiene by removing dirt and bacteria, including Staphylococcus aureus. Soap is an effective method for maintaining clean skin, particularly antibacterial bar soap that incorporates triclosan (a non-herbal compone

23-06-2024
Local Hemostatic Activity of Several Varieties of Banana (Musa Paradisiaca) Pseudo-Stem Sap in Swiss Webster Mice

Cszahreyloren Vitamia (2024)

Skin injuries requiring local hemostatics for effective treatment.Indonesians have upheld the tradition of utilizing herbal, and one prominent example is the utilization of the banana tree (Musa paradisiaca) for its medicinal advantages. The purp

23-06-2024
Behavioral Technology Acceptance Model In Health Care Industry: Systematic Literature Review

Kamelia Agustini (2024)

Identify the problems of several Research Gaps, namely the lack of breadth and depth in the Technology Acceptance Model (TAM) variables with other variables that will be tested, as well as potential variables that contribute to improvements to th

23-06-2024
Comparison of Phenolic Content of Indonesian Bay Leaves (Syzygium polyanthum) Fresh Decoction And Herbal Tea

Irma Rahmawati (2024)

The Indonesian bay leaves (Syzygium polyanthum) are one of the traditional cooking spices used in several countries in Southeast Asia, and this spice gives a distinctive herbaceous aroma. Bay leaves are often used as a medicinal plant for generat

23-06-2024
IMPROVED SOLUBILITY OF CHOLECALCIFEROL AS BOVINE SERUM ALBUMIN (BSA) NANOPARTICLES

YENNI PUSPITA TANJUNG (2024)

Objective: This study aims to report the optimum formula for BSA nanoparticles cholecalciferol (BSA-NP cholecalciferol), which can increase the solubility of cholecalciferol. Methods: BSA cholecalciferol nanoparticles was prepared by desolvation m

23-06-2024
POTENTIAL ACTIVITY OF KAEMPFEROL AS ANTI-PARKINSON’S; MOLECULAR DOCKING AND PHARMACOPHORE MODELLING STUDY

UMIL MAHFUDIN (2024)

Objective: This study examined molecular docking and pharmacophore modeling to evaluate the potential antiparkinson activity of Kaempferol on various types and classes of receptors. Methods: The molecular docking was performed on various classes

23-06-2024
Antiviral Activity of Various Glycoside Compounds

Yunita Al Azzahra (2024)

Glycoside compounds consist of several groups of important compounds, such as flavonoids and alkaloids. Sometimes the glycosidic residues in glycoside compounds have an important role in their activity, but some can only increase their pharmacoki

23-06-2024
Formulation of Peel-off Gel Face Mask from Pandanus amaryllifolius (Roxb.) Leaves Extract

Tubagus Akmal (2024)

UV exposure is the most significant environmental risk factor that can be altered for skin cancer and many other skin conditions. An antioxidant is a compound that can protect the skin from sun radiation. Pandanus amaryllifolius is a plant that h

23-06-2024
Formulation of Blush on Cream from Roselle (Hibiscus sabdariffa L.) Flower Extract with Olive Oil as Emollients

Tubagus Akmal (2024)

Natural dyes have become more popular as a result of the harmful and carcinogenic effects of synthetic dyes. Anthocyanins are natural dyes that are widely used to replace synthetic dyes and can also act as antioxidants that can be found in rosell

23-06-2024
Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

YENNI PUSPITA TANJUNG (2024)

Basil (Ocimum basilicum) leaf essential oil contains terpenoid compounds that have antibacterial activity. This study aims to obtain hand cream preparations of basil essential oil, as well as to determine the effect of concentration variation of

23-06-2024
Formulation and Physical Evaluation of Edible Film Dosage from Ethanol Extract of Betel Leaves (Piper betle L) for Canker Sore Drugs

YENNI PUSPITA TANJUNG (2024)

Canker sore which in medical terms is called aphthous stomatitis is a wound in the mouth that can cause pain and discomfort. Piper betel leaf can be used for strengthening the teeth, cure canker sores, treat the bad breath and stop the gum from b

23-06-2024
Formulasi Dan Uji Stabilitas Fisik Sediaan Lip cream Ekstrak Ubi Jalar Ungu (Ipomoea batatas L.) Sebagai Pewarna Alami

Tubagus Akmal (2024)

Saat ini dipasaran masih terdapat kosmetik dekoratif yang menggunakan pewarna sintetik berbahaya. Sedangkan dalam kosmetik dekoratif warna merupakan bagian terpenting. Pigmen antosianin dalam ekstrak ubi jalar ungu (Ipomoea batatas L.) dapat di

23-06-2024
MORINGA LEAF INFUSION AND TEA: HOW ARE THEIR ANTIOXIDANT ACTIVITIES DIFFERENT?

Irma Rahmawati (2024)

The global pandemic of the COVID-19 virus has made people around the world aware of the importance of maintaining health. Various efforts have been made to prevent the transmission of the COVID-19 virus, one of which is increasing the body's re

23-06-2024
Facial Wash Gel Formulation from Papaya Leaf Extract (Carica papaya L.) With Carbopol 940 as Gelling Agent and Its Stability Study

Tubagus Akmal (2024)

Propionibacterium acnes is a bacterium that significantly contributes to the development and progression of acne—the phenomenon of bacterial proliferation. The alkaloid carpain present in papaya leaf extract exhibits antibacterial properties agai

23-06-2024
The Effect Of CRM on the Level of Pharmacy Consumer Satisfaction

Kamelia Agustini (2024)

This study focuses on CRM, namely drug information services, to determine the level of satisfaction of BPJS Health patients with CRM drug information services and to determine the effect of CRM on BPJS Health patient satisfaction levels at the

23-06-2024
ANALISIS PENGENDALIAN ALAT KESEHATAN NON ELEKTROMEDIK STERIL DAN NON STERIL MENGGUNAKAN METODE ABC DI SALAH SATU PENYALUR ALAT KESEHATAN KOTA BANDUNG

Yusuf Supriadi (2024)

The purpose of this research is to know the management of inventory into groups A, B and C based on the analysis of Activity Based Costing (ABC) method of use value and investment value in one of the distributors of medical devices in Bandung. Th

23-06-2024
WHAT IS BEHAVIORAL FINANCE??

Kamelia Agustini (2024)

Behavioral Finance adalah ilmu tentang perilaku, aspek psikologis bagi investor dalam mengambil keputusan investasi. Behavioral Finance menjelaskan penyimpangan/bias dengan terminologi psikologis. Selama empat puluh tahun terakhir, keuangan tra

23-06-2024
UJI AKTIVITAS ANALGESIK FRAKSI DAUN SENGGANI (Clidemia hirta [L] D.Don) PADA MENCIT PUTIH GALUR SWISS WEBSTER

Taufik Septiyan Hidayat (2024)

Rasa nyeri merupakan sensasi yang dapat mengganggu aktivitas dan menurunkan kualitas hidup penderitanya apabila tidak ditangani dan dibiarkan berkepanjangan. Senggani merupakan salah satu tanaman yang mengandung senyawa flavonoid dan steroid yang

23-06-2024
UJI AKTIVITAS ANTIINFLAMASI EKSTRAK BATANG AKAR KUNING (Arcangelisia flava (L.) Merr.) SECARA IN VITRO

Syumillah Saepudin (2024)

Inflamasi merupakan respon alami yang terjadi pada kerusakan jaringan yang disebabkan karena salah satunya stres oksidatif. Tanaman Akar kuning merupakan salah satu tanaman dari famili Menispermaceae yang mengandung senyawa bioaktif dengan bebera

23-06-2024
Covid-19 Drug Control Based on BPOM Informatorium with ABC Method at the Pharmacies of Bandung City

Kamelia Agustini (2024)

According to statistical data from JHU CSSE COVID-19 in June 2021, there was an increase in positive cases of Coronavirus and began to decline at the end of August 2021. The planning that has been made must be corrected using the ABC method because

23-06-2024
Effect of Light, Medium, and Dark Roasting on Antioxidant Activity of Gununghalu Arabica Coffee (Coffea arabica L.)

Irma Rahmawati (2024)

Coffee is one of the popular drinks for Indonesian people. Coffee consumption in Indonesia has increased very rapidly. The influence of lifestyle and the increasing number of cafes and coffee shops contribute to the increase in coffee consumers. On

23-06-2024
Potential Analysis of Drug Interactions in Schizophrenia Cases at One of the Bandung District Pharmacy, Indonesia

Yane Srie Herliany (2024)

Schizophrenia is a heterogeneous syndrome of thought disturbances, delusions, hallucinations, emotional disturbances, decreased cognitive function and disturbed psychosocial functions. Treatment of schizophrenia aims to prevent hospitalization, ens

23-06-2024
Citronella (Cymbopogon nardus (L.) Rendle) Leaves Infusion: Sedative Activity in Swiss-Webster Strain Male Mice

Cszahreyloren Vitamia (2024)

Insomnia is one of the sleep disorders and more severe symptoms can culminate in the onset of stress disorder. The high threat of being affected by COVID-19 causes insomnia, so drugs such as sedatives are required to treat this disorder. Research h

23-06-2024
Analgetic Effects of Kangkung (Ipomea reptans Poir) Extract on Swiss Webstesr Mice

Andi Ika Julianti Handayani (2024)

One of the efficacious plants as an empirical analytic is kangkung (Ipomea reptans Poir). The purpose of this study was to determine the analgesic effect of kangkung and determine the dose of kangkung extract compared to ibuprofen. The benefit of

23-06-2024
Formulation of Compressed Lozenges from Decaffeinated Arabica Green Coffee (Coffea arabica L.) Bean Extract as Immune Booster

Tubagus Akmal (2024)

Global public health issues include emerging and reemerging viruses. The most recent cause of COVID-19, the severe acute respiratory syndrome coronavirus (SARS-CoV-2). The main goal of current medical research is the creation of new, affordable,

23-06-2024
FORMULATION AND EVALUATION OF PEEL OFF GEL FACIAL MASK FROM ARABICA COFFEE FRUIT PEEL EXTRACT (COFFEA ARABICA L.)

YENNI PUSPITA TANJUNG (2024)

Objective: The aim of this study was to obtain a peel off gel facial mask preparation from Arabica coffee fruit peel extract that meets the requirements and to determine the antioxidant activity of Arabica coffee fruit peel extract and peel off gel

23-06-2024
INFLUENCE OF Momordica charantia (L.) ON THE PHARMACOKINETICS AND PHARMACODYNAMICS OF GLICLAZIDE IN ALLOXAN-INDUCED DIABETIC RATS MODEL

Tubagus Akmal (2024)

Diabetes mellitus is a metabolic disorder present in the top ten diseases that cause death. Diabetes treatment usually uses conventional drugs, such as gliclazide, which is the first choice in patients with type 2 diabetes mellitus who are intoler

23-06-2024
Phenolic content and antioxidant activity of Moringa oleifera leaf infusions and tea

Irma Rahmawati (2024)

The Moringa plant (Moringa oleifera L.) has been known for centuries as a multipurpose nutrient-dense plant and has medicinal properties, so it is called a miracle tree. One of its properties is that it functions as the main antiretroviral molecu

23-06-2024
Potensi Interaksi Obat Antihipertensi Pada Pasien Penyakit Ginjal Kronik di Rumah Sakit Khusus Ginjal Bandung

Yane Srie Herliany (2024)

Hipertensi merupakan salah satu faktor pemicu timbulnya penyakit ginjal kronik. Adanya kerusakan pembuluh darah dalam ginjal menyebabkan terjadinya penurunan kemampuan fungsi ginjal untuk menyaring (filtrasi) darah dengan baik. Penelitian ini be

23-06-2024
Uji Aktivitas Antibakteri Berbagai Merek Tisu Basah yang Beredar Sekitar Wilayah Sumedang terhadap Bakteri Staphylococcus aureus ATCC 29213

Susi Afrianti Rahayu (2024)

Tisu basah merupakan salah satu produk yang digunakan sebagai alternatif untuk menggantikan cuci tangan dengan menggunakan sabun dan air karena tisu basah dirasa lebih praktis untuk dibawa bepergian. Selain itu tisu basah juga dapat menghambat p

23-06-2024
Kajian Penggunaan Kombinasi TDF/3TC/EFV untuk Pasien HIV/AIDS Kota Bandung pada Salah Satu Rumah Sakit Swasta

Cszahreyloren Vitamia (2024)

Virus yang menyebabkan Acquired Immuno Deficiency Syndrome (AIDS) adalah virus Human Immunodeficiency Virus (HIV). AIDS sendiri merupakan suatu kumpulan gejala dengan kondisi berkurangnya kemampuan sistem kekebalan tubuh yang disebabkan oleh in

23-06-2024
Perbandingan Pelarut Terhadap Jumlah Rendemen Ekstrak Daun Singkong (Manihot utilissima Pohl) Menggunakan Metode Soxhletasi

Andi Ika Julianti Handayani (2024)

Tumbuhan daun singkong merupakan tumbuhan obat yang digunakan secara turun-temurun, salah satunya dapat mengobati rematik, asam urat, anemia, konstipasi, serta untuk meningkatkan daya tahan tubuh. Tujuan dari penelitian ini yaitu untuk mengetah

23-06-2024
Laporan Kasus: Epilepsi pada Wanita Muda

Noviyanty Indjar Gama (2024)

Epilepsi adalah kelainan kronis pada otak yang ditandai dengan kejang berulang akibat pelepasan muatan listrik yang berlebihan pada sekelompok sel saraf. Epilepsi menjadi salah satu penyebab morbiditas yang dapat menyerang semua umur. Penyakit in

23-06-2024
Skrining Fitokimia dan Uji Aktivitas Tabir Surya Ekstrak Etanol Daun Rambutan (Nephelium lappaceum L.)

Ayu Lestari (2024)

Rambutan (Nephelium lappaceum L.) merupakan tanaman tropis yang banyak terdapat di Indonesia yang dapat dimanfaatkan sebagai tabir surya untuk melindungi kulit dari radiasi sinar UV. Tujuan dari penelitian ini adalah untuk mengetahui kandungan se

23-06-2024
Skrining Fitokimia dan Uji Aktivitas Antibakteri Ekstrak Daun Cabai Rawit (Capsiccum frutescens L.) terhadap Staphylococcus epidermidis

Annisa Nismaul Husna (2024)

Daun cabai rawit (Capsiccum frutescens L.) merupakan tanaman yang memiliki banyak manfaat salah satunya di bidang kesehatan. Secara ilmiah daun cabai rawit berperan sebagai antioksidan, antibakteri dan dapat mencegah diabetes. Aktivitas tersebut

23-06-2024
Uji Aktivitas Antioksidan Berdasarkan Perbedaan Tingkat Kematangan Buah Alpukat (Persea americana Mill.) Menggunakan Metode DPPH

Sitti Mujahida Tahir (2024)

Buah alpukat (Persea americana Mill.) memiliki aktivitas sebagai antioksidan. Aktivitas ini sangat dipengaruhi oleh metabolit yang terkandung pada buah alpukat. Namun demikian pembentukan metabolit-metabolit aktif ini sangat dipengaruhi oleh ting

23-06-2024
Observasi Klinik Penggunaan Obat Sariawan pada Remaja

Sitti Mujahida Tahir (2024)

Sariawan merupakan penyakit pada mukosa mulut yang sering dialami oleh masyarakat. Terdapat berbagai pilihan dalam menyembuhkan sariawan seperti menggunakan obat sintetik yang mengandung antiseptik ataupun analgesik. Pada penyembuhan sariawan ini

23-06-2024
Evaluasi Penggunaan Obat pada Pasien Artritis Gout di Instalasi Rawat Jalan Rumah Sakit Pupuk Kaltim Bontang Periode 2022

Silvia Ningsih Manurung (2024)

Artritis gout adalah penyakit akibat deposisi kristal monosodium urat (MSU) di sendi, ginjal, dan jaringan ikat lainnya sebagai akibat dari hiperurisemia yang dapat menimbulkan nyeri, bengkak, gangguan gerak sendi, dan bahkan tophi. Tanpa pengoba

23-06-2024
Identifikasi Potentially Inappropriate Medication (PIM’s) Menggunakan Kriteria Beers dan STOPP pada Pasien Geriatri dengan Diagnosis Gastrointestinal Rawat Inap di RSUD Abdul Wahab Sjahranie Samarinda

Rahmayunitha Muriana (2024)

Kriteria Beers dan STOPP adalah kriteria yang digunakan untuk mengidentifikasi kemungkinan pengobatan yang tidak tepat termasuk obat yang harus dihindari dan digunakan pada pasien yang berusia lebih dari 65 tahun. Kedua kriteria ini menjadi acuan

23-06-2024
Aktivitas Antimikroba Ekstrak dan Fraksi Kulit Batang Banitan (Monocarpia kalimantanensis)

Otsuka Khaera Nurmala (2024)

Banitan (Monocarpia kalimantanensis) adalah tanaman yang tumbuh di daerah Samboja, Kalimantan Timur. Aktivitas antimikroba ekstrak dan fraksi kulit batang banitan terhadap Staphylococcus aureus, Escherichia coli, dan Candida albicans belum pernah

23-06-2024
Aktivitas Antimikroba Ekstrak dan Fraksi Kulit Batang Banitan (Monocarpia kalimantanensis)

Otsuka Khaera Nurmala (2024)

Banitan (Monocarpia kalimantanensis) adalah tanaman yang tumbuh di daerah Samboja, Kalimantan Timur. Aktivitas antimikroba ekstrak dan fraksi kulit batang banitan terhadap Staphylococcus aureus, Escherichia coli, dan Candida albicans belum pernah

23-06-2024
Isolasi dan Karakterisasi Jamur Endofit Daun Belimbing Hutan (Cnestis palala (Lour.) Merr)

Nurvidya Sistha Azzahra (2024)

Belimbing hutan (Cnestis palala (Lour.) Merr) dikenal sebagai tanaman khas Kalimantan Timur yang umumnya digunakan sebagai obat penyakit dalam, obat pasca melahirkan, sakit perut dan gangguan saluran kemih oleh masyarakat sekitar. Khasiat dari be

23-06-2024
Pengaruh Beberapa Variasi Konsentrasi Kitosan terhadap Potensial Zeta Nanopartikel Ekstrak Bawang Dayak (Eleutherine bulbosa)

Nurul Fadhilah (2024)

Ekstrak umbi bawang dayak (Eleutherine bulbosa) mengandung alkaloid, flavonoid, dan saponin yang memiliki aktivitas sebagai antioksidan dan antidiabetes. Bioavailabilitas ekstrak umbi bawang dayak secara teori dapat ditingkatkan dengan memperkeci

23-06-2024
Karakteristik Teh Herbal Daun Kersen (Muntingia calabura L.) dan Daun Salam (Syzygium polyanthum) sebagai Antioksidan

Nurfitri (2024)

Antioksidan dapat melindungi sel tubuh dari kerusakan yang disebabkan radikal bebas. Radikal bebas dapat merusak sel serta jaringan tubuh. Tubuh memiliki antioksidan alami tetapi tidak dalam jumlah besar sehingga tubuh membutuhkan antioksidan yan

23-06-2024
Kajian Metabolit Sekunder dan Potensi Antibakteri Daun Banitan (Monocarpia kalimantanensis)

Nugra Ilmahdi (2024)

Tanaman Banitan (Monocarpia kalimantanensis) merupakan tanaman berfamili Annonaceae yang dapat dijumpai di Samboja, Kalimantan Timur. Tujuan dari penelitian ini adalah mengidentifikasi dan mengetahui kandungan senyawa metabolit sekunder, dan Akti

23-06-2024
Skrining Fitokimia dan Pengujian Toksisitas Ekstrak Etanol Buah Mangrove (Sonneratia ovata) dengan Metode Brine Shrimp Lethality Test (BSLT)

Noor Fitriani (2024)

Tanaman mangrove (Sonneratia ovata) memiliki manfaat sebagai ekologi, bahan pangan dan juga sebagai bahan tradisional dalam pengobatan asma, menurunkan panas, pengobatan ambeien, nyeri otot, sakit pinggang, sakit tulang, sakit persendian dan hepa

23-06-2024
Optimasi Pembuatan Nanopartikel Ekstrak Bawang Dayak (Eleutherine bulbosa (Mill.) Urb.) Berdasarkan Konsentrasi Kitosan

Nintra Mahdan Liranti (2024)

Ekstrak bawang dayak (Eleutherine bulbosa (Mill.) Urb.) diketahui memiliki aktivitas antibakteri yang kuat sehingga berpotensi untuk dikembangkan menjadi sistem penghantaran nanopartikel. Polimer kitosan memiliki kelebihan untuk menghantarkan zat

23-06-2024
Validasi Metode dan Penetapan Kadar Kafein Menggunakan Spektrofotometri UV-Vis

Nia Fevniaty Rupa (2024)

Kafein merupakan salah satu alkaloid yang terkandung dalam kopi. Kafein pada kopi memiliki efek farmakologis yang bermanfaat secara klinis, seperti merangsang sistem saraf pusat, menghilangkan rasa lelah dan mengantuk. Penelitian ini bertujuan un

23-06-2024
Skrining Fitokimia dan Karakterisasi Minyak Biji Kemiri (Aleurites moluccana L.)

Muhammad Azril Rizqullah (2024)

Kemiri merupakan tanaman yang menarik, khususnya aktivitasnya sebagai penguat rambut serta aktivitas antibakterinya. Berbagai teknik dapat dilakukan untuk mendapatkan minyak biji kemiri, salah satunya dengan metode sangrai. Metode ini merupakan m

23-06-2024
Karakteristik Ekstrak Daun Kersen (Muntingia calabura L.) sebagai Kandidat Bahan Aktif dalam Formulasi Gel Sleeping Mask

Mirda Fitria Islamika (2024)

Tumbuhan kersen (Muntingia calabura L.) merupakan salah satu tumbuhan yang memiliki aktivitas antioksidan. Kandungan fitokimia dalam tanaman kersen meliputi flavonoid, terpenoid, steroid, fenolik, saponin dan tanin. Kandungan ini menjadikan tumbu

23-06-2024
Penentuan Nilai Sun Protection Factor (SPF) Ekstrak Etanol Rimpang Kunyit Hitam (Curcuma caesia ROXB.) dengan Metode Spektrofotometri UV-Vis

Miranda Ibau (2024)

Kunyit hitam (Curcuma caesia ROXB.) merupakan salah satu spesies dari kunyit, dari family Zingberaceae yang memiliki aktivitas antioksidan yang tinggi dan memiliki hubungan erat dengan aktivitas tabir surya yang merupakan senyawa untuk menyerap a

23-06-2024
Profil Kromatografi Lapis Tipis Antioksidan Tumbuhan Gulma: Axonopus compressus (Sw.) P. Beauv dan Digitaria ciliaris (Retz.) Koeler

Mersi (2024)

Gulma merupakan spesies tumbuhan yang tumbuh disekitar tanaman budidaya dan sering dianggap sebagai tumbuhan pengganggu yang tidak diinginkan karena dianggap merugikan. Tumbuhan gulma yang sering dianggap mengganggu ini dapat dimanfaatkan khususn

23-06-2024
Efek Beta Sitosterol dan Kunyit Hitam (Curcuma caesia) Terhadap Berat Badan dan Abnormalitas Hati pada Mencit (Mus musculus) yang Diinduksi Etanol

Jihaan Nazhiirah Ilhaam (2024)

Etanol dapat merusak fungsi hati seperti perlemakan hati, hepatitis, dan sirosis. Perlemakan pada hati disebabkan oleh penumpukan lemak pada sel hati. Kunyit hitam (Curcuma caesia) memiliki senyawa metabolit sekunder, kurkumin dengan aktivitas he

23-06-2024
Formulasi Sediaan Serum Wajah dari Ekstrak Sarang Burung Walet

Ina Annisa Rahmadina (2024)

Sarang burung walet (Edible bird’s nest) termasuk dalam family Apodidae. Sarang burung walet mengandung beberapa protein dan asam amino, glutathione serta antioksidan. Sarang burung walet juga mengandung EGF (Epideral grow factor)yang berfungsi

23-06-2024
Uji Efek Antidiare Ekstrak Rimpang Kunyit Hitam (Curcuma caesia Roxb.) terhadap Mencit (Mus musculus)

Icha Safitri (2024)

Diare merupakan penyakit yang ditandai dengan peningkatan frekuensi defekasi dan penurunan konsistensi feses disebabkan oleh gangguan absorpsi air dan elektrolit di dalam usus. Kunyit hitam disebut sebagai tanaman yang memiliki khasiat sebagai ob

23-06-2024
Pengaruh Kemasan Penyimpanan terhadap Kadar Senyawa Non Spesifik Kemangi (Ocimum basilicum L.) pada Suhu Tertentu

Haani Adilah (2024)

Kemangi (Ocimum basilicum L.) mengandung senyawa fenolik paling banyak di antara senyawa lainnya. Kondisi tersebut berperan kepada penghitaman daun kemangi yang dapat menurunkan nilai ekonomi dan kualitas sehingga dibutuhkan kemasan penyimpanan t

23-06-2024
Formulasi Sediaan Sabun Cair Ekstrak Etanol Daun Afrika (Vernonia Amygdalina Delile) dan Aktivitas Antibakterinya

Ervina Irmaya Sagita (2024)

Secara empiris daun afrika (Vernonia amygdalina delile) telah banyak digunakan oleh masyarakat Indonesia sebagai tumbuhan obat, salah satunya penyakit yang disebabkan oleh bakteri. Sabun cair merupakan sabun yang memiliki bentuk cairan menghasilk

23-06-2024
Uji Aktivitas Mukolitik dari Ekstrak Etanol Daun Sirsak (Annona muricata Linn) Menggunakan Mukosa Usus Sapi Secara In Vitro

Dea Sefiana Putri (2024)

Daun sirsak (Annona muricata Linn) merupakan salah satu tanaman obat tradisional yang belum banyak diteliti penggunaannya sebagai obat batuk. Batuk merupakan gejala adanya gangguan pada saluran pernafasan dan seringkali menyebabkan rasa tidak nya

23-06-2024
Hubungan Pelayanan Informasi Obat dengan Pengetahuan dan Tingkat Kepatuhan Pasien Hipertensi di Puskesmas Kerang Kecamatan Batu Engau

Dayuh Anggun Mandalika (2024)

Salah satu cara untuk menanggulangi hipertensi adalah meningkatkan pengetahuan dan kepatuhan pasien dalam pengobatan dengan cara pemberian Pelayanan Informasi Obat. Tujuan penelitian ini untuk mengetahui karakteristik, pengetahuan dan tingkat k

23-06-2024
Pola Pengobatan pada Pasien Malaria di Rumah Sakit Umum Daerah (RSUD) Timika, Kabupaten Mimika

Christin Claritha Mote (2024)

Malaria merupakan penyakit yang menular disebabkan oleh parasit Plasmodium (kelas Sporozoa) yang menyerang sel darah merah pada tubuh manusia, malaria sangat tinggi di daerah endemik salah satunya dipropinsi papua kususnya dikabupaten mimika. Pen

23-06-2024
Analisis Kadar Flavonoid Total Ekstrak Etanol Daun Kelakai Merah (Stenochlaena palustris (Burm F.) Bedd) Berbantu Ultrasonik

Chisilia Brydhita Karangan (2024)

Kelakai merah merupakan tanaman khas kalimantan yang banyak digunakan sebagai obat. Tanaman ini dilaporkan memiliki banyak kandungan senyawa metabolit sekunder diantaranya senyawa golongan fenolik dan flavonoid. Penelitian ini bertujuan untuk men

23-06-2024
Formulasi Sediaan Lip cream Ekstrak Etanol Bunga Asoka (Ixora coccinea) sebagai Pewarna Alami

Chintiya Vera Nanda (2024)

Bunga asoka (Ixora coccinea) memiliki pigmen warna yang dapat digunakan sebagai pewarna alami pada kosmetik dekoratif. Namun penggunaan pewarna alami pada kosmetik dekoratif masih kurang dan permintaan penggunaan kosmetik dekoratif terutama lip c

23-06-2024
Skrining Fitokimia dan Optimasi Basis Spray Gel Ekstrak Etanol Kulit Bawang Putih (Allium sativum L.) sebagai Anti Jerawat

Brilian Dwisaputra Bandu (2024)

Spray gel termasuk kedalam sediaan topikal farmasi yang dapat bertahan lama ketika disemprotkan pada kulit, karna tanpa adanya kontak fisik sediaan ini dapat mengurangi limbah dan risiko terkena penyakit kulit seperti jerawat. Tujuan dari penelit

23-06-2024
Pengaruh Kemoterapi terhadap Kadar Hematologi pada Pasien Kanker Payudara di RSUD dr. Kanujoso Djatiwibowo Balikpapan

Annisa Nabilah (2024)

Kanker payudara merupakan penyakit keganasan pada jaringan payudara yang dapat berasal dari epitel duktus maupun lobulusnya. Terapi kanker payudara dapat dilakukan dengan beberapa macam terapi, salah satunya adalah kemoterapi. Efek samping kemote

23-06-2024
Analisis Karakteristik Dismenore pada Remaja Putri

Alfenia Rahmayanti (2024)

Nyeri haid atau dismenore adalah nyeri yang dirasakan pada saat menstruasi sehingga dapat mengganggu aktifitas sehari-hari wanita. Biasanya wanita mengalami rasa yang tidak nyaman pada saat menstruasi, seperti keram dan biasanya disertai mual dan

23-06-2024
Profil Fitokimia dan Uji Aktivitas Antibakteri Ekstrak Kulit Buah Nanas (Ananas comosus (L.) Merr)

Aisyah Mursidah (2024)

Buah Nanas (Ananas comosus (L.) Merr) adalah salah satu tanaman yang banyak dikonsumsi oleh masyarakat. Namun pemanfaatan buah nanas lebih banyak pada daging buahnya saja sedangkan kulit buahnya dibuang dan menjadi limbah. Padahal di dalam kulit

23-06-2024
Tingkat Pengetahuan, Sikap dan Perilaku terhadap Resistensi dan Penggunaan Antibiotik pada Masyarakat di Desa Kota Bangun Seberang

Riska Febriyanti (2024)

Antibiotik merupakan obat yang cukup tinggi digunakan di Indonesia untuk mengobati infeksi. Namun, rendahnya pengetahuan masyarakat tentang antibiotik menyebabkan penggunaannya menjadi tidak tepat. Ketidaktepatan penggunaan antibiotik pada akhirn

23-06-2024
Kajian Profil Pengobatan pada Pasien COVID-19 di Rumah Sakit X Kota Samarinda Tahun 2020

Himmatul Ulya (2024)

COVID-19 atau Coronavirus Disease 2019 merupakan penyakit penyebab infeksi Severe Acute Respiratory Syndrom (SARSCoV-2) yang menyerang saluran pernapasan hingga organ lain pada manusia. Proses transmisi yang cukup tinggi antar manusia menyebabkan

23-06-2024
Pengaruh Hubungan Karakteristik dan Pengaruh Pemberian Jus Buah Naga Merah (Hylocereus Polyrhizus) dan Jus Buah Pepaya (Carica Papaya L.) pada Penderita Hipertensi

Yeni Kurniasari Tri Susilowati (2024)

Hipertensi adalah tekanan darah arteri yang meningkat dimana tekanan darah sistolik <130 mmHg dan tekanan darah diastolik <80mmHg. Prevalensi hipertensi di Kalimantan Timur sebesar 29,6% pada tahun 2018. Tingginya angka kejadian hipertens

23-06-2024
Profil Metabolit Sekunder, Kelarutan, dan Aktivitas Tabir Surya Ekstrak Etanol Daun Sungkai (Paronema canescens Jack)

Putri Sekardjati (2024)

Tumbuhan Sungkai (Paronema canescens Jack) secara empiris digunakan oleh masyarakat suku Dayak untuk mengobati berbagai macam penyakit. Ekstrak daun sungkai memiliki aktivitas tabir surya kategori ultra dengan nilai SPF (Sun Protecting Factor) pa

23-06-2024
Pengaruh Pemberian Jus Tomat (Solanium lycopersicum) dan Melon (Cucumis melo L.) terhadap Penurunan Tekanan Darah pada Penderita Hipertensi

Siti Munawaroh (2024)

Prevalensi hipertensi di Indonesia tahun 2018 sebesar 34,1%. Prevalensi hipertensi usia diatas 18 tahun tertinggi di Provinsi Kalimantan Selatan sebesar 44,1?n peringkat ke tiga penderita hipertensi adalah kalimantan timur sebasar 39,3%. Buah t

23-06-2024
Skrining Fitokimia dan Uji Aktivitas Antibakteri Ekstrak Daun Bidara (Ziziphus mauritiana) terhadap Bakteri Propionibacterium acnes

Lia Novita Alydrus (2024)

Bidara (Ziziphus mauritiana) merupakan salah satu tanaman di Indonesia yang telah banyak dimanfaatkan sebagai pengobatan tradisional. Salah satu khasiat yang terdapat pada tanaman ini ialah sebagai antibakteri. Tujuan dari penelitian ini untuk me

23-06-2024
Formulasi Sediaan Lotion dari Ekstrak Etanol Daun Kersen (Muntingia calabura L.) Sebagai Tabir Surya

Ina Indriyani (2024)

Tabir surya merupakan sediaan kosmetik yang digunakan untuk menyerap sinar UV sehingga dapat mengurangi jumlah radiasi UV yang berbahaya pada kulit. Daun kersen (Muntungia calabura L) adalah salah satu herbal tropis yang dilaporkan memiliki kandu

23-06-2024
Identifikasi Metabolit Sekunder Minyak Atsiri Kulit Jeruk Manis Pontianak (Citrus nobilis Lour.) Menggunakan Metode Ekstraksi Microwave Hydrodistillation

Dinda Hariyanti (2024)

Jeruk manis pontianak (Citrus nobilis Lour.) merupakan salah satu komoditas unggulan tanaman holtikultura di Kalimantan Barat, Pontianak. Umumnya, kulit jeruk di Indonesia hanya dibuang begitu saja padahal kulit jeruk memiliki banyak khasiat terl

23-06-2024
Skrinning Fitokimia Infusa Bawang Putih (Allium sativum) dan Infusa Kemangi (Ocimum basilicum)

Nur Aulia (2024)

Bawang putih (Allium sativum) dan daun kemangi (Ocimum basilicum) merupakan tanaman yang biasa di konsumsi dan juga digunakan sebagai obat herbal. Bawang putih (Allium sativum) diketahui mengandung senyawa flavonoid, saponin, allicin. Sedangkan

23-06-2024
Optimasi Basis Sediaan Masker Gel Peel off dan Skrining Fitokimia Ekstrak Etanol Bunga Telang (Clitoria ternatea L.)

Nor Sinta Hidayati (2024)

Bunga telang (Clitoria ternatea L.) merupakan tumbuhan merambat yang masuk ke dalam suku Febaceae. Masker gel peel off adalah sediaan kosmetik berbentuk gel yang dioleskan pada kulit wajah dan dibiarkan hingga mengering. Tujuan penelitian ini ada

23-06-2024
Profil Metabolit Sekunder dan Uji Aktivitas Antioksidan dari Fraksi Etanol Akar Bajakah (Uncaria nervosa Elmer)

I Putu Agus Yudiane (2024)

Kalimantan merupakan pulau terbesar kedua di Indonesia yang dikenal dengan keanekaragaman tumbuhan dan dimanfaatkan sebagai bahan obat tradisional oleh masyarakat setempat. Potensi yang telah di data saat ini belum menunjukkan potensi tumbuhan ob

23-06-2024
Skrining Fitokimia dan Profil KLT Antioksidan Ekstrak Metanol dan Ekstrak Partisi N-Heksana Akar Bajakah (Uncaria nervosa Elmer)

Elisabeth James Randan (2024)

Tumbuhan Bajakah dengan nama ilmiah Uncaria nervosa Elmer merupakan salah satu tumbuhan yang berasal dari pulau Kalimantan, dan digunakan oleh masyarakat Dayak sebagai obat tradisonal. Telah dilakukan berbagai penelitian yang menyajikan infomasi

23-06-2024
Laporan Kasus: Asuhan Kefarmasian Penggunaan Obat Flu Anak

Niken Indriyanti (2024)

Asuhan kefarmasian pada penggunaan obat flu anak sangat diperlukan supaya keluarga pasien bisa memberikan obat yang tepat kepada anaknya. Banyaknya informasi di internet maupun kebiasaan menggunakan obat tertentu menjadi masalah jika obat yang di

23-06-2024
Efek Toksik Pemberian Ekstrak Etanol Daun Mekai (Albertisia papuana Becc.) Terhadap Mencit

Febrianto Ubang (2024)

Daun mekai merupakan tanaman khas Kalimantan yang dimanfaatkan oleh masyarakat Dayak secara tradisional sebagai terapi untuk penyakit seperti hipertensi, stroke, kanker. Secara ilmiah daun mekai memiliki potensi sebagai anti plasmodium, antibakte

23-06-2024
Studi Etnofarmasi Tanaman Berkhasiat Obat pada Suku Paser di Desa Samurangau dan Desa Tepian Batang Kabupaten Paser

Nabila Nur Rahma Hidayat (2024)

Informasi mengenai tanaman berkhasiat obat yang digunakan secara tradisional pada suku- suku di indonesia masih kurang dieksplorasi, salah satunya pada suku Paser Kalimantan Timur. Oleh karena itu, penelitian ini bertujuan untuk mendokumentasikan

23-06-2024
Formulasi Tablet Chlorpheniramine Maleat (CTM) dengan Pati Ampas Tahu sebagai Bahan Pengisi dalam Pemanfaatan Limbah Tahu di Samarinda

Nurdewi Halik (2024)

Ampas tahu adalah hasil sisa pemerasan gilingan kedelai pada produk tahu yang memiliki karbohidrat tinggi sehingga dapat dikelola menjadi pati yang berpotensi untuk dimanfaatkan sebagai bahan pengisi pada sediaan tablet. Penelitian ini bertujuan

23-06-2024
Efektivitas Antihipertensi Kombinasi Jus Mentimun (Cucumis sativus L.), Rebusan Daun Kelor (Moringa oleifera Lam.) dan Madu Kelulut pada Pasien Hipertensi di Puskesmas Air Putih Samarinda

Lina Nur Amelia (2024)

Hipertensi atau tekanan darah tinggi ialah penyakit silent killer yang dapat membunuh secara diam diam tanpa gejala yang timbul. Faktor resiko yang dapat menyebabkan hipertensi yaitu usia, jenis kelamin, genetik, riwayat penyakit, dan gaya hidup.

23-06-2024
Uji Aktivitas Antioksidan Ekstrak Etanol Buah Belimbing Wuluh (Averrhoa bilimbi L.)

Elsa Akbar Wati (2024)

Belimbing Wuluh (Averrhoa bilimbi L.) termasuk dalam famili oxalidaceae. Tanaman buah Belimbing Wuluh memiliki kandungan golongan senyawa oksalat, fenol, dan flavonoid yang bersifat sebagai antioksidan dan antibakteri. Pada penelitian sebelumnya

23-06-2024
Aktivitas Antioksidan Kombinasi Sari Daun Ketapang (Terminalia Catappa) dan Rimpang Jahe (Zingiber Officinale)

Hanny Chynthia Vehrawati (2024)

Daun ketapang merupakan tanaman yang memiliki antioksidan yang sangat tinggi namun belum termanfaatkan dengan baik. Selain ketapang, jahe juga diketahui memiliki aktivitas antioksidan yang cukup tinggi. Meski begitu, kedua tanaman ini memiliki an

23-06-2024
Formulasi Snack Bar Tinggi Kalsium dari Tepung Limbah Cangkang Telur sebagai Sumber Nutrisi Kalsium

Yeni Fitri Handayani (2024)

Osteoporosis merupakan kelainan pada tulang yang disebabkan oleh gangguan metabolisme dikarenakan ketidakmampuan tubuh untuk menyerap dan memanfaatkan zat-zat yang diperlukan dalam proses pematangan tulang. Salah satu upaya yang dapat dilakukan u

23-06-2024
Analisis Efek Samping Penggunaan Obat Antituberkulosis (OAT) di Instalasi Rawat Jalan RSD BLUD dr. H. Soemarno Sosroatmodjo Tanjung Selor

Fridya Maulitha (2024)

Tuberkulosis Paru (TB) merupakan penyakit menular yang disebabkan oleh kuman mycobacterium tuberculosis. Penyakit ini diobati dengan Obat Antituberkulosis (OAT) menggunakan obat kombinasi sehingga sebagian besar pasien mengalami efek samping. Pe

23-06-2024
Systematic Review: Potential of Curcumin Compounds as Immunostimulants in the Prevention of SARS-CoV 2 Virus

Burhan Ma’arif (2024)

Curcumin is a compound from the turmeric rhizome plant (Curcuma longa) which has immunostimulating activity. This activity has been tested pre-clinically in vitro, in vivo, and in silico so that it has the potential to be used as raw material for

23-06-2024
Systematic Review: Phytochemical Content and Pharmacological Effects of Chrysanthemum Sp.

Roihatul Mutiah (2024)

Chrysanthemum sp is a plant that is often used by the community as an ornamental plant, drink and traditional medicine. This study aims to examine the plant Chrysanthemum sp from the aspect of phytochemical and pharmacological activity. The revie

23-06-2024
Effect of Addition Virgin Coconut Oil (VCO) on Physical Stability and SPF Value of Sunscreen Cream Combination of Zinc Oxide and Titanium Dioxide

Bella Corry Jayati (2024)

Virgin Coconut Oil (VCO) is one of the natural ingredients used as antioxidants because of the high saturated fatty acids that cause VCO to be resistant to oxidation. In this research, a combination of zinc oxide (ZnO) and titanium dioxide (TiO2)

23-06-2024
Prediction of Compounds from 96% Ethanol Extract of Marsilea crenata Presl. Leaves in Increasing Estrogen Receptor-a Activation

Burhan Ma’arif (2024)

Women who experience menopause will experience estrogen deficiency which will have an impact on their health; one of which will increase the risk of neurodegenerative. Phytoestrogen compounds in Marsilea crenata are able to provide activity after

23-06-2024
Phytochemical and Pharmacology Effect of Calotropis Gigantea as Anti Cancer Therapy: Systematic Review

Roihatul Mutiah (2024)

The high prevalence of cancer in the world makes many researchers look for alternative therapies that can be used to treat cancer. One of them is by using traditional plants, namely Calotropis gigantea R.Br. This is due to the presence of alkaloi

23-06-2024
In Silico Antiosteoporosis Activity of 96% Ethanol Extract of Chrysophyllum cainito L. Leaves

Burhan Ma’arif (2024)

Estrogen deficiency causes various health problems in postmenopausal women, including osteoporosis. Phytoestrogens are emerging as potential estrogen alternatives with minimal side effects. This study aimed to predict the antiosteoporosis activit

23-06-2024
Formulation and Characterization of SNEDDS of Dayak Onion Extract with Comparative Variation of Surfactants, Co-Surfactants, and Palm Oil

Rahmi Annisa (2024)

Self-Nanoemulsifying Drug Delivery System (SNEDDS) is a thermodynamically stable drug administration unit with the capacity to increase the solubility of active pharmaceutical ingredients (API) and bioavailability. In addition, dayak onio

23-06-2024
Drug Utilization Study of Diuretics in Children with Hydrocephalus

Yen Yen Ari Indrawijaya (2024)

Hydrocephalus is a condition characterized by a dynamic imbalance between formation and absorption of cerebrospinal fluid that increases the size of intracranial space of the brain and, in some situations, an extension of the outer space of the b

23-06-2024
A Comparative Study to Enhance Medication Adherence: Pillbox vs Medication Reminder Chart

Alifia Putri Febriyanti (2024)

The main problems in geriatric patients with type 2 diabetes mellitus are polypharmacy and poor medication adherence, that can lead to increased morbidity and mortality. This study aims to find out the comparison of the effectiveness in the appli

23-06-2024
A NETWORK PHARMACOLOGY OF Camellia sinensis (GREEN TEA)

Sri Wahyuni (2024)

Network pharmacology focuses on the therapeutic concept of one-target-one-drug to network-target components to combat complex diseases. This research uses bioinformatics and high-throughput screening methods to facilitate the prediction of various

23-06-2024
THE THERAPEUTIC ROLE OF Olea Europaea IN ALCOHOL DEPENDENCE BASE IN NETWORK PHARMACOLOGY ANALYSIS

Faiznanda Awwaluddin (2024)

Alcohol dependence is a state of alcohol becoming a vital part of the life of a person who consumes it; when discontinued, it can lead to a wide range of physical and mental health disorders as well as a decrease in life productivity in people wi

23-06-2024
DISCOVERY NEW DRUG CYCELA BARBATA IN ALCOHOL USE DISORDER USING PHARMACOLOGICAL METHODS

Nuvandaru Fajar Dzikra Febriyandi (2024)

Alcohol use disorder (AUD) is a medical condition characterized by an impaired ability to stop or control alcohol use including conditions that some refer to as alcohol abuse, alcohol dependence, alcohol addiction, and the colloquial term, alcoho

23-06-2024
MOLECULAR DOCKING OF BENZIMIDAZOLE DERIVATIVE COMPOUNDS AS XANTHIN OXIDASE INHIBITOR

Tanaya Jati Dharma Dewi (2024)

Modifying the structure of a compound can increase the potency and selectivity of a compound. In designing a compound that is potent and selective, this can be done by: several methods, one of which is molecular docking. Benzimidazole, a special

23-06-2024
A COMPARATIVE ANALYSIS OF STEAM DISTILLATION AND ENFLEURAGE METHODS FOR THE EXTRACTION OF Cananga odorata FLOWER ESSENTIAL OIL

Elisa (2024)

Essential oils are made from the natural extracts of many different kinds of plants. Indonesia has a lot of potential for making essential oils that could make it the leader in the essential oil market around the world. One of them is the essenti

23-06-2024
COMPARISON OF ACUTE TOXICITY TEST OF CARDAMOM EXTRACT COMBINATION (Amomum compactum Soland. Ex Maton) AND CURCUMA (Curcuma xanthorrizha Roxb) WITH A COMBINATION OF CARDAMOM EXTRACT (Amomum compactum Soland. Ex. Maton) AND GALANGAL (Alpinia galanga L) AGAINST Artemia salina Leach BY BRINE SHRIMP LETHALITY TEST (BSLT) METHOD

Rixzal Azis Julian (2024)

Cardamom, ginger, and galangal are one of the plants that are often used as herbal medicine. Similar studies that have been carried out previously only conducted single extract tests and have not combined extracts, and compared the results of usi

23-06-2024
THE INFLUENCE OF ANALGESIC SELF-MEDICATION EDUCATION ON THE KNOWLEDGE OF HAJJ PILGRIMS

Hajar Sugihantoro (2024)

The self-medication of analgesic drugs by elderly prospective hajj pilgrims in Indonesia requires better education to enhance understanding of safe and rational drug use, thus reducing the risk of side effects. Therefore, the research aimed at pr

23-06-2024
FORMULATION AND ACTIVITY TESTING OF A PREPARATION OF CHERRY FRUIT (Muntingia calabura L.) SYRUP AS ACUTE ANTIDIARRHEA IN MICE

Widya Suci Musfirah (2024)

The problem of diarrhea is an important problem to overcome, especially in the Samarinda area, East Kalimantan Province. The number of diarrhea cases is increasing every year. In 2021, there were 34,436 cases nationally and 4,706 cases in Samarin

23-06-2024
NETWORK PHARMACOLOGY ANALYSIS OF Cananga odorata AS A TREATMENT FOR ANXIETY DISORDERS

Tri Luthfiana Maretha (2024)

Anxiety disorder is a psychological disorder associated with the existence of mental disorders and experiencing constant anxiety. In C. odorata, part of the flower has the potential as a sedative for the nervous system and for dealing with anxiet

23-06-2024
BIOAVAIBILITY EVALUATION AND MOLECULAR DOCKING OF Cananga odorata PLANT AS ANTI-INFLAMMATORY POTENTIAL AGAINST CROHN’S DISEASE

Shindy Annisadila (2024)

Crohn's disease is a chronic inflammatory bowel disease (IBD) that affects the digestive tract. One of the potential targets for this disease is LRRK2. Kenanga (Cananga odorata) is known to have anti inflammatory effects. The study aims to identif

23-06-2024
Melaleuca Leucadendra PHARMACOLOGICAL NETWORK FOR IDENTIFYING POTENTIAL TARGET OF ALCOHOL DEPENDENCE

Risma Ayu Setiawan (2024)

Melaleuca leucadendra (ML) contains a compound that is potentially a candidate for alcohol dependence. Alcohol dependence is defined by desire, tolerance, anxiety with alcohol, and continuing to drink even though the consequences are dangerous. T

23-06-2024
COMPARISON OF BLOOD PRESSURE IN HYPERTENSIVE PATIENTS WITH MONOTHERAPY AND COMBINATION ANTIHYPERTENSIVE THERAPY

Novely Dwita Ramadhani (2024)

Background: Hypertension is a cardiovascular risk factor that is closely related to the patient's systolic and diastolic blood pressure profile. Objective: This study aims to determine the comparison of systolic and diastolic blood pressure profi

23-06-2024
POTENTIAL OF SECONDARY METABOLITE OF Jasminum sambac AS DIABETES MELLITUS MEDICINE BY MOLECULAR DOCKING METHOD

Mochammad Rehan Alghifari (2024)

Diabetes mellitus (DM) is a non-infectious disease with a high prevalence in Indonesia. The study explored the potential of the phytochemical component of Jasminum sambac to treat DM. The potential of Jasminum. sambac as a candidate for DM therap

23-06-2024
A NETWORK PHARMACOLOGY OF BELUNTAS (Pluchea Indica) ON IMMUNITY CASES

M. Amir Fauzi (2024)

COVID-19 is classified as an outbreak related to the human immune system. The process of spreading was indeed quick, which made this outbreak a particularly dangerous pandemic. As of March 10, 2023, Indonesia had recorded 6,738,225 positive cases

23-06-2024
IN SILICO POTENTIAL ANALYSIS OF ACORUS CALAMUS AS A MENTAL DEPRESSION THERAPY

Fitria Dwi Damayanti (2024)

Depression is a common but serious mood disorder. This disease causes severe symptoms that affect one's emotions, thoughts, and daily activities, such as sleep, eating, or working. According to the National Youth Mental Health Survey of Indonesia

23-06-2024
IN SILICO ANALYSIS OF SECONDARY METABOLITES OF Clerodendrum Inerme AS A POTENTIAL ANTIDIABETES COMPOUNDS

Fauzan Hilmy (2024)

Clerodendrum inerme can potentially alleviate diabetes, but little is known about its molecular mechanisms. This study aimed to investigate the chemical compound of C. inerme and its molecular mechanism to treat diabetes. The KNApSAcK was used to

23-06-2024
A NETWORK PHARMACOLOGY OF LEMONGRASS (Cymbopogon citratus) ON COVID-19 CASES

Dominyda Vebrianto Saputro (2024)

Various ways and treatment efforts are carried out to avoid the severe impact of COVID-19 cases, one of which is using plants as natural immunomodulatory agents. One of the plants that is proven to act as a natural immunomodulator is lemongrass (

23-06-2024
A RATIONALITY STUDY OF ANTIHYPERTENSIVE DRUGS USAGE IN PREECLAMPSIA PATIENTS IN THE PRIVATE HOSPITAL

Dhani Wijaya (2024)

Preeclampsia is a hypertension that happens in pregnancy of ? 20 weeks and occurs with proteinuria. Preeclampsia is also the highest cause of mother’s death second place in Indonesia. According to that, a study of rationality is needed concerni

23-06-2024
A NETWORK PHARMACOLOGY OF BROTOWALI (Tinospora cordifolia) ON IMMUNITY CASES

Awang Farhan Ferdyan Syah Susanto (2024)

COVID-19 is a disease outbreak related to the human immune system. The process of spreading very quickly makes this outbreak a dangerous pandemic. COVID-19 cases in 2020 in Indonesia, positive cases were reaching 1,089,308 people with a death rat

23-06-2024
ANALYSIS OF HOSPITAL AND INA-CBG’S RATES OF JKN OUTPATIENT IN GENTENG REGIONAL PUBLIC HOSPITAL IN 2021

Wiwik Triyudawati (2024)

The Government's effort improves the health status of the Indonesian people by establishing a Jaminan Kesehatan Nasional (JKN). JKN’s program was formed by Badan Penyelenggara Jaminan Sosial Kesehatan (BPJS Kesehatan). Payment of health costs b

23-06-2024
FORMULATION AND EVALUATION OF HERBAL HYDROGEL CONTAINING Ageratum Conyzoides LEAVES ETHANOL EXTRACTS

Annisa Kartika Sari (2024)

Ageratum conyzoides Linn. can be used for wound healing. The main compound found in Ageratum leaves is 5'-methoxy nobiletin, a class of polymethoxyflavone that may treat pain and inflammation. The pharmaceutical preparation chosen for the develop

23-06-2024
EVALUATION AND PHYSICAL STABILITY EFFERVESCENT POWDER OF OKRA LEAVES EXTRACT (Abelmoschus esculentus) AS AN ANTIDIABETIC SUPPLEMENT

Agnis Pondineka Ria Aditama (2024)

Diabetes Mellitus (DM) is a disease characterized by hyperglycemia and the most frequently encountered is type 2 which requires oral anti-diabetic therapy. Economic and socio-cultural factors also influence people in making their choice on altern

23-06-2024
Terapi Bekam (Hijamah) dalam Perspektif Islam dan Medis

Hakmi Hidayat (2024)

Umat muslim memiliki kitab suci Al-Quran dan hadis sebagai sumber hukum yang utama dalam berbagai permasalahan termasuk kesehatan. Salah satu terapi pengobatan yang disebutkan dalam Al-Qur’an dan hadis adalah bekam yakni suatu proses mengeluark

23-06-2024
Kandungan Buah Delima (Punica granatum L.) dalam Perspektif Al-Qur'an, Sunnah, dan Sains

Sugeng Ali Mansur (2024)

Delima menjadi salah satu dari sekian buah yang disebutkan Allah Swt. dalam al-quran. Yakni Q.S. Al An’am ayat 99 dan Q.S. Ar-Rahman ayat 68, dengan istilah Al-rumman (bahasa Arab). Buah Delima menjadi istimewa lantaran merupakan salah satu buah

23-06-2024
The Benefits of Removing Dirty Blood with Traditional Cupping Treatment

Muhammad Amiruddin (2024)

In daily life, Muslims are ordered to behave by the teachings in the Al-Quran and the sunnah of the Prophet Muhammad, including regarding health. In the world of health, it is known that alternative medicine in the style of Rasulullah SAW is know

23-06-2024
Implementation of Ruqyah as an Alternative to Islamic Medicine in Indonesia

Kartika Ratnasari (2024)

One of the religious therapies in the life of Muslims is ruqyah. Ruqyah is a prayer accompanied by dhikr to Allah Almighty by reciting the holy verses of the Quran and hadith. Ruqyah is used to cure mental disorders, physical illnesses, and other

23-06-2024
Acetylation of Emodin and Cytotoxic Activity Effect Against HepG2 Cell Lines

Firdayani (2024)

Emodin (1,3,8-trihydroxy-6-methyl-9,10-anthraquinone) is an anthraquinone bioactive compound used as a lead compound because it exhibits potential anticancer properties. Structural modifications were made at the C3 position and its relationship t

23-06-2024
Determination of Quercetin in Extracts and Herbal Products of Phyllanthus niruri by TLC Densitometry Method

Bachtiar Rifai Pratita Ihsan (2024)

Phyllanthus niruri has many pharmacological activities such as antioxidant, anti-inflammatory and anticancer. Phyllanthus niruri has been widely developed from extracts into herbal products. The flavonoid quercetin became an analytical marker com

23-06-2024
Analysis of Antidiabetic Potential of Palmitic Acid Compounds Through In Silico Activation

Ardellya Elfidaa Salsabila (2024)

Diabetes Mellitus is a condition where the body's sugar level exceeds the blood's normal limit. Type 2 Diabetes Mellitus is the most common type of diabetes and is a chronic disease caused by insulin resistance and beta-cell dysfunction, resultin

23-06-2024
Scoping Review: Analysis of Alcohol Levels in Food and Beverages Using Gas Chromatography

Suryanto (2024)

Islamic teachings explain that food or beverage should not be consumed with more than 0.5% alcohol because it is categorized as khamr, which is unlawful. In determining the levels of foods or beverages that contain alcohol, one of which is the ga

23-06-2024
Antineuroinflammatory Properties of Compounds from Ethyl Acetate Fraction of Marsilea crenata C. Presl. Against Toll-Like Receptor 2 (3A7B) In Silico

Burhan Maarif (2024)

Parkinson's disease (PD) can be triggered by overactive TLR2 due to ?-synuclein abnormalities and aggregation. Marsilea crenata C. Presl. leaves inhibit neuroinflammatory progression. This study aimed to predict the antineuroinflammatory activity

23-06-2024
The Effect of Schleichera oleosa L. on HbA1c Levels in Alloxan Induced Rats

Akbar Awaluddin (2024)

Diabetes mellitus is a chronic disease that occurs due to the failure of the pancreas to produce sufficient insulin, or the body cannot use the insulin it makes effectively. The HbA1c (glycated hemoglobin) levels show an alteration in blood gluco

23-06-2024
Review: Studi Kandungan Fitokimia, Aktivitas Antioksidan, dan Toksisitas Jamblang (Syzygium cumini L.)

I Putu Bagus Kurniadinata (2024)

Jamblang (Syzygium cumini L.) memiliki berbagai dampak untuk kesehatan, salah satunya sebagai antioksidan. Antioksidan berfungsi untuk mencegah dan memulihkan kerusakan pada sel-sel dalam tubuh, terutama yang disebabkan oleh pengaruh negatif dari

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antibakteri Daun Pepaya (Carica Papaya L.)

Krisna Wahyu Nugraha (2024)

Tumbuhan pepaya (Carica papaya L.) yang termasuk dalam famili Caricaceae telah dilaporkan memiliki aktivitas sebagai agen antibakteri. Review ini dibuat dengan tujuan untuk mengkaji penelitian penelitan terkini mengenai aktivitas antibakteri dan

23-06-2024
Suplementasi Lutein Dari Tanaman Sebagai Anti Aging

Ni Kade Ayu Suci Novira Anggriani (2024)

Penuaan kulit merupakan masalah dermatologi yang ditandai dengan menghilangnya kemampuan jaringan secara perlahan untuk memperbaiki dan mempertahankan struktur serta fungsi fisiologi kulit secara normal. Penuaan kulit dipengaruhi oleh faktor intr

23-06-2024
Uji Kelarutan Flavonoid Ekstrak Kulit Salak Dalam Fase Minyak: Asam Oleat, Minyak Zaitun dan Isopropil Miristat

Florencya (2024)

Salak (Salacca zalacca) atau snake fruit merupakan buah asli Indonesia berjenis palma yang memiliki kulit bersisik berwarna coklat. Jenis salak yang banyak dibudidayakan di Bali yaitu salak bali dan salak gula pasir. Kulit salak mengandung senyaw

23-06-2024
Potensi Tanaman Jeruju (Acanthus ilicifolius L.) sebagai Antiinflamasi

Ni Made Sugi Pradnyasuari (2024)

Inflamasi merupakan respon sistem kekebalan tubuh terhadap kerusakan jaringan yang dapat disebabkan oleh trauma fisik, bahan kimia beracun, atau agen mikrobiologis. Tata laksana terapi yang digunakan dalam mengatasi inflamasi saat ini diketahui

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antibakteri Kencana Ungu (Ruellia tuberosa L.)

I Kadek Adi Putra Suandana (2024)

Kencana ungu (Ruellia tuberosa L.) atau pletokan merupakan salah satu tanaman liar yang dapat tumbuh di berbagai tempat. Tanaman ini (famili Acanthaceae) diketahui mengandung senyawa senyawa fitokimia yang berpotensi sebagai antibakteri. Review a

23-06-2024
Potensi Aktivitas dari Ekstrak Bunga Telang (Clitoria ternatea L.) sebagai Antioksidan Alami dalam Bentuk Sediaan Tablet Effervescent

Putu Ayu Karunia Silawarti (2024)

Antioksidan merupakan jenis senyawa dengan manfaat untuk menghambat radikal bebas dalam tubuh. Penyakit kronis serta degeneratif dapat dicegah dengan bantuan senyawa antioksidan. Senyawa yang mampu menghasilkan efek antioksidan dapat diperoleh di

23-06-2024
Mekanisme Anti-Hipertensi dari Bunga Rosela (Hibiscus sabdariffa L.) dalam Pengobatan Berbasis Bahan Alam: A Systematic Review

Ni Pande Kadek Sinta Dewi (2024)

Hipertensi merupakan suatu penyakit yang ditandai dengan tingginya tekanan darah berupa tekanan sistolik lebih dari 140 mmHg dan tekanan diastolik lebih dari 90 mmHg. Tingginya tekanan darah dapat menyebabkan beragam komplikasi serius apabila ber

23-06-2024
Review: Kandungan Fitokimia, Aktivitas Antibakteri, dan Toksisitas dari Rambutan (Nephelium lappaceum L.)

Ni Luh Komang Wahyuni (2024)

Rambutan (Nephlium lappaceum L.) merupakan salah satu tanaman tropis yang banyak terdapat di Indonesia dan dikenal luas karena rasa manis serta aroma khasnya. Secara tradisional beberapa bagian tanaman rambutan digunakan untuk berbagai macam peng

23-06-2024
Pemanfaatan Senyawa Apigenin Bunga Chamomile (Matricaria recutita L.) dalam Sediaan Farmasi Nutrasetikal untuk Meningkatkan Kualitas Tidur

Aisah Dwi Agus Rahma Putri (2024)

Tidur merupakan keadaan dimana tubuh dan otak mengalami proses pemulihan yang sangat penting terhadap pencapaian kesehatan optimal, serta merupakan salah satu kebutuhan dasar manusia. Belakangan ini, ditemukan 21,8% penduduk dari 4.005 orang mem

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antibakteri Ekstrak Daun Kersen (Muntingia calabura L.)

Francoise Carita Pia (2024)

Resistensi mikroba terhadap agen antibakteri saat ini menjadi salah satu faktor pentingnya penggunaan obat alternatif, salah satunya yang berasal dari metabolit tumbuhan. Daun kersen (Muntingia calabura L.) merupakan tumbuhan obat yang diketahui

23-06-2024
Potensi Asam Eikosapentanoat (EPA) Pada Ganggang Merah (Gracilaria sp.) sebagai Suplementasi Nutrisi untuk Mengurangi Risiko Penyakit Kardiovaskular

Lucienne Agatha Larasati Nugraha Putri (2024)

Beberapa tahun belakangan, rumput laut telah dipandang sebagai organisme yang menjanjikan untuk dimanfaatkan sebagai penyedia senyawa aktif baru dalam pengembangan produk pangan baru (nutrasetikal). Hal ini karena metabolit sekunder yang dihasilk

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antibakteri Tanaman Buah Naga (Hylocereus spp.)

Kadek Febriyanti (2024)

Buah naga (Hylocereus spp.) yang termasuk ke dalam famili Cactaceae banyak digunakan sebagai makanan yang kaya akan vitamin. Tanaman ini telah terbukti mengandung berbagai senyawa fitokimia yang memiliki potensi sebagai agen antibakteri. Tujuan d

23-06-2024
Mekanisme Aktivitas Anti-Diabetes Dari Kandungan Senyawa Tanaman Kersen (Muntingia calabura L.): Systematic Review

Ni Kadek Yunia Pratiwi (2024)

Diabetes mellitus adalah penyakit gangguan metabolik yang ditandai dengan kadar gula yang melebihi batas normal.Prevalensi diabetes pada tahun 2021 adalah 537 juta orang dan diperkirakan akan meningkat sebesar 10,2 % pada tahun 2030 dan 10,9 % pa

23-06-2024
Potensi Stevia (Stevia rebaudiana) sebagai Suplemen Nondiabetik Penunjang Terapi bagi Penderita Diabetes Mellitus Tipe II

Luh Putu Oktavia Sandra Dewi (2024)

Diabetes Mellitus tipe II merupakan gangguan metabolik yang ditandai dengan tingginya kadar gula dalam darah. Penderita Diabetes Mellitus harus mengontrol kadar gula darah mereka dan melakukan diet medis ketat khususnya asupan gula tubuh. Stevia

23-06-2024
Pengaruh Rebusan Seledri Untuk Penurunan Kadar Purin Penderita Gout

Ida Ayu Pradnyaswari (2024)

Orang dewasa sering mengalami asam urat (Gout) karena terlalu banyak mengonsumsi makanan tinggi purin menyebabkan produk akhir metabolisme purin tubuh mengkristal. Karena kelebihan purin tidak dapat dihilangkan oleh ginjal, maka akan menumpuk di

23-06-2024
Potensi dan Efektivitas Farmakologi Ekstrak Kembang Telang (Clitoria ternatea L.) sebagai Suplemen Antidiabetes: A Systematic Review

Anak Agung Made Ari Suryawati (2024)

Diabetes melitus (DM) merupakan gangguan metabolisme kronis pada tubuh yang ditandai dengan terjadinya peningkatan kadar gula darah (hiperglikemia) yang disebabkan adanya defisiensi produksi insulin oleh sel ? pankreas. Saat ini, terapi pengobata

23-06-2024
Potensi Antikolesterol dari Bawang Putih (Allium sativum): Systematic Review

Gusti Ayu Putu Windu Lestari (2024)

Hiperkolesterolemia merupakan masalah kesehatan yang terjadi di banyak negara. Kadar kolesterol yang tinggi (hiperkolesterolemia) dapat meningkatkan risiko terjadinya penyakit jantung koroner, serangan jantung, stroke, hipertensi, dan diabetes. F

23-06-2024
Potensi Bahan Alam dalam Nutrasetikal Sebagai Pendekatan Antihipertensi: Tinjauan Terkini dan Prospek Masa Depan

Komang Tri Subawa (2024)

Nutrasetikal merujuk pada makanan atau elemen makanan yang memiliki potensi untuk memberikan manfaat baik bagi kesehatan maupun aspek medis, terutama dalam mengatasi berbagai penyakit. Nutrasetikal yang berasal dari tumbuhan atau memiliki komplek

23-06-2024
Potensi Daun Lidah Buaya (Aloe Vera L.) sebagai Suplemen untuk Mengurangi Risiko Sindrom Ovarium Polikistik

Jessica Rianty Suhendi (2024)

Sindrom ovarium polikistik atau Polycystic Ovary Syndrome (PCOS) merupakan gangguan dalam sistem endokrin yang mengakibatkan masalah kesuburan pada wanita yang berada dalam usia produktif. Penyebab dasar dari PCOS adalah tingginya rasio luteinizi

23-06-2024
Efek Nutrasetikal Kolagen Terhadap Kesehatan Kulit

Dewa Julio Angga Purnama (2024)

Kolagen merupakan protein struktural yang banyak terdapat pada kulit terutama jaringan dermis. Penurunan produksi kolagen disebabkan oleh pembentukan kompleks matriks metaloproteinase (MMP) pengurai kolagen seiring bertambahnya usia. Suplementasi

23-06-2024
Studi Literatur Potensi Ekstrak Bunga Cengkeh (Syzygium aromaticum) sebagai agen Antikanker

Ni Kadek Diah Ayu Septiandary (2024)

Berdasarkan data WHO, sebanyak 10 juta orang di dunia meninggal tiap tahunnya akibat kanker. Di Indonesia, penyakit kanker telah menduduki peringkat ke-8 di Asia Tenggara dengan angka kejadian mencapai 136 orang per 100.000 penduduk. Sampai saat

23-06-2024
Teh Daun Kelor (Moringa Oleifera) sebagai Antihipertensi

Putu Srianjani (2024)

Hipertensi adalah kondisi di mana tekanan darah dalam arteri seseorang lebih tinggi dari ambang angka normal untuk jangka lama. Hipertensi sering meningkatkan risiko berbagai komplikasi penyakit lain. Salah satu penyakit tersebut adalah seperti g

23-06-2024
Potensi Sediaan Ekstrak Bunga Telang (Clitoria ternatea L.) Sebagai Bahan Antioksidan Alami

Gede Bagus Abdi Raditya (2024)

Antioksidan adalah senyawa yang memiliki manfaat besar untuk kesehatan manusia karena mampu menghentikan reaksi oksidasi dan seringkali digunakan untuk melawan radikal bebas. Antioksidan alami adalah jenis senyawa antioksidan yang berasal dari tu

23-06-2024
Aktivitas Kandungan Bioaktif Allicin Pada Bawang Putih (Allium sativum L.) sebagai Anti Hipertensi

Ida Ayu Triona Mahadewi (2024)

Hipertensi merupakan “silent killer” dan menjadi masalah kesehatan yang masih banyak terjadi di dunia. Hipertensi merupakan suatu keadaan tekanan darah sistolik seseorang lebih dari 140/90 mmHg. Hipertensi dapat menjadi faktor risiko utama te

23-06-2024
Analisis Senyawa Flavonoid pada Jeruk Manis (Citrus sinensis L.) sebagai Pengobatan Wasir

Komang Dian Merta Sari Dewi (2024)

Wasir adalah ketika pembuluh darah normal di daerah rektum mengalami pembengkakan dan pergeseran. Tanda-tanda umum meliputi pendarahan saat melakukan buang air besar dan tonjolan di sekitar anus. Ada cara-cara untuk mencegah wasir tanpa menggunak

23-06-2024
Review: Potensi Jamur Endofit dari Divisi Alga Hijau (Chlorophyta) sebagai Antibakteri beserta Kandungan Senyawa Bioaktifnya

I G A Istri Agung Pramiari (2024)

Peningkatan risiko dalam berkembangnya beberapa agen infeksius seperti bakteri menyebabkan adanya kebutuhan agen senyawa obat baru yang konstruktif. Saat ini, jamur endofit dianggap sebagai sumber produk alami baru yang efektif untuk keperluan me

23-06-2024
Efektivitas Daun dan Buah Kersen (Muntingia calabura L.) sebagai Nutrasetikal Penurun Kadar Kolesterol pada Kondisi Hiperlipidemia

Kadek Angga Dwi Saputra (2024)

Hiperlipidemia merupakan suatu kelainan metabolik yang mengacu pada perubahan profil lipid dan lipoprotein dalam darah yang disebabkan oleh peningkatan kolesterol total, low density lipoprotein cholesterol (LDL), dan trigliserida yang disertai de

23-06-2024
Potensi Rempah Saffron (Crocus sativus L.) sebagai Nutrasetikal Anti-Hipertensi

I Gede Krishna Wira Pradnyana (2024)

Penyakit hipertensi atau dikenal juga sebagai The Silent Killer didefinisikan sebagai peningkatan tekanan darah arteri yang persisten. Dari tahun ke tahun, angka penderita hipertensi di Indonesia mengalami peningkatan yang signifikan. Hal ini dit

23-06-2024
Potensi Tanaman Pepaya (Carica papaya L.) sebagai Nefroprotektor

Wayan Dianda Sari (2024)

Ginjal merupakan organ yang dibutuhkan dalam tubuh manusia dan dikategorikan sebagai organ vital untuk melaksanakan berbagai fungsi penting meliputi detoksifikasi, pengaturan cairan ekstraseluler, homeostasis, dan ekskresi metabolit toksik. Kerus

23-06-2024
Kajian Literatur Potensi dan Mekanisme Tanaman Leunca (Solanum nigrum L.) sebagai Nutrasetikal Antiinflamasi

I Kadek Sindhu Satya Mahindra T (2024)

Inflamasi merupakan suatu respon alami tubuh dalam menanggapi rangsangan berbahaya, menghilangkan iritan, dan sel-sel rusak. Namun, aktivitas inflamasi yang berlebihan dapat menimbulkan dampak imunopatologis terhadap tubuh. Tanaman Leunca (Solanu

23-06-2024
Potensi Efek Terapeutik Propolis sebagai Pencegahan dan Pendukung Terapi Penyakit Jantung Koroner

Kadek Desi Lasminiati (2024)

Penyakit jantung koroner adalah penyebab utama kematian di seluruh dunia. Penyakit ini terjadi karena adanya penyempitan atau penyumbatan arteri koroner akibat proses aterosklerosis. Aterosklerosis dimulai dengan disfungsi endotel yang memungkink

23-06-2024
Efek Farmakologi Daun Sintrong (Crassocephalum crepidioides (Benth.) S.Moore) sebagai Nutrasetikal dalam Menunjang Derajat Kesehatan

Ni Kadek Hermiasih (2024)

Daun Sintrong (Crassocephalum crepidioides) dari famili Asteraceae merupakan salah satu contoh tumbuhan yang mungkin belum banyak dikenal masyarakat luas yang sering kali tumbuh sebagai semak belukar atau perdu di lingkungan tropis, sering diangg

23-06-2024
Potensi Aktivitas Hepatoprotektor dari Meniran (Phyllanthus niruri L.) pada Penderita Penyakit Hati

Ni Putu Rika Noviyanti (2024)

Penyakit hati bisa diakibatkan oleh sejumlah faktor diantaranya faktor genetik, infeksi virus, konsumsi alkohol, obesitas, bahan kimia, serta konsumsi obat-obatan. Setiap tahunnya, di wilayah Asia Tenggara, terjadi sekitar 410.000 kematian akibat

23-06-2024
Uji Aktivitas Antioksidan Kombinasi Ekstrak Daun Sambiloto dan Ekstrak Daun Pisang Batu Melalui Metode DPPH

I Made Gede Ari Kusuma (2024)

Fenomena perubahan frekuensi penyakit yang terjadi di negeri ini telah menciptakan pergeseran pola penyakit yakni adanya peningkatan penyakit degeneratif. Salah satunya penyebab terjadinya penyakit degeneratif adanya penumpukan radikal bebas di d

23-06-2024
Potensi Ekstrak Rimpang Jahe Merah (Zingiber officinale Rosc. var rubrum) Sebagai Nutraceutical

Ni Komang Diantari (2024)

Nutraceutical merupakan komponen atau zat baik berupa makanan ataupun bagian dari makanan yang bermanfaat bagi kesehatan manusia dalam hal ini termasuk pencegahan dan pengobatan penyakit. Jahe Merah (Zingiber officinale Rosc. var rubrum) merupaka

23-06-2024
Potensi Daun Salam (Syzygium polyanthum) Sebagai Antioksidan untuk Menangkal Radikal Bebas

I Gede Rheza Wisnu Bhadreswara (2024)

Dalam tubuh manusia, radikal bebas dapat berasal dari dua sumber. Radikal bebas yang bersumber dari luar tubuh seperti polusi udara, asap rokok dan radiasi dari perangkat elektronik seperti ponsel dan televisi. Radikal bebas dari dalam tubuh dapa

23-06-2024
Potensi Nutraceutical Sebagai Solusi Pencegahan Stunting

Gede Narendra Pramana Putra M (2024)

Stunting merupakan masalah pertumbuhan serta perkembangan pada anak-anak. Stunting terjadi akibat adanya kekurangan gizi sejak anak masih dalam kandungan ibu hingga bayi lahir, kekurangan gizi menyebabkan stunting. Balita stunting memiliki tinggi

23-06-2024
Aktivitas Antioksidan Alami dari Daun Dan Buah Mengkudu (Morinda Citrifolia L) Sebagai Penangkal Radikal Bebas

Ni Kadek Ayu Murtini (2024)

Radikal bebas yang ada dalam tubuh dapat dipicu oleh polutan dari lingkungan dan zat-zat yang terkandung dalam makanan yang tidak sehat. Ketidakseimbangan jumlah radikal bebas dalam tubuh dapat memicu stres oksidatif, yang pada akhirnya dapat men

23-06-2024
Review Artikel: Pengaruh Variasi Konsentrasi Bahan Pengikat Pada Formulasi Tablet Hisap Antibakteri Dari Bahan Alam Terhadap Sifat Fisik Sediaan

Ni Kadek Sri Wulan Adiari (2024)

Kesehatan rongga mulut memegang peranan penting, baik kualitas hidup maupun status gizi masyarakat. Pada Riset Kesehatan Dasar (Riskesdas) Republik Indonesia Tahun 2018, berbagai penyakit dapat muncul didalam mulut, sebanyak 57,6% masyarakat Indo

23-06-2024
Potensi Krim Biji Pinang (Areca catechu L.) sebagai Antibakteri Penyebab Jerawat

I Gede Ananta Wiguna (2024)

Penggunaan bahan alam dalam pengobatan saat ini sedang banyak digunakan dengan adanya istilah “Back to Nature” sehingga penggunaan bahan alam sebagai obat kembali menjadi primadona khususnya di Indonesia. Potensi pengembangan dan pengolahan

23-06-2024
Pemanfaatan Sereal Sorgum (Sorghum bicolor L.) Sebagai Imunonutrisi Dalam Upaya Meningkatkan Sistem Imun Tubuh

Ni Kadek Ida Rajeswari (2024)

Sistem imun adalah sistem yang membentuk kemampuan tubuh untuk menghalau bibit penyakit dengan menolak berbagai benda asing yang masuk ke dalam tubuh agar terhindar dari suatu penyakit. Banyak faktor yang mempengaruhi penurunan sistem imun, salah

23-06-2024
Pemanfaatan Teh Herbal Biji Jintan Hitam (Nigella sativa L.) Sebagai Agen Imunostimulan Pendamping Kemoterapi Doksorubisin Pada Pasien Kanker

I Putu Agus Saputra (2024)

Prevalensi kanker di Indonesia terbilang cukup tinggi yang mencapai 1,79 per 1000 penduduk dan akan terus meningkat setiap tahunnya. Kanker merupakan pertumbuhan sel tidak normal yang dapat menyerang jaringan tubuh lain bahkan menyebabkan kematia

23-06-2024
Efektivitas dan Toksisitas Daun Zaitun (Olea europaea L.) sebagai Nutrasetikal Penurun Tekanan Darah untuk Mengurangi Risiko Gagal Jantung

I Gusti Ayu Widha Paramistya Dewi (2024)

Gagal jantung merupakan salah satu penyakit kardiovaskular yang memiliki angka mortalitas yang tinggi di Indonesia. Gagal jantung terjadi ketika jantung tidak mampu menyediakan cukup darah ke seluruh tubuh yang ditandai dengan penurunan curah jan

23-06-2024
Potensi Berbagai Tanaman sebagai Nutrasetikal Diabetes Melitus dengan Mekanisme Kerja Menghambat Enzim ?-Glukosidase

Ni Komang Angelina Sinta Pratiwi (2024)

Diabetes melitus merupakan penyakit kronis yang didefinisikan oleh peningkatan kadar gula darah yang berkelanjutan, yang juga disertai dengan gangguan metabolisme karbohidrat, lipid, dan protein. Hal ini disebabkan oleh ketidakmampuan insulin dal

23-06-2024
Studi Literatur: Pengaruh Konsentrasi PVA dan HPMC Terhadap Sifat Fisik dan Stabilitas Fisik Masker Gel Peel-Off dari Bahan Alam

Ni Made Indah Maryani (2024)

Masker gel peel-off ialah salah satu produk kosmetika berupa gel dimana digunakan dengan cara dioleskan secara langsung ke kulit dan akan segera mengering. Dalam pembuatan masker gel peel-off terdapat beberapa komponen penting seperti PVA sebagai

23-06-2024
Review: Potensi Kandungan Fitokimia dan Aktivitas Binahong (Anredera cordifolia) sebagai Antibakteri

Ni Luh Diah Tantri (2024)

Binahong (Anredera cordifolia) merupakan salah satu tanaman obat yang umum ditemui di kalangan Masyarakat Indonesia. Binahong termasuk ke dalam famili basellaceae yang dikatakan mempunyai manfaat bagi kesehatan, khususnya sebagai aktivitas antiba

23-06-2024
Potensi Manfaat Kardioprotektif dari Asam Lemak Omega-3

Jeditya Shalom (2024)

Penyakit kardiovaskular merupakan penyebab kematian nomor satu di dunia. Asupan makanan memiliki peran yang besar dalam memelihara kesehatan dan pencegahan penyakit. Minyak ikan khususnya asam lemak omega-3 diketahui dapat memberikan efek kardiop

23-06-2024
Potensi Daun Kelor (Moringa oleifera L.) Pada Olahan Makanan Populer Sebagai Antioksidan Untuk Meningkatkan Nilai Gizi

Putu Ayu Sri Devi (2024)

Pada negara berkembang, olahan makanan populer yang terbuat dari sereal memiliki jumlah mikronutrien yang rendah dan kandungan protein yang buruk. Sereal pada umumnya dibuat dari bahan pokok yang popular yaitu tepung jagung. Penggilingan jagung m

23-06-2024
Review: Pengolahan dan Pengembangan Oat (Avena sativa L.) Menjadi Susu Nabati Rendah Lemak Bagi Penderita Hiperkolesterolemia

Luh Putu Laksmi Wiryani (2024)

Hiperkolesterolemia merupakan kondisi tingginya kadar kolesterol LDL (Low-density lipoprotein) di dalam darah atau dikenal dengan kolesterol tinggi. Penderita Hiperkolesterolemia harus menjaga makanan yang dikonsumsi agar kadar lemak di dalam dar

23-06-2024
Pengolahan dan Pengembangan Tanaman Herbal Tradisional Kunyit (Curcuma longa) Sebagai Masker Wajah Bagi Penderita Acne Vulgaris

A.A. Istri Agung Sri Chandrawati (2024)

Obat herbal merupakan obat tradisonal yang digunakan secara turun temurun. Manfaat yang dimiliki oleh kunyit tidak terbatas pada makanan dan minuman. Kandungan vitamin serta nutrisi yang terkandung pada kunyit diyakini bisa menyembuhkan berbagai

23-06-2024
Pengolahan dan Pengembangan Bawang Putih (Allium sativum L.) Menjadi Bawang Hitam sebagai Agen Antiaterosklerosis

Ni Kadek Dina Juniantari (2024)

Aterosklerosis merupakan penyakit inflamasi kronis pada dinding arteri yang disebabkan oleh penumpukan lemak dan disfungsi endotel di dinding arteri sehingga menyebabkan penyempitan pembuluh darah dan mengganggu aliran darah. Terjadinya peradanga

23-06-2024
Aktivitas Antibakteri Ekstrak Daun Tumpang Air (Peperomia pellucida) Sebagai Acne Gel Pencegah Jerawat

Gusti Ayu Putu Putri Kirana Dewi (2024)

Jerawat adalah salah satu masalah kulit yang banyak dikeluhkan oleh remaja. Jerawat umumnya diakibatkan oleh adanya produksi minyak berlebih yang kemudian akan menyumbat pori-pori wajah dan memicu adanya perkembangan bakteri sehingga terjadila

23-06-2024
Aktivitas Antibakteri Ekstrak Cengkeh (Syzygium aromaticum) sebagai Sediaan Pasta Gigi

Gusti Ayu Surya Ciptha Dewi (2024)

Karies gigi adalah penyakit yang dapat merusak struktur gigi akibat erosi dan degradasi enamel gigi. Karies gigi terjadi ketika sisa makanan dan bakteri dalam mulut berinteraksi dan membentuk asam yang akan merusak enamel gigi. Sehingga diperluka

23-06-2024
Potensi Pemanfaatan Nutrasetikal Daun Jintan (Coleus amboinicus Lour.) Sebagai Antioksidan

Lydia Devy Silalahi (2024)

Coleus amboinicus Lour. atau biasa disebut dengan daun jintan merupakan tanaman obat yang memiliki potensi yang besar dalam pengobatan berbagai macam penyakit. Hal ini disebabkan karena tanaman ini kaya akan senyawa aktif, seperti minyak atsiri,

23-06-2024
Potensi Tumbuhan Ginseng (Panax ginseng) sebagai Antioksidan untuk Menetralkan Radikal Bebas dalam Bentuk Nutrasetikal

Luh Putu Citramas Pradnya Rahmasari (2024)

Kesehatan menjadi penting agar daya tahan tubuh tidak mudah terserang penyakit. Pemanfaatan nutrasetikal untuk memelihara kesehatan menjadi salah satu bentuk hubungan manusia dengan lingkungan alamnya. Radikal bebas merupakan molekul yang memili

23-06-2024
Potensi Efek Terapeutik Suplementasi Melatonin Terhadap Perbaikan Penyakit Gagal Jantung

Ida Ayu Yadnyaningtias Permata Sari (2024)

Penyakit kardiovaskular menempati urutan tertinggi (35%) penyebab mortalitas di Indonesia dan mewakili 31% kematian global. Adapun salah satu penyakit kardiovaskular tersebut adalah gagal jantung. Gagal jantung dikenal sebagai sindrom klinis deng

23-06-2024
Potensi Antikanker Ekstrak Buah Jamblang (Syzygium cumini L.) sebagai Bahan Pangan Fungsional

Meivanti Diva Hapsari (2024)

Kanker merupakan suatu penyakit yang ditandai dengan terjadinya proliferasi sel-sel abnormal yang tidak terkendali. Berdasarkan data dari Global Cancer Statistics (GLOBOCAN) menunjukkan bahwa tahun 2020 terdapat jumlah kasus kanker sebanyak 19,3

23-06-2024
Potensi Kandungan Fitokimia Bawang Dayak (Eleutherine palmifolia (L.) Merr) sebagai Sumber Antioksidan

I Wayan Sindhu Wahyu Prasetya (2024)

Berdasarkan perbandingan data Riskesdas 2013 dengan Riskesdas 2018, prevalensi penyakit degeneratif mengalami peningkatan pada beberapa tahun terakhir. Salah satu faktor pemicu utama timbulnya penyakit ini yaitu adanya radikal bebas pada tubuh ma

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antimikroba Buah Alpukat (Persea americana Mill)

Armida Asya Farhani (2024)

Alpukat dengan nama spesies Persea americana Mill termasuk ke dalam family Lauraceae. Alpukat diketahui mampu berperan aktif sebagai agen antimikroba. Narrative review ini merupakan sebuah studi yang memiliki tujuan mengkaji penelitian-penelitian

23-06-2024
Potensi Tanaman Pinus dan Ekstraknya sebagai Penanganan Terapi pada Penyakit Diabetes dan Kardiovaskular

Dewi Purwani Caya Ningsih (2024)

Diabetes hingga kini menjadi ancaman dunia dan diestimasikan akan mencapai 9.5 miliar pada tahun 2024. Adapun penyumbang risiko kematian tertinggi pada pengidap diabetes salah satunya adalah komplikasi kardiovaskular. Studi ini bertujuan untuk m

23-06-2024
Potensi Fitoestrogen Semanggi Merah sebagai Nutraceutical untuk Mengatasi Sindrom Menopause

Ni Luh Putu Putri Dewi (2024)

Sindrom menoupause merupakan disfungsi seksual yang dialami oleh wanita pada akhir siklus menstruasi yang terjadi akibat penurunan kadar estrogen dalam darah. Oleh karena itu, diperlukan terapi penggantian hormon (Hormone Replacement Therapy) yan

23-06-2024
Potensi Pegagan (Centella asiatica) Sebagai Pengobatan Alzheimer

I Nyoman Gargita Ananta Guna (2024)

Pegagan (Centella asiatica (L.) adalah tumbuhan herba yang sering dijumpai tumbuh secara alami di berbagai lokasi. Pegagan tumbuh merayap tanpa batang dan memiliki daun tunggal yang membentuk roset akar, berwarna hijau dengan bentuk seperti kipas

23-06-2024
Pengaruh Konsentrasi Ekstrak Buah Naga (Hylocereus polyrhizus) Terhadap Sifat Fisik dan Stabilitas Sediaan Lipstick

Tri Bayu Prasatya Adnyana (2024)

Produk kosmetik banyak digunakan oleh semua kelompok umur masyarakat dengan tujuan untuk perawatan tubuh. Lipstick adalah salah satu produk dekorasi kosmetik yang paling sering digunakan. Lipstick, juga dikenal sebagai pewarna bibir merupakan pro

23-06-2024
Uji Kelarutan Flavonoid Ekstrak Kulit Salak Pondoh dalam Minyak, Surfaktan, dan Kosurfaktan untuk Preformulasi SNEDDS sebagai Nutrasetikal

Made Tresia Pramasta Diva (2024)

Kulit salak pondoh, yang biasanya dianggap sebagai limbah, mengandung flavonoid yang memiliki potensi antioksidan. Sifat antioksidan ini dimanfaatkan sebagai sediaan nutrasetikal untuk meningkatkan efektivitas terapi berbagai penyakit, yang difor

23-06-2024
Kajian Literatur: Aktivitas Ekstrak Etanol dari Tanaman Obat sebagai Peluruh Kalsium Batu Ginjal Secara In Vitro

Rifaldy Rahmadillah (2024)

Penyakit Batu Ginjal adalah masalah global yang mempengaruhi sekitar 12?ri populasi dunia. Prevalensi batu ginjal di Indonesia adalah sebanyak 6 per 1000 penduduk atau 1.499.400 penduduk Indonesia menderita batu ginjal. Beberapa tumbuhan di Indone

23-06-2024
Studi Literatur: Uji Aktivitas Antioksidan Ekstrak Jahe Merah (Zingiber officinale var. Rubrum) Menggunakan Metode 2,2- diphenyl-1-picrylhydrazyl (DPPH)

Khusnul Khatimah Rukhayyah (2024)

Jahe merah (Zingiber officinale var. Rubrum) merupakan tanaman rempah-rempah sekaligus tanaman yang berfungsi sebagai bahan baku obat-obatan. Dalam bidang kesehatan, jahe merah mengandung senyawa–senyawa yang bersifat antioksidan salah satunya

23-06-2024
Kajian Literatur Pengobatan Tuberkulosis Paru dan Efek Samping Obat Antituberkulosis di Indonesia

Andi Sri Wahyu Ningsih (2024)

Tuberkulosis (TB) merupakan masalah utama kesehatan global. TB disebabkan oleh Mycobacterium tuberculosis dan terutama menyerang organ paru-paru. Penggunaan obat antituberkulosis (OAT) menjadi hal utama dalam pengobatan tuberkulosis. Pengobatan y

23-06-2024
Kajian Literatur Pengobatan Tuberkulosis Paru dan Efek Samping Obat Antituberkulosis di Indonesia

Andi Sri Wahyu Ningsih (2024)

Tuberkulosis (TB) merupakan masalah utama kesehatan global. TB disebabkan oleh Mycobacterium tuberculosis dan terutama menyerang organ paru-paru. Penggunaan obat antituberkulosis (OAT) menjadi hal utama dalam pengobatan tuberkulosis. Pengobatan y

23-06-2024
Parameter Spesifik dan Non Spesifik Seduhan Herbal Celup Kelopak Bunga Rosella (Hibiscus Sabdariffa) dengan Penambahan Daun Pandan Wangi (Pandanus Amaryllifolius) dan Kayu Manis (Cinnamomum Burmanii)

Zuliayu Arizka Pratiwi (2024)

Seduhan Herbal Celup merupakan suatu sediaan yang sering digunakan sebagai obat tradisional oleh masyarakat dan sangat mudah untuk di konsumsi dalam bentuk herbal celup. Penelitian ini bertujuan untuk meningkatkan cita rasa dan mengetahui karakte

23-06-2024
Formulasi Sediaan Gel Handsanitizer Ekstrak Metanol Rumput Laut (Euchema spinosum) Asal Kota Bontang Kalimantan Timur

Zahra Praselya (2024)

Rumput Laut (Euchema Spinosum) merupakan tanaman yang memiliki aktivitas antioksidan dan antibakteri. Rumput Laut diketahui mengandung flavonoid, triterpenoid, steroid, dan alkaloid. Berdasarkan senyawa yang dimiliki rumput laut dapat dimanfaatka

23-06-2024
Formulasi Sediaan Gel Handsanitizer Ekstrak Metanol Rumput Laut (Euchema spinosum) Asal Kota Bontang Kalimantan Timur

Zahra Praselya (2024)

Rumput Laut (Euchema Spinosum) merupakan tanaman yang memiliki aktivitas antioksidan dan antibakteri. Rumput Laut diketahui mengandung flavonoid, triterpenoid, steroid, dan alkaloid. Berdasarkan senyawa yang dimiliki rumput laut dapat dimanfaatka

23-06-2024
Optimalisasi Induksi Hiperglikemik pada Zebrafish dan Skrining Fitokimia Infusa Daun Salam (Syzygium polyanthum) dengan Buah Belimbing Wuluh (Averrhoa bilimbi) sebagai Antidiebetes

Yusri (2024)

Salah satu penyakit degeneratif yaitu diabetes mellitus merupakan penyakit yang diakibatkan oleh kondisi kelebihan kadar glukosa darah atau hiperglikemik. Daun salam memiliki kandungan berupa senyawa flavonoid dan tanin yang diduga berkhasiat men

23-06-2024
Optimasi Basis Blush On Cream dengan Variasi Konsentrasi Asam Stearat

Yiska Priscilla Septilita (2024)

Blush on adalah kosmetika yang berfungsi untuk mewarnai pipi dengan sentuhan artistik sehingga dapat menciptakan kesan segar dalam tata rias wajah. Pada penelitian ini dipilih blush on cream dikarenakan mudah menyebar dan pengaplikasiannya lebih

23-06-2024
Studi Pengamatan Kepuasan Pasien Peserta BPJS Kesehatan terhadap Pelayanan Kefarmasian Unit Rawat Jalan RSUD Provinsi Sulawesi Barat

Wita Oileri Tikirik (2024)

RSUD Provinsi Sulawesi Barat merupakan rumah sakit milik pemerintah Provinsi Sulawesi Barat yang tugasnya memberikan pelayanan untuk pasien BPJS. Belum ada penelitian terkait kepuasan pasien BPJS rawat jalan terhadap pelayanan kefarmasian di unit

23-06-2024
Perbandingan Efektivitas Teh Daun Kecombrang (Etlingera elatior) dan Teh Bunga Kecombrang (Etlingera elatior) terhadap Penurunan Kadar Glukosa Darah pada Mencit (Mus musculus) yang Diinduksi Aloksan

Winchy Putri Cantika (2024)

Diabetes melitus merupakan suatu gangguan metabolik yang di karakterisasikan dengan terjadinya peningkatan kadar glukosa dalam darah. Kecombrang (Etlingera elatior) merupakan tanaman liar yang mudah dijumpai dan tersebar luas di Indonesia. Tanama

23-06-2024
Uji Aktivitas Antioksidan dari Sari Rebusan Daun Kersen (Muntingia calabura L.) dengan Metode DPPH (1,1-difenil-2-pikrilhidrasil)

Wahyu Trimadianti (2024)

Radikal bebas ikut serta dalam penyakit degeneratif seperti diabetes melitus, kerusakan hati, inflamasi, kanker, gangguan jantung, gangguan syaraf serta proses penuaan. Oleh karena itu, diperlukan antioksidan yang bisa membantu melindungi tubuh d

23-06-2024
Uji Aktivitas Antioksidan dari Sari Rebusan Daun Kersen (Muntingia calabura L.) dengan Metode DPPH (1,1-difenil-2-pikrilhidrasil)

Wahyu Trimadianti (2024)

Radikal bebas ikut serta dalam penyakit degeneratif seperti diabetes melitus, kerusakan hati, inflamasi, kanker, gangguan jantung, gangguan syaraf serta proses penuaan. Oleh karena itu, diperlukan antioksidan yang bisa membantu melindungi tubuh d

23-06-2024
Observasi Klinik Kombinasi Ekstrak Mentimun (Cucumis sativus L.) dan Labu Siam (Sechium edule) terhadap Tekanan Darah pada Pasien Hipertensi

Susan (2024)

Mentimun (Cucumis sativus L) dan labu siam (Sechium edule) ini mengandung kalium yang membantu dalam menurunkan tekanan darah. Penelitian ini bertujuan untuk mengetahui karakteristik responden meliputi usia, jenis kelamin, dan pekerjaan serta men

23-06-2024
Uji Antihiperlipidemia Ekstrak Etanol Bawang Batak (Allium chinense L.) pada Tikus Jantan Galur Wistar (Rattus norvegicus)

Seprinto Pranata Tamba (2024)

Hiperlipidemia merupakan suatu keadaan peningkatan kadar lemak yang terdapat dalam darah karena mengkonsumsi lemak secara berlebih (pada manusia >200mg/dl), sehingga asupan dan perombakan lemak tidak seimbang, hal ini ditandai dengan meningkatnya

23-06-2024
Review : Potensi Ekstrak Kopi Robusta dengan Metode Pengeringan Freeze Drying dalam Formulasi Masker Gel Peel-Off

Gusti Ayu Dian Ratna Dewi (2024)

Penuaan kulit merupakan salah satu permasalahan yang sering dijumpai di masyarakat. Sehingga diperlukan suatu agen anti photoaging yang dapat mengurangi atau menghambat proses degeneratif tersebut. Salah satu bahan alam yang berpotensi sebagai ag

23-06-2024
Skrining Fitokimia dan Uji Aktivitas Antioksidan Ekstrak Etanol Kulit Jeruk Nipis (Citrus aurantifolia) Menggunakan Metode DPPH

Ririn Novriyanti (2024)

Citrus aurantifolia adalah sejenis tanaman perdu yang banyak tumbuh dan dikembangkan di Indonesia. Jeruk nipis juga merupakan salah satu tanaman toga yang di gunakan oleh masyarakat, baik untuk bumbu masakan, obat-obatan, dan minuman segar. Tujua

23-06-2024
Potensi Daun Kelor (Moringa oleifera) Sebagai Antibakteri Pada Sediaan Gel Untuk Mengatasi Jerawat

I Gede Ngurah Aldiantara Merta (2024)

Jerawat merupakan salah satu permasalahan kulit wajah yang paling sering terjadi terutama dikalangan remaja, jerawat umumnya disebabkan karena adanya infeksi bakteri. Pengobatan dengan bahan alami seperti tanaman adalah alternatif yang lebih aman

23-06-2024
Potensi Ekstrak Daun Kersen (Muntingia Calabura L.) Sebagai Bahan Aktif Formulasi Masker Peel-Off Antioksidan

I Made Saka Palguna (2024)

Kulit menjadi lapisan pelindung terluar tubuh dari paparan polusi lingkungan, khususnya kulit wajah yang terpapar langsung oleh sinar ultraviolet (UV). Paparan radikal bebas dari lingkungan memicu pembentukan radikal bebas yang disebut juga react

23-06-2024
Evaluasi Kejadian Ikutan Pasca Imunisasi pada Peserta Vaksinasi di Puskesmas Teluk Dalam, Tenggarong Seberang

Renaldi Adi Saputra (2024)

Kejadian Ikutan Pasca Imunisasi (KIPI) merupakan suatu kejadian yang tidak diharapkan pada saat proses imunisasi. KIPI dari berbagai jenis vaksin memiliki efek yang beragam mulai dari yang ringan hingga berat. KIPI pada vaksin COVID-19 berpengaru

23-06-2024
Review : Studi Formulasi dan Evaluasi Lulur Ampas Kopi Robusta

Putu Elsabella Putri Utami (2024)

Kopi robusta merupakan salah satu produk kopi yang dibudidayakan dan dikonsumsi oleh masyarakat Indonesia selain kopi arabika. Kopi juga telah dimanfaatkan menjadi berbagai produk kosmetik salah satunya lulur atau scrub. Tujuan review artikel ini

23-06-2024
Identifikasi Metabolit Sekunder dan Toksisitas Ekstrak Daun Putri Malu (Mimosa Pudica Linn.)

Putri Purnamasari (2024)

Daun putri malu (Mimosa pudica Linn.) merupakan salah satu tanaman yang jarang diketahui manfaatnya dan berkesan sebagai tanaman liar. Daun putri malu merupakan tanaman yang memiliki ciri khusus daun yang menutup dengan sendirinya saat disentuh d

23-06-2024
Optimasi Metode MAE terhadap Kadar Polifenol dan Profil KLT dari Rimpang Jahe Merah (Zingiber officinale)

Nursya’bani Bismar Nugraha (2024)

Penelitian ini bertujuan untuk mengetahui kondisi optimum kadar polifenol dari rimpang jahe merah (Zingiber officinale var. rubrum rhizoma) yang diekstraksi menggunakan metode MAE dengan variabel: waktu (menit), rasio padat-cair (ml/g) dan power

23-06-2024
Evaluasi Penggunaan Obat pada Pasien Diabetes Melitus dengan Komplikasi Stroke di RSUD Aji Muhammad Parikesit Tenggarong Tahun 2020

Nuraisyah (2024)

Diabetes mellitus mampu menebalkan dinding pembuluh darah otak yang akan menimbulkan aterosklerosis dan menghambat aliran darah ke otak akhirnya dapat menyebabkan kematiaan sel-sel otak dan mengakibatkan stroke. Hiperglikemia menyebabkan kerusaka

23-06-2024
Aktivitas Antibakteri Ekstrak Daun Kemangi sebagai Hand Sanitizer Ramah Lingkungan

Ni Putu Eva Citra Darmaputri (2024)

Prilaku hidup bersih dan sehat dengan slogan “back to nature” sedang menjadi populer di kalangan masyarakat global. Salah satu cara paling efektif untuk menjaga kebersihan dilingkungan luar adalah dengan menggunakan hand sanitizer. Kebanyakan

23-06-2024
Pengaruh Jenis Pelarut terhadap Aktivitas Antibakteri Penyebab Jerawat dari Ekstrak Daun Kelapa Sawit (Elaeis Guineensis Jacq.)

Nur Aini (2024)

Jerawat merupakan masalah umum yang terjadi pada populasi manusia di dunia yang disebabkan oleh bakteri penyebab jerawat seperti Propionibacterium acne. Pemanfaatan limbah dari bahan alam seperti daun kelapa sawit yang memiliki kandungan senyawa

23-06-2024
Potensi Ekstrak Daun Jambu Biji (Psidium guajava) terhadap Penghambatan Staphylococcus aureus Penyebab Ketombe sebagai Bahan Aktif Sampo

I Made Hary Purnawan (2024)

Ketombe merupakan pengelupasan kulit kepala secara berlebihan, berbentuk seperti sisik-sisik disertai dengan adanya kotoran berlemak, rambut rontok, serta rasa gatal. Masalah ketombe dipicu salah satunya oleh keberadaan bakteri Staphylococcus aur

23-06-2024
Potensi Galangin Pada Rimpang Lengkuas sebagai Anti-Photoaging dengan Metode Molecular Docking

Ketut Yuantarisa Kartika Putri (2024)

Photoaging adalah penuaan pada kulit yang disebabkan oleh paparan sinar ultraviolet. Indonesia merupakan negara tropis yang mendapatkan paparan sinar matahari sepanjang tahun. Kondisi tersebut mengakibatkan masyarakatnya rentan untuk mengalami ph

23-06-2024
Optimasi Formula Sediaan Krim Ekstrak Kulit Putih Buah Semangka (Citrullus lanatus (Thunb.) Matsum & Nakai) sebagai Antijerawat

Ni Made Mela Santi (2024)

Kulit putih buah semangka merupakan bahan alam yang memiliki potensi sebagai antibakteri dan dapat diolah kembali menjadi produk untuk perawatan kulit wajah seperti krim. Penelitian ini dilakukan untuk mengetahui konsentrasi terbaik dari basis kr

23-06-2024
Review: Aktivitas Antioksidan Buah Naga dengan Metode DPPH serta Potensinya Sebagai Tabir Surya

Ni Made Udayani Dwi Yadnya (2024)

Antioksidan merupakan senyawa yang dapat melawan radikal bebas di dalam tubuh. Antioksidan membantu mencegah penyakit kronis dan degeneratif. Tujuan dari artikel review ini untuk mengumpulkan informasi tentang tanaman dengan aktivitas antioksidan

23-06-2024
Formulasi Sediaan Krim Antioksidan Ekstrak Etanol Kulit Pisang Kepok (Musa acuminata Colla)

Natalia Rara Samban (2024)

Kulit pisang kepok memiliki kandungan senyawa alkaloid, saponin, flavonoid, dan tannin yang memiliki potensial antioksidan. Penelitian ini bertujuan untuk menguji aktivitas antioksidan dari ekstrak etanol kulit pisang kepok dan menguji aktivitas

23-06-2024
Studi Potensi Senyawa Hidrangenol dan Asam Hidrangeat dari Daun Hydrangea macrophylla sebagai Bahan Utama Aktif Khasiat Jamu Antidiabetes

Ayu Pradnya Paramita (2024)

Diabetes mellitus merupakan salah satu penyakit metabolik yang menyebabkan tingginya angka mortalitas di dunia dan di Indonesia secara khususnya. Terapi farmakologi yang dilakukan untuk penyakit diabetes mellitus selama ini umumnya menggunakan ob

23-06-2024
Potensi Ekstrak Kulit Buah Manggis dalam Sediaan Salep sebagai Pengobatan Topikal terhadap Bakteri Penyebab Bisul

I Kadek Avryo Artanugraha (2024)

Penyakit kulit salah satunya yaitu infeksi kulit dapat terjadi dikarenakan luka kecil atau goresan pada kulit, bila banyak bakteri pada permukaan kulit seperti Staphylococcus aureus dapat mengakibatkan infeksi pada folikel rambut dan kelenjar ker

23-06-2024
Kualitas Hidup Pasien Diabetes Melitus Tipe 2 di RSUD Sultan Syarif Mohamad Alkadrie Pontianak

Muhammad Akib Yuswar (2024)

Diabetes Melitus tipe 2 (DM tipe 2) merupakan penyakit seumur hidup dimana tubuh tidak mampu memproduksi atau menggunakan insulin dengan cara yang benar. Orang dengan DM tipe 2 dikatakan memiliki resistensi insulin. Komplikasi yang tidak segera d

23-06-2024
Potensi Antijerawat Ekstrak Daun Paku Sarang Burung (Asplenium nidus L.) dalam Formulasi Nanoemulgel

A. A. Sagung Indah Candra Putri (2024)

Kulit merupakan organ yang berfungsi melindungi tubuh manusia dari pengaruh lingkungan. Jerawat atau Acne vulgaris merupakan kelainan kulit kronis yang melibatkan folikel rambut dan kelenjar sebaseus. Salah satu penyebab jerawat adalah kolonisasi

23-06-2024
Identifikasi Metabolit Sekunder Air Seduhan Daun Kelor (Moringa oleifera Lam.) dan Bawang Dayak (Sisyrinchium palmifolium L.) yang Berpotensi sebagai Inhibitor ?-Glukosidase

M. Khalid Akbar (2024)

Ekstrak air daun kelor (Moringa oleifera Lam) dan bawang dayak (Sisyrinchium palmifolium L.) mengandung metabolit sekunder yaitu alkaloid, flavonoid, saponin, steroid, tanin, dan kuinon. Metabolit sekunder seperti alkaloid, flavonoid, saponin, st

23-06-2024
Skrining Senyawa Aloesin Pada Lidah Buaya (Aloe vera (L.) Burm.f.) sebagai Antikanker Prostat Secara In Silico

Ni Luh Putu Cintya Pramesti (2024)

Kanker prostat merupakan tumor ganas yang menempati urutan kelima jumlah penderita terbanyak pada pria di Indonesial. Salah satu penyebab terjadinya kanker prostat yaitu adanya ekspresi berlebih dari reseptor androgen yang meregulasi poliferasi s

23-06-2024
Observasi Klinik Penggunaan Madu dan Ekstrak Labu Siam (Sechium Edule) sebagai Antihipertensi

Kiki Nur Azizah Hidayatul Fitria (2024)

Madu dan buah labu siam (Sechium edule) merupakan salah satu bahan alam yang memiliki aktivitas antihipertensi. Kandungan bahan aktif flavonoid, alkaloid, saponin, tanin serta tinggi kalium dalam madu dan buah labu siam memiliki efek sinergis dal

23-06-2024
Aktivitas Farmakologi Jamur Endofit Tanaman Suku Zingiberaceae Sebagai Kandidat Produk Kosmetik Hijau

Caresya Insani Bangga Nabila (2024)

Kosmetik hijau adalah kosmetik yang terbuat dari bahan alami, tanpa pewarna atau pengawet buatan, dan lebih ramah lingkungan. Konsumen yang sadar kesehatan akan memilih produk kosmetik hijau karena tidak mengandung bahan yang dapat membahayakan t

23-06-2024
Profil Pengobatan dan Hasil BTA Pada Pasien Tuberkulosis Paru di RSUD Abdul Wahab Sjahranie Samarinda

Jihan Huwaida Noor Santung (2024)

Tuberkulosis merupakan salah satu penyakit yang disebabkan oleh infeksi bakteri Mycobacterium tuberculosis yang menyerang organ lain terutama paru paru. Keberhasilan pada pengobatan tuberkulosis sangatlah penting untuk mengurangi resiko penularan

23-06-2024
Potensi Niosom Ekstrak Green Coffee Beans sebagai Serum Wajah Antioksidan

I Made Wahyu Surya Permana (2024)

Paparan sinar UV berlebih pada kulit menyebabkan kerusakan foto-oksidatif melalui penghasilan reactive oxygen species dalam bentuk oksigen singlet, radikal superoksida dan radikal peroksida yang memicu sunburn, penuaan dini, fotodermatosis, psor

23-06-2024
Optimasi Konsentrasi Basis HPMC Sediaan Sampo Antiketombe Ekstrak Daun Belimbing Wuluh (Averrhoa bilimbi L.) Kombinasi Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb)

Herlita Gasella Salsabila (2024)

Daun belimbing wuluh memiliki kandungan senyawa flavonoid, saponin, sulfur, asam format, peroksida, dan steroid dengan aktivitas anti kapang dan khamir pada Candida albicans. Daun pandan wangi dapat menghambat pertumbuhan Candida albicans karena

23-06-2024
Potensi Teh Herbal Herba Suruhan sebagai Anti Hipertensi Melalui Aktivitas Penghambatan Angiotensin-Converting Enzyme (ACE)

Ni Made Wuni Anamaptani (2024)

Prevalensi penderita hipertensi pada tahun 2018 di Indonesia mencapai 34,1?n terus meningkat setiap tahunnya. Hipertensi ditandai dengan pembacaan tekanan darah sistolik yang melebihi nilai 140 mmHg dan tekanan darah diastolik melebihi nilai 90 m

23-06-2024
Optimasi Basis Carbopol dan Uji Fisik Basis Gel Anti Jerawat

Helga Lisu Sarira (2024)

Indonesia mempunyai keanekaragaman hayati dimana terdapat sekitar 70,000 jenis tumbuhan dan 7,000 diantaranya merupakan tumbuhan obat. Namun pemanfaatan tanaman dalam bentuk formula siap pakai masih sangat kurang, kebanyakan penggunaan tanaman ob

23-06-2024
Potensi Serum Liposom Ekstrak Biji Kopi Arabika (Coffea arabica L.) Sebagai Antioksidan

Diah Mawarni Fitriari (2024)

Kopi arabika mengandung kafein, polisakarida, trigliserida, asam klorogenat, dan asam lemak linoleate. Kandungan dari asam linoleate memiliki sekitar 40-45% yang berfungsi untuk melembabkan kulit dan meremajakan kulit. Ekstrak biji kopi arabika

23-06-2024
Optimasi Basis Footspray Sebagai Alternatif Bahan Dasar Antibakteri Kaki

Hawanda Nur Afifah (2024)

Bagian tubuh yang paling banyak memproduksi keringat adalah kaki. Hal ini bisa membuat kuman mudah berkembang biak dan menyebabkan bau kaki yang dapat mengganggu kepercayaan diri seseorang. Ada beberapa cara untuk menghilangkan permasalahan pada

23-06-2024
Review Artikel: Aktivitas Antioksidan Formulasi Sediaan Krim dari Berbagai Tanaman

Komang Tri Wahyu Widiantari (2024)

Sediaan krim adalah salah satu sediaan farmasi yang memiliki tekstur setengah padat yang dialamnya mengandung bahan obat yang terdispersi serta terlarut pada bahan pelarut yang sesuai. Paparan sinar UV pada kulit mampu menyebabkan hiperpigmentasi

23-06-2024
Identifikasi Potensi Peresepan Obat Tidak Tepat pada Pasien Geriatri dengan Penyakit Kardiovaskular Berdasarkan Kriteria STOPP START di Salah Satu Rumah Sakit Balikpapan

Hanifah Hibattulwafi (2024)

Geriatri cendrung memiliki lebih dari satu penyakit yang menyebabkan pemberian resep polifarmasi. Polifarmasi merupakan faktor terjadinya peresepan obat tidak tepat. Kriteria STOPP START dapat digunakan untuk mengidentifikasi peresepan obat yang

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antibakteri Nagasari (Mesua ferrea) yang Berpotensi Digunakan sebagai Toner Wajah

Ni Made Marisa Kumala Sari (2024)

Pemanfaatan sumber daya lokal merupakan langkah yang tepat untuk dapat membantu kehidupan dibandingkan dengan obat dari bahan sintetik. Pemanfaatan sumber daya lokal yang dapat digunakan salah satunya adalah untuk produk kecantikan. Produk kecan

23-06-2024
Analisis Kandungan Zat Gizi Makro Cookies Kombinasi Tepung Daun Kelor (Moringa oleifera L.) dan Tepung Ubi Jalar Ungu (Ipomea batatas L.)

Fitriani Miranda (2024)

Cookies merupakan salah satu jenis kue kering yang banyak dikonsumsi oleh masyarakat mulai dari kalangan anak-anak hingga dewasa. Cookies seringkali dikonsumsi sebagai makanan selingan untuk menyumbangkan energi dan sebagai pengganti energi yang

23-06-2024
Review: SNEDDS Gel Kombinasi Ekstrak Daun Pegagan dan Daun Sirih Merah Sebagai Agen Penyembuh Luka

Ni Putu Intan Satya Dewi (2024)

Luka adalah keadaan terjadi putusnya jaringan tubuh yang menyebabkan fungsi tubuh terganggu dalam melakukan aktivitas. Luka apabila tidak diobati sesuai dengan pengobatan yang benar, maka rentan menyebabkan waktu penyembuhan luka menjadi lama. Ek

23-06-2024
Uji Aktivitas Penghambatan Radikal Bebas DPPH dari Ekstrak Etil Asetat Batang Penara (Myristica Iners Blume.)

Faizah Hanan Lestari (2024)

Tumbuhan penara (Myristica iners Blume) merupakan tumbuhan asli dari Indonesia yang termasuk marga dari Myristica. Informasi ilmiah mengenai tumbuhan penara belum banyak diketahui dan masih terbatas penelitian tentang aktivitas antiradikal bebas t

23-06-2024
Pemanfaatan Tanaman Herbal Dalam Pengobatan Nyeri Berdasarkan Kearifan Lokal Bali Usada Tiwang

Ni Kd Rintan Listiani Ekayanti (2024)

Nyeri merupakan rasa tidak nyaman yang umumnya merupakan tanda adanya gangguan fungsi organ atau kerusakan pada organ tubuh seperti peradangan, infeksi kuman, atau kejang otot. Analgesik sintetik merupakan terapi yang paling umum digunakan untuk

23-06-2024
Standarisasi Mutu Sediaan Rebusan Ramuan Herbal Kunyit (Curcuma longa), Daun Kelor (Moringa aloifera), Gula Aren, dan Madu Kelulut

Fairuzzainab Fahriyah (2024)

Standarisasi mutu suatu sediaan herbal penting untuk merupakan komponen terpenting yang wajib dilakukan untuk menjaga kualitas sediaan rebusan rimpang kunyit, daunkelor, gula aren dan madu kelulut berdasarkan persyaratan yang berlaku. Standarisas

23-06-2024
Pemanfaatan Yoghurt Sebagai Masker Alami Untuk Meningkatkan Kesehatan Dan Kecantikan Kulit Wajah

Luciana Octavia Selvi Correia (2024)

Masker wajah merupakan kosmetik perawatan kulit wajah yang sangat bermanfaat untuk menjaga dan merawat wajah, mengelastisitas kulit, mencegah penuaan dini serta munculnya keriput. Saat ini penggunaan kosmetik yang ramah lingkungan dengan memanfaa

23-06-2024
Review : Potensi Tanaman Alpukat (Persea americana) Sebagai Zat Aktif dalam Formulasi Sediaan Krim Anti Jerawat

Annisa Noviyani (2024)

Kosmetik kini sudah menjadi kebutuhan utama sehari-hari, terutama bagi perempuan. Namun tidak semua kosmetik aman untuk kesehatan individu maupun lingkungan. Sediaan krim adalah salah satu jenis kosmetik yang populer digunakan oleh masyarakat. Kr

23-06-2024
Skrinning Fitokimia Ekstrak Etanol Kulit Pisang Kepok (Musa paradisiaca L.) dan Evaluasi Sediaan Krim Wajah

Ester Melenya Looys Nababan (2024)

Kulit pisang kepok (Musa paradisiaca L.) dimanfaatkan secara nyata, hanya dianggap sebagai limbah organik saja atau hanya sebatas digunakan sebagai pakan ternak. Sehingga pada penelitian ini dilakukan skrinning fitokimia untuk mengetahui senyawa

23-06-2024
Potensi Buah Semangka (Citrullus lanatus) Sebagai Bahan Aktif Sediaan Hair Tonic Alami: Literatur Review

Izzul Ishfahan (2024)

Hair tonic adalah sejenis kosmetik perawatan rambut yang memiliki efek mengurangi kerontokan rambut, merangsang dan meningkatkan volume rambut. Bahan aktif yang digunakan dapat berupa bahan kimia sintetik atau berasal dari tumbuhan atau diekstrak

23-06-2024
Formulasi Sediaan Krim Body scrub dari Serbuk Kopi yang Dikombinasikan dengan Minyak Zaitun sebagai Pencerah dan Pelembab Kulit

Elit Dita Paradila (2024)

Body scrub merupakan produk kecantikan yang bekerja untuk membersihkan kotoran pada sel kulit mati hingga mencegah terjadinya kerusakan kulit. Kopi memiliki kandungan-kandungan yang baik untuk kulit seperti zat antioksidan yang cukup tinggi diant

23-06-2024
Potensi Daun Zodia (Evodia Suaveolens) Sebagai Biolarvasida yang Mampu Menghambat Perkembangan Nyamuk Aedes agypti

Ni Putu Shinta Paramita Sari (2024)

Penyakit Menular Demam Berdarah Dengue (DBD) merupakan salah satu penyakit yang rentan terjadi di masyarakat. Virus dengue ditularkan melalui gigitan nyamuk Aedes aegypti dan merupakan vektor utamanya. Salah satu cara pencegahannya adalah penggun

23-06-2024
Aktivitas Antimikroba Ekstrak Buah Mahkota Dewa (Phaleria macrocarpa) sebagai Hand Sanitizer Alami

Ayu Charina Mahayuni TK. (2024)

Hand sanitzer yang mengandung alkohol dosis tinggi dan frekuensi penggunaan yang tinggi sebagai pembersih tangan dapat menyebabkan infeksi dan iritasi kulit. Oleh karena itu, diperlukan hand sanitizer yang terbuat dari alam atau mengandung bahan-

23-06-2024
Sifat Fisika Kimia Tulang Sotong (Sepia Sp.) dan Optimasi Basis Pasta Gigi

Dyah Ayu Puspo Rini (2024)

Limbah Tulang Sotong (Sepia Sp.) memiliki kandungan kalsium karbonat (CaCO3) yang selama ini belum optimal pemanfaatannya. Penelitian ini bertujuan untuk mengetahui basis terbaik dari tiga seri formulasi dengan Variasi F1, F2 dan F3, serta karakt

23-06-2024
Potensi Kombinasi Akar Manis (Glycyrrhiza glabra) dan Propolis dalam Bentuk Sediaan Tablet Effervescent sebagai Imunomodulator

G.A. Desya Pradnyaswari (2024)

Munculnya sebuah penyakit yaitu Coronavirus disease 2019 atau disebut juga dengan COVID 19 telah berhasil menggemparkan dunia. Upaya pencegahan terhadap COVID-19 adalah dengan meningkatkan imunitas atau sistem kekebalan tubuh. Dalam upaya peningka

23-06-2024
Pola Penggunaan Antibiotik pada Pasien Bedah Apendiktomi Berdasarkan ATC/DDD di RSUD Kanujoso Djatiwibowo Balikpapan

Dhea Annisa Putri (2024)

Apendisitis merupakan peradangan yang terjadi pada apendiks vermiformis atau yang dikenal sebagai usus buntu. Penatalaksanaan apendisitis dilakukan dengan apendiktomi yang merupakan operasi bersih kontaminasi, sehingga perlu dilakukan pemberian a

23-06-2024
Potensi Nanostructured Lipid Carrier (NLC) dengan Zat Aktif Ekstrak Herba Pegagan (Centella asiatica (L.) Urb.) sebagai Sediaan Topical Gel Anti-photoaging

Komang Dian Aditya Putra (2024)

Paparan sinar UVB berlebih pada kulit akan menstimulasi produksi ROS yang bertanggung jawab dalam stres oksidatif pada kulit dengan merusak serat jaringan ikat sehingga menimbulkan manifestasi klinis berupa kerutan yang kerap disebut sebagai phot

23-06-2024
Formulasi dan Optimasi Basis Serum Xanthan Gum dengan Variasi Konsentrasi

Chairunnisa Aprilia (2024)

Serum merupakan sediaan topikal dengan viskositas yang lebih rendah dan warna semi transparan hingga transparan. Xanthan gum befungsi sebagai pengental dengan sifat yang stabil pada pH dan suhu yang luas. Penelitian ini bertujuan untuk mengetahui

23-06-2024
Potensi Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb) Sebagai Antibakteri Pada Sediaan Gel Facial Wash

Gek Niken Tasya Lingling (2024)

Jerawat (acne) adalah penyakit pada permukaan kulit yang berkaitan dengan produksi kelenjar minyak (sebum) berlebih. Jerawat dapat terjadi karena tersumbatnya folikel polisebase yang disebabkan oleh infeksi bakteri, seperti Staphylococcus epiderm

23-06-2024
Formulasi Masker Clay Ekstrak Kelopak Bunga Rosella (Hibiscus sabdariffa L.) sebagai Antioksidan

Ardella Safilla (2024)

Rosella (Hibiscus sabdariffa L.) diketahui memiliki banyak senyawa aktif yang berfungsi sebagai antioksidan seperti flavonoid, polifenol, antosianin, dan vitamin C. Penelitian ini bertujuan untuk membuat sediaan masker clay ekstrak kelopak bunga

23-06-2024
Studi Potensi Senyawa Hesperidin dan Naringin Kulit Jeruk Nipis (Citrus aurantifolia) sebagai Agen Antiphotoaging secara In Silico

Ni Made Rita Wiantini (2024)

Indonesia merupakanonegara tropis dengan paparan sinar matahariosepanjang tahun yang menyebabkan pendudukoIndonesiaorentan mengalami photaging. Photoaging merupakan kondisi penuaanokulit yang disebabkan karena paparan sinar ultraviolet (UV) berle

23-06-2024
Formulasi Sediaan Gel Masker Wajah Peel-Off dari Ekstrak Daun Melati (Jasminum Sambac L.) Sebagai Antibakteri Penyebab Jerawat

Andi Berbi Ollan Yunus (2024)

Jasminum sambac L merupakan tanaman yang memiliki aktivitas sebagai antibakteri. Tujuan dari penelitian ini adalah membuat formulasi sediaan gel masker wajah peel-off dari ekstrak daun melati (Jasminum sambac L) sebagai antibakteri penyebab jeraw

23-06-2024
Review: Studi Kandungan Fitokimia, Aktivitas Antibakteri dan, Toksisitas Karamunting (Melastoma malabathricum L.)

Luhde Manik Sugiantina (2024)

Karamunting (Melastoma malabatchricum L.) mempunyai manfaat bagi kesehatan, diantaranya sebagaii aktivitas antibakteri. Artikel ini disusun guna memberikan informasi tentang kandungan fitokimia, aktivitas antibakteri, dan toksisitas dari karamunt

23-06-2024
Potensi Ekstrak Daun Ubi Jalar (Ipomoea batatas L.) sebagai Suplemen Penurun Gula Darah

Wahyu Nadi Eka Putri (2024)

Diabetes melitus (DM) adalah suatu sindrom klinis gangguan metabolisme yang dikarakterisasi dengan tingginya kadar gula dalam darah (hiperglikemia) yan g diakibatkan oleh salah satu atau kombinasi dua faktor utama yakni defisiensi sekresi insulin

23-06-2024
Aktivitas Antioksidan Teh Herbal Daun Kelor (Moringa oleifera) dan Teh Herbal Bawang Dayak (Eleutherine americana)

Amalia Srikurniawati (2024)

Daun kelor dan bawang dayak memiliki kandungan senyawa flavonoid yang dapat berfungsi sebagai antioksidan. Saat ini pengkonsumsian minuman herbal yang banyak dikonsumsi masyarakat adalah minuman dalam bentuk teh herbal. Tujuan penelitian ini yait

23-06-2024
Potensi Amorphophallus sp. sebagai Pangan Fungsional untuk Pasien Diabetes Melitus

Fiorenza Jocelyn Thelmalina (2024)

Diabetes Melitus termasuk penyakit metabolik yang dikenal dengan ketidakmampuan sel tubuh dalam menggunakan insulin hasil produksi pankreas secara efisien untuk mengubah glukosa menjadi energi. Diabetes Melitus dapat disebut sebagai the silent ki

23-06-2024
Evaluasi Ketepatan Penggunaan Obat pada Pasien Lupus Eritematosus Sistemik (LES) di RSUD Kanujoso Djatiwibowo Kota Balikpapan Tahun 2020-2021

Alida Adelia Islami (2024)

Lupus Eritematosus Sistemik (LES) merupakan penyakit autoimun yang bersifat kronis dan sistemik ditandai dengan produksi antibodi yang berlebih sehingga menimbulkan berbagai manifestasi klinis pada organ tubuh. Penelitian ini bertujuan untuk meng

23-06-2024
Potensi Biji Kopi Hijau (Green Bean Coffee) Sebagai Suplemen Penurun Berat Badan

Ni Luh Wayan Sita Pujasari (2024)

Obesitas adalah penyakit yang bersifat multifaktorial terjadi akibat ketidakseimbangan asupan kalori dengan pengeluaran energi sehingga terjadi akumulasi berlebihan jaringan adiposa atau lemak yang dapat mengganggu kesehatan. Pasien diklasifikasi

23-06-2024
Studi Literatur Kandungan Fitokimia, Aktivitas Farmakologi, dan Toksisitas Cempedak (Artocarpus integer (Thunb.) Merr.)

Ni Made Mirah Satya Kanti (2024)

Cempedak (Artocarpus integer) dari famili Moraceae cukup dikenal oleh masyarakat Indonesia. Buah ini satu famili dengan buah nangka, sehingga memiliki penampilan mirip dengan buah nangka namun tekstur buahnya berbeda. Tanaman ini dilaporkan terbu

23-06-2024
Efektivitas Pemberian Kombinasi Jus Jambu Biji Merah (Psidium guajava L.) dan Lemon (Citrus limon L.) untuk Meningkatkan Kadar Hb pada Wanita Menstruasi

Alia Nur (2024)

Menstruasi merupakan proses keluarnya darah secara teratur dan bersiklus, yang terjadi ketika dinding lapisan terdalam dari rahim (endometrium) luruh. Jambu biji merah dan lemon merupakan salah satu sumber buah yang dapat meningkatkan kadar hemog

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antimikroba Kecombrang (Etlingera elatior)

Ni Putu Gayatri Dewi Dasi (2024)

Kecombrang (Etlingera elatior) merupakan tanaman yang telah banyak digunakan untuk pangan dan pengobatan tradisional. Tanaman ini termasuk ke dalam famili zingiberaceae yang diketahui mengandung berbagai metabolit sekunder yang berpotensi sebagai

23-06-2024
Potensi Tumbuhan Tampoi (Baccaurea macrocarpa) sebagai Antioksidan

Meliyana Dwi Pangesti (2024)

Radikal bebas merupakan molekul yang memiliki elektron yang tidak berpasangan pada orbital luarnya sehingga menjadi sangat reaktif dan tidak stabil. Radikal bebas dapat memicu berbagai penyakit degeneratif. Tumbuhan tampoi (Baccaurea macrocarpa)

23-06-2024
Potensi dan Aktivitas Antibakteri Madu, Bee Pollen, dan Propolis dari Lebah Kele (Trigona sp.) terhadap Bakteri Penyebab Jerawat

Sang Ayu Made Dwi Ariesta Putri (2024)

Jerawat merupakan peradangan yang terjadi di bagian tubuh seperti wajah, dada, leher, dan punggung yang lumrah dialami pada usia remaja hingga dewasa. Jerawat dikarakterisasi dengan adanya papula, komedo hitam dan putih, pustula, nodul, dan jeraw

23-06-2024
Potensi Isokuersitrin Sebagai Agen Antihiperpigmentasi Secara In Silico Dengan Metode Molecular Docking

Ni Luh Ari Krisma Anjani (2024)

Prevalensi hiperpigmentasi di Asia cukup tinggi, salah satunya di Indonesia. Iklim tropis Indonesia dan pajanan sinar matahari yang intens berdampak pada peningkatan kejadian hiperpigmentasi. Hiperpigmentasi merupakan peningkatan produksi melanin

23-06-2024
Formulasi Sediaan Gel Totol Jerawat Berbahan Aktif Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus) terhadap Bakteri Staphylococcus aureus dan Propionibacterium acnes

Absharina Qisthi Azhari (2024)

Kulit buah naga (Hylocereus polyrhizus) berpotensi sebagai antibakteri yang dapat diformulasi sebagai sediaan gel totol jerawat. Gel totol jerawat berbahan aktif ekstrak kulit buah naga dievaluasi meliputi olganoleptik, homogenitas, pH, daya seba

23-06-2024
Efek Penambahan Minyak Jahe Sebagai Antioksidan Alami Dalam Mempertahankan Stabilitas Minyak Ikan Patin (Pangasius hypophthalmus)

Yan Hendrika (2024)

Ikan patin (Pangasius hypopthalamus) merupakan salah satu komoditas unggulan di Provinsi Riau dengan kandungan minyak yang tingga sehingga berpotensi untuk diekstrak menjadi sumber asam lemak yang bisa bermanfaat bagi kesehatan. Penambahan antio

23-06-2024
Review: Studi Kandungan Fitokimia dan Aktivitas Antimikroba Daun Buas Buas (Premna cordifolia)

Gusti Ngurah Trisna (2024)

Tumbuhan buas buas (Premna cordifolia L.) yang termasuk ke dalam famili Lamiaceae dilaporkan aktif sebagai agen antimikroba. Narrative review ini bertujuan untuk mengkaji penelitian terbaru mengenai kandungan senyawa fitokimia dan aktivitas antim

23-06-2024
Formulasi Sediaan Blush on Cream dengan Pewarna Ekstrak Kelopak Bunga Rosella (Hibiscus sabdarifa)

Dwi Agustina (2024)

Blush on atau perona pipi merupakan kosmetik dekoratif pemberi warna merah pada pipi sehingga wajah tampak terlihat lebih cantik, segar dan berdimensi. Saat ini banyak sediaan perona pipi (blush) yang menggunakan pewarna yang berbahaya. Oleh sebab

23-06-2024
Evaluasi Zona Hambat Berbagai Sediaan Topikal Anti Jerawat Dari Ekstrak Daun Beluntas (Pluchea indica L.)

Ni Ketut Sri Anggreni (2024)

Jerawat merupakan gangguan peradangan kronis pada kulit yang dapat mempengaruhi unit folikel kelenjar sebaceous. Munculnya jerawat disebabkan oleh adanya pertumbuhan bakteri yang menginfeksi kulit sehingga terjadi peradangan pada kulit. Umumnya

23-06-2024
Analisa Tingkat Pengetahuan dan Perilaku Masyarakat Terhadap Penggunaan Antibiotik di Kelurahan Dawi-Dawi, Kecamatan Pomalaa, Kabupaten Kolaka, Provinsi Sulawesi Tenggara

Devitha Farah Mahdiyah (2024)

Antibiotik merupakan terapi efektif yang baik dalam penyembuhan penyakit yang di sebabkan oleh bakteri sehingga pasien ataupun masyarakat kadang menggunakannya sebagai obat swamedikasi. Karena kurangnya pengetahuan maupun perilaku masyarakat ini

23-06-2024
Pemanfaatan Getah Daun Jarak Pagar (Jatropha curcas L.) sebagai Bahan Aktif Formulasi Pasta Gigi

Ida Ayu Gendari (2024)

Pengetahuan seseorang mengenai permasalahan gigi dan mulut sangat penting dalam mendukung perilaku untuk menjaga kesehatan gigi dan mulut. Hal tersebut tidak dapat disepelekan, sehingga perlu dilakukan upaya pencegahan dengan rutin menyikat gigi

23-06-2024
Review Aktivitas Analgesik Kenanga (Cananga odorata) dan Temulawak (Curcuma xanthorrhiza) dalam Usada Tenung Tanyalara

I Gusti Agung Krisna Larashati (2024)

Pemanfaatan obat tradisional termasuk ke dalam kekayaan budaya Indonesia yang didasarkan pada pengetahuan dan kepercayaan berbagai etnis. Usada Tenung Tanyara merupakan naskah tulisan yang memuat sistem pengobatan enam golongan penyakit yakni dem

23-06-2024
Skrining Fitokimia dan Profil KLT Ekstrak dan Fraksi dari Daun Berenuk (Cresentia cujete L.) serta Uji DPPH

Brigita Olivia Intan Kinam (2024)

Daun Berenuk atau Maja (Cresentia cujete L.) merupakan tanaman yang tumbuh pada daerah tropis. Di Indonesia, pemanfaatan Daun Berenuk bagi kesehatan belum dimanfaatkan secara maksimal, serta masih minimnya penelitian mengenai tanaman ini. Untuk d

23-06-2024
Literature Review: Formulasi Obat Kumur Pencegah Infeksi Rongga Mulut Berbasis Nanopartikel Perak Ekstrak Daun Keji Beling

Ni Wayan Sukma Pramitha Sari (2024)

Kesehatan rongga mulut berpengaruh terhadap kualitas hidup serta status gizi masyarakat sebab rongga mulut merupakan organ terluar pada sistem pencernaan yang berinteraksi langsung dengan lingkungan. Berdasarkan Riset Kesehatan Dasar RI Tahun 201

23-06-2024
Formulasi Sediaan Masker Gel Peel Off dari Minyak Atsiri Sereh (Cymbopogon citratus)

Annisa (2024)

Sereh (Cymbopogon citratus) merupakan salah satu tanaman penghasil minyak atsiri yang dikenal dengan nama Lemongrass oil dengan kandungan utama senyawa sitral. Minyak atsiri sereh diketahui memiliki aktivitas antioksidan. Aktivitas antioksidan mi

23-06-2024
Potensi Rimpang Temu Kunci (Boesenbergia pandurata Roxb.) sebagai Bahan Aktif Produk Kecantikan Alami yang Ramah Lingkungan

Ni Putu Indah Widyantari (2024)

Antusiasme masyarakat menggunakan produk kecantikan semakin meningkat dengan penggunaan produk lokal yangiiberbahan dasar alamiiiatauiibackiitoiinature. Haliiini dikarenakan, penggunaan produk kecantikan alami yang ramah lingkungan mampu menghasi

23-06-2024
Kajian Interaksi Obat Pasien Gagal Ginjal Kronis Di Instalasi Rawat Inap Rumah Sakit Samarinda Medika Citra

Angelina Theodora Hanyaq (2024)

Pasien gagal ginjal kronis umumnya memiliki penyakit penyerta yang mengakibatkan pengobatan Gagal Ginjal Kronis menjadi kompleks sehingga jumlah obat yang diterima pasien meningkat. Banyaknya obat yang dikonsumsi pasien akan meningkatkan potensi

23-06-2024
Potensi dan Mekanisme Kerja Berbagai Tanaman Herbal dalam Membantu Mengatasi Obesitas

Dewa Julio Angga Purnama (2024)

Obesitas adalah salah satu ancaman kesehatan yang sangat serius dan dihadapi semua negara. Masalah kesehatan ini sering berasosiasi dengan penyakit lain seperti diabetes dan gangguan kardiovaskuler. Penyebab obesitas pada seseorang bervariasi mul

23-06-2024
Kajian Literatur: Perbandingan Efektivitas Antiplatelet Kombinasi AspirinClopidogrel dan Aspirin pada Stroke Isk

Salwa Octariani (2024)

Stroke iskemik adalah kondisi akibat dari kurangnya aliran darah ke otak. Salah satu terapi yang digunakan untuk penyakit stroke iskemik ialah antiplatelet. Terapi antiplatelet tunggal umumnya lebih disukai daripada terapi antiplatelet kombinasi,

23-06-2024
Pemanfaatan Ekstrak Ikan Gabus (Channa striata) untuk Penyembuh Luka pada Pasien Diabetes Mellitus (Ulkus Diabetikum)

Sita Udayanti (2024)

Diabetes melitus merupakan penyakit metabolisme karbohidrat yang membuat penederita mengalami kenaikan kadar glukosa darah yang disebabkan sekresi insulin. Penderita diabetes melitus rentang dengan adanya komplikasi ulkus diabetikum (luka diabete

23-06-2024
Studi Literatur Aktivitas Antiinflamasi sebagai Penyembuh Luka Tumbuhan Obat Terpilih Berdasarkan Ramuan Usada Tiwas Panggung

Laksmi Dewi (2024)

Usada Tiwas Panggung merupakan usada yang akhir pengobatannya diberikan mantra sepuluh aksara suci. Dalam Usada Tiwas Panggung, pengobatan luka borok dapat diobati dengan menggunakan tanaman Mesua ferrea, Areca catechu, Terminalia bellirica, dan

23-06-2024
Kajian Literatur Tanaman Sirih Merah, Binahong, dan Pegagan Sebagai Penyembuh Luka Insisi

Salinding Irene Septiani (2024)

Luka merupakan kerusakan suatu fungsi jaringan dan struktur tubuh. Luka insisi dapat terjadi secara disengaja maupun tidak disengaja oleh instrumen tajam maupun tumpul. Tanaman sirih merah, binahong, dan pegagan merupakan tanaman yang dapat menye

23-06-2024
Pemanfaatan Ikan Gabus (Channa striata) dalam Pengobatan Osteoarthritis

A.A Ayu Dessy Satriani Putri (2024)

Penyakit degeneratif merupakan penyakit yang sering terjadi pada proses penuaan. Di seluruh dunia, jumlah penyakit degeneratif terus bertambah. Salah satu penyakit degeneratif yang sering dialami yaitu osteoarthritis. Di Indonesia, prevalensi os

23-06-2024
Literature Review: Bahan Alam yang Berpotensi Sebagai Antidiabetes

Novalinda (2024)

Antidiabetes merupakan pengobatan yang saat ini banyak dibutuhkan bagi penderita diabetes, karena biaya pengobatannya semakin tinggi, sehingga direkomendasikan menggunakan herbal sebagai pengobatan alternatif. Penelitian ini bertujuan untuk menge

23-06-2024
Aktivitas Antibakteri Kombinasi Ekstrak Mangifera laurina, Ruellia tuberosa L. dan Leucobryum sp. pada Luka Penderita Diabetes

Rodesia Mustika Roza (2024)

Mangifera laurina termasuk salah satu mangga liar di Sumatra yang memiliki kandungan antioksidan, fenol dan flavonoid yang tinggi. Tanaman Ruellia tuberosa L dan Leucobryum sp. diketahui memiliki sifat antibakteri. Perpaduan tiga tumbuhan ini dih

23-06-2024
Kajian Literatur: Aktivitas Antioksidan Ekstrak Tanaman Cempedak (Artocarpus champeden Spreng)

Aulia Alfath Rahmawati (2024)

Antioksidan merupakan senyawa yang dapat menangkal radikal bebas. Salah satu tanaman yang memiliki aktivitas antioksidan adalah cempedak yang mengandung senyawa flavonoid. Penulisan ini bertujuan mengetahui aktivitas antioksidan tanaman cempedak

23-06-2024
Pengaruh Konsentrasi NaOH dan Waktu Pengadukan terhadap Karakteristik Sabun Pada Opaque Lidah Buaya (Aloe vera L.)

Pande Putu Ayu Laksmi Dewi (2024)

Sabun kecantikan komersial sekarang ini menggunakan senyawa sintetis yang tidak baik jika digunakan dalam jangka waktu panjang. Salah satu bahan alami yang dapat ditambahkan dalam sabun kecantikan adalah lidah buaya (Aloe vera Linn). Lidah buaya

23-06-2024
SCOPING REVIEW: POTENSI EKSTRAK KECAMBAH BERAS HITAM (ORYZA SATIVA L) UNTUK TERAPI DIABETES MELITUS DAN DISLIPIDEMIA

Sudana Fatahillah Pasaribu (2024)

Latar belakang: Diabetes melitus adalah penyakit yang disebabkan gangguan metabolisme glukosa dan atau gangguan fungsi insulin. Diabetes melitus meningkatkan risiko terjadinya dislipidemia, terkait adanya peningkatan stres oksidatif dan gangguan

23-06-2024
Formulasi dan Evaluasi Nutrasetikal Gummy Candy dari Perasan Daun Kelakai (Stenochlaena Palustris (Burm.F.) Bedd)

Winiaksa Tri Asdini (2024)

Daun kelakai (Stenochlaena palustris (Burm.F.) Bedd) merupakan tumbuhan khas Kalimantan Timur dengan kandungan zat besi yang tinggi yang berpotensi mengatasi anemia. Perasan daun kelakai diformulasi menjadi sediaan nutrasetikal gummy candy dengan

23-06-2024
Design and optimization of diclofenac gel 1% as an analgesic and anti-inflammatory for topical use

Nilia de la Paz Martín-Viaña (2024)

Context: Diclofenac sodium is a compound that belongs to the NSAIDs, it has pronounced anti-rheumatic, anti-inflammatory, analgesic and antipyretic properties. Objective: To carry out the design and optimization of the formulation of a diclo

23-06-2024
Hubungan antara Pengetahuan dan Perilaku Masyarakat Kecamatan Biatan Kabupaten Berau terhadap Penggunaan dan Resistensi Obat Antibiotik

Vina Mardiyanti Aprilia (2024)

Antibiotik merupakan obat yang digunakan untuk mengatasi infeksi. Infeksi merupakan suatu masalah penyakit yang sering terjadi di negara berkembang Indonesia. Tujuan dari penelitian ini adalah untuk mengetahui tingkat pengetahuan dan perilaku mas

23-06-2024
Formulasi Lilin Aromaterapi Berbahan Aktif Minyak Atsiri Sereh Wangi (Cymbopogon winterianus) dan Jeruk Lemon (Citrus limon)

Vika Aura Rislianti (2024)

Aromaterapi adalah terapi yang menggunakan senyawa aroma untuk mengobati, mengurangi, atau mencegah suatu penyakit, infeksi, dan kegelisahan dengan cara menghirupnya. Sereh wangi (Cymbopogon winterianus) dan Jeruk lemon (Citrus limon) memiliki mi

23-06-2024
MICPS1-001-HS: ASSESSING MENTAL HEALTH ISSUES OF THE ROHINGYA FEMALE REFUGEES ATTENDING IMARET MOBILE CLINIC

Ahmad Rashidi Mohamed Tahir (2024)

Context: The Rohingyan people in Myanmar are a severely persecuted minority ethnic group constituting one of the largest stateless ethnic groups; thousands of them reside in refugee camps in south-eastern Bangladesh. There have been few studies o

23-06-2024
Uji Aktivitas Antikoagulan Ekstrak Daun Ciplukan (Physalis Angulata L) Secara Invitro

Uswatun Khasanah Duri Putri (2024)

Daun ciplukan (Physalis angulata L) secara empiris digunakan sebagai obat hiperkoagulasi. Kandungan metabolit sekunder flavonoid berpotensi sebagai antikoagulan. Penelitian ini bertujuan untuk mengetahui hasil rendemen ekstrak dan fraksi daun cip

23-06-2024
Penggunaan Soy wax dan Beeswax sebagai Basis Lilin Aromaterapi

Theresia Fenny Oktarina (2024)

Penggunaan lilin parafin secara terus menerus menghasilkan polutan yang berdampak buruk bagi kesehatan dan lingkungan. Lilin soy wax dan beeswax merupakan bahan yang ramah lingkungan karena menghasilkan polutan yang lebih sedikit. Penelitian ini

23-06-2024
Vitamin D and Cardiovascular Disease Risk: Using Outcomes to Guide Future Nutrition Science †

Diego Moretti (2024)

Despite positive associations between micronutrient intake, status, and health outcomes, many randomized controlled trials (RCT) of vitamins are null. Standards to establish causality in biological systems include the Bradford Hill criteria, the

23-06-2024
Evaluating Affordability of Healthier Diets in Four African Countries †

Joaquin Ameller Pavez (2024)

Between 702 and 828 million people around the world were affected by hunger in 2021. The prevalence of undernourishment relentlessly continues to affect the world, and particularly Sub Saharan Africa (23.2% in 2021). Exacerbated inequalities acro

23-06-2024
Karakteristik Granul Gastroretentive Mukoadhesif Amoksisilin dengan menggunakan Kitosan-Alginat, Na.CMC dan HPMC

Siti Rofi’ah Febryani (2024)

Gastroretentive Drug Delivery System (GRDDS) merupakan sediaan lepas lambat yang dapat terikat pada permukaan sel epithel atau mukosa lambung, sedangkan mukoadhesif merupakan salah satu mekanisme kerja dari Gastroretentive Drug Delivery S

23-06-2024
NewStandards for Nutrition Science, Concepts and Methods—LowSocioeconomic Status and Overweight: Participatory Research Designs for the Development of Interventions †

Tim van Zutphen (2024)

Background: The heavy burden of obesity on individuals and society has attracted a lot of attention, and many strategies to prevent or reverse it have been developed. Consequently, many reviews exist on this topic, However, similar to the bulk o

23-06-2024
Kajian Potensi Interaksi Obat pada Pasien COVID-19 di Rumah Sakit X Kota Samarinda

Shofia Siza Maulidia (2024)

Coronavirus disease 2019 (COVID-19) adalah penyakit infeksi saluran pernapasan yang disebabkan oleh virus corona yang dikenal dengan sebutan SARS-CoV-2 dan kini sedang menjadi pandemi di seluruh dunia. Tatalaksana pengobatan pada pasien COVID-19

23-06-2024
Introduction of the European Regulatory Framework for New Sweeteners and Sweeteness Enhancers and Its Role as a Facilitator or Barrier to Innovation: Results from the SWEETProject †

Lada Timotijevic (2024)

There is a growing consumer interest and public health mandate to reduce sugar intake, and an increased iimpetus to innovate in the food sector to develop new and more acceptable sweeteners and sweetness enhancers (S&SEs) as low- or non-calorific

23-06-2024
Optimasi Konsentrasi VCO Terhadap Stabilitas Fisik Facewash dan Uji Antibakteri Ekstrak Daun Kelapa Sawit (Eleais Guineensis Jacq.) pada Bakteri Penyebab Jerawat

Selin Cenora Aritonang (2024)

Daun kelapa Sawit (Elaeis guineensis Jacq.) merupakan limbah dari perkebunan kelapa sawit yang memiliki senyawa alkaloid dan steroid yang berfungsi sebagai antibakteri penyebab jerawat. Penelitian ini bertujuan untuk mengetahui konsetrasi ekstrak

23-06-2024
Development of a Diet Quality Score and Adherence to the Swiss Dietary Recommendations for Vegans †

Leonie H. Bogl (2024)

Background: Vegan diets have recently gained popularity in Switzerland and abroad. A method to evaluate the diet quality of the vegan population for research and clinical practice is currently not available. Therefore, the aim of the present stud

23-06-2024
Efektivitas Nutrisi Medik Berbahan Aktif Mengkudu dan Apel Manalagi Terhadap Penurunan Kadar Glukosa Darah

Selfia (2024)

Noni (Morinda citrifolia L.) contains saponin compounds that work to stimulate insulin secretion from ?-pancreatic cells and manalagi apples (Malus sylvestris Mill.) contain pectin which functions to delay the emptying of food in the stomach, bin

23-06-2024
NewStandards for Nutrition Science, Concepts and Methods—Novel Approach to Substantiate Cause- and-Effect Relationships in Nutritional Science by Ranking Studies and Subsequent Statistical Modelling †

Wim Calame (2024)

In any scientific field, demonstrating cause-and-effect relationships is of the utmost importance, however difficult to achieve. The present study aims to establish an objective approach to substantiate cause-and-effect relationships. Our approa

23-06-2024
Kajian Konsentrasi Ekstrak Etanol Daun Karamunting (Melastoma malabathricum L) dalam Sediaan Krim terhadap Sifat Fisik dan Aktivitas Antioksidan

Rohani (2024)

Daun Karamunting (Melastoma malabathricum L) telah banyak digunakan dalam pengobatan tradisional karena memiliki berbagai aktivitas farmakologis yang berkaitan dengan senyawa metabolit sekunder yang dikandungnya diantaranya flavonoid dan tanin. T

23-06-2024
Isolasi dan Karakterisasi Kitosan dari Limbah Cangkang Kerang Asia (Corbicula fluminea)

Rizki Noor Amelia (2024)

Kitosan adalah zat yang terkandung dalam cangkang kerang yang merupakan biopolymer terbanyak setelah selulosa. Penelitian ini bertujuan untuk mengetahui rendemen terbaik kitosan hasil isolasi limbah cangkang kerang Asia (Corbicula fluminea) berda

23-06-2024
Multi-Faceted Nutritional Science Demonstrated through the Prism of Sugar—A Scoping Review on Sugar Intake Associated with Quality of Life in Children and Adolescents †

Stefania Noerman (2024)

Given our current knowledge and insights into the nature of nutrition, a simplistic ap proach to understanding the role of nutrition in relation to health outcomes appears insufficient as a scientific base for setting nutrition policies. To raise

23-06-2024
Karakteristik Pasien Terkonfirmasi Coronavirus disease (COVID-19) di RS X Samarinda Periode Maret-Desember 2020

Ridha Siti Ruhama (2024)

Coronavirus disease (COVID-19) merupakan virus yang telah menjadi pandemi dunia termasuk Indonesia. Kalimantan Timur merupakan provinsi dengan jumlah kasus per 28 Mei 2021 mencapai 71.092 kasus terkonfirmasi positif COVID-19. RS X Samarinda memil

23-06-2024
Weight Loss Effect of an App-Based Multimodal Lifestyle Intervention in Adults with Obesity—A Randomized Controlled Trial †

Kathrin Gemesi (2024)

Quality-proven Digital Health Applications (DiGAs) or “apps on prescription” in Germany extend obesity treatment options. This 24-week single-center randomized controlled trial aimed to examine the weight-lowering effect of an evidence-based

23-06-2024
Kajian Efektivitas Pengobatan pada Pasien Stroke Iskemik di Instalasi Rawat Inap RSUD Nunukan

Rida Wahda Maulida Tahir (2024)

Stroke iskemik terjadi akibat adanya obstruksi pada pembuluh darah yang mensuplai ke otak. Obstruksi terjadi karena peningkatan lemak yang melapisi pembuluh darah atau aterosklerosis. Aterosklerosis akan menyebabkan thrombosis serebral dan emboli

23-06-2024
Is Thinness Associated with Poorer Diet and Nutrient Intake and Status in Danish 8–11-Year-Olds? †

Anne V. Aurup (2024)

Thinness is used to denote low BMI in children and may be a marker of undernutrition. However, despite prevalence rates of up to 10%, thinness in children is highly overlooked in high income countries, and we have little knowledge about the diet

23-06-2024
Formulasi Sediaan Liniment Aromaterapi dari Minyak Atsiri Bunga Kenanga (Cananga odorata)

Ragil Sekar Ayuni (2024)

Minyak atsiri kenanga memiliki potensi sebagai antidepresan dan relaksan sistem saraf dengan kandungan senyawa yaitu linalool dari golongan monoterpen. Maka, inovasi sediaan farmasi topikal dengan bahan aktif minyak atsiri kenanga menjadi hal yan

23-06-2024
Adherence to French Dietary Guidelines Is Associated with a Reduced Risk of All-Cause, Cardiovascular Diseases and All, Breast and Lung Cancer Mortality in the E3N COHORT†

Chloé Marques (2024)

Background and objectives: Diet is a modifiable risk factor of non-communicable diseases. The French dietary guidelines, updated in 2017, provide recommendations for a healthier diet. We aimed to study the association between adherence to these d

23-06-2024
Uji Antelmintik dari Ekstrak Etanol Daun Kadamba (Mitragyna speciosa)

Putri Natasya Magdalena (2024)

Penyakit yang disebabkan parasit terutama cacing pada hewan di peternakan merupakan salah satu permasalahan yang sering dihadapi peternak. Penyakit cacingan dapat menurunkan produktivitas ternak dan menjadi penyebab turunnya nilai jual ternak di

23-06-2024
Potensi Seduhan Daun Pepaya (Carica papaya L.) Kombinasi Madu Terhadap Intensitas Nyeri Haid (Dysmenorrhea) pada Wanita

Pakendek Fefryani (2024)

Haid merupakan pertanda seorang remaja sudah memasuki pubertas. Haid dapat menyebabkan nyeri atau kram yang disebut dismenore. Dalam penelitian ini digunakan 1 lembar daun pepaya (Carica papaya L.) yang dikombinasikan 30ml madu. Tujuan dalam penel

23-06-2024
Kajian Penggunaan Obat Off-Label Pada Penyakit ISPA Pasien Pediatri di RSUD Majene

Nurul Syafitri AR (2024)

Infeksi Saluran Pernapasan Akut (ISPA) merupakan infeksi yang menyerang saluran pernapasan manusia dengan jumlah penderita paling banyak ditemukan pada usia balita. Keterbatasan jenis obat yang bisa digunakan pada rentang usia anak usia 0-2 tahun

23-06-2024
ACross-Sectional Study on Micronutrient Adequacy and Associated Factors among School-Going Adolescent Girls †

Priyanka Pareek (2024)

Background: Micronutrient deficiency is also referred as hidden hunger, and it increases the global disease burden. Adolescent girls need nutritional care, and their poor dietary intake leads to micronutrient deficiency and poor maternal outcomes

30-11--0001
Uji Antioksidan Ekstrak Metanol Kulit Batang Pule (Alstonia scholaris) Khas Kalimantan dengan Metode DPPH

Nur Halimah (2004)

Pule (Alstonia scholaris) merupakan salah satu tanaman yang secara empiris sering digunakan dalam pengobatan. Kulit batang pule memiliki kandungan flavonoid yang umumnya dapat digunakan sebagai antioksidan. Penelitian ini bertujuan untuk mengetah

23-06-2024
Defining Public Health Nutrition Goals Based on Food Balance Sheets—A Proof-of-Principle †

Kurt Gedrich (2024)

Background and objectives: Food balance sheets (FBSs) provide comprehensive annual information on a country’s food supply, reflecting possible trends in a population’s overall food consumption. However, FBSs essentially refer to agricultural

23-06-2024
Skrinning Aktivitas Antimikroba Ekstrak Etanol Daun Mekai (Albertisia sp.)

Nur Aini Buring Incau (2024)

Albertisia sp. merupakan tumbuhan yang digunakan sebagai obat mata karena infeksi saluran mata atau kelopak mata oleh masyarakat Dayak diKabupaten Malinau, Kalimantan Utara. Penelitian ini bertujuan untuk mengetahui apakah ekstrak daun mekai memi

23-06-2024
Philosophical Reflection on Holism and Reductionism in Nutrition Science †

Eline Baltussen (2024)

Nutrition, as a science, is facing challenges. While issues regarding obesity, chronic diseases, andsustainability are becoming more pressing, nutrition science is encountering limitations regarding novel insights, trust, and social relevance. In

23-06-2024
Pengaruh Pemberian Kombinasi Jus Belimbing Manis (Averrhoa carambola) dan Labu Siam (Sechium edule) terhadap Pemeliharaan Tekanan Darah

Nugrahiwulan Oktaviani (2024)

Buah belimbing manis (Averrhoa carambola) dan labu siam (Sechium edule) mengandung kalium yang dapat menjaga keseimbangan tekanan darah. Penelitian ini bertujuan untuk mengetahui gambaran karakteristik responden meliputi jenis kelamin, umur, pend

23-06-2024
Exploring the Impact of Basal Metabolic Rate Equations on Goldberg Cut-Offs: Influence on Estimated Usual Energy Intake in the Elderly †

Živa Lavriša (2024)

The accurate assessment of usual dietary intake (DI) in the elderly can be difficult, and its reliability can be affected by several factors, including misreporting, which is one of the major sources of error regardless of the method used. The G

23-06-2024
Pengaruh Trietanolamin pada Basis Krim Minyak dalam Air yang Berbahan Dasar Asam Stearat dan Setil Alkohol

Novita Sari (2024)

Krim merupakan sediaan setengah padat dengan satu atau lebih bahan obat yang terdispersikan dalam dua tipe emulsi yaitu krim tipe air dalam minyak (A/M) dantipe minyak dalam air (M/A). Krim tipe minyak dalam air memiliki kadar air yang tinggi seh

23-06-2024
Assessment of the Effects of Updated Nutri-Score Nutrient Profiling Algorithm Using a Representative Slovenian Food Supply Dataset †

Edvina Hafner (2024)

Background: Front-of-package nutrition labelling (FOPNL) is an important public health tool for promoting healthier food choices. Therefore, the European Commission has committed to proposing harmonised mandatory FOPNL in Europe. A relevant optio

23-06-2024
Evaluasi Penggunaan Obat pada Pasien Dispepsia di Rumah Sakit Samarinda Medika Citra Tahun 2021

Novia Syafitri (2024)

Dispepsia didefinisikan sebagai rasa nyeri atau rasa tidak nyaman yang terletak pada perut bagian atas, yang disertai dengan keluhan-keluhan lain. Untuk mencapai tujuan dari terapi obat yang diinginkan tentunya perlu pemberian obat secara tepat k

23-06-2024
Changes in Eating Habits and Contributing Factors during the COVID-19 Pandemic among Medical Students in the Slovak Republic †

Jana Babjakova (2024)

Due to the outbreak of the new coronavirus disease, many lifestyle alterations occurred. Changes in eating habits and contributing factors during the COVID-19 pandemic were examined. A cross-sectional anonymous online survey was conducted among s

23-06-2024
Capacity Development and Harmonization of Food Consumption Data Collection in EFSA EU Menu National Dietary Surveys in Balkan Region-Building: The Evidence Base for Diet Monitoring and Food Systems Transformation †

Mirjana Gurinovic (2024)

Harmonized and standardized collection, processing, and analysis of individual dietary data is essential for nutrition assessment and informed policy decision making. To underpin the harmonizationoffoodconsumptiondatacollectionmethodologiesandthe

23-06-2024
Optimisasi Carbopol Sebagai Basis Gel pada Gel Antiseptik Berbasis Alkohol

Noor Linda Febrianie (2024)

Gel antiseptik berbasis alkohol dianggap mampu menggantikan cuci tangan menggunakan sabun dan mampu menghambat tumbuhnya virus. Beberapa jenis basis gel mempunyai kelemahan sukar bercampur dengan alkohol sebagai bahan utama dalam antiseptik berba

23-06-2024
Efektivitas Jenis Bahan Masker Kain Berdasarkan Kemampuan Penyaringan Mikroba

Nilam Sari (2024)

Masker kain merupakan masker yang dapat digunakan berulang dan terbuat dari material kain yang lebih tebal. Masker kain yang beredar ditengah masyarakat belum terjaminan kualitasnya. Penelitian ini bertujuan untuk mengetahui efektivitas bahan mas

23-06-2024
Effects of Plant-Origin Superoxide Dismutase Supplementation on Selected Parameters of Inflammation and White Blood Cell Count in Athletes †

Olina Dudašova Petrovicova (2024)

Background and objectives: Regular moderate exercise is considered a protector against chronic inflammatory diseases. Intense exercise causes a significant release of pro-inflammatory cytokines and free radicals depending on exercise intensity an

23-06-2024
Isolasi Fungi Endofit Daun Kopi Robusta (Coffea canephora)

Nilam Ratna Rizkyanti (2024)

Fungi Endofit adalah organisme yang hidup pada jaringan tumbuhan yang berpotensi menghasilkan metabolit sekunder yang sama dengan inanganya. Penelitian ini bertujuan untuk melakukan karakterisasi dan isolasi fungi endofit dari daun kopi Robusta (

23-06-2024
Adherence to the Mediterranean Diet and the Consumption of Its Food Groups in a Sample of over 10,000 Italian Adults †

Sofia Lotti (2024)

Adherence to the Mediterranean diet (MD) has been shown to promote health and reduce the prevalence of several chronic diseases. However, to date, more and more countries in the Mediterranean basin seem to be moving away from their traditional ea

23-06-2024
Nutritional and Anthropometric Status of Serbian Adults 10–74 Years Old: Results from European Food Safety Authority (EFSA) EU MenuFoodConsumptionSurvey 2017–2021 †

Jelena Mileševic (2024)

TheSerbianNationalFoodConsumptionSurveyonadultsfrom10to74yearsold,including pregnant women and vegetarians, was conducted in compliance with the EFSA EU Menu project support and guidance from 2017 to 2022. Valid data were collected from a total o

23-06-2024
Aktivitas Penghambatan Radikal Bebas Difenil Pikril Hidrazil (DPPH) Ekstrak Daun Macaranga magna Turrill

Minarti (2024)

Penyakit degeneratif merupakan salah satu penyakit yang mempunyai jumlah penderita cukup banyak di Indonesia dan seluruh dunia, salah satu penyebab banyaknya penderita penyakit degeneratif seperti diabetes dan kanker adalah banyaknya paparan radi

23-06-2024
Preface and Statement of Peer Review

Philip C. Calder (2024)

This publication collates the proceedings of the 14th European Nutrition Conference, held from 14 to 17 November 2023 in Belgrade, Serbia. The conference was organized by the Federation of European Nutrition Societies (FENS) and local organizer

23-06-2024
Aktivitas Antioksidan pada Formulasi Minuman Serbuk Instan dari Sari Daun Suruhan (Peperomia pellucida)

Meilina Purnama Ningrum (2024)

Daun suruhan secara empiris telah digunakan sebagai obat, karena memiliki aktivitas antioksidan yang dapat menangkal radikal bebas penyebab berbagai penyakit. Penelitian ini bertujuan untuk mengetahui aktivitas antioksidan minuman serbuk instan.

23-06-2024
Aktivitas Antioksidan Ekstrak Etanol Daun Kelapa Sawit (Elaeis guineensis Jacq.)

Masrurotin Zumaro (2024)

Indonesia merupakan negara dengan kekayaan alam yang melimpah dan hampir segala jenis tumbuhan dapat tumbuh di wilayah negara ini. Salah satunya ialah daun kelapa sawit (Elaeis guineenis Jacq.) mengandung senyawa-senyawa terpenoid, steroid, alkal

23-06-2024
Report from the Scientific Poster Session at the 16th Annual Cardiometabolic Health Congress in National Harbor, USA, 14–17 October 2021

Shpetim Karandrea (2024)

The ever-increasing presence of cardiometabolic risk continues to be a major challenge for health care providers in the United States (US). Current estimates suggest approximately 23–38% of all adults in the US have metabolic syndrome, a const

23-06-2024
Tingkat Pengetahuan dan Perilaku Swamedikasi pada Mahasiswa Universitas Mulawarman

Maria Rotua Simanjuntak (2024)

Swamedikasi adalah proses pengobatan yang dilakukan sendiri oleh seseorang tanpa mengunakan resep dari dokter. Swamedikasi sebagai salah satu upaya yang banyak dilakukan masyarakat dalam mengatasi penyakit ringan. Salah satu faktor yang dapat mem

23-06-2024
Proceedings of the First Irish Alcohol Hangover Research Seminar †

Lydia E. Devenney (2024)

On 19 November 2021, the first Irish Alcohol Hangover Research Seminar was held at the Atlantic Technological University, Donegal. In these proceedings, the presentations of the seminar are summarized. Topics discussed included the pathology and

23-06-2024
Studi Evaluasi Efek Samping Penggunaan Vaksin COVID-19 Terhadap Masyarakat Sebatik Timur

Lutfiatun Nisak (2024)

Vaksinasi merupakan upaya pencegahan yang efektif penularan penyakit dan menjadi kewajiban pemerintah menjamin ketersediaan vaksin khususnya di masa pandemic COVID-19 ini di mana ketersediaan vaksin mayoritas baru memiliki ijin Emergency Use Appr

23-06-2024
Remarks and Abstracts of the First Sustainable Globe Conference 2021 †

Shakil Regmi (2024)

The First Sustainable Globe Conference 2021 was held virtually from 8 to 10 September 2021. The partner organizers were Martin-Luther-University Halle-Wittenberg from Germany, RootsGoods Private Limited from India, and the Vriksha Foundation from

23-06-2024
Kombinasi Ekstrak Etanol 96?un Teh (Camellia sinensis (L.) Kuntze) dan Daun Yakon (Smallanthus sonchifolius) sebagai Penghambat Enzim ?-glukosidase

Lilik Sulastri (2024)

Diabetes melitus merupakan salah satu penyakit degeneratif berupa gangguan metabolik yang ditandai dengan meningkatnya kadar glukosa darah dan gangguan metabolisme insulin. Daun yakon dan daun teh mengandung senyawa fenol yang memiliki aktivitas

23-06-2024
ATrend Analysis of Research on the Flipped Classroom in L2 Learning before and after COVID-19 †

Merve Köksal (2024)

The aim of this research is to examine the EFL flipped classroom trend before and during COVID-19 by the frequent types of research designs and topics investigated in the studies. For this purpose, a content analysis was used as the research met

23-06-2024
Abstracts of the 45th Annual Scientific Meeting of the Nutrition Society of Australia †

Sandra Iuliano (2024)

The 45th Annual Scientific Meeting of the Nutrition Society of Australia was held virtually from 2–3 December 2021. The theme of the meeting was Nutrition: Opportunities for Nutrition Science in a New Era. Abstracts were submitted from 13 count

23-06-2024
Pola Penggunaan Antimalaria pada Pasien Malaria di Instalasi Rawat Inap RSUD Jayapura Periode Januari–Desember 2020

Kornelius Yustico Trimedya Purba (2024)

Kota Jayapura merupakan salah satu daerah endemik malaria di Provinsi Papua. Penggunaan obat antimalaria di rumah sakit telah menyesuaikan dengan pola keberhasilan terapi pada tahun-tahun sebelumnya. Penelitian ini bertujuan untuk mengetahui pola

23-06-2024
Plant Translocation for Threatened Species Conservation †

Anurag Dhyani (2024)

A training school on Plant Translocation—Theory and Techniques was held on 24–26 March 2021 organized virtually at the Botanic Garden of Rome, Italy. The aim of the course was to train budding scientists in the field of threatened plant rest

23-06-2024
Pengaruh Pemberian Aromaterapi Pandan Wangi (Pandanus amaryllifolius) dan Lemon (Citrus limon L) dalam Menurunkan Tekanan Darah

Jihan Al-Mira (2024)

Pandan wangi dan lemon memiliki kandungan berupa senyawa linalool sebanyak 6% didalam pandan wangi dan sebanyak 20-50% terdapat didalam lemon senyawa linalool sangat bermanfaat untuk menstabilkan saraf sehingga dapat menimbulkan efek tenang. Pene

23-06-2024
Experimental Study on Hollow Blocks with Wastes †

Ligia Hanuseac (2024)

The article presents an experimental study on concrete blocks prepared by using waste types such as fly ash as a cement substitution, waste of plastic bottles and wood waste as replacements for sand and polyester fibers waste as a dispersed reinf

23-06-2024
Pengaruh Pelarut, Suhu dan pH Terhadap Pigmen Antosianin dari Ekstrak Kulit Buah Naga Merah (Hylocereus Polyrhizus)

Gusti Alamsyah Abdil Almajid (2024)

Kulit buah naga merah (Hylocereus polyrhizus) merupakan limbah hasil pertanian yang mengandung pigmen alami antosianin yang cukup tinggi. Tujuan dari penelitian ini yaitu untuk mengetahui bagaimana pengaruh pelarut, suhu dan pH terhadap kadar tot

23-06-2024
Behavior of Natural Organic Polymer-Based Plaster Mortars under the Influence of Water

Alexandra Olga Pintea (2024)

The influence of polymers upon building materials has been present since ancient times, but it was neglected for a long period. The present research discusses the e ect of natural organic polymers(casein, rice, egg)intheformulaofclassicalplasteri

23-06-2024
Optimasi Basis Formulasi Sediaan Handsanitizer Gel Ekstrak Daun Sirih Hitam (Piper betle var nigra) Sebagai Antibakteri

Felina Alfiany (2024)

Tumbuhan Daun Sirih Hitam (Piper betle var nigra) merupakan salah satu tanaman yang berpotensi sebagai antibakteri. Penelitian ini merupakan eksperimental laboratorium dan bertujuan untuk mengetahui konsentrasi basis handsanitizer gel yang optimu

23-06-2024
Robotic Arms with Anthropomorphic Grippers for Robotic Technological Processes

Ionel Staretu (2024)

Theroboticarmsofthehumanarmtype,so-calledcollaborativerobots, havebeenimproved, optimized, and diversified greatly in recent years. However, most of them are still equipped with mechanical grippers with plier-like jaws. Equipping these robotic ar

23-06-2024
Innovative Materials with Complex Applicability

Marta Ioana Moldoveanu (2024)

This article represents necessary research, adopting an interdisciplinary approach and a combinationofmethodologies, inordertobetter describe the evolution of the physical andmechanical characteristics of mortars. This was done employingmodernmet

23-06-2024
Uji Toksisitas Ekstrak Berbasis Nades dari Daun Kadamba (Mitragyna Speciosa Korth) terhadap Mencit (Mus Musculus)

Fauzan Afandi (2024)

Secara tradisional daun kadamba memiliki manfaat untuk mengatasi diare, diabetes, nyeri, rematik, asam urat dan terbukti secara ilmiah mampu sebagai antinosiseptif dan menghambat sel kanker payudara T47D, hingga saat ini para peneliti terus berus

23-06-2024
The Importance of Corporate Social Responsibility among Students in EUROPE

Mihaela Bucur (2024)

This document addresses the issue of awareness and involvement in Corporate Social Responsibility (CSR) by students from all over Europe. The purpose of the document is to investigate the involvement and the knowledge of students in Social Respon

23-06-2024
Identifikasi Drug Related Problems Pada Pasien Congestive Heart Failure di Rumah Sakit “X” Balikpapan

Esa Wi Fatma (2024)

Gagal jantung merupakan kondisi kegagalan jantung dalam memompa darah untuk memenuhi kebutuhan jaringan. Pasien CHF umunya diberikan paling sedikit 4 jenis obat yaitu ACEI, beta bloker, diuretik dan digoxin. Akibatnya jika tidak dipertimbangan de

23-06-2024
Ways to Increase the E ciency of Production Activity through the Active Involvement of the HumanFactor

Petruta Blaga (2024)

This paper aims to present ways to streamline production by implementing methods of analysis and continuous improvement of an important company in the Romanian car market, based on technology which produces various components, especially car wiri

23-06-2024
Pengujian Maksimal Penggunaan Ulang Masker Kain dengan Berbagai Jenis Bahan Baku Masker

Eni Ayu Putri (2024)

Masker kain digunakan sebagai alat pelindung diri dari paparan partikel asing di udara, penggunaan masker kain sekaligus dapat menekan angka limbah masker medis yang meningkat belakangan ini. Masker kain pada penggunaannya perlu dicuci berulang k

23-06-2024
Making Production More E cient Using Analysis and Continuous Improvement Methods

Petruta Blaga (2024)

This paper aims to present ways to increase the e ciency of the production activity implemented at the level of an important company of the Romanian car market producing car wiring, cables for photovoltaic panels, and industrial sensors. The comp

23-06-2024
Matlab Framework for Image Processing and Feature Extraction Flexible Algorithm Design

Razvan Cazacu (2024)

Image processing and the analysis of images in order to extract relevant data is an ever-growing topic of research. Although there are numerous methods readily available, the task of image preprocessing and feature extraction requires developing

23-06-2024
Evaluasi Penggunaan Antibiotik Secara Kuantitatif dan Kualitatif pada Pasien Bedah Digestif di RSUD Abdul Wahab Sjahranie Samarinda

Enjelina Natasya Sihite (2024)

Antibiotik merupakan golongan obat yang paling sering digunakan dalam mengatasi infeksi bakteri. Pemberian resep antibiotik tinggi dan kurang bijak akan berdampak merugikan, salah satunya yaitu meningkatkan terjadinya resistensi antibiotik. Penel

23-06-2024
Evaluasi Penggunaan Obat Antiemetik pada Penderita Kanker Payudara Pasca Kemoterapi

Dhea Amanda Sabilla Fauzi (2024)

Data dari Kementerian Kesehatan Republik Indonesia tahun 2018 menunjukkan 42.100 perempuan mengalami kanker payudara. Kemoterapi menjadi terapi pilihan utama untuk mengatasi kanker. Akan tetapi, kemoterapi memiliki efek samping salah satunya yait

23-06-2024
Formulasi Sediaan Mouthwash Ekstrak Daun Sirih Hitam (Piper sp.) Terhadap Streptococcus mutans dan Candida albicans

Deschania Noor Qhorina (2024)

Sirih hitam (Piper sp.) memiliki kandungan senyawa yang berfungsi sebagai antimikroba yaitu tanin, senyawa fenolik, saponin, flavanoid, alkaloid, dan steroid yang dapat digunakan sebagai bahan aktif pembuatan mouthwash. Tujuan dari penelitian ini

23-06-2024
Skrining Fitokimia dan Uji Aktivitas Antioksidan Ekstrak Etanol Propolis Lebah Kelulut (Heterotrigona itama)

Debby Putri Mutiara Yusuf (2024)

Propolis lebah kelulut (Heterotrigona itama) merupakan salah satu produk yang dihasilkan oleh lebah berupa getah sebagai pelindung sarang lebah dari predator luar dan biasa digunakan oleh masyarakat untuk pengobatan. Jenis ini juga menghasilkan p

23-06-2024
Green Economy and Green Growth—Opportunities for Sustainable Development †

Lucretia Dogaru (2024)

Economic activities are increasingly carried out in modern conditions, a situation which is often linked to a negative impact on the environment. They have now reached such a level that they can be considered a real factor in climate formation and

23-06-2024
Pengaruh Waktu Fermentasi Bakteri Asam Laktat dari Sari Kulit Buah Naga Merah (Hylocereus Polyrhizus) Terhadap Aktivitas Bakteri Propionibacterium acne

Cindy Puspita Perdana (2024)

Fermentasi bakteri asam laktat dari sari kulit Buah Naga Merah (Hylocereus polyrhizus) menghasilkan bakteriosin yang mempunyai kemampuan menghambat pertumbuhan bakteri patogen. Tujuan penelitian ini untuk mengetahui bahwa sari kulit buah naga mer

23-06-2024
About Sustainability between Responsible Production and Consumption †

Lucretia Dogaru (2024)

The concept of sustainable production and consumption is not only a complex one, but it is also one of great topicality and importance. It aims at the use of goods and services that meets basic needs and contributes to improving people’s living

23-06-2024
Uji Aktivitas Antioksidan dan Formulasi Gel Ekstrak Etanol Daun Jeruk Nipis (Citrus aurantifolia)

Bayu Tri Andika (2024)

Daun jeruk nipis memiliki aktivitas farmakologi seperti antibakteri dan antioksidan. Tujuan penelitian ini yaitu untuk mengetahui aktivitas antioksidan dan mendapatkan formula gel terbaik dengan dari ekstrak etanol daun jeruk nipis. Ekstrak daun

23-06-2024
Research on Qualified Vocational Training Development in the Context of Digitalization †

Marius Miklos Veres (2024)

From a strategic point of view digitalizing the economy in the near future means that it’s necessary, from now on, to change the focus on digital skills because at the moment almost all jobs require some level of digital knowledge from employees.

23-06-2023
Uji Aktivitas Antibakteri Asap Cair Daun Mangga Kuweni (Mangifera odorata) terhadap Propionibacterium acnes

Bagaskara Adi Nugroho (2023)

Asap cair adalah hasil pengembunan atau pengembunan uap yang dihasilkan oleh pembakaran langsung atau tidak dari bahan yang mengandung selulosa, lignin, hemiselulosa, dan senyawa karbon lainnya. Fungsi asap cair adalah sebagai antioksidan dan ant

23-06-2024
Research on Challenges and Prospects of Digital Agriculture †

Mihai Anitei (2024)

The actual pandemic context highlighted once again the huge importance of agriculture in the society and create a path to a speeded-up digitalization. As soon as the virus crisis will end, countries will start reprioritizing their values and do inv

23-06-2024
A New Light Aircraft and Its Design Method †

Marius-Ion Ghit,escu (2024)

The paper presents some aspects related to a new light aircraft that has as fields of use sports and leisure aviation. It also has a maximum capacity of two seats and a certain aerodynamic shape and which has on the wings mounted curved flaps for t

23-06-2024
Pengaruh Waktu Fermentasi Sari Kulit Buah Naga Merah (Hylocereus polyrhizus) Terhadap Total Bakteri Asam Laktat (BAL)

Aprilia Wulandari (2024)

Proses fermentasi menguraikan laktosa menjadi asam laktat dan berbagai komponen lain dengan parameter keberhasilan dilihat dari nilai pH dan Total Bakteri Asam Laktat. Penelitian ini bertujuan untuk menganalisis pengaruh lama waktu fermentasi dar

23-06-2024
Peculiarities Regarding the Reconstruction of a Broken Grooved Shaft †

Bogdan Bucur (2024)

The work remarks the peculiarities, which appeared in the reconstruction of a broken grooved shaft. The originality of the subject consists of the realization of a slotting tool, in material changing, which increased the reliability of the piece, a

23-06-2024
Uji Kualitatif Aktivitas Radikal Bebas DPPH dari Daun Penggugut (Knema pallens W.J.deWilde)

Annisa Anugrah Putri (2024)

Penggugut (Knema pallens W.J.deWilde) merupakan tanaman endemik Kalimantan yang termasuk kedalam famili Myristicaceae atau suku pala-palaan. Tanaman penggugut dapat ditemukan di habitat hutan dataran rendah, berpasir serta hutan bakau. Khasiat da

23-06-2024
Isolasi dan Karakterisasi Kitin dari Limbah Cangkang Kerang Asia (Corbicula fluminea)

Ameilia Rachmadianty (2024)

Senyawa kitin merupakan senyawa yang dapat ditemukan dari berbagai macam hewan golongan Crustaceae, contohnya seperti kepiting, udang, dan kerang. Tujuan dari penelitian ini ialah untuk mengetahui kandungan kitin dan karakteristik kitin dari limb

23-06-2024
Formulasi dan Uji Aktivitas Gel Anti Jerawat Ekstrak Etanol Daun Belimbing Wuluh (Averrhoa bilimbi Linn)

Akhmad Ifda Hanip (2024)

Averrhoa bilimbi Linn merupakan tanaman yang dimanfaatkan masyarakat setempat sebagai obat gatal dan jerawat. Kandungan metabolit sekunder ekstrak etanol daun belimbing wuluh (Averrhoa bilimbi Linn) dapat menghambat pertumbuhan bakteri jerawat. T

23-06-2024
English for Specific Purposes in the Context of the Shifting Educational Paradigm Triggered by Industry 4.0 †

Dana Rus (2024)

The paper proposes a model for a prospective approach to the study of the English language for engineering students. This model is influenced and shaped by the consideration of the necessity of educating engineering students for the realities of In

23-06-2024
Uji Aktivitas Antibakteri Ekstrak Kombinasi Umbi Bawang Tiwai dan Kulit Buah Lemon Terhadap Pertumbuhan Staphylococcus aureus dan Escherichia coli

Adinda Niti Meilaningrum (2024)

Bawang tiwai (Eleutherine americana (Aubl.) Merr) merupakan tanaman yang mengandung beberapa golongan metabolit sekunder salah satunya yaitu golongan alkaloid. Kulit buah lemon (Citrus limon) merupakan tanaman yang mengandung minyak atsiri lebih

23-06-2024
Studies on the Use of ISO 7730 in Romanian Companies †

Mihaela Bucur (2024)

This paper aims to identify how the ISO 7730 Standard is perceived by manufacturing companies in Romanian industry. This paper aims to integrate the details of the ISO 7730 Standard into the research related to the level of comfort in manufacturing

23-06-2024
Formulasi dan Uji Mutu Fisik Sediaan Sabun Padat Ekstrak Kulit Bawang Merah (Allium cepa L)

Adelya Youan Nurdiana (2024)

Bawang merah merupakan salah satu dari sekian banyak jenis tanaman yang tersedia di Indonesia. Bawang merah termasuk tanaman semusim yang dapat tumbuh di dataran tinggi maupun dataran rendah. Dalam pemanfaatannya bawang merah menghasilkan limbah

23-06-2024
Penerapan Game-Based Retrospective Starfish pada Proses Scrum: Studi Kasus pada Pengembangan Aplikasi Zikirin

Nabil Raihan Alfarizi (2024)

Tim pengembang aplikasi Zikirin menggunakan metode manajemen pengembangan perangkat lunak Scrum, tetapi masih menggunakan metode sprint retrospective dengan menjawab pertanyaan “Apa yang sudah berjalan dengan baik?” dan “Apa yang harus di-i

23-06-2024
Pembelajaran Daring Matematika Masa Pandemi Covid-19 di Jurusan Teknik Sipil Politeknik Negeri Malang

Mutia Lina Dewi (2024)

Covid-19 telah melanda dunia, korban semakin bertambah bahkan ada varian baru Omicron yang katanya lebih berbahaya. Masyarakat harus waspada, dunia pendidikan kembali pembelajaran daring. Masalahnya adalah apakah pembelajaran telah optimal? Dosen

23-06-2024
Faktor-faktor yang Mempengaruhi Kepatuhan Penggunaan Antibiotika oleh Pasien Rawat Jalan di Rumah Sakit Kebumen, Jawa Tengah

Muhammad Muhlis (2024)

Penggunaan antibiotika yang tidak tepat dapat menyebabkan terjadinya resistensi antibiotika. Keberhasilan terapi antibiotika dapat dipengaruhi oleh kepatuhan pasien dalam menggunakan obat. Tujuan penelitian yaitu untuk mengetahui faktor apa saja

23-06-2024
Penggunaan Machine Learning Dalam Klasifikasi Bahasa Isyarat BISINDO Menggunakan Kamera

Nico Alexander (2024)

Bahasa isyarat digunakan untuk berkomunikasi antara penyandang tunarungu dan tunawicara dengan pendengar. Permasalahan yang ada ialah bahasa isyarat jarang dipahami oleh masyarakat pada umumnya, sedangkan biaya penerjemah bahasa isyarat pada umum

23-06-2024
Gender Inequality in “The Chrysanthemums” by John Steinbeck

Indah Damayanti (2024)

This paper deals with Steinbeck`s classic short story “The Chrysanthemums,” discussing about the conflict Elisa Allen, the female protagonist faces to enhance her role as a woman in a modern society and about her attempt to gain social approv

23-06-2024
Humor Translation Accuracy in Indonesian Subtitle of Kung-Fu School Movie

Joice Yulinda Luke (2024)

This study focused on investigating the accuracy of the translation of humour in Indonesian subtitle from Kung-Fu School movie. The aims of this research were: 1) to identify the types of humour in KungFu School movie, 2) to identify the strategy

23-06-2024
Pengembangan Perangkat Penggerak Kursor bagi Tunadaksa Berbasis Wireless dengan Konektivitas Sinyal Radio dan Bluetooth

Yoga Cahyo Utomo (2024)

Penyandang disabilitas di Indonesia berdasarkan data Badan Pusat Statistik (BPS) tahun 2020 berjumlah 22,5 juta jiwa atau sekitar 5?ri jumlah penduduk Indonesia dan dari 22,5 juta penyandang disabilitas terdapat 17,74 juta yang bekerja. Pada peru

23-06-2024
Studi Klasifikasi dengan KNN dan ANN Pada Sarung Tangan Penerjemah Angka dan Alfabet Bahasa Isyarat SIBI

Kevin Christopher Wungow (2024)

Penyandang disabilitas di Indonesia khususnya pada jenis disabilitas tunawicara dan tunarungu pada tahun 2018, yaitu 0,15% untuk tuna wicara dan 0,11% untuk tuna rungu dari total masyarakat Indonesia. Berdasarkan jumlah penyandang tunawicara dan

23-06-2024
Perancangan Aplikasi Realtime Berbasis Desktop dengan Sensor IMU pada Klasifikasi Gerakan Semaphore Menggunakan Metode CNN

Tobias Nagata Budimartono (2024)

Semaphore merupakan komunikasi nonverbal yang menggunakan bendera sebagai sarana penyampaiannya. Informasi disampaikan melalui formasi bendera yang terdiri dari huruf, angka, dan simbol. Tujuan dari penelitian ini adalah untuk membuat aplikasi be

23-06-2024
Analisis Frekuensi pada Gamolan Pekhing Menggunakan Algoritma Fast Fourier Transform

I Putu Bayu Eka Pratama (2024)

Alat musik tradisional selalu menjadi ciri khas suatu daerah dalam memperkenalkan kebudayaan suatu daerah kepada khalayak luas. Dengan setiap daerah yang mempunyai alat musik khasnya masing masing, masyarakat dapat mengetahui dari mana alat musik

23-06-2024
Hubungan Intensitas Statin dengan Keterulangan Stroke

Martanty Aditya (2024)

Setiap tahun angka terjadi peningkatan angka kejadian stroke. Salah satu terapi yang direkomendasikan adalah penggunaan statin dengan efek pleiotropik dalam upaya mengurangi resiko mortalitas dan keterulangan stroke. Tujuan penelitian ini adalah

23-06-2024
Pemahaman Suku Tengger Terkait Budaya Tolak Bala Sebagai Upaya Pencegahan COVID-19

Sintia Dina Pranata (2024)

COVID-19 merupakan suatu penyakit yang disebabkan oleh virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) termasuk dalam kelas virus Ribo Nucleid Acid (RNA) bersel tunggal yang termasuk dalam ordo Nidoviral dapat ditularkan melalu

23-06-2024
Efektivitas Terapi Penggunaan Kombinasi Antivirus dan Antikoagulan pada Pasien COVID-19 di RSUD dr. Saiful Anwar Malang

Ega Malia Jiska (2024)

Covid 19 merupakan penyakit menular yang disebabkan oleh virus corona. Penyakit ini sedang menjadi wabah di seluruh dunia. Penggunaan obat pada pasien untuk menangani Covid 19 masih beragam di seluruh dunia Berbagai jenis obat digunakan untuk men

23-06-2024
Analisis Usability Testing Pada Situs Web Dinas Kominfosanti Kabupaten Buleleng

Agastia Maulana Akbar (2024)

Perkembangan teknologi yang semakin pesat membuat manusia sebagai penggunanya menginginkan untuk dapat memperoleh informasi terbaru yang lengkap. Dinas Komunikasi, Informatika, Persandian, dan Statistik (KOMINFOSANTI) Kabupaten Buleleng telah men

23-06-2024
Penerapan Usability Testing sebagai Alat Evaluasi Aplikasi Android ARInBa (Augmented Reality Instrumen Musik Bali)

Gede Agung Aji Andar Sakti (2024)

Aplikasi tidak hanya dinilai dari fungsionalitasnya saja, namun juga dinilai dari apakah user nyaman menggunakannya atau tidak. Untuk mengetahui apakah aplikasi dapat dikatakan user friendly dapat dilakukan dengan cara melakukan evaluasi dengan m

23-06-2024
Identifikasi Dhapur Keris dengan Metode Convolutional Neural Network (CNN)

Lalu Muhamad Waisul Kuroni (2024)

Indonesia merupakan negara yang memiliki kekayaan budaya yang beraneka ragam. Keris merupakan salah satu warisan budaya Indonesia yang memiliki nilai adiluhur, tersebar hampir di seluruh wilayah Indonesia. Nilai seni keris terletak pada bentuk uk

23-06-2024
Analisis Resiko Celah Keamanan Website E-Commerce Berbasis Content Management System (CMS) Wordpress Menggunakan Vulnerability Scanning (Studi Kasus: beekella.com)

Putu Bayu Baskara (2024)

Dengan adanya perkembangan teknologi didunia bisnis, saat ini e-commerce telah menjadi media dalam membantu pelaku bisnis menjalankan usahanya. Salah satunya adalah beekella.com yang merupakan e-commerce berbasis website yang menyediakan produk-p

23-06-2024
Analisis Usability Testing pada Website Desa Petandakan

Al Habib Muhammad (2024)

Informasi adalah hasil pengolahan data dalam berbagai bentuk yang berarti penting bagi penerimanya. Website http://petandakan-buleleng.desa.id/ yang merupakan website dari Pemerintahan Desa Petandakan menjadi sumber informasi bagi masyarakat Desa

23-06-2024
Perancangan Rule Base Alih Aksara Bali menjadi Huruf Latin pada Naskah Kakawin Sardula Wikridita

I Made Arya Dwisada (2024)

Aksara Bali merupakan salah satu warisan budaya Indonesia yang masih dilestarikan dan berkembang saat ini. Aksara bali berkembang beriringan dengan perkembangan Bahasa Bali di wilayah pulau Bali, dalam penggunaannya aksara Bali biasa digunakan da

23-06-2024
Implementation of Content-Based Instruction Using Animation Technology to Boost English Literacy in Kampus Mengajar Program

Monica Ayu Rishma (2024)

English literacy is an important life skill that uses reading and writing competence as essential skills in this global era. To improve students’ literacy, students should understand the language first. Nowadays, Indonesia is a widespread probl

23-06-2024
Studi Persepsi Siswa Tentang Komunikasi Kolaborasi Kelompok dalam Merdeka Belajar Kampus Merdeka

Malikhatul Lailiyah (2024)

Studi menekankan bahwa kolaborasi tetap menjadi bagian penting dari belajar dan bekerja di era Merdeka Belajar Kampus Merdeka. Penelitian ini bertujuan untuk menganalisa persepsi mahasiswa terhadap kerjasama kelompok dalam proses pembelajaran onl

23-06-2024
Implementasi One Time Password dengan Metode Advanced Encryption Standard

Oesman Hendra Kelana (2024)

Teknologi yang terus berkembang membutuhkan tingkat keamanan yang tinggi, terutama dalam menjaga password. Untuk mengatasi password yang harus diubah dalam jangka waktu tertentu, digunakanlah One-Time Password (OTP). OTP sudah berhasil diimplemen

23-06-2024
Identity and Desire in John Steinbeck’s “The Harness” (1938)

Indah Damayanti (2024)

Emma is portrayed in the nuptial relationship which situates her to be conditional upon her husband power. She seemingly portrayed as a stereotype figure of a married woman. In fact, the closely reading gives us another insight of Emma where we ca

23-06-2024
Klugee: Web-Based Application for Teaching Mathematics in English to Indonesian Elementary School Students

Bebasari Amiroh (2024)

Despite the advancement of digital technology, there is no application specializing in teaching mathematics in English for Indonesian elementary school learners. During the pandemic, teachers need online teaching media to assist them when teachin

23-06-2024
Kepercayaan Diri Siswa Dan Pengaruhnya Terhadap Keterampilan Berbicara Bahasa Inggris

Adhityo Kuncoro (2024)

Penelitian ini dilakukan untuk mengetahui kepercayaan diri siswa serta pengaruhnya terhadap keterampilan berbicara bahasa Inggris mereka. Penelitian yang menggunakan metode survey ini dilaksanan di Universitas Indraprasta PGRI, dengan 40 responde

23-06-2024
Analisis Teknik dan Metode Penerjemahan Al-Qur’an dan Terjemahannya versi Kementerian Agama dalam Ayat-ayat Khawatim Al-Suwar

M. Fahri Andrianto (2024)

Penelitian ini bertujuan untuk mengetahui teknik penerjemahan serta metode penerjemahan AlQur’an dan terjemahannya versi Kementerian Agama RI edisi penyempurnaan 2019 dalam ayat-ayat Khawatim al-Suwar. Untuk mengumpulkan data dilakukan observasi

23-06-2024
Customer Segmentation berdasarkan Usia, Jumlah Kredit dan Lama Kredit Nasabah di Bank XYZ menggunakan Model K-Means Clustering

Moch Rizky Wijaya (2024)

Pelanggan internet banking tumbuh sangat cepat. Segmentasi nasabah dapat diterapkan berdasarkan data internet banking. Clustering adalah teknik data mining tanpa pengawasan yang dapat digunakan untuk segmentasi pelanggan. Penelitian ini membangun

23-06-2024
Prototipe Aplikasi SiMaRCo (System Material Request Control) dalam Mendukung Pengendalian Persediaan Pada PT. Angkasa Pura Solusi

Oleh Soleh (2024)

Keberhasilan suatu perusahaan bisa dimulai dari baiknya sistem permintaan peralatan yang ada diperusahaan tersebut. Pengendalian permintaan peralatan perlu diperhatikan oleh perusahaan karena sangat menentukan kelancaran kegiatan operasional dalam

23-06-2024
Rancang Bangun Perangkat Keras Penunjuk Menggunakan Lengan Atas Dengan Konektivitas Bluetooth

Yusuf Giovanno (2024)

Perangkat penunjuk memberikan bantuan dalam pengoperasian komputer. Perancangan perangkat mouse menggunakan lengan atas bertujuan untuk membantu penyandang tunadaksa untuk mengoperasikan komputer dengan lebih baik. Prototipe mouse perlu dilengkap

23-06-2024
Deteksi Objek pada Film Menggunakan Yolo Object Detector dan K-Nearest Neighbor

Windra Swastika (2024)

Peran film sebagai industri budaya merupakan salah satu faktor yang dianggap penting bagi Indonesia. Film harus benar–benar diperhatikan dan dilindungi agar tidak berbalik menjadi pengaruh negatif yang tidak sesuai dan mengakibatkan kemunduran

23-06-2024
Sistem Informasi Manajemen pada Toko Bangunan (Studi Kasus: TB Al-haidar Kabupaten Malang)

Mayank Angelin (2024)

Toko Bangunan Al-haidar merupakan supermarket bahan bangunan yang menyediakan bahan bangunan seperti besi, galvalum, aluminium, alat-alat kelistrikan, alat-alat pertukangan, dan lain-lain. Semakin meningkatnya perkembangan TB Al-haidar sekarang i

23-06-2024
Pengembangan Sensor Kimia Deteksi Albumin dalam Urin untuk Penyakit Gagal Ginjal Berbasis Cobalt (Co)

Chresiani Destianita Yoedistira (2024)

Penyakit PGK (Penyakit Gagal Ginjal), protein yang hilang melalui urin dapat menyebabkan penurunan kadar albumin atau hipoalbuminemia. Keluarnya albumin melalui urin disebabkan karena adanya penurunan protein yang keluar kedalam filtrat glomerulu

23-06-2024
Pengaruh Konsumsi Tablet Tambah Darah Terhadap Proses Persalinan dan Kadar Hemoglobin pada Ibu Hamil

Martanty Aditya (2024)

Anemia pada kehamilan dapat menyebabkan dekompensasi kordis, persalinan lambat, keguguran, prematur, syok infeksi dan menyumbang meningkatkatnya Angka Kematian Ibu (AKI). Salah satu program pemerintah untuk menurunkan anemia yaitu dengan pemberia

23-06-2024
Pemanfaatan Arang Kulit Kopi Robusta Sebagai Adsorben Penurunan Kadar Amonia Pada Limbah Cair Industri Tahu

Mochammad Ersad (2024)

Kopi robusta adalah salah satu jenis kopi yang banyak ditanam di Indonesia dengan presentasi 80% sedangkan 20% petani menanam jenis kopi arabika. Salah satu limbah yang dapat dimanfaatkan ialah kulit kopi. Kulit kopi robusta mengandung 15-43% sel

23-06-2024
Uji Efektivitas Minyak Atsiri Jeruk Nipis (Citrus Aurantiifolia) Sebagai Larvasida Nyamuk Aedes Aegypti

Kamiel Roesman Bachtiar (2024)

Berbagai jenis tanaman di Indonesia telah diketahui mengandung senyawa bioaktif yang dapat dimanfaatkan sebagai biopestisida. Salah satumya adalah penggunaan minyak atsiri jeruk nipis yang mengandung limonoida yang dapat berfungsi sebagai larvasi

23-06-2024
Pengaruh Segmen Lunak Terhadap Daya Penstabilan Struktur Poliuretan Termosetting Elastomer Berbasis HTPB

Afni Restasari (2024)

Poliuretan termosetting elastomer berbasis Hydroxyl-terminated polybutadiene (HTPB) merupakan polimer dengan performa yang unggul. Sifat mekaniknya dipengaruhi oleh segmen lunak yang berasal dari rantai hidrokarbon dari HTPB. Dalam penelitian ini

23-06-2024
Terapi Bekam (Hijamah) dalam Perspektif Islam dan Medis

Hakmi Hidayat (2024)

Umat muslim memiliki kitab suci Al-Quran dan hadis sebagai sumber hukum yang utama dalam berbagai permasalahan termasuk kesehatan. Salah satu terapi pengobatan yang disebutkan dalam Al-Qur’an dan hadis adalah bekam yakni suatu proses mengeluark

23-06-2024
Kandungan Buah Delima (Punica granatum L.) dalam Perspektif Al-Qur'an, Sunnah, dan Sains

Sugeng Ali Mansur (2024)

Delima menjadi salah satu dari sekian buah yang disebutkan Allah Swt. dalam al-quran. Yakni Q.S. AlAn’am ayat 99 dan Q.S. Ar-Rahman ayat 68, dengan istilah Al-rumman (bahasa Arab). Buah Delima menjadi istimewa lantaran merupakan salah satu buah s

23-06-2024
The Benefits of Removing Dirty Blood with Traditional Cupping Treatment

Muhammad Amiruddin (2024)

In daily life, Muslims are ordered to behave by the teachings in the Al-Quran and the sunnah of the Prophet Muhammad, including regarding health. In the world of health, it is known that alternative medicine in the style of Rasulullah SAW is know

23-06-2024
Implementation of Ruqyah as an Alternative to Islamic Medicine in Indonesia

Kartika Ratnasari (2024)

One of the religious therapies in the life of Muslims is ruqyah. Ruqyah is a prayer accompanied by dhikr to Allah Almighty by reciting the holy verses of the Quran and hadith. Ruqyah is used to cure mental disorders, physical illnesses, and other

23-06-2024
Acetylation of Emodin and Cytotoxic Activity Effect Against HepG2 Cell Lines

Firdayani (2024)

Emodin (1,3,8-trihydroxy-6-methyl-9,10-anthraquinone) is an anthraquinone bioactive compound used as a lead compound because it exhibits potential anticancer properties. Structural modifications were made at the C3 position and its relationship t

23-06-2024
Determination of Quercetin in Extracts and Herbal Products of Phyllanthus niruri by TLC Densitometry Method

Bachtiar Rifai Pratita Ihsan (2024)

Phyllanthus niruri has many pharmacological activities such as antioxidant, anti-inflammatory and anticancer. Phyllanthus niruri has been widely developed from extracts into herbal products. The flavonoid quercetin became an analytical marker com

23-06-2024
Analysis of Antidiabetic Potential of Palmitic Acid Compounds Through In Silico Activation

Ardellya Elfidaa Salsabila (2024)

Diabetes Mellitus is a condition where the body's sugar level exceeds the blood's normal limit. Type 2 Diabetes Mellitus is the most common type of diabetes and is a chronic disease caused by insulin resistance and beta-cell dysfunction, resultin

23-06-2024
Scoping Review: Analysis of Alcohol Levels in Food and Beverages Using Gas Chromatography

Suryanto (2024)

Islamic teachings explain that food or beverage should not be consumed with more than 0.5% alcohol because it is categorized as khamr, which is unlawful. In determining the levels of foods or beverages that contain alcohol, one of which is the ga

23-06-2024
Antineuroinflammatory Properties of Compounds from Ethyl Acetate Fraction of Marsilea crenata C. Presl. Against Toll-Like Receptor 2 (3A7B) In Silico

Burhan Maarif (2024)

Parkinson's disease (PD) can be triggered by overactive TLR2 due to ?-synuclein abnormalities and aggregation. Marsilea crenata C. Presl. leaves inhibit neuroinflammatory progression. This study aimed to predict the antineuroinflammatory activity

23-06-2024
The Effect of Schleichera oleosa L. on HbA1c Levels in Alloxan-Induced Rats

Akbar Awaluddin (2024)

Diabetes mellitus is a chronic disease that occurs due to the failure of the pancreas to produce sufficient insulin, or the body cannot use the insulin it makes effectively. The HbA1c (glycated hemoglobin) levels show an alteration in blood gluco

23-06-2024
AKTIVITAS SIRUP IMUNOMODULATOR “X” MEREDAM RADIKAL BEBAS 2,2’-DIPHENYL-1- PICRYLHYDRAZIL

Ichwan Ridwan Rais (2024)

Oksidasi adalah proses reaksi perpindahan elektron dari suatu substansi ke senyawa pengoksidasi dan menghasilkan radikal bebas. Proses ini dapat memicu terjadinya kerusakan sel. Antioksidan adalah senyawa yang dapat menghambat proses oksidasi. Si

23-06-2024
THE EFFECTIVENESS OF AMLODIPINE AND NIFEDIPIN ON HYPERTENSION OUTPATIENTS AT PUBLIC HEALTH CENTRE

Alfian Aji Wicaksono (2024)

Effectiveness is the extent to which a drug can achieve the desired effect in clinical practice, in this case, to achieve an effect in lowering systolic and diastolic blood pressure to a standard value. This study aims to determine the effectiven

23-06-2024
UJI STABILITAS FISIK, KIMIA DAN MIKROBIOLOGI TABLET KUNYAH EKSTRAK ETANOL SPIRULINA (Spirulina platensis)

Siti Fatmawati Fatimah (2024)

Tingginya kandungan ß-karoten di Spirulina platensis dapat mengatasi defisiensi vitamin A sehingga diinovasikan sebagai tablet kunyah. Tujuan penelitian adalah mengetahui pengaruh lama penyimpanan tablet terhadap parameter uji stabilitas, jumlah

23-06-2024
KADAR FLAVONOID TOTAL DAN AKTIVITAS ANTIOKSIDAN FRAKSI METANOL EKSTRAK ETANOL DAUN GAMBIR (Uncaria gambir Roxb)

Rahayu Mayaringtyas (2024)

Gambir merupakan tanaman yang mengandung senyawa antioksidan yang disebut flavonoid. Beberapa penelitian menunjukkan bahwa flavonoid merupakan senyawa yang memiliki kemampuan untuk melawan radikal bebas. Oleh karena itu, penelitian ini diharapkan

23-06-2024
MOLECULAR DOCKING OF XIAMYCIN DERIVATIVES ON RNA-DEPENDENT RNA POLYMERASE AS A SARS-COV-2 VIRUS REPLICATION INHIBITOR

Hamnah Al Atsariyah (2024)

Xiamycin is a pentacyclic indolosesquiterpenoid derived from mangrove endophytes was studied in vitro to inhibit the replication of porcine epidemic diarrhea virus and human immunodeficiency virus. This study aimed to examine the potential pharma

23-06-2024
ANALISIS MERKURI PADA BLEACHING CREAM YANG DIJUAL SECARA ONLINE DAN TIDAK MEMILIKI IZIN EDAR DARI BPOM

Dian Prasasti (2024)

Seiring perkembangan zaman banyak wanita yang menggunakan produk kosmetik krim pemutih untuk mendapatkan kulit yang putih secara instan. Hal ini dimanfaatkan oleh produsen yang tidak bertanggung jawab memasukkan bahan berbahaya seperti merkuri ke

23-06-2024
TINGKAT PENGETAHUAN PENGGUNAAN OBAT ANALGETIK ANTIPIRETIK UNTUK SWAMEDIKASI DI KECAMATAN PANCALANG KABUPATEN KUNINGAN

Muhammad Muhlis (2024)

Swamedikasi menurut World Health Organization (WHO) yaitu upaya pengobatan sendiri yang dilakukan secara mandiri guna melindungi serta mengobati dari segala keluhan penyakit. Obat analgetik antipiretik yang biasa digunakan oleh masyarakat secara

23-06-2024
KARAKTERISTIK KRIM EKSTRAK ETANOL DAUN SALAM (Syzygium polyanthum W.) terhadap Staphylococcus aureus

Lina Widiyastuti (2024)

Ekstrak etanol daun salam memiliki kandungan tanin, flavonoid, dan minyak atsiri yang berkhasiat sebagai antibakteri. Penelitian dilakukan untuk mengetahui efektifitas krim ekstrak etanol daun salam sebagai antibakteri terhadap Staphylococcus aur

23-06-2024
AKTIVITAS ANTIOKSIDAN EKSTRAK ETANOL 96?N FRAKSI ETIL ASETAT DAUN PEPAYA

Drian Aulia Arif Wicaksono (2024)

Pepaya merupakan tumbuhan tropis yang umum ditemukan di wilayah Indonesia. Daun pepaya diketahui memiliki kandungan senyawa flavonoid. Senyawa flavonoid diteliti memiliki aktivitas sebagai antioksidan. Tujuan penelitian ini adalah untuk membandin

23-06-2024
OPTIMASI FORMULA GEL EKSTRAK DAUN PEGAGAN (Centella asiatica (L.) Urban) DENGAN KOMBINASI GELLING AGENT KARBOPOL 940 DAN HPMC MENGGUNAKAN METODE FACTORIAL DESIGN

Bethari Rudhinindya Yoscar (2024)

Ekstrak daun pegagan telah terbukti bermanfaat sebagai antibakteri dan antiinflamasi. Untuk memudahkan dalam penggunaanya, ekstrak tersebut dapat dibuat dalam bentuk sediaan gel menggunakan kombinasi gelling agent karbopol 940 dan hidroksipropil

23-06-2024
PENGARUH KONSENTRASI BIJI KEFIR DAN WAKTU FERMENTASI TERHADAP AKTIVITAS ANTIBAKTERI KEFIR SUSU SAPI DAN KEFIR SUSU KACANG TANAH PADA BAKTERI Shigella dysenteriae

Nanik Sulistyani (2024)

Kefir dapat dibuat dari susu hewani maupun dari bahan nabati. Susu kacang tanah mengandung protein yang hampir setara dengan kandungan protein susu hewani. Tujuan penelitian ini adalah untuk mengetahui organoleptis kefir susu sapi dan kefir susu ka

23-06-2024
KAJIAN LITERATUR: PENGETAHUAN, SIKAP DAN PERILAKU TERHADAP COVID-19 DI MASYARAKAT INDONESIA

Ridwansyah, MT (2024)

Jumlah kasus COVID-19 yang dikonfirmasi berkurang 15% secara global. Di Indonesia, jumlah kasus terkonfirmasi, kesembuhan, dan kematian meningkat. Edukasi tentang COVID-19 melalui berbagai media sudah diberikan kepada masyarakat, sehingga lebih

23-06-2024
FORMULASI DAN EVALUASI KRIM EKSTRAK ETANOL BERAS MERAH (Oryza nivara L.)

Nadif Tuzairoh (2024)

Antiaging adalah sediaan untuk menghambat proses degeneratif dan timbulnya tanda penuaan kulit. Beras merah (Oryza nivara L.) memiliki kandungan antosianin yang bertindak sebagai antioksidan alami efektif untuk mencegah penuaan dini. Tujuan pen

23-06-2024
HUBUNGAN FAKTOR DEMOGRAFI DENGAN PERSEPSI, SIKAP DAN PERILAKU PENCEGAHAN COVID-19 PADA PASIEN DIABETES MELLITUS DI APOTEK RAMADHAN YOGYAKARTA

Nurbaizura Putri (2024)

Penderita diabetes mellitus (DM) merupakan salah satu populasi rentan terinfeksi COVID19. Upaya pencegahan terus digalakkan untuk menekan prevalensi COVID-19. Penelitian ini dilakukan untuk mengetahui hubungan faktor demografi dengan persepsi, sika

23-06-2024
STUDI LITERATUR: EVALUASI PENGGUNAAN OBAT INDOMETHACIN PADA PASIEN GOUT

Youlan Niesa (2024)

Terapi farmakologi untuk mengatasi penyakit gout dengan mengurangi nyeri dapat obat Indomethacin, dimana obat Indomethacin termasuk obat golongan Non Steroidal Anti Inflammatory Drug (NSAID). Tujuan penelitian ini dilakukan yaitu untuk mengetahui

23-06-2024
EFEKTIVITAS PUTIH TELUR AYAM NEGERI TERHADAP PENYEMBUHAN LUKA SAYAT PADA MENCIT

Wahyu Widyaningsih (2024)

Putih telur mengandung protein yang dapat menyembuhkan luka dengan membentuk jaringan baru dan mempercepat pemulihan jaringan sel tubuh yang rusak. Penelitian ini bertujuan untuk mengetahui efektivitas gel putih telur ayam negeri pada terhadap

23-06-2024
STUDI ETNOMEDISIN PADA MASYARAKAT DI KELURAHAN SECANG, DESA DONOMULYO, PUCANG, KALIJOSO DAN PANCURANMAS KECAMATAN SECANG KABUPATEN MAGELANG

Nahdliyah Umma (2024)

Mayoritas penduduk Indonesia masih menggunakan sistem pengobatan secara tradisional. Obat tradisional merupakan obat turun-temurun yang digunakan oleh masyarakat untuk mengobati beberapa penyakit tertentu dan dapat diperoleh secara bebas di alam.

23-06-2024
AKTIVITAS PENURUNAN TEKANAN DARAH JAMU “X” PADA TIKUS WISTAR JANTAN

Andaru Adiwignya Gunawan (2024)

Terapi hipertensi dapat dilakukan melalui terapi farmakologi maupun non farmakologi. Contoh terapi non farmakologi hipertensi adalah penggunaan seduhan Jamu “X” yang merupakan ramuan empiris dari Banjarnegara. Penelitian ini bertujuan untuk m

23-06-2024
PERESEPAN VITAMIN PADA PASIEN WANITA HAMIL SEBELUM DAN SELAMA PANDEMI COVID-19

Shohifa Hafida (2024)

Corona Virus Disease 2019 (COVID-19) adalah penyakit menular yang disebabkan oleh Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2. Wanita hamil dianggap sebagai kelompok populasi khusus karena kerentanan mereka terhadap beberapa penya

23-06-2024
REVIEW HUBUNGAN POLIMORFISME GEN CYP2C19 DENGAN RESISTENSI CLOPIDOGREL PADA PASIEN KARDIOVASKULAR DAN STROKE

Viren Ramadhan (2024)

Obat antiplatelet mempunyai respon variabilitas pada penyakit kardiovaskular, terutama clopidogrel. Sejumlah besar penelitian telah diterbitkan dalam topik ini. Penelitian ini bertujuan untuk mengkaji beberapa artikel penelitian tentang hubungan

23-06-2024
ANALISIS KADAR VITAMIN C PADA BUAH PEPAYA (Carica papaya L.) DENGAN METODE SPEKTROFOTOMETRI UV-VIS

Bintari Tri Sukoharjanti (2024)

Latar Belakang: pepaya merupakan tanaman yang banyak ditemukan di Indonesia, berasa manis serta banyak mengandung vitamin C yang diperlukan tubuh manusia. Buah pepaya dapat dikonsumsi untuk memenuhi kebutuhan vitamin C harian, dapat dimanfaatkan

23-06-2024
UJI ANTIBAKTERI EKSTRAK ETANOL 70?UN PEPAYA (Carica papaya L.) TERHADAP BAKTERI Escherichia coli

Hasriyani (2024)

Latar Belakang : Penyakit-penyakit yang disebabkan oleh Escherichia coli menjadi ancaman terhadap kesehatan individu dan masyarakat. Escherichia coli normalnya merupakan organisme komensal dalam saluran cerna hewan dan manusia namun dapat menjadi

23-06-2024
ANALISIS FAKTOR YANG BERPENGARUH DALAM PENGGUNAAN ANTIBIOTIK SECARA BEBAS DI MASYARAKAT KECAMATAN JEKULO KABUPATEN KUDUS

Kharisma Aprilita Rosyidah (2024)

Frekuensi penggunaan antibiotik yang tinggi merupakan salah satu faktor pemicu terjadinya resistensi mikroba, yang menjadi masalah kesehatan masyarakat yang utama di banyak negara. Terjadinya resistensi akibat penggunaan antibiotik yang tidak tep

23-06-2024
PENGARUH JENIS PELARUT TERHADAP HASIL EKSTRAKSI DAUN LIDAH MERTUA (Sansevieria trifasciata)

Gina Septiani Agustien (2024)

Flavonoid dalam daun lidah mertua termasuk senyawa potensial sebagai antioksidan. Proses ekstraksi maserasi pada umumnya menggunakan pelarut organik untuk mendapatkan rendemen perlu optimasi jenis pelarut. Tujuan dari penelitian ini yaitu untuk m

23-06-2024
PENGETAHUAN DAN KEPATUHAN MINUM OBAT PASIEN TUBERKULOSIS PARU DI PUSKESMAS KOTA YOGYAKARTA

Nabila Dwi Febrianti (2024)

Latar Belakang. Tuberkulosis (TB) masih merupakan penyakit infeksi dengan beban tertinggi di dunia. Pada tahun 2019, Indonesia merupakan Negara dengan peringkat ketiga beban tertinggi akibat penyakit TB di dunia. Pemerintah Indonesia telah mengus

23-06-2024
ANALISIS BIAYA MEDIS LANGSUNG PASIEN HEPATITIS B DI RUMAH SAKIT PKU MUHAMMADIYAH GAMPING YOGYAKARTA

Alfia Husna (2024)

Hepatitis B adalah suatu penyakit inflamasi hepar yang disebabkan oleh hepatotropik virus Hepatitis B. Indonesia adalah salah satu negara dengan tingkat endemisitas tinggi. Penelitian ini bertujuan untuk mengetahui gambaran penggunaan obat terban

23-06-2024
AKTIVITAS ANTIOKSIDAN DAN SUN PROTECTION FACTOR (SPF) EKSTRAK ETANOL KULIT BUAH DELIMA HITAM

Uswatun Chasanah (2024)

Kulit buah delima hitam (Punica granatum L) dikenal memiliki daya antioksdan yang kuat. Kandungan total senyawa fenolik dan total flavonoid golongan antosianin yang terdapat dalam kulit buah delima hitam yang lebih tinggi dibandingkan dengan kuli

23-06-2024
PENGARUH VARIASI WAKTU SONIKASI TERHADAP KADAR FLAVONOID TOTAL EKSTRAK METANOL UMBI GADUNG (Dioscorea hispida Dennst.)

Susanti (2024)

Senyawa flavonoid yang terdapat pada umbi gadung (Dioscorea hispida Dennst.) diketahui memiliki aktivitas antioksidan yang baik. Dalam beberapa penelitian sampai saat ini, maserasi merupakan cara ekstraksi umbi gadung yang umum digunakan. Keunggu

23-06-2024
SR (SURVIVAL RATE) 3 TAHUN PASIEN KANKER PARU DENGAN TERAPI GEFITINIB VERSUS ERLOTINIB PERIODE 2017-2019 DI RSUP Dr. KARIADI SEMARANG

Widia Akmasari (2024)

Kanker paru merupakan penyebab kematian tertinggi di dunia, salah satunya non-small cell lung cancer (NSCLC). NSCLC adalah penyakit kanker paru yang terdiri dari tiga subtipe utama yaitu adenokarsinoma, karsinoma paruselskuamosa, dan karsinoma pa

23-06-2024
Formulation and Clinical Evaluation of A Topical Dosage Form of Alkanna orientalis Root Extract for Management of Pressure Lesions: A Pilot Cross-Sectional Clinical Trial

Elham Lazarzareh (2024)

Background: Pressure lesions are chronic wounds causing the development of infection and inflammation into deeper structures and finally necrosis. In Persian medicine, Alkanna orientalis (Boraginaceae) has been used for centuries as a naturally de

23-06-2024
Effect of Recommended Dietary Intake versus Higher Doses of Supplemental Zinc on Iron and Copper Deficiency Anemia Among Patients with Chronic Kidney Diseases, A Double-Blinded, Randomized Clinical Trial

Zahra Nazari-Taloki (2024)

Background: Complex interplays happen in absorption and function of iron, zinc and copper. Both zinc deficiency and excess may lead to anemia. In Iran, commonly available supplements for chronic kidney disease (CKD) patients contain 25 mg-zinc (Z

23-06-2024
MicroRNA 138 Upregulation is Associated with Decreasing Levels of CCND1 Gene Expression and Promoting Cell Death in Human Prostate Cancer Cell Lines

Nasrin Haghighi-Najafabadi (2024)

Background: This research intended to discover the significance of miR-138 (microRNA 138) on the expression profile, proliferation, and the associated regulatory mechanisms in prostate cancer (PCa). Methods: Thirty-five specimens of prostate wer

23-06-2024
Investigation of the Apoptotic Effects of Mesenchymal Stem Cells on KG-1 Leukemic Cell Line

Raheleh Farahzadi (2024)

Background: Mesenchymal stem cells (MSCs) are undifferentiated cells with the ability of multipotency, pluripotency, and self-renewal. MSCs show great promise in cancer therapy due to their unique features. MSC secrete various cytokines with multif

23-06-2024
Therapeutic Effects of Co-administration of Silver Nanoparticles and Vitamin C on Vaginal Infection Caused by Group B Streptococcus

Zhale Mansoori (2024)

Background: Group B Streptococcus (GBS) is a bacterium commonly isolated from the vagina. Silver nanoparticles (SNPs) are potential antibacterial agents, and studies have shown their toxic effects. Vitamin C (VC) is an essential vitamin with a pr

23-06-2024
Mitochondrial Transplantation Attenuates Toxicity in Human Lymphocytes Caused by Clozapine and Risperidone

Abdollah Arjmand (2024)

Background: Clozapine (CLZ) and risperidone (RIS) are drugs that have the ability to disrupt mitochondrial function. Also, these drugs increase the level of free radicals. Mitochondrial dysfunction plays a role in the etiology of various diseases

23-06-2024
Cytotoxic Activity of Indonesian Pogonatum neesii Dozy from Cibodas Botanical Garden: In Silico Molecular Docking and In Vitro Evaluation

Rizky Nurdiansyah (2024)

Background: The exploration of bryophytes biodiversity in Indonesia due to its abundance and the bioactivity of its phytochemical content, such as alkaloids and polyphenols, has received increased interest. Despite some species proven to possess

23-06-2024
Biological Effects of Melatonin on Telomere Length in Breast Cancer: A Review Article

Elmira Barari (2024)

There has been increasing interest in studying the effects of dietary factors on telomere length. The telomere is a noncoding DNA sequence including “TTAGGG” at the ends of chromosomes of vertebrates. The stability of telomere length is an im

23-06-2024
The Influence of ?-Alanine Supplementation on Recovery Biomarkers in Adults: A Systematic Review and Meta-Analysis

Mahsa Mahmoudinezhad (2024)

Background: Clinical studies, investigating the effect of ?-Alanine (BA) supplementation on recovery biomarkers in physically active individuals, have generated inconsistent results. This systematic review and meta-analysis study aimed to clarify

23-06-2024
A Comprehensive Overview of Organ Inflammatory Responses: Genesis, Possible Mechanisms, and Mediators of Inflammation

Samar A. Antar (2024)

An immune system response known as inflammation can be carried on by a variety of things, such as infections, damaged cells, and noxious substances. These factors may cause acute or chronic inflammatory responses in the heart, pancreas, liver, ki

23-06-2024
Exploiting Advances in Automation and Artificial Intelligence to Find Drugs for Neglected Tropical Diseases

David Alan Winkler (2024)

Parasitic (e.g., malaria, African trypanosomiasis, leishmaniasis), bacterial (e.g., tuberculosis, leprosy), and viral diseases (e.g., rabies, Dengue fever, Chikungunya, Ebola) still kill 2.5 M people annually, and create misery and suffering

23-06-2024
Evaluation of the Anticancer, Anti-Inflammatory, and Antioxidant Properties of Various Extracts of Annona squamosa L.

Nour Awada (2024)

Background: Screening medicinal plants for their biological activities and phytochemicals is important for finding safe and potent new compounds for therapeutic use. The current investigation was conducted in extracts of Lebanese A. squamosa (lea

23-06-2024
Minoxidil and Dexamethasone Eluting Nanofiber Dressing for Cutaneous Wound Healing in Rat

Saber khozan (2024)

Background: Minoxidil is an antihypertensive agent and vasodilator which may help to promote local blood flow thus hastening the closure of excisional skin wounds. Corticosteroids may down-regulate wound healing. This work aims to develop and cha

23-06-2024
Utilizing Nanoparticle Catalyzed TMB/H2 O2 System for Determination of Aspirin in Exhaled Breath Condensate

Samineh Mohammadzadeh Abachi (2024)

Background: According to the poison center data for most countries, more than thousands of people’s exposure to aspirin or salicylate-containing products. So, this work aimed was to offer a rapid colorimetric method for monitoring aspirin conce

23-06-2024
Cardioprotective Effects of Coenzyme Q10 Supplementation on Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Amirhossein Yazdi (2024)

Background: We assessed the potential efficacy of Coenzyme Q10 (CoQ10) in patients with STsegment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (PPCI). Methods: Seventy STEMI patients who presented ?

23-06-2024
The Effects of Vitamin K2 (Menaquinone-7) on the Leptin and Adiponectin Levels in Overweight/Obese Type 2 Diabetes Patients: A Randomized Clinical Trial

Shaghayegh Adeli (2024)

Background:Type 2 diabetes mellitus (T2DM) is a prevalent disease with metabolic consequences. Lower levels of adiponectin and higher levels of leptin were reported in T2DM. This study aimed to evaluate the effect of menaquinone-7 (MK-7) supplemen

23-06-2024
Effect of Delphinium denudatum Wall. (Jadwar) on Knee Osteoarthritis: A Randomized Double-Blinded Placebo-Controlled Clinical Trial

Roghayeh Baghervand Navid (2024)

Background: Osteoarthritis (OA) is the most common disease of joints. The management of OA is challenging due to the efficacy and safety of treatments. In recent decades, traditional herbal medicines have been introduced for treatment of disease.

23-06-2024
mir-451a-5p Modulates Breast Cancer Cell Apoptosis, Migration, and Chemosensitivity to Carboplatin through the PTEN Pathway

Monireh Khordadmehr (2024)

Background: MicroRNAs (miRNAs) can play essential roles in the modulation of cancer cell growth, survival, and resistance to chemotherapy. Thus, we hypothesized that restoration of miR-451a-5p (a tumor suppressor) might affect sensitivity to chem

23-06-2024
Fucoxanthin Inhibits the Proliferation of ABCC2-Over Expressing Cisplatin-Resistance Ovarian Cancer Cells via Inducing Apoptosis

Fatemeh Valinezhad Sani (2024)

Background: The development of multidrug resistance (MDR) is a major barrier to achieving effective chemotherapy in cancer. Studies have shown that epithelial ovarian cancer initially responds to platinum-based therapy, however, the recurrent typ

23-06-2024
Recent Trends in Phytosome Nanocarriers for Improved Bioavailability and Uptake of Herbal Drugs

Vijayakumari Mahadevan Hari Priya (2024)

Phytopharmaceuticals or herbal drugs have a significant therapeutic impact on healthcare systems. Though herbal extracts and their active constituents show excellent pharmacological in vitro effects, they still have indigent in vivo biological ef

23-06-2024
Application of 3D Printing in Pharmaceutical Sciences, and Evaluation of Administration Routes for Drug-Loaded Composites

Mohamad Khatami (2024)

3D printing is a novel approach in the pharmaceutical field, but its usage has not been fully established. This method can promote drug therapy and overcome some traditional treatment challenges in different ways that are discussed in this paper.

23-06-2024
Role of Preclinical Arthritis Models for the Clinical Translation of Anti-Arthritic Therapeu

L Ronibala Singha (2024)

The overcomplicated and elusive pathophysiology with unclear etiology, have been the main driving force of the medical scientists all over the world to develop a predictive, reliable, robust and reproducible simulation model of arthritis. This re

23-06-2024
The Promotion of Antioxidant and Anti-Inflammatory Activity by Nrf2 Amplifier is A Potential Technique in Diabetic Wound Healing — A Review

Tharani Mohanasundaram (2024)

Wound healing is a complicated, organised process that includes numerous phases that connect diverse cellular events and activate several intracellular molecular pathways in injured cells and tissues. Delay in wound healing owing to high levels o

23-06-2024
Applications of Spray Freeze-drying for Formulating Bioactive Wound Powders

Shahram Emami (2024)

Chronic wounds do not heal in an expected timeline. The complications of chronic wounds make them an important issue for public health. The quality of life of patients with chronic wounds is negatively affected because of heavy exudates and u

23-06-2024
Phytochemical and Antiplasmodial Evaluation of Five Colombian Plants with Ethnopharmacological Background of Antimalarial Use

Jorge Enrique Hernández-Carvajal (2024)

Background: The study of medicinal plants has made it possible to develop products and drugs for the treatment of different diseases. Several plants in Colombia have a history of popular use for the treatment of malaria. The objective of this wor

23-06-2024
Characterization and Biological Activities of Silver Nanoparticles Synthesized Using Grewia tiliifolia Vahl Leaf Extract

Sneha Desai K. (2024)

Background: An eco-friendly approach for the synthesis of noble metal nanoparticles employing various plant extracts has become of great interest in the field of nanotechnology. In the present study, the efficacy of Grewia tiliifolia leaf extract

23-06-2024
Phytochemical Analysis and Antioxidant Activity of Eight Cultivars of Tea (Camellia sinensis) and Rapid Discrimination with FTIR Spectroscopy and Pattern Recognition Techniques

Fatemeh Yousefbeyk (2024)

Background: Tea (Camellia sinensis L.O. Kuntze) is one of the most commonly consumed beverages globally, with several beneficial health effects. The composition of leaves is affected by different factors such as climate and tea cultivar. Methods

23-06-2024
Construction and Transfer of PEI-miRNA-126/210 Polyplex into Human Umbilical Vein Endothelial Cells with Investigation of Its Effect on Islets Survival and Function

Fatemeh Sabet Sarvestani (2024)

Background: Type 1 diabetes is an autoimmune disorder characterized by the loss of pancreatic islets. Islet allotransplantation is a potentially beneficial therapeutic approach for diabetes. Islets suffer a variety of cellular insults including i

23-06-2024
Cell-Penetrating Peptide-Surface Modified Liposomes to Enhance the Intestinal Absorption of Enoxaparin

Hessam Rostamian (2024)

Background: Enoxaparin is low-molecular-weight heparin administered by subcutaneous/ intravenous injection. The oral bioavailability of enoxaparin is restricted by its low absorption through the intestine. In this study cell-penetrating peptide-su

23-06-2024
Designing a Topical Nanoliposomal Formulation of Ruxolitinib Phosphate

Atefeh Naeimifar (2024)

Background: The JAK-STAT pathway has been revealed to play a crucial role in the dysregulation of immune responses in autoimmune skin disorders. Ruxolitinib, a selective inhibitor of JAK1 and JAK2, potently suppresses cytokine signaling. Methods

23-06-2024
The Impact of Metformin on Cardiac Troponin-I and ST Resolution in Patients with ST Elevation Myocardial Infarction Undergoing Thrombolytic Therapy

Naser Aslanabadi (2024)

Background: Thrombolytic therapy is a key in the management of ST elevated myocardial infarction (STEMI). Metformin implies a series of cardioprotective effects. We aimed to investigate how pretreatment with metformin could affect cardiac troponi

23-06-2024
A Randomized, Single-blind, Comparison Trial of Beractant (BeraksurfTM) versus Poractant Alfa (Curosurf®) in the Treatment of Respiratory Distress Syndrome in Preterm Infants

Manizheh Mostafa Gharehbaghi (2024)

Background: Neonatal respiratory distress syndrome (NRDS) affects approximately up to 7% of all term newborns. This study aimed to assess the efficacy and safety of investigational beractant (BeraksurfTM, Tekzima Company) in comparison with porac

23-06-2024
Assessment of the Presence of Sas Family Genes and Their Relationship with Biofilm Formation among Clinical Staphylococcus aureus Isolates

Alka Hasani (2024)

Background: The success of Staphylococcus aureus as an important human pathogen is probably due to possession of various virulence determinants. Attachment and biofilm formation is considered the main step in any infection. The present study a

23-06-2024
The Effect of Aqueous-Alcoholic Extract of Toothbrush Tree (Salvadora persica) on the Healing of Second-Degree Skin Burns in BALB/c Mice

Mohammad Afshar (2024)

Background: Researchers have mentioned many beneficial effects for the compounds present in the toothbrush tree (Miswak) (Salvadora persica: SP); such as anti-inflammatory, antioxidant and antimicrobial activities. The current study aimed to eval

23-06-2024
The Role of Andrographis paniculata in Modulating the Immune Response in Cancer-Associated Chronic Inflammation, Angiogenesis, and Metastasis

Rengganis Ulvia (2024)

The immune system plays an essential role in cancer pathogenesis through providing an inflammatory immune response. Chronic inflammation causes tumor growth, angiogenesis, and metastasis facilitated by interactions between tumor, immune, and stro

23-06-2024
Modulation of Nrf2 by Activation of Estrogen Receptor ? as a Therapeutic Strategy to Prevent Cancer Development and Overcome Inflammation-Related Drug Resistance in Breast Cancer

Emdormi Rymbai (2024)

Despite the tremendous progress in breast cancer diagnosis and treatment, the mortality rate is expected to increase due to the emergence of drug resistance. Pro-inflammatory markers are thought to contribute to drug resistance by activation of i

23-06-2024
Determination of Benzo(?)pyrene in Infant Formula Using High Performance Liquid Chromatography and Dispersive Liquid–Liquid Microextraction

Akram Faridi (2024)

Background: Benzo(?)pyrene (BaP) is one of the most familiar polycyclic aromatic hydrocarbons (PAHs) to evaluate food safety and quality and can be present in infant formulas An analytical method for the extraction and quantification of BaP in in

23-06-2024
Synthesis, Crystal Structure and Antibacterial Activity of Cu(II) Complex with Nitrogen Donor Pyrazolyl Borate Derivatives

Behzad Soltani (2024)

Background: Pyrazolyl borate derivatives are versatile ligands that can be coordinated with transition metals and formated a variety of different coordination modes. Copper complexes are highly active in biological applications and have high bioa

23-06-2024
Solubility of Bosentan in Polyethylene Glycol 400 + Water Mixtures: Experimental and Mathematical Computations

Parisa Jafari (2024)

Background: To discover the optimal solvent amounts for using in a particular application, it is vital to achieve some useful information in regard with suitable neat or mixed solvent and drugs equilibrium solubility in them. It is known that the

23-06-2024
Sensing of Letrozole Drug by Pure and Doped Boron Nitride Nanoclusters: Density Functional Theory Calculation

Afsoon Behmanesh (2024)

Background: Letrozole is a non-steroidal drug utilized as a treatment of hormone-sensitive breast cancer. It has been shown that letrozole has harmful side effects. Therefore, it seems necessary to design a letrozole drug sensor. In this work, we

23-06-2024
Preparation and In-Vitro Evaluation of Ketoconazole-Loaded Niosome (Ketosome) for Drug Delivery to Cutaneous Candidiasis

Katayoun Morteza-Semnani (2024)

Background: Recently, niosomes are becoming popular in drug delivery. The current work aimed to investigate the characteristics, cellular safety, and antifungal activity of ketoconazoleloaded niosome (ketosome). Methods: Ultrasonic approach was e

23-06-2024
Fasudil Attenuated 6-OHDA Cytotoxicity in PC12 Cells through Inhibition of JAK/STAT and Apoptosis Pathways

Samira Barangi (2024)

Background: 6-Hydroxydopamine (6-OHDA) is widely used to induce neurotoxicity and investigate the mechanisms of Parkinson disease. 6-OHDA causes cell injury through various mechanisms including oxidative stress, inflammation and apoptosis. The se

23-06-2024
Salvurmin A and Salvurmin B, Two Ursane Triterpenoids of Salvia urmiensis Induce Apoptosis and Cell Cycle Arrest in Human Lung Carcinoma Cells

Shima Hashemi (2024)

Background: Ursane triterpenoids could be considered as novel multi-target therapeutic anticancer agents. Salvurmin A and Salvurmin B are novel cytotoxic ursane triterpenoids isolated from the aerial parts of Salvia urmiensis, an endemic plant spec

23-06-2024
Effect of Juglans regia L. Ridge on Blood Lipids in Type 2 Diabetic Patients with Dyslipidemia: A Double-blind Placebo-Controlled Randomized Clinical Trial

Mehrzad Mirshekari (2024)

Background: Dyslipidemia and diabetes mellitus are two important risk factors for coronary artery disease and stroke. Traditionally, herbal remedies like walnut were used to treat dyslipidemia. The study aimed to evaluate the effect of Juglans re

23-06-2024
Effect of A Probiotic Preparation on Gut Microbiota in Critically Ill Septic Patients Admitted to Intensive Care Unit: A Pilot Randomized Controlled Trial

Ata Mahmoodpoor (2024)

Background: Sepsis promotes severe physiologic alterations in patients, and it has been reported to induce profound changes in the gut microbial composition. The decrease of ‘health?benefiting’ microbes and the increase in dysbiosis in critic

23-06-2024
Sildenafil Blunts Lung Inflammation and Oxidative Stress in a Rat Model of Cholestasis

Mohammad Mehdi Ommati (2024)

Background: Cholestasis is a multifaceted disease that influences not only the function of the liver but also affects many other organs. In this context, cholestasis-induced lung injury is a significant clinical complication. Unfortunately, there

23-06-2024
The Application of Polymers in Fabricating 3D Printing Tablets by Fused Deposition Modeling (FDM) and The Impact on Drug Release Profile

Silvia Surini (2024)

A new chapter in the pharmaceutical industry has been created by 3D printing, particularly in the manufacturing of solid preparations. This technology can support the modification of medicine in terms of drug dosage. Furthermore, it is achieved b

23-06-2024
Alpha-Amylase Immobilization: Methods and Challenges

Ladan Mafakher (2024)

Alpha-amylase is one of the most widely used enzymes in the starch industry. However, industrial application of soluble alpha-amylase is hampered by changes in pH and temperature (adverse effects on enzyme stability) and activity loss, leading to

23-06-2024
The Novel Pharmacological Approaches to Coumestrol: Focusing on the Psychiatric and Neurological Benefits and the Newly Identified Receptor Interactions

Kiarash Fekri (2024)

For years, the health benefits of coumestrol (CMT) have been investigated by researchers around the world. Anti-oxidative properties of the phytoestrogen which can be extracted from several plant tissues, have already been reported as well as the

23-06-2024
Hansen Solubility Parameters: A Tool for Solvent Selection in Drugs

María Á. Peña (2024)

Hildebrand1 defined the solubility parameter as measures the contribution to the solubility of the cohesive energy density. Then, Hildebrand solubility parameter is calculated from the square root of the cohesive energy density, which is a

23-06-2024
Review and Comparison of Acceptance Criteria for Senna and Its Preparations According to BP (2015 and 2020) and USP-NF (39-34 and 43-38)

Laleh Khodaie (2024)

Background: Quality and quantity assurance of herbs are global concerns. This study aimed to classify and compare the monographs and test procedures of Senna parts and preparations according to two editions of BP and USP-NF. The monographs and sp

23-06-2024
Synthesis and Biological Evaluation of Some Newer 1H-Benzo[b][1,5] diazepin-2(3H)-one Derivatives as Potential Anticonvulsant Agents

Rishipathak Dinesh (2024)

Background: Regardless of the availability of all novel and earlier treatments, seizure control is notoriously complicated. In the hopes of discovering the latest and ultimate therapy, medicinal chemists will keep on to hunt for new antiepileptic

23-06-2024
Influence of Choline-Based Ionic Liquids as Neoteric Green Solvents on Aqueous Solubility of Lamotrigine and Piroxicam Drugs

Hemayat Shekaari (2024)

Background: New compounds called choline-based ionic liquids (ILs) that are environmentally friendly have become more attractive. In this study, some choline-based ILs (choline lactate (ChLa) and choline propionate (ChPro)) have been used to incr

23-06-2024
Modulating Nimodipine Crystallinity for Enhancing Dissolution: Development of Geriatric-Friendly Dosage Form

Howaida E Abdelrahman (2024)

Background: Instant disintegration of oral disintegrating tablets (ODTs) provides a greater chance for buccal absorption, avoiding presystemic metabolism of nimodipine. In addition, ODT can be easily dispersed in suitable liquid before delivery v

23-06-2024
Colchicine for the Prevention of Myocardial Injury Following Elective PCI: A Randomized Clinical Trial

Naser Aslanabadi (2024)

Background: Considering the potential benefits of colchicine in coronary artery diseases, we aimed to carry out the present study to assess the impact of colchicine in the prevention of myocardial injury following elective percutaneous coronary i

23-06-2024
Preventive Effects of Spirulina platensis on Exercise-Induced Muscle Damage, Oxidative Stress and Inflammation in Taekwondo Athletes: A Randomized Cross-Over Trial

Arvin Kashani (2024)

Background: Spirulina is an interesting nutritional supplement that has attracted a lot of attention. The aim of the present study was to examine the effect of spirulina supplementation on oxidative stress, inflammatory factors and plasma markers

23-06-2024
Effect of Melatonin on Paclitaxel-Associated Acute and Chronic Pain: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial

Naeeme Talaee (2024)

Background: Taxane-induced pain is a disabling condition. This trial was conducted to assess the effects of melatonin on preventing paclitaxel-associated acute and chronic pain or decreasing its severity in patients with breast cancer. Methods:

23-06-2024
A Terbium Metal–Organic Framework Platform for Determination of Lamotrigine in Exhaled Breath Condensate

Parisa Eydi (2024)

Background: Lamotrigine is widely used in the management of partial epilepsy, generalized tonic-clonic epilepsy and Lenox-Gastut syndrome and is an add-on therapy in the treatment of complex and simple partial seizures and secondarily generalized

23-06-2024
In Vitro and In Silico Studies on the Anticancer and Antimicrobial Activity of Cu(II), Ni(II) and Co(II) Complexes with Bis (Pyrazolyl) Borate Derivative Ligand

Monireh Ghorbanpour (2024)

Background: The development of the pyrazole-based complexes is greatly enhanced due to the identification of their structure as medicinal application. Keeping in view therapeutic and biological activities of pyrazoles based compounds and the pote

23-06-2024
Synergistic Effect of Quercetin and Cobalt Ferrite-Graphene OxideBased Hyperthermia to Inhibit Expression of Heat Shock Proteins and Induce Apoptosis in Breast Cancer Cells

Fatemeh Mobaraki (2024)

Background: Combinatorial medicine includes promising therapeutic methods for diseases such as cancer, whereby various biochemical and physical agents are simultaneously used to remove tumors. For example, the effectiveness of hyperthermia as a n

23-06-2024
Can Psychobiotics Administration Influence Behavioral Responses and Physiological Stress in Healthy Rats?

Mohamad Morsheedi (2024)

Background: There is a well-documented cross-talk between the gut and brain. Evidence is accumulating to suggest beneficial effects of psychobiotics [prebiotics, probiotics or synbiotics] on psychological distress in disease states. However, thei

23-06-2024
Protective Effects of Mirazid on Gentamicin-induced Nephrotoxicity in Rats through Antioxidant, Anti-inflammatory, JNK1/ iNOS, and Apoptotic Pathways; Novel Mechanistic Insights

Samar A. Antar (2024)

Background: As the use of Gentamicin became more widespread, the drug’s harmful effects, particularly nephrotoxicity, became increasingly well-known. Antibacterial and antiinflammatory properties have long been associated with Mirazid. The goal o

23-06-2024
Andrographolide and Epigallocatechin Gallate (EGCG) Lower the Risk of Addiction Induced by Nicotine and Cigarette Smoke Extract (CSE) in Mice

Samirah Samirah (2024)

Background: Nicotine, a psychoactive compound from the tobacco plant, produces a reward effect that potentially causes addiction. It is postulated that nicotine addiction occurs through increased reactive oxygen species production in nucleus accu

23-06-2024
Pharmaceutical Properties of Hibiscus sabdariffa, Toward an Ideal Treatment for Hypertension

Raha Kamyab (2024)

High blood pressure is the main risk factor for cardiovascular disease and should be controlled primarily by changes in lifestyle, such as regular exercise, a low-salt diet, and weight loss in overweight or obesity. If lifestyle changes are not e

23-06-2024
The Effects of Surgery on Leukocyte Vitamin C Concentrations: A Systematic Review and Meta-Analysis

Nikolaj Travica (2024)

Background: Vitamin C (ascorbic acid) is a micronutrient imperative for many bodily functions, with research revealing its functional support of leukocytes. The purpose of this meta-analysis was to determine the effects of surgery on leukocyte vi

23-06-2024
Natural Deep Eutectic Solvents (NADES)- Progress in Polymer Synthesis and Pharmaceutical Application

Claudio Cecone (2024)

Over the past century, organic synthesis, through the development of novel pharmaceuticals, has led to a revolution in medical care. On the other hand, this practice has created some concerns as it can adversely impact the environment. The so

23-06-2024
Potential Anthelmintic and Antioxidant Activities of Jasminum fruticans L. and Its Phytochemical Analysis

Esra Küpeli Akkol (2024)

Background: Ethnobotanical investigations conducted in Turkey demonstrated that Jasminum fruticans L. extract and fruit juice had been used against parasites in animals. In this study, the possible antihelmintic activity of various J. fruticans e

23-06-2024
Andrographolide-Loaded Ethosomal Gel for Transdermal Application: Formulation and In Vitro Penetration Study

Nooryza Martihandini (2024)

Background: Andrographolide is a phytoconstituent with anti-inflammatory activity, however, the compound’s poor oral bioavailability has hindered its effective formulation for oral administration. This study, therefore, aims to develop an ethos

23-06-2024
The Impacts of Method Selectivity and Binders on the Properties of Carbamazepine Granules and Their Applications: A Case Study

Rahul Tatyarao Shete (2024)

Background: Carbamazepine (CBZ) is a BCS II class drug, having many challenges in solubility, flowability, and compactibility. The study focused on the improvement of solubility, flow behavior, and drug release of carbamazepine. Methods: Low sh

23-06-2024
Development of Chitosan–Tripolyphosphate Nanoparticles as Glycopeptide Antibiotic Reservoirs and Ex Vivo Evaluation for Their Potential to Enhance the Corneal Permeation in Ocular Drug Delivery

Farhad Safari (2024)

Background: The present investigation aimed to prepare Vancomycin-loaded nanoparticles (VAN-NPs) using chitosan (CS) and tripolyphosphate (TPP) besides exploring the effects of changing CS/TPP ratio on the physicochemical properties, corneal perm

23-06-2024
Development of a Nanocluster-Based Platform for Determination of Sofosbuvir

Zahra Karimzadeh (2024)

Background: Sofosbuvir is a potent direct-acting antivirus agent that has been listed as a promising medicine for the treatment of all genotypes of hepatitis C virus. As antiviral drugs could be metabolized to their associated compounds and toxic

23-06-2024
Synthesis of Novel Androstane-N-Cyclohexyl-17-Carboxamides, and Their Effect on the 5?-Reductase Isoform 2, the Androgen Receptor, and Androgen-Dependent Glands

Juan C. Lopez-Lezama (2024)

Background: Benign Prostatic Hyperplasia (BPH), and Prostate Cancer (PCa) are androgendependent diseases. PPCa is associated with excessive signalling of the androgen receptor (AR) due to the binding of 5?-dihydrotestosterone (5?-DHT) and testoster

23-06-2024
Comparing Two Equations for Estimation of Kidney Function (Cockcroft-Gault and Glomerular Filtration Rate Assessment in Liver Disease) for Vancomycin Dosing in Adult Liver Transplant Recipients: A Pilot, Randomized Clinical Trial

Yasaman Saee (2024)

Background: In the setting of impaired liver function, estimation of glomerular filtration rate (GFR) using common creatinine-based equations is inaccurate. Recently, the Glomerular filtration Rate Assessment In Liver disease (GRAIL) model has be

23-06-2024
Preparation and In Vivo Toxicity Study of Allantoin Incorporated Hyaluronic Acid-L-Cysteine Oral Solution: A Future Treatment for Mucositis

Zainab Ahmadian (2024)

Background: Thiolated hyaluronic acid (HA) with interesting properties, such as mucoadhesiveness, enzyme inhibitory, permeation enhancing, and release controlling properties can be applied for drug delivery in various diseases like mucositis. The p

23-06-2024
Expression, Purification and Characterization of Anti-FGF7 Domain Antibody Identified Using Phage Display Technique

Ali Akbar Alizadeh (2024)

Background: Fibroblast growth factors (FGFs) are involved in angiogenesis, wound healing and embryonic development. However, one of the causes of cancer cell growth in fibroblastdependent cancers is FGF7 secreted by fibroblasts. Therefore, antibodi

23-06-2024
EZH2 Knockdown Upregulates Expression of the Genes Involved in T-ALL Cell Differentiation

Sahar Safaei (2024)

Background: EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), as one of the polycyclic group proteins (PcGs), is an epigenetic regulator that plays a crucial role in the pathophysiology of hematologic malignancies through regulati

23-06-2024
Resveratrol Prevents Lipopolysaccharide-Induced Cognitive Impairment in Rats through Regulation of Hippocampal Glua1-Containing AMPA Receptors

Mohammadmehdi Hassanzadeh-Taheri (2024)

Background: Evidence suggests that dysregulation in AMPA-type glutamate receptors (AMPARs) has been associated with the pathogenesis of Alzheimer’s disease (AD), especially during its early phase. Hence, the present study was performed to elucida

23-06-2024
A Review of the Biological Roles of MiR-4800; A Novel Tumor Biomarker with Therapeutic Potential

Monireh Khordadmehr (2024)

MicroRNAs (miRNAs) are known as a group of short noncoding ribonucleic acids (ncRNAs). Mainly, they can manage gene expression at the posttranscriptional level in the essential biological and physiological functions. Significantly, more than 50%

23-06-2024
Antioxidant Activity and Nano Delivery of the Most Frequently Applied Stilbene Derivates: A Brief and Recent Review

Syaiful Choiri (2024)

As of recent, the appearance rate of several degenerative diseases and cancer influenced by oxidative stress continues to increase dramatically. Many compounds with high potential antioxidant activity have been explored and used extensively, i.e.

23-06-2024
Anticancer Effects of Melissa officinalis: A Traditional Medicine

Parviz Faraji (2024)

Melissa officinalis (M. officinalis) is an herbal-based plant from the family of Lamiaceae and native to Europe and the Mediterranean region, widely used to cure various cancers. Phytochemical investigations proved different compounds such as pol

23-06-2024
Active Targeting Gold Nanoparticle for Chemotherapy Drug Delivery: A Review

Azhoma Gumala (2024)

Active targeting strategy in chemotherapy drug delivery aims to improve the therapeutic outcomes and minimize the side effects of chemotherapeutics. This review discusses utilizing ligands attached to gold nanoparticles (AuNPs) along with several

23-06-2024
Professor Jalil Afshar; The Founding Editor of Pharmaceutical Sciences

Abolghasem Jouyban (2024)

Prof. Jalil Afshar (Figure 1) obtained his PharmD degree from University of Tabriz in 1965, then joined the Faculty of Pharmacy at University of Tabriz in 1968 as a lecturer. In 1970, Prof. Afshar passed a short course at the University of Bo

23-06-2024
Metronidazole Induced Anaphylactic Shock: A Case Report

Mahsa Panahi Shokouh (2024)

Anaphylactic shock is a type-1 hypersensitivity reaction occurring after exposure to foods, drugs, or chemicals and can be accompanied by unfortunate consequences such as death. Among various drugs, antibiotics, especially cephalosporins and

23-06-2024
Biological Activity Survey of Pereskia aculeata Mill. and Pereskia grandifolia Haw. (Cactaceae)

Adriana Muniz Massocatto (2024)

Background: Pereskia aculeata and P. grandifolia are non-traditional Brazilian vegetables with high nutritional value used in traditional medicine. The antioxidant, anticholinesterase, molluscicidal, cytotoxic, and antiproliferative properties of

23-06-2024
Microencapsulation of Enriched Extracts of Two Satureja Species by Spray Drying, Evaluation of the Controlled Release Mechanism and Cytotoxicity

Faezeh Fathi (2024)

Background: Phenolic compounds are one of the main groups of secondary metabolites responsible for multiple biological and pharmacological properties that play a vital role in improving human health quality. Encapsulation by spray dryer creates p

23-06-2024
Solubility, Correlation, Dissolution Thermodynamics and Preferential Solvation of Meloxicam in Aqueous Mixtures of 2-Propanol

Darío A. Tinjacá (2024)

Background: Meloxicam is an analgesic drug widely used in current therapeutics. Because the very low equilibrium solubility of meloxicam in neat water, this property has been studied in {2-propanol + water} mixtures from (293.15 to 313.15) K to e

23-06-2024
Effects of Transcutol P and Precirol ATO-5 on Percutaneous Absorption of Flutamide from Emulgels

Parandis Khalilollah (2024)

Background: Flutamide is a non-steroidal anti-androgenic agent which is not only used in treating prostate cancer but also can be effective in some disorders such as androgenic alopecia and male pattern baldness. Several serious side effects for

23-06-2024
Effects of Pentoxifylline on Inflammatory Factors and Quality of Life in Maintenance Hemodialysis Patients

Lachin Rezadoost (2024)

Background: Increased inflammatory cytokines including C-reactive protein (CRP) and tumor necrosis factor-alpha (TNF-?) are a common finding in patients with particularly those with end-stage renal disease (ESRD), which can lead to several compli

23-06-2024
Fast-Dissolving Sublingual Nanofibers of Ondansetron Hydrochloride: Formulation, Physicochemical Characterization, and Clinical Evaluation on Post-cataract Surgery Patients

Samira Kamranpour (2024)

Background: Ondansetron hydrochloride (OND) is an antiemetic agent belongs to the 5-HT3 receptor antagonist class administrated widely in relieving nausea and vomiting which is the most common complication occurred after surgery. This study aimed

23-06-2024
Calcitriol versus Cholecalciferol on Biochemical Markers of Metabolic Bone Disease in Very Low Birth Weight Infants: A Randomized Clinical Trial

Mohammad Bagher Hosseini (2024)

Background:About 55% of extremely-low-birth-weight (birth weight < 1000 g) and 23% of verylow-birth-weight infants (birth weight < 1500 g) suffer from metabolic bone disease (MBD). There are limited data on the use of calcitriol (1, 25-dihydr

23-06-2024
Evaluation of the Potential Role of Silver Nanoparticles Loaded with Berberine in Improving Anti-Tumor Efficiency

Mohamed S. Othman (2024)

Background: Cancer is a progressive disease, its incidence and death rates are rapidly increasing globally. Numerous adverse effects are associated with the available interventions. Hence, the current study was undertaken to explore the anticance

23-06-2024
Concanavalin-A Shows Synergistic Cytotoxicity with Tamoxifen via Inducing Apoptosis in Estrogen Receptor-Positive Breast Cancer: In Vitro and Molecular Docking Studies

Mohamed F. Elshal (2024)

Background: Tamoxifen (TAM) is the main treatment of estrogen receptor (ER)-positive breast cancer, however; its adverse effects and development of resistance hinder its use. Concanavalin A (Con A) is a mannose/glucose-binding lectin that has bee

23-06-2024
Trado-Medical Uses, Chemical Constituents and Biological Activities of Newbouldia laevis (Bignoniaceae): A Review

Innocent U. Okagu (2024)

Newbouldia laevis (P. Beauv.) Seem. (Family, Bignoniaceae), commonly known as tree of life, is a purple-flowering plant that is widely distributed in many parts of Africa. Different parts of the plant, including the leaves, flower, stems and root

23-06-2024
Sodium Bicarbonate versus Statins to Prevent Contrast-induced Acute Kidney Injury: A Comprehensive Review

Sanam Dolati (2024)

Iodinated contrast agents are commonly used in diagnostic radiography techniques along with therapeutic interventions. Contrast-Induced Acute Kidney Injury (CI-AKI) is a significant problem of all angiographic procedures, triggered by the use of

23-06-2024
Nicolau Syndrome: A Review of Case Studies

Paria Mojarrad (2024)

Nicolau syndrome, although it is quite rare, often occurs following intramuscular injections of different medications, especially diclofenac and penicillins. Accordingly, its symptoms usually begin with severe pain during injection, leading to ul

23-06-2024
Development of Imaging and Liquid Biomarker Analysis for Breast Cancer Screening: A Review

Atmedi Surendra (2024)

Background: Breast cancer screening tests could reduce the mortality rates for breast cancer patients. Screening and detection are the keystone of cancer prevention and may significantly minimize the death rates in breast cancer patients for long

23-06-2024
Mechanistic Insight on Ras Inhibition Strategies in Cancer Therapy

Jeiran Pashapour Anousheh (2024)

Ras proteins are considered as one of the most critical cancer initiators. Mutations of this protein family lead to the continuous activation of the proliferation pathways. Therefore, many efforts have been taken to design the anti-mutant Ras dru

23-06-2024
Analysis of Retracted Articles in Pharmacology and Pharmacy

Sara Jalalzadeh (2024)

Retraction is one of the most challenging issues raised when dealing with unethical cases. In accordance with the retraction guidelines published by the Committee on Publication Ethics (COPE), the main purpose of retraction is to correct lite

23-06-2024
Impact of Storage Conditions on a New Child-Friendly Dispersible Tablet for Treating Tuberculosis in Pediatrics

Javier Suárez-González (2024)

Background: In 2020 the composition and procedure to elaborate a new formulation containing Isoniazid, Pyrazinamide and Rifampicin to treat tuberculosis in pediatric patients was published. The temperature and relative humidity in Tuberculosis-en

23-06-2024
The Association of Kidney’s GFR and Serum Creatinine Levels with Renal Scarring through 99mTc-Glucoheptonate Radiopharmaceutical Scan in Patients with Urinary Tract Infection

Ashraf Fakhari (2024)

Background: UTI (urinary tract infection) is a leading case of renal scarring. Most of nephrons are found in kidney cortex, so it is important for early diagnosis of scarring. In this study, we investigated if scarring affects GFR (glomerular fil

23-06-2024
Anti-proliferative and Apoptotic Effect of Tetrahydrobenzo[h]quinoline on MCF-7 Human Breast Cancer Cell

Maryam Ghaffari (2024)

Background:Quinoline and its derivatives display various biological activities based on versatility in designing a new drug class for medicinal applications. Hence, synthesizing innovative and varied derivatives of quinoline has gained considerab

23-06-2024
Enhancement of Cisplatin Sensitivity by Microwave Radiation in Ovarian Cancer Cells

Mansour Tayebi-khorami (2024)

Background: Nowadays, ovarian cancer is the most lethal gynecological cancer worldwide. Tumor debulking surgery followed by Cisplatin-based chemotherapy is the first line of ovarian cancer therapy. However, many patients experience a relapse of t

23-06-2024
Structure Based Virtual Docking and Molecular Dynamics Guided Identification of Potential Phytoconstituents from Traditionally Used Female Antifertility Plant

Keerthi Priya (2024)

Background: Oral contraceptives are very widely used agents to check unwanted pregnancies. They contain synthetic analogues of estrogen and progesterone hormones. Estrogen is an important hormone that plays a significant role in menstrual cycle, o

23-06-2024
In Vivo Evaluation of Wound Healing Properties of Platanus orientalis L.

Somayeh Niknam (2024)

Background:According to the Iranian Traditional Medicine (ITM) references, Platanus orientalis L. possesses wound healing properties. Herein, we developed different topical formulations based on the ethanolic extract of P. orientalis leaves and ev

23-06-2024
Coumestrol Alleviates Oxidative Stress, Apoptosis and Cognitive Impairments Through Hippocampal Estrogen Receptor-Beta in Male Mouse Model of Chronic Restraint Stress

Kiarash Fekri (2024)

Background: Coumestrol is well-known as a natural estrogen receptor-beta modulator. Since the role of estrogen receptors in controlling stressful situations has already been reported and their cognitive functions in hippocampus seem to be indepen

23-06-2024
Selegiline Alleviates the Depressive-Like Behaviors of Methamphetamine Withdrawal Syndrome Through Modulating Mitochondrial Function and Energy Hemostasis

Mir-Jamal Hosseini (2024)

Background: Methamphetamine (METH) is considered the second most commonly abused drug in the world. There is limited or no evidence concerning the effective treatment of METH withdrawal symptoms, such as depression and anxiety. Mode of action of

23-06-2024
Broad-Spectrum Cannabis Oil Alleviates Behavioral Symptoms Associated with Stress-Related Anxiety and Depression in Mice

Pollyana Mendonça de Assis (2024)

Background: Posttraumatic stress disorder (PTSD) is a psychiatric condition that manifests through a broad range of symptoms and shares several phenotypes with anxiety and depression. Refractory PTSD affects 10–30% of the patients and highlight

23-06-2024
A Mini Review of Neuropharmacological Effects of Rosa damascena Herrm

Farimah Beheshti (2024)

Background: Rosa damascena Herrm (R. damascena) is a species of the Rosaceae family. The R. damascena has been shown to improve depression, anxiety and grief. It also suppresses allergic reactions and migraine headache. In addition, amelioration

23-06-2024
Historical Course of Neuropsychiatric Effects of Lemon Balm (Melissa officinalis L.) as a Medicinal Herb

Javid Ghazizadeh (2024)

Affective disorders have become prevalent and costly worldwide chronic conditions. Lemon Balm (Melissa officinalis L.) is a medicinal plant with beneficial effects on neuropsychiatric disorders. Its potential to specifically treat conditions such

23-06-2024
Solubilization Methods for Paclitaxel and Docetaxel: An Overview

Fariba Pourkarim (2024)

Cancer is still a serious disease with high incidence over the past decades. Many anticancer drugs are discovered and used to treat cancer, among them, taxanes such as paclitaxel and docetaxel have high lipophilicity and low aqueous solubility wh

23-06-2024
Encapsulating Vitamin D: A Feasible and Promising Approach to Combat Its Deficiency

Mina Esmaeili (2024)

Vitamin D (VD) deficiency is a significant issue affecting a large population around the world. As its natural sources are limited, people must constantly fortify their VD. Encapsulating VD increases its bioavailability and stability during proce

23-06-2024
Lipid Polymeric Hybrid Nanoparticles: Formulation Techniques and Effects on Glioblastoma

Yudhishtir Singh Baghel (2024)

In the pharmaceutical industry, liposomes and polymeric nanoparticles are the two most commonly studied delivery vehicles. A new technique uses lipid-polymeric hybrid nanoparticles (LPHNPs) with a polymeric core, and a shell made up of lipid-lipi

23-06-2024
23-06-2024
Risk Factors of Supply Chain in Biopharmaceutical Companies in Iran

Hadi Abbasian (2024)

Background: Supply chain risk management can help companies detect potential hazards, mitigate potential risks, and thereby increase supply chain efficiency. The biopharmaceutical industry in Iran has a generic-based pharmerging market. Therefore

23-06-2024
The Impact of Clinical Pharmacist Interventions on Medication Errors Management in the Postoperative Cardiac Intensive Care Unit

Naser Safaie (2024)

Background: Medication errors (MEs) frequently occur in intensive care unit (ICU) admitted patients. The present study aimed to evaluate the frequency and types of MEs in an open heart surgery heart ICU and clinical pharmacists’ role in the man

23-06-2024
Efavirenz Loaded Nanostructured Lipid Carriers for Efficient and Prolonged Viral Inhibition in HIV-Infected Macrophages

Ketan Mahajan (2024)

Background: The clinical outcome of anti-HIV therapy is poor due to the inherent fallouts of anti-HIV therapy. It is further worsened due to the presence of viral reservoirs in immune cells like the macrophages. An ideal anti-HIV therapy must rea

23-06-2024
In Vitro Studies of Prednisolone Loaded PLGA Nanoparticles-Surface Functionalized With Folic Acid on Glioma and Macrophage Cell Lines

Sriprasad Acharya (2024)

Background: Glucocorticoids are employed for their anti-inflammatory effects in treating glioma, whose cells are known to overexpress the folate receptors. Some glucocorticoids have shown inhibitory effects, but the efficacy of prednisolone when

23-06-2024
Evaluation of Pharmaceutical Compatibility between Acarbose and Common Excipients Used in the Development of Controlled Release Formulations

Aiesheh Gholizadeh-Hashjin (2024)

Background: Excipients are used in the formulation of pharmaceutical dosage forms, but may interact with active pharmaceutical ingredients (APIs). Some of these interactions could alter the physicochemical properties of the APIs which can affect

23-06-2024
Increased Expression of DNA Methyltransferase 1 and 3B Correlates with Tumor Grade in Laryngeal Squamous Cell Carcinoma

Nooshin Mohammadzadeh (2024)

Background: DNA methyltransferase (DNMT) enzymes, encoded by DNMT1, DNMT3A and DNMT3B genes, play a major role in the development of cancers through aberrant promoter methylation. Due to little information about the biological and clinical signif

23-06-2024
Expression Profile of LncRNAs in Childhood Acute Lymphoblastic Leukemia: A Pilot Study

Zohreh Mousavi (2024)

Background: Childhood acute lymphoblastic leukemia (ALL) explains 26% of pediatric malignancies and is one of the leading causes of disease-related deaths in children. A novel molecular class of non-coding genes, long non-coding RNAs (lncRNAs) ha

23-06-2024
Investigating the Effects of Salvia chorassanica Bunge and Shoot Extracts on Gastric Cancer Cells: Evidence of Different Behavior on Various Tumor Grades

Fatemeh Karami (2024)

Background: Different Salvia species have demonstrated anti-proliferative effects on various cancer cells. Owing to the poor literature on the anti-proliferative effects of Salvia species on gastric cancer cells, present study was conducted to de

23-06-2024
Investigation of Experimental and In Silico Physicochemical Properties of Thiazole-Pyridinium Anti-Acetylcholinesterase Derivatives with Potential Anti-Alzheimer’s Activity

Golaleh Ghotbi (2024)

Background: Physicochemical properties play important role in fundamental issues like absorption and distribution of pharmaceuticals to the target tissue. This is particularly important for drugs acting in central nervous system (CNS). In

23-06-2024
Synthesis, Anti-Inflammatory Activity and Molecular Docking Studies of 1,4,5,6-Tetrahydropyrimidine-2-Carboxamides

Volodymyr Ya. Horishny (2024)

Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs in the world. The widespread use of NSAIDs is associated with a number of serious side effects and complications observed for both selective and non-

23-06-2024
Synthesis, Molecular Docking and Anticancer Activity of Novel 1,3- Thiazolidin-4-Ones

Ramesh Sawant (2024)

Background: Cancer is a major cause of death all over the globe. Controlling cell division by inhibition of mitosis is the most successful clinical strategy for cancer treatment. The development of novel anticancer agents is the most important ar

23-06-2024
Effects of Sodium Selenite and Vitamin E on the Development of Morphine Dependency in Mice

Bohloul Habibi-Asl (2024)

Background: Antioxidant drugs may be useful in preventing morphine-induced dependency by suppressing oxidative stress. Vitamin E which has many essential roles in the body is a powerful antioxidant. On the other hand, selenium is an essential tra

23-06-2024
Anti-Inflammatory and Analgesic Activities of 7-Chloro-4-(Piperazin1-yl) Quinoline Derivative Mediated by Suppression of Inflammatory Mediators Expression in Both RAW 264.7 and Mouse Models

Mona Elsayed Aboutabl (2024)

Background: 4-Aminoquinoline derivatives possess various potential biological properties. The introduction of additional piperazine heterocyclic pharmacophoric moiety tends to have profound impact in increasing the activity. The present work was

23-06-2024
The Role of HSA21 Encoded Mirna in Down Syndrome Pathophysiology: Opportunities in miRNA-Targeted Pharmacotherapy and Diagnosis of the Down Syndrome

Shabnam Mahernia (2024)

Trisomy 21 is the most prevalent aneuploidy disorder among live-born children worldwide. It results from the presence of an extra copy of chromosome 21 which leads to a wide spectrum of pathophysiological abnormalities and intellectual disabiliti

23-06-2024
Natural Products as Inhibitors of COVID-19 Main Protease – A Virtual Screening by Molecular Docking

Marzieh Omrani (2024)

Background: The novel coronavirus (2019-nCoV) causes a severe respiratory illness unknown to a human before. Its alarmingly quick transmission to many countries across the world has resulted in a global health emergency. Therefore, an imminent ne

23-06-2024
Qualitative and Quantitative Analysis of Anti-viral Compounds against SARS-CoV-2 Protease Enzyme by Molecular Dynamics Simulation and MM/PBSA Method`

Saghi Sepehri (2024)

Background: A significant worry for global public health is the international spread of the coronavirus disease-19 triggered through the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Herein, an attempt was performed to qualita

23-06-2024
Molecular Docking and Dynamics Simulations Reveal the Potential of Anti-HCV Drugs to Inhibit COVID-19 Main Protease

Ahmed A. Al-Karmalawy (2024)

Background: Drug repurposing is the fastest effective method to provide treatment for coronavirus disease (COVID-19). Drugs that targeting a closely related virus with similar genetic material such as hepatitis C virus (HCV) and more specifically

23-06-2024
The Integration of Pharmacophore-Based 3D-QSAR Modeling and Virtual Screening in Identification of Natural Product Inhibitors against SARS-CoV-2

Samira Norouzi (2024)

Background: The current outbreak of Coronavirus Disease 2019 (SARS-CoV-2) led to public health emergencies all over the world and made it a global concern. Also, the lack of an effective treatment to combat this virus is another concern that has

23-06-2024
Potential Sedative and Therapeutic Value of Dexmedetomidine in Critical COVID-19 Patients

Saeid Safari (2024)

The coronavirus 2019 disease (COVID-19) is an ongoing outbreak of respiratory disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The virus can invade various tissues and organs, causing multiple organ dysfunctions. C

23-06-2024
A New Possible Indication of Direct-acting Anti-hepatitis C Drugs in the Therapeutic Management of COVID-19: A Narrative Literature Review

Alireza Mashhadi Hemmatabadi (2024)

COVID-19 is the latest human crisis to hit most parts of the world since its emergence in China. High prevalence, rapid transmission, and high mortality rates make it necessary to find an effective therapy immediately. Repurposing the available d

23-06-2024
Acyclovir as a Potential Add-on Therapy in COVID-19 Treatment Regimens

Fatemeh Heidary (2024)

Background: There are successful reports of the concomitant management of herpes infection and coronavirus disease 2019 (COVID-19), using both acyclovir (ACV) and COVID-19 treatment regimens. Furthermore, ACV has been proposed to effectively trea

23-06-2024
The Clinical Characteristics and Treatment Approaches of COVID-19: A Concise Review

Sajjad Eslamkhah (2024)

A series of cases of pneumonia occurred in China in late 2019. For this type of coronavirus, the World Health Organization (WHO) formally identified the condition as a coronavirus disease 2019 (COVID-19). They announced that this disease is the r

23-06-2024
Potential Roles of Vitamins in the Management of COVID-19: A Comprehensive Review

Homa Rezaei (2024)

The coronavirus disease 2019 (COVID-19) outbreak has caused a public health crisis worldwide. However, data regarding the protective factors of the disease is limited. Consequently, preventive health measures that can decrease the risk of infecti

23-06-2024
Anti-Rheumatic Drugs as Potential Anti-inflammatory, Immunomodulatory Agents against COVID-19: A Systematic Review

Reza Sinaei (2024)

Background: The effective responses of both innate and adaptive immunity are crucial in combating novel coronavirus-2 infection. An excessive response may lead to cytokine storm, which is a challenging problem in therapeutic strategies. Methods

23-06-2024
The Impact of Vitamin D Supplementation on Mortality Rate and Clinical Outcomes of COVID-19 Patients: A Systematic Review and Meta-Analysis

Leila Nikniaz (2024)

Background: Several studies have suggested the positive impact of vitamin D on patients infected with SARS-CoV-2. This systematic review aims to evaluate the effects of vitamin D supplementation on clinical outcomes and mortality rate of COVID-19

23-06-2024
Hydrophilic Sugars for Enhancing Dissolution Rate of Cilostazol: Effect of Wet Co-Processing

Alaa Y. Bazeed (2024)

Background: Cilostazol is an anti-platelets drug with considerable antithrombotic effects in vivo. Therefore, it is widely used by elderly patients. However, it suffers from poor bioavailability due to its low aqueous solubility. The objective of

23-06-2024
23-06-2024
Essential Oil Analysis and Isolation of Coumarins and Flavonol Glycosides of Ferulago angulata (Schltdl.) Boiss. Fruits

Hedieh Farokhi-Firoozi (2024)

Background: Ferulago angulata (Schltdl.) Boiss. is a herbaceous perennial plant distributed in Iran, Turkey and Iraq. The aromatic aerial parts of this plant are commonly used as antiseptic, sedative, wound healing, analgesic and food additive.

23-06-2024
Protective Effect of Merbau (Intsia bijuga) Extract on Hydrogen Peroxide-Treated HaCaT Human Keratinocytes and Its Formulation as Antioxidant Cream

Leonny Yulita Hartiadi (2024)

Background: The excessive generation of ROS in the skin results in oxidative stress that can contribute to premature skin aging, inflammation, and skin carcinogenesis. To prevent these detrimental effects, the development of herbal medicine with

23-06-2024
Polycyclic Aromatic Hydrocarbons Degradation by Aquatic Bacteria Isolated from Khazar Sea, the World’s Largest Lake

Vida Ebrahimi (2024)

Background: Aquatic microorganisms have an important role in the bioremediation of environmental pollutants. Polycyclic Aromatic Hydrocarbons (PAHs) are described as dangerous pollutants that can bind covalently to the nucleic acids, causing muta

23-06-2024
Polyphenol Enriched Extract of Pomegranate Peel; A Novel Precursor for the Biosynthesis of Zinc Oxide Nanoparticles and Application in Sunscreens

Maryam Kokabi (2024)

Background: Green synthesized nanoparticles (NPs) from agricultural wastes is an area of great interest due to it is eco-friendly and profitable. Zinc oxide is an inorganic UV-filter commonly used as UV-blocker in a different industry. Methods:

23-06-2024
Solubility Enhancement of Betamethasone, Meloxicam and Piroxicam by Use of Choline-Based Deep Eutectic Solvents

Salva Golgoun (2024)

Background: The low aqueous solubility of three important drugs (betamethasone (BETA), meloxicam (MEL) and piroxicam (PIR)) have been increased by use of deep eutectic solvents (DESs) based choline chloride/urea (ChCl/U), choline chloride/ethylen

23-06-2024
Development of Sodium Sulfate Induced Water Based Dispersive Liquid–Liquid Microextraction for the Extraction of Four Tricyclic Antidepressants in Urine Samples Prior to Their Determination by Gas Chromatography–Mass Spectrometry

Ali Mohebbi (2024)

Background: Because of the narrow therapeutic range of tricyclic antidepressant drugs, their determination in biological samples is of great importance. In this work, a fast and environment friendly sample pretreatment method based on a dispersiv

23-06-2024
An Epithelial Sodium Channel (ENaC)-Specific Aptamer Determined through Structure-Based Virtual Screening for the Development of Hypertension Early Detection System

Dina Ratna Komala (2024)

Background: Epithelial sodium channel (ENaC) is a transmembrane protein involved in maintaining sodium levels in blood plasma. It is also a potential biomarker for the early detection of hypertension since the amount of ENaC is related to the fam

23-06-2024
Association between ECG Alterations and Outcomes of Patients with Acute Organophosphate Poisoning

Kavous Shahsavari Nia (2024)

Background: Organophosphate (OP) poisoning leads to atrioventricular node blockade, alterations in ST segment, prolongation of QT interval, alterations in P wave, lethal arrhythmias, and cardiac arrest through the inhibition of acetylcholinestera

23-06-2024
Protective Effects of Osthole against Free Radical-Induced Hemolysis of Erythrocytes

Soroush Rashidpour (2024)

Background: Osthole, one of the most active components of Cnidium monnieri, has different pharmacological and biological effects such as boosting the immune system, reducing rheumatoid pain, hepatoprotective, and inhibitory effect on osteoporosis

23-06-2024
Immunomodulatory Effects of Cyperus rotundus Extract on 7,12-Dimethylbenz[a]anthracene (DMBA) Exposed BALB/c Mice

Abu Hanifah Ramadhani (2024)

Background: The carcinogenic substance 7,12-Dimethylbenz[a]anthracene (DMBA) was commonly used to induce tumor formation in rodents. The development of tumor may trigger higher expression of pro-inflammatory cytokines, which in turn supports tumo

23-06-2024
Carnosine Mitigates Biomarkers of Oxidative Stress, Improves Mitochondrial Function, and Alleviates Histopathological Alterations in the Renal Tissue of Cholestatic Rats

Omid Farshad (2024)

Background: Cholestatic liver disease primarily affects hepatic tissue. Cholestasis could also influence the function of other organs rather than the liver. Cholestasis-induced kidney injury is a severe clinical complication known as “cholemic

23-06-2024
Boswellic Acids as Promising Leads in Drug Development against Alzheimer’s Disease

Hossein Haghaei (2024)

Biological activity of Boswellia extract (BE) has been attributed to its main active ingredients; i.e. Boswellic acids (BAs). BE/BAs possess a promising therapeutic potential in neurodegenerative disorders; including Alzheimer’s disease (AD). T

23-06-2024
Cucurbitacins: A Focus on Cucurbitacin E As A Natural Product and Their Biological Activities

Moazzameh Ramezani (2024)

For the last years, different types of cucurbitacins have been extracted from various species of Cucurbitaceae family. For this review, all related papers were accumulated by searching electronic databases in the English language, including PubMe

23-06-2024
A Simple Colorimetric Method for Determination of Ethanol in Exhaled Breath Condensate

Fariba Pourkarim (2024)

Background: Ethanol is considered as a toxic compound when used in excess amounts. The toxic concentration for ethanol was reported to be 1000 – 2000 ?g.mL-1 in plasma and serum samples. The aim of the current study was to develop a rapid and c

23-06-2024
Evaluating the In Vitro Activity of Depsidones from Usnea subfloridana Stirton as Key Enzymes Involved in Inflammation and Gout

Thanh-Trung Nguyen (2024)

Background: Traditionally, Usnea genus has significant uses in the treatment of swelling and tumors in Africa and Asia. The aim of the present study was to investigate the chemical constituents present in the acetone extract (AE) of Usnea subflor

23-06-2024
Muscodor sp. IBRL OS-94, A Promising Endophytic Fungus of Ocimum sanctum with Antimicrobial Activity

Mohd Taufiq Mat Jalil (2024)

Background: An endophytic fungus, Muscodor sp. IBRL OS-94 isolated from the leaf of Ocimum sanctum was believed to possess significant antimicrobial activity and several assays were carried out to evaluate its pharmaceutical potential. Methods:

23-06-2024
Anti-Cancer Effects of Probiotic Lactobacillus acidophilus for Colorectal Cancer Cell Line Caco-2 through Apoptosis Induction

Alireza Isazadeh (2024)

Background: Colorectal cancer is one of the most common cancers worldwide. Probiotics are useful and non-pathogenic microorganisms in the gastrointestinal tract, which can show anticancer activity through the induction of apoptosis. This study ai

23-06-2024
Prophylactic Role of Lactobacillus paracasei Exopolysaccharides on Colon Cancer Cells through Apoptosis Not Ferroptosis

Yalda Rahbar Saadat (2024)

Background: Nowadays despite conventional methods in colon cancer treatment, targeting vital molecular pathways and induction of various forms of cell death by safe probiotic components like exopolysaccharides (EPSs) are of great importance and a

23-06-2024
Green Synthesis of Gold Nanoparticles Mediated by Garcinia Fruits and Their Biological Applications

Azazahemad A. Kureshi (2024)

Background: Green synthesis of gold nanoparticles (AuNPs) using medicinal plant extract is an emerging area of research due to their applicability in nanomedicines. Methods: In this study, aqueous extracts prepared from fruit-pericarps of two Garc

23-06-2024
Effect of Processing/Formulation Parameters on Particle Size of Nanoemulsions Containing Ibuprofen - An Artificial Neural Networks Study

Ali Hanafi (2024)

Background: Nanoemulsions are colloidal transparent systems for the delivery of hydrophobic drugs. This study aimed to determine the effect of parameters affecting particle size of a nanoemulsion containing ibuprofen using artificial neural netwo

23-06-2024
Design of Experiment Centered Multivariate Optimization Strategy for RP-HPLC Method to Quantitate Retapamulin in Topical Cream and Microemulsion

Rashmin Patel (2024)

Background: Retapamulin is the first pleuromutilin antibacterial approved for the treatment of impetigo. The objective of the current research was to utilize the design of experiments approach for development and optimization of robust RP-HPLC me

23-06-2024
6,7-Disubstituted-4-anilinoquinazoline: Design, Synthesis and Anticancer Activity as a Novel Series of Potent Anticancer Agents

Fatemeh Azmian Moghadam (2024)

Background: Epidermal Growth Factor Receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR) are responsible for several pathological conditions such as the development of different kinds of tumors. The combined inhibition of both

23-06-2024
Evaluation of the Association between Trough and Area Under the Curve to Minimum Inhibitory Concentration Ratio (AUC24/ MIC) of Vancomycin in Infected Patients with Methicillin Resistant Staphylococcus aureus (MRSA)

Ayda Esmaeili (2024)

Background: The recent studies emphasized on the correlation of vancomycin antibacterial effect with pharmacokinetics properties such as the area under the curve/minimum inhibitory concentration (AUC24/MIC) ?400 and serum trough level 15-20 mg /L

23-06-2024
Investigation of Protective Effects of Quercetin on Oxidative Stress Induced by Vinblastine in Bone Marrow of Rats

Hamed Aramjoo (2024)

Background: Chemotherapy drugs such as vinblastine cause oxidative stress in the bone marrow resulting changes in blood cell production and anemia. In this study, the antioxidant and therapeutic potential of quercetin was evaluated. Methods: Tw

23-06-2024
Neurodevelopmental Toxic Effects of Food Additives Used in Energy Drinks on Developing Rats

Revathi Boyina (2024)

Background: Food additives are widely used in energy drinks and when taken above acceptable daily intake leads to various neurodevelopmental toxic effects. The present study aimed to evaluate the neurodevelopmental toxic effects in rat pups after

23-06-2024
Phytochemical Screening and Evaluation of the Antiarthritic Potential of Ammoides pusilla Aqueous Extract on Freund's Adjuvant-Induced Rheumatoid Arthritis

Hamza Belkhodja (2024)

Background: Ammoides pusilla plant is a species of therapeutic interest which used in traditional medicines. This work aims to valorize this plant by the characterization of their bioactive components and the evaluation of the in vivo anti-inflam

23-06-2024
The Effects of Hydroalcoholic Extract of Arum orientale on CLP-Induced Sepsis in Rats

Setare Soleimanipour (2024)

Background: Sepsis is a lethal clinical syndrome that results from dysregulated systemic inflammatory response of the body due to the invasion of pathogens, especially bacteria. Despite advances in medical care and therapy, sepsis is still one of

23-06-2024
Exhaled Breath Condensate: A Non-Invasive Source for Tracking of Genetic and Epigenetic Alterations in Lung Diseases

Somayeh Kazeminasab (2024)

Lung diseases have been recognized as an extensive cause of morbidity and mortality in the worldwide. The high degree of clinical heterogeneity and nonspecific initial symptoms of lung diseases contribute to a delayed diagnosis. So, the molecular

23-06-2024
Mechanochemical Synthesis of A Novel Eutectic of the Antimicrobial Nitazoxanide with Improved Dissolution Performance

Octavio E. Fandiño (2024)

Background: Nitazoxanide (NTZ) is a broad spectrum antimicrobial agent with poor aqueous solubility and low bioavailability. Thus, the generation of new solid forms of NTZ is relevant to improve its unfavorable properties. The present study deals

23-06-2024
Determination of Chlorzoxazone Crystal Growth Kinetics and Size Distribution under Controlled Supersaturation at 293.15 K

G. Satish (2024)

Background: Chlorzoxazone (CHZ) is a water-insoluble drug having bioavailability problems. The absorption rate of such drugs can be improved by reducing their particle size. In this work, the crystal growth kinetics of CHZ–ethanol for different

23-06-2024
A Comparison on Effects of High Dose Rosuvastatin versus High Dose Atorvastatin on Lipid Profile and CRP Level in Patients Undergoing Percutaneous Coronary Intervention: A Randomized Study

Mahboubeh Darban (2024)

Background: Statins are the most common drugs used for reducing low-density lipids (LDL). In addition to their lipid-lowering effects, they have well-documented anti-inflammatory actions. The goal of this study was to compare the effects of high

23-06-2024
The Effects of Allopurinol on Levels of Cardiac Troponin Following Non-ST Elevation Myocardial Infarction: A Pilot Randomized Clinical Tri

Sajad Khiali (2024)

Background: Given the potential anti-ischemic effects of allopurinol, we aimed to assess whether allopurinol administration may reduce myocardial injury following non-ST elevation myocardial infarction (NSTEMI). Methods: A randomized clinical t

23-06-2024
Evaluation of Methylation at Promoter Regions of Long Non-coding RNAs in Patients with Acute Lymphoblastic Leukemia

Zohreh Mousavi (2024)

Background: Acute lymphoblastic leukemia (ALL) is a fetal hematologic disorder that is mostly observed in children. Both B and T lymphocytes have been reported to play a role in ALL etiology. Long non-coding RNAs (lncRNAs) are large regulatory mo

23-06-2024
Pinus roxburghii Constituents Augment Human Lymphocytes Mediated Cytotoxicity Towards Cancer Cells

Henok Gullilat (2024)

Background: Pinus roxburghii has been used in the Himalayan region as folkloric remedy while nothing is yet known about its immunomodulatory potential. Methods: The crude extracts of green and fallen pine needles were subjected to sequential fra

23-06-2024
The Combination of Berberine and Methotrexate Enhances Anti-Cancer Effects in Hela Cancer Cell Line: A Morphological Study

Hossein Majidzadeh (2024)

Background: Co-administration of two or several either chemotherapeutic agents or conventional drugs as a combination treatment is the most effective method to increase therapeutic efficiency. Additive or synergistic influence are two mechanisms

23-06-2024
The Combination of Berberine and Methotrexate Enhances Anti-Cancer Effects in Hela Cancer Cell Line: A Morphological Study

Hossein Majidzadeh (2024)

Background: Co-administration of two or several either chemotherapeutic agents or conventional drugs as a combination treatment is the most effective method to increase therapeutic efficiency. Additive or synergistic influence are two mechanisms

23-06-2024
Green Curmin Reduces Pro-inflammatory Cytokines and Fibroblast - Associated Colon Cancer Migration

Nasapon Povichit (2024)

Background: Green Curmin is a soluble curcumin extract product made in Thailand that has been reported to reduce gastric inflammation. Inflammatory cytokines including IL-1?, IL-6, and TNF-? play a crucial role in cancer cell migration, which is

23-06-2024
The Antioxidant Effects of Calligonum Extract on Oxidative Stress in Spermatogonial Stem Cells Culture

Shirin Barati (2024)

Background: Spermatogenesis is a programmed route for germ cell proliferation and differentiation that can produce abundant numbers of spermatozoa. The antioxidants play a vital role in decreasing oxidative stress production in cells; therefore,

23-06-2024
Tadalafil Modulates Intracerebroventricular Streptozotocin-Induced Cognition and Memory Impairment in the Young and Middle-Aged Rats

Siamak Shahidi (2024)

Background: Learning and memory may decline due to Alzheimer’s disease (AD) in older adults. A reduction in cyclic guanosine monophosphate concentration and an increase in phosphodiesterase activity have been reported in the process of aging. A

23-06-2024
The Potential Use of Aptamers in The Process of Drug Development

Tooba Gholikhani (2024)

Single-stranded nucleic acids can fold and create unique 3-dimensional structures when interacting with other molecules. The unique structure can achieve high specificity and affinity for the particular target. Synthetic oligonucleotide binding a

23-06-2024
Extraction Techniques Used for the Removal of Pharmaceuticals from Environmental Samples

Mustafa Soylak (2024)

The existence of pharmaceuticals in the ecosystem originating from human activities has to pay more scientific interest during the past decades due to the concerns about their joint ecological effects in flora and fauna and by the extent in human hea

23-06-2024
An Overview of Cutaneous Wounds and the Beneficial Roles of Medicinal Plants in Promoting Wound Healing

Nura Muhammad Umar (2024)

It is undeniable that many patients worldwide suffer from various types of wounds, especially chronic wounds. The complex and intricate process of wound healing has a severe impact on the patient’s quality of life as well as causing an economic

23-06-2024
Clinical Efficacy of Hydroxychloroquine or Chloroquine in Patients with COVID-19: An Umbrella Review

Kavous Shahsavarinia (2024)

Background: Many of the known coronaviruses cause a wide range of respiratory infections in humans, and the novel coronavirus is no exception to this rule. Although no drug has yet been discovered to prevent or treat this disease, chloroquine (CQ

23-06-2024
Effect of Garlic (Allium sativum) Extract on Salivary Streptococcus mutans: A Systematic Review and Meta-Analysis

Mostafa Torbati (2024)

Background: Oral and dental diseases are among the common health conditions which can have different effects on the individuals’ health and quality of life. The objective of this study was to examine the effect of garlic (Allium sativum) extrac

23-06-2024
Recent Progress in Development of Polo Like Kinase 1 Inhibitors: Efforts So Far

Ramesh Sawant (2024)

Polo-like kinase 1(Plk1) plays an essential role in inhibiting cell proliferation and comes under the family of serine/threonine-protein kinase, which is a particular target for cancer therapy. In some clinical studies, Plk1 has been identified a

23-06-2024
PREPARATION AND EVALUATION OF DOLUTEGRAVIR SOLID DISPERSIONS

SUNDEEP MUPPARAJU (2024)

Objective: The current work mainly focuses on solubility enhancement of dolutegravir which is a BCS (Biopharmaceutical Classification System) class-II drug using various excipients. Methods: Solid dispersions of dolutegravir were prepared by solve

23-06-2024
ENHANCEMENT OF SOLUBILITY AND DISSOLUTION RATE OF ACETYLSALICYLIC ACID VIA CO-CRYSTALLIZATION TECHNIQUE: A NOVEL ASA-VALINE COCRYSTAL

SHANTHALA H. K. (2024)

Objective: This study aims to synthesize acetylsalicylic acid (ASA) cocrystals using valine as a coformer via a co-crystallization technique to increase the solubility and dissolution rate of ASA. Methods: The ASA-valine cocrystal (1:1 molar ratio

23-06-2024
FABRICATION OF NANO CLAY INTERCALATED POLYMERIC MICROBEADS FOR CONTROLLED RELEASE OF CURCUMIN

DHARMENDER PALLERLA (2024)

Objective: The objective of this study was to formulate and evaluate the Curcumin (CUR) encapsulated sodium alginate (SA)/badam gum (BG)/kaolin (KA) microbeads for controlled drug release studies. Methods: The fabricated microbeads were characteriz

23-06-2024
FABRICATION OF SODIUM ALGINATE/GUM GHATTI IPN MICROBEADS INTERCALATED WITH KAOLIN NANO CLAY FOR CONTROLLED RELEASE OF CURCUMIN

D. GANESH (2024)

Objective: The objective of this study is to fabricate sodium alginate (SA)/gum ghatti (GG) microbeads intercalated with Kaolin (KA) nano clay for the sustained release of curcumin (CUR). Methods: The microbeads were prepared by a simple ionotropi

23-06-2024
PRONIOSOMAL GEL MEDIATED TRANSDERMAL DELIVERY OF GLIBENCLAMIDE AND ATENOLOL COMBINATION: EXVIVO AND PHARMACODYNAMIC STUDIES

P. ANITHA (2024)

Objective: The objective of the present work was to develop an optimized dosage form for treating comorbidity in combination and evaluate it for its pharmacodynamic performance in male Wistar albino rats. Methods: Transdermal proniosomal gel for

23-06-2024
FORMULATION, OPTIMIZATION AND IN VITRO EVALUATION OF 5-FLUOROURACIL LOADED LIQUORICE CRUDE PROTEIN NANOPARTICLES FOR SUSTAINED DRUG DELIVERY USING BOX-BEHNKEN DESIGN

GEETHA V. S. (2024)

Objective: To formulate, optimize and evaluate 5-fluorouracil loaded liquorice crude protein nanoparticles for sustained drug delivery using BoxBehnken design. Methods: 5-fluorouracil (5-FU) loaded liquorice crude protein (LCP) nanoparticles were p

23-06-2024
REVIEW ON EVALUATING THE ROLE OF NSAIDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE

KRISHNENDU P. R. (2024)

Recently, several studies have been reported that nonsteroidal anti-inflammatory drugs can fight against neurodegenerative disorders by various mechanisms. Currently, available therapies of neurodegenerative disorders (NDs) provide only symptomatic

23-06-2024
STUDY OF ISOTONICITY AND OCULAR IRRITATION OF CHLORAMPHENICOL IN SITU GEL

INSAN SUNAN KURNIAWANSYAH (2024)

Objective: The objective of this study was to find out the isotonicity of chloramphenicol ophthalmic in situ gel and to know the irritating effect of its in the eyes of test animals, so it can be to maximize absorption of the drug in the eye, minim

23-06-2024
EXPERIMENTAL DEVELOPMENT AND MOLECULAR DOCKING: NANOSTRUCTURED LIPID CARRIERS (NLCs) OF COENZYME Q10 USING STEARIC ACID AND DIFFERENT LIQUID LIPIDS AS LIPID MATRIX

NI LUH DEWI ARYANI (2024)

Objective: To develop coenzyme Q10 (co-Q10) nanostructured lipid carriers (NLCs) using stearic acid (SA) and various liquid lipids with different lipophilicity as well as highlights the use of in silico studies for predicting and elucidating the in

23-06-2024
COMPARATIVE DISSOLUTION STUDIES OF WARFARIN SODIUM TABLETS: INFLUENCE OF AGITATION RATE, DISSOLUTION MEDIUM, AND USP APPARATUS

JOSE RAUL MEDINA LOPEZ (2024)

Objective: The aim of this study was to carry out comparative dissolution studies with warfarin sodium reference tablets under the hydrodynamic environments generated by the USP basket and paddle apparatus and flow-through cell using different agit

23-06-2024
SLOW QUASIKINETIC CHANGES IN WATER-LACTOSE COMPLEXES DURING STORAGE

M. A. MOROZOVA (2024)

Objective: To investigate kinetic changes in the spectral characteristics by Fourier Transform Infrared spectroscopy (FTIR) of water-lactose complexes (SMC), derived during the manufacturing process of the drug, containing release-active forms of a

23-06-2024
DETERMINATION OF CARBOHYDRATES CONTENT IN GENTIANA CRUCIATA L. BY GC/MS METHOD

LILIIA BUDNIAK (2024)

Objective: Thus, the aim of our research was to determine the qualitative composition and quantitative content of carbohydrates in the studied plant material with the prospect of its application as a medicinal plant raw material. Methods: The car

23-06-2024
AN UPDATED REVIEW ON THE APPLICATION OF DENDRIMERS AS SUCCESSFUL NANOCARRIERS FOR BRAIN DELIVERY OF THERAPEUTIC MOIETIES

SARANYA SASI (2024)

It’s been nearly 100 y of effort to study the organization and role of the blood brain-barrier and still, we strive to find better techniques to overcome this barrier to deliver the drugs to the brain effectively with reduced systemic side effect

23-06-2024
THE COSMETIC EFFECTS OF VARIOUS NATURAL BIOFUNCTIONAL INGREDIENTS AGAINST SKIN AGING: A REVIEW

WISAM NASER (2024)

Nutricosmetics have emerged to indicate the health benefits of the products that create beauty from inside to outside. Nutricosmetic is the latest trend in the beauty industry. Cosmeceuticals are commonly used in skincare regimens to maintain healt

23-06-2024
CHITOSAN NANOPARTICLES MEDIATED DELIVERY OF MIR-106B-5P TO BREAST CANCER CELL LINES MCF-7 AND T47D

LEONNY DWI RIZKITA (2024)

Objective: The development of nanomedicine, such as miRNA transfection to cancer cells, has widely gained interest in the past decade. Unfortunately, miRNA tends to decay easily by the cellular enzymatic process and requires a carrier. As a cationi

23-06-2024
DRUG RELEASE CONTROL AND ENHANCEMENT USING CARRIERS WITH DIFFERENT CONCENTRATIONS OF CAPMUL® MCM C8

MOHAMMAD F. BAYAN (2024)

Objective: The main aim of this study was to design a drug carrier capable to control and enhance the release of poorly water soluble drugs. Methods: Three polymeric formulations, based on poly (2-hydroxyethyl methacrylate) and loaded with differen

23-06-2024
HPLC DETERMINATION OF SILDENAFIL IN TABLETS

MIGLENA SMERIKAROVA (2024)

Objective: The popularity of Sildenafil, the widespread distribution of various products and dietary supplements with added synthetic drugs, requires reliable analysis methods. This research study aimed to develop a simple isocratic HPLC method for

23-06-2024
DETAILED VIEW ON REPURPOSED DRUGS, TRACKING OF VACCINES,AND BRIEF VIEW ON PROPHYLACTIC NANOMEDICINES AS AN ALTERNATIVE APPROACH AND PATIENT CARE FOR COVID-19

KRISHNANJANA S. NAIR (2024)

In December 2019, a rare case of pneumonia was reported in Wuhan, China. This was later analyzed and known to have similar characteristics as viral pneumonia caused by a novel coronavirus. Later, on 11 February 2020, the World Health Organization (

23-06-2024
A REVIEW ON POLOXAMER AND HYDROXY PROPYL METHYL CELLULOSE COMBINATION AS THERMORESPONSIVE POLYMERS IN NOVEL OPHTHALMIC IN SITU GEL FORMULATION AND THEIR CHARACTERIZATION

INSAN SUNAN KURNIAWANSYAH (2024)

Poor bioavailability is one of the most significant problems in the delivery of the ocular drug system. Ophthalmic ointments, solutions and suspensions are the most frequently used dosage forms to treat ocular disease, and their effectiveness as a

23-06-2024
PHARMACY PROFESSIONS IN INDIA DURING COVID-19 PANDEMIC: PRESENT STATUS, FUTURE CHALLENGES AND A WAY FORWARD

VIGNESH M. (2024)

People in every country became exposed to COVID-19 pandemic and cannot able to find a right solution and strategies to overcome from it. Pharmacy is the most important, dynamic and versatile health care profession in the world, whereas its scope an

23-06-2024
MUCOADHESIVE POLYMERIC FILMS OF ACYCLOVIR PRONIOSOMES FOR BUCCAL ADMINISTRATION

DEEKSHA U. SUVARNA (2024)

Objective: The aim of the present work was to formulate and evaluate proniosomes of the poorly soluble drug, acyclovir incorporated in mucoadhesive polymeric films for improved buccal mucosal permeability of the drug while achieving prolonged relea

23-06-2024
NOVEL DELIVERY APPROACHES OF CO-TRIMOXAZOLE FOR RECREATING ITS POTENTIAL USE-A REVIEW

ROHITAS DESHMUKH (2024)

Co-trimoxazole appropriates to category of broad-spectrum antimicrobial. They are active upon administration in vitro against an extensive collection of microorganisms. Their application in medical field has roughly spanned over decade now. There ar

23-06-2024
TOPICAL DRUG DELIVERY OF GOSSYPIN FROM PRONIOSOMAL GEL FORMULATIONS: IN VITRO EFFICACY AGAINST HUMAN MELANOMA CELLS

JAMPALA RAJKUMAR (2024)

Objective: This work aimed to establish and formulate the gossypin proniosomal gel drug delivery system. Methods: Gossypin-loaded proniosomal gels (GPG) was prepared using specific non-ionic surfactants (Spans), followed by particle size (PS), en

23-06-2024
RP-HPLC (STABILITY-INDICATING) BASED ASSAY METHOD FOR THE SIMULTANEOUS ESTIMATION OF DORAVIRINE, TENOFOVIR DISOPROXIL FUMARATE AND LAMIVUDINE

V. L. N. BALAJI GUPTA TIRUVEEDHI (2024)

Objective: In this study, a RP-HPLC (stability-indicating) based assay method for the estimation of doravirine (DRV), tenofovir disoproxil fumarate (TFF) and lamivudine (LMV) simultaneously in the tablets was described. Methods: The simultaneous

23-06-2024
SYSTEMATIC REVIEW: COCRYSTAL AS EFFORTS TO IMPROVE PHYSICOCHEMICAL AND BIOAVAILABILITY PROPERTIES OF ORAL SOLID DOSAGE FORM

IYAN SOPYAN (2024)

Water solubility and low bioavailability of active pharmaceutical ingredients are some of the main challenges in the process of developing new drugs, especially drugs in oral solid dosage forms. One way to improve drug solubility is the principle o

23-06-2024
CORRELATION OF GENETIC POLYMORPHISM IN UGT1A1, SLCO1B1, NAT2, AND CYP2E1 WITH HEPATOTOXICITY

GITA WIDI SETYOWATI (2024)

Tuberculosis (TB) has been identified as one of the most highly infectious diseases in the world. Tuberculosis can be identified as pulmonary or extrapulmonary. Therapy for TB is a combination of several drugs in one treatment. The effectiveness an

23-06-2024
A VALIDATED RP-HPLC METHOD FOR IMPURITY PROFILING OF SODIUM NITROPRUSSIDE IN INJECTION DOSAGE FORM

MURALI KRISHNAM RAJU P. (2024)

Objective: The main objective of this research work is to develop and validate a single reverse-phase high-performance liquid chromatography (RPHPLC) method. This method should be capable of quantifying all the known, as well as other possible degrad

23-06-2024
NOVASOME: A PIONEERING ADVANCEMENT IN VESICULAR DRUG DELIVERY

ASLAM ABDUL RAHIMAN C. A. (2024)

Pharmaceutical research has developed various new types of innovative forms of drug delivery. Advancement in current drug delivery methods has led to the development of numerous new revolutionary technologies that support safe and efficient formula

23-06-2024
HYDROGEL: RESPONSIVE STRUCTURES FOR DRUG DELIVERY

MALLIKARJUN P. N. (2024)

Hydrogels are water-swollen 3D networks made of polymers, proteins, small molecules, or colloids. They are porous in structure and entrap/encapsulate large amounts of therapeutic agents and biopharmaceuticals. Their unique properties like biocompat

23-06-2024
IN SITU GEL POLYMERS: A REVIEW

MOUNIKA KONATHAM (2024)

In situ gels have become one of the most prominent and accessible systems. These systems have several advantages like simple manufacturing, easy to use, improved adherence, and patient comfort by minimizing drug administration frequency by its uniq

23-06-2024
DEVELOPMENT AND CHARACTERISATION OF FAST DISSOLVING FILM OF POORLY WATERSOLUBLE DRUG LURASIDONE HYDROCHLORIDE

ANAGHA PRABHU (2024)

Objective: The objective of the present work was to formulate and evaluate a fast-dissolving oral film of lurasidone hydrochlorideused as an atypical antipsychotic for the treatment of schizophrenia capable of providing faster onset of action. Met

23-06-2024
FORMULATION, OPTIMIZATIONAND EVALUATION OF SUBLINGUAL FILM OF ENALAPRIL MALEATE USING 3 2 FULL FACTORIAL DESIGN

SATYAJIT SAHOO (2024)

Objective: The purpose of this investigation was to formulate, optimize and evaluate sublingual film of Enalapril maleate for rapid management of Hypertension. Methods: Sublingual films were prepared by solvent casting method. Present investigati

23-06-2024
BIOWAIVER STUDY OF IMMEDIATE RELEASE GLIMEPIRIDE TABLETS

SIHAM ABDOUN (2024)

Objective: Demonstrating therapeutic equivalency regarding the efficacy and safety among originator products and generics is a key step in permitting the marketing of generic products. The study aimed to evaluate the bioequivalence of five differen

23-06-2024
MICROFLUIDIC DEVICES AS A TOOL FOR DRUG DELIVERY AND DIAGNOSIS: A REVIEW

ISHA SHARMA (2024)

Microfluidic devices are a good example of the collaboration of chemical, biological, and engineering sciences. Microfluidic devices emerge as an in fluent technology which provides an alternative to conventional laboratory methods. These devices a

23-06-2024
IMPORTANCE OF NANOCARRIERS AND PROBIOTICS IN THE TREATMENT OF ULCERATIVE COLITIS

VANDANA THAKUR (2024)

Ulcerative colitis (UC) is an inflammatory chronic disease primarily affecting the colonic mucosa; the extent and severity of colon involvement are variable. Ulcerative colitis is identified by mucus diarrhea, tenesmus, bowel distension, and anemia

23-06-2024
Translation, Cultural Adaptation, and Validation of the Multidimensional Scale of Perceived Social Support for Cancer Patients in Indonesia

Didik Setiawan (2024)

The social support is increasingly accepted as an important factor that influences the wellness of a human being, particularly people with chronic diseases. This study translates and validates the quantitative questionnaire that has been develope

23-06-2024
Kalkon dan Potensinya sebagai Antikanker : Literatur Review

Bilqis Na’ilah Almattin (2024)

Salah satu senyawa yang memiliki potensi sebagai antikanker adalah Kalkon. Senyawa kalkon (1,3-difenil-2-propena-1-on) memiliki satu atom karbon a,ß-tak jenuh. Pada cincin A terdapat gugus metil, etil atau alkil sedangkan pada cincin B terdapat gugu

23-06-2024
Evaluasi Kuantitatif Dan Total Biaya Penggunaan Antibiotik Pada Periode Sebelum Dan Selama Pandemi Covid-19 Di RSUP Dr. Hasan Sadikin Bandung

Ilman Silanas (2024)

Pandemi COVID-19 telah meningkatkan terapi antibiotik empirik . Terapi empirik dipilih untuk mengatasi koinfeksi bakteri pada pasien COVID-19. Peningkatan kuantitas penggunaan antibiotik akan meningkatkan resistensi dan biaya jika tidak dilakukan

23-06-2024
Identifikasi Potentially Inappropriate Medication (PIM) Berdasarkan Beers Criteria Pada Pasien Covid-19 di RSUD Undata Provinsi Sulawesi Tengah

Arya Dibyo Adisaputra (2024)

Potentially Inappropriate Medication (PIM) atau lebih dikenal dengan penggunaan terapi obat yang berpotensi tidak tepat ialah pengobatan berkaitan dengan risiko efek samping obat. Penelitian ini berfokus pada jumlah penggunaan terapi obat yang berp

23-06-2024
Penerapan Metode Workload Indicator Staffing Need untuk Evaluasi Kebutuhan Tenaga Kefarmasian: Studi Kasus di Depo Farmasi Rawat Jalan Peserta Asuransi Jaminan Kesehatan Nasional pada Sebuah Rumah Sakit Swasta di Kota Bandung

Patria Pari Agnes Ago Ana Sombo (2024)

Pemerintah Indonesia telah menyediakan Jaminan Kesehatan Nasional (JKN) untuk meningkatkan akses masyarakat ke fasilitas kesehatan termasuk rumah sakit. Diperlukan penilaian sumber daya manusia (SDM) yang memadai di setiap unit rumah sakit untuk da

23-06-2024
Analisis Utilitas Biaya Annual Population-Based Screening Dibandingkan Dengan Opportunistic Screening Diabetes Melitus Di Indonesia Menggunakan Markov Model

Erick Budiawan (2024)

Prevelensi Diabetes Melitus (DM) di Indonesia semakin meningkat dari tahun ke tahun dan berdampak pada tingginya biaya perawatan. Salah satu upaya pencegahan DM yang dapat dilakukan adalah melalui deteksi dini atau skrining. Saat ini di Indonesia

23-06-2024
Perbandingan Efek Samping Antiplatelet Tunggal dan Ganda terhadap Gastrointestinal pada pasien Strok Iskemik

Harni Sartika Kamaruddin (2024)

Antiplatelet merupakan terapi yang digunakan secara tunggal maupun ganda untuk strok iskemik. Namun, pengobatan antiplatelet dapat memberikan risiko efek samping terhadap gastrointestinal. Penelitian ini dilakukan bertujuan untuk membandingkan efek

23-06-2024
Pola Penggunaan Antibiotik Pada Pasien Pneumonia Dewasa di Instalasi Rawat Inap RSUD Provinsi NTB

Lina Sugiani (2024)

Pneumonia merupakan peradangan akut pada paru yang sebagian besar disebabkan oleh bakteri dan merupakan penyebab kematian terbesar terutama di negara berkembang. Terapi utama pneumonia dengan penyebab bakteri adalah antibiotik. Penelitian ini ber

23-06-2024
Korelasi Tingkat Keparahan Efek Samping Obat Regimen Leucovorin Calcium (Folinic Acid), Fluorouracil, dan Oxaliplatin dengan Kualitas Hidup Pasien Kanker Kolorektal

Rinto Susilo (2024)

Adanya kejadian efek samping obat (ESO) pada pasien kemoterapi dapat memberikan resiko pada penurunan kualitas hidup. Penelitian ini bertujuan untuk mengetahui korelasi tingkat keparahan efek samping obat regimen leucovorin calcium (folinic acid)

23-06-2024
Analisis Efektivitas Biaya Escitalopram dan Fluoksetin Dibandingkan dengan Sertralin untuk Gangguan Depresi Mayor di Salah Satu Klinik di Kota Bandung

Sani A. R. Lestari (2024)

Gangguan depresi mayor menjadi kontributor utama beban penyakit global yang memengaruhi jutaan masyarakat dari segala usia di seluruh dunia. Di berbagai negara, escitalopram dinilai lebih efektif secara biaya dibandingkan dengan selective seroton

23-06-2024
Antihyperlipidemic Effect of Bitter Melon Extract (Momordica Charantia L.) in Wistar Rats

Evi Sovia (2024)

The use of alternative medicine, especially medicinal plants to treat various diseases including hyperlipidemia has increased over the last few decades in most countries around the world. Bitter melon (Momordica charantia) contains active ingredi

23-06-2024
Bakteri Utama Penyebab Kejadian Luar Biasa Keracunan Pangan

Mutiara Apriliansyah (2024)

Kejadian Luar Biasa (KLB) Keracunan Pangan (KP) merupakan kejadian saat dua orang atau lebih menderita sakit dengan gejala yang sama atau hampir sama setelah mengonsumsi pangan yang terbukti sebagai sumber keracunan berdasarkan epidemiologinya. K

23-06-2024
Review Penggunaan Antivirus Berdasarkan Penatalaksanaan Covid-19 pada Periode Maret 2020-Desember 2022

R.A.Rogayah Effendy (2024)

Coronavirus disease 2019 (Covid-19) telah menjadi tantangan kesehatan dunia saat pandemi Covid-19. Salah satu strategi terapeutik difokuskan pada pengendalian infeksi, yaitu dengan penggunaan antivirus. Review ini difokuskan pada tinjauan literat

23-06-2024
The Effect of N-Acetylcysteine on Glomerulus Filtration Rate in Patients with Chronic Kidney Disease Post Percutaneous Coronary Intervention

Putu Rika Veryanti (2024)

The use of contrast for percutaneous coronary intervention (PCI) procedures in chronic kidney disease (CKD) patients can worsen kidney function. N-Acetylcysteine is widely used as a preventive therapy for contrast-induced nephropathy (CIN). Howev

23-06-2024
Penggunaan Bronkodilator Tunggal atau Bersama Kortikosteroid dapat Memperbaiki Parameter Sesak, w/h, dan r/h pada Pasien Rawat Inap dengan PPOK Eksaserbasi Akut di RS.X di Jember Tahun 2018

Ika Puspita Dewi (2024)

Penyakit Paru Obstruktif Kronik (PPOK) merupakan penyebab utama kematian ke-empat di dunia yang ditandai dengan adanya hambatan aliran udara yang bersifat progresif dan berkaitan dengan respon inflamasi kronis pada saluran napas dan atau paru-par

23-06-2024
Khasiat dan Keamanan Kapsul Ekstrak Daun Salam, Sambiloto, Kayu Manis dan Temulawak sebagai Jamu Antihiperglikemia: Studi Klinis dengan Desain Paralel, Random, dan Tersamar Tunggal

Ulfa Fitriani (2024)

Penyakit diabetes merupakan penyakit non-infeksi yang menjadi perhatian dunia. Penggunaan tanaman obat sebagai terapi diabetes banyak dijumpai. Penelitian sebelumnya terhadap rebusan ramuan jamu antihiperglikemia yang mengandung daun salam, sambi

23-06-2024
Korelasi Kadar Serum Vitamin D terhadap Derajat Keparahan Penyakit Infeksi Covid-19: Sebuah Literatur Review

Devyani D. Wulansari (2024)

Dalam beberapa tahun terakhir, penyakit infeksi yang disebabkan oleh virus menjadi salah satu masalah terbesar bagi kesehatan global, termasuk infeksi coronavirus disease 2019 (Covid-19). Covid-19 merupakan penyakit yang disebabkan oleh severe ac

23-06-2024
Infuence of Therapy Compliance Using Medication Possession Ratio Method for Patients with Metabolic Syndrome

Christianus H. Setiawan (2024)

Metabolic syndrome is still a major problem in developing countries and it has an association with high blood pressure, blood glucose, and lipid profle abnormalities, which can cause cardiovascular disease. This indicates that it is important to

23-06-2024
Efek Penggunaan Antibiotik yang Rasional terhadap Perbaikan Klinis pada Pasien Anak Dirawat Inap dengan Pneumonia

Mega Damayanti (2024)

Pneumonia merupakan salah satu infeksi saluran pernapasan akut yang menempati urutan kedua sebagai penyebab kematian pada anak-anak di Indonesia. Penggunaan antibiotik yang rasional harus menjadi perhatian karena berperan sangat penting dalam pen

23-06-2024
Efek Polimorfsme Gen Enzim Pemetabolisme Obat terhadap Kadar Rivaroxaban: Sebuah Kajian Naratif

Sarah P. Atmaja (2024)

Rivaroxaban merupakan agen antikoagulan yang mengalami biotransformasi via liver dengan melibatkan peran dari CYP3A4/5 (18%); CYP2J2 (14%) dan sisanya melalui CYP independent hydrolytic cleavage (14%). Polimorfsme yang terjadi pada gen pemetaboli

23-06-2024
Precautionary Measures, Attitude, and Productive Activities of Students in West Java Province, Indonesia, during Covid-19 Pandemic

Rimadani Pratiwi (2024)

The Covid-19 pandemic has been ongoing for approximately one year, hence, several activities must be carried out remotely from home. Studying from home for every level of education has its challenges, specifcally for university students in terms

23-06-2024
Obat Off-label pada Pasien Pediatri Rawat Jalan: Penelitian Observasi Retrospektif di RSUD Dr. H. Abdul Moeloek Lampung

Cheri F. A. Dera (2024)

Informasi pada pelabelan obat data khasiat dan keamanan pada populasi anak terbatas. Keterbatasan informasi mngakibatkan peresepan obat off-label banyak terdapat pada pasien pediatri. Penelitian ini bertujuan untuk mendapatkan gambaran penggunaan

23-06-2024
A Comparison of Potentially Inappropriate Medications Identifcation Using Beers and STOPP Criteria in Hospitalized Geriatric Patients in Jakarta

Daniek Viviandhari (2024)

Adverse Drug Events (ADE) are closely related to Potentially Inappropriate Medications (PIMs) among the elderly, and can cause an increase in morbidity, mortality, and medical cost. The tools often used to assess PIMs include Beers and Screening

23-06-2024
Evaluasi Pola Peresepan Pasien Geriatri di RSUD Dr. Soedarso Pontianak Berdasarkan Beers Criteria

Sarah M. Sasf (2024)

Pasien geriatri adalah pasien lanjut usia yang menderita multipenyakit serta gangguan akibat penurunan fungsi fsiologis; perubahan fsiologis menyebabkan respon terhadap obat menjadi berubah. Beers Criteria dapat digunakan sebagai acuan dalam pemb

23-06-2024
Effectiveness and Safety of Baricitinib as a Covid-19 Drug Candidate: A Systematic Review

Yayuk S. Rahayu (2024)

Baricitinib is an approved selective JAK1/JAK2 inhibitor that can potentially inhibit IL-6 as the primary driver of COVID-19-related cytokine storm syndrome. Therefore, this study aimed to assess the effectiveness and safety of baricitinib therap

23-06-2024
Potensi Interaksi Obat di Ruang Rawat Intensif: Sebuah Studi Observasional di Salah Satu Rumah Sakit Kota Bandung

Ivan S. Pradipta (2024)

Ruang rawat intensif atau Intensive Care Unit (ICU) rumah sakit berperan dalam menangani pasien yang membutuhkan penanganan intensif. Perlunya intervensi pasien yang komprehensif dan cepat berpotensi menyebabkan kejadian interaksi obat dengan oba

23-06-2024
Perbandingan Efektivitas Aromaterapi Lavender dan Aromaterapi Rosemary terhadap Stres pada Dewasa

Ni Made Maharianingsih (2024)

Stres merupakan perubahan keadaan disebabkan oleh adanya tuntutan lebih berat. Stres terjadi pada semua usia, namun perubahan tanggung jawab pada dewasa menyebabkan usia ini rentan mengalami stres. Aromaterapi lavender dan rosemary merupakan arom

23-06-2024
Prediktor Respons Tolvaptan Sebagai Strategi Optimalisasi Terapi Pada Pasien Gagal Jantung: Kajian Naratif

Hindun W. Risni (2024)

Gagal jantung (GJ) merupakan kondisi tahap akhir dari semua penyakit jantung dan dikaitkan dengan mortalitas, morbiditas, dan pengeluaran kesehatan yang signifkan. Tolvaptan, antagonis reseptor V2, telah digunakan di berbagai negara sebagai terap

23-06-2024
Kemunculan Gen Mycobacterium tuberculosis dari Sampel Darah Pasien Pengobatan Tuberkulosis Fase Konversi Menggunakan PCR yang Tidak Terdeteksi dengan Evaluasi Pewarnaan Bakteri di Puskesmas Janti

Rehmadanta Sitepu (2024)

Fase konversi pada pengobatan tuberkulosis merupakan fase dilakukannya pemeriksaan terhadap pasien tuberkulosis untuk memastikan apakah pasien melanjutkan pengobatan ke tahap lanjutan atau mengulangi pengobatannya. Sayangnya, evaluasi yang dilaku

23-06-2024
Efektivitas Antibiotik Inhalasi pada Pasien Ventilator Associated Pneumonia: Kajian Sistematis dan Meta-Analisis

Beryl Bayanaka (2024)

Antibiotik inhalasi dapat menjadi tambahan dalam terapi ventilator associated pneumonia (VAP) karena menghantarkan antibiotik secara langsung ke dalam lokasi infeksi di paru-paru untuk menyediakan konsentrasi antibiotik yang adekuat di paru-paru,

23-06-2024
Efek Kualitas Pelabelan Terhadap Pengetahuan dan Kepatuhan Pasien Hipertensi di Mataram

I Gusti A. D. Mariati (2024)

Hipertensi merupakan penyakit kronis yang membutuhkan pengobatan jangka panjang, dengan kepatuhan menjadi suatu permasalahan utama. Label pada obat seringkali digunakan sebagai media informasi tertulis untuk mengoptimalkan penggunaan pengobatan d

23-06-2024
Analisis Perbandingan Kualitas Hidup Pasien Skizofrenia Fase Stabil pada Pengobatan Kombinasi Risperidon-Haloperidol dengan Kombinasi Klozapin-Risperidon-Haloperidol di Rumah Sakit Jiwa Provinsi Kalimantan Barat

Yusi Anggriani (2024)

Skizofrenia merupakan salah satu gangguan jiwa kompleks yang dapat menimbulkan beban berat bagi individu dan keluarga. Pengobatan skizofrenia perlu masa yang panjang dan menahun karena merupakan penyakit kronis yang berpotensi terjadi kekambuhan.

23-06-2024
Intervensi Farmakologi Sindrom Putus Obat pada Penyalahguna Opioid

Nisa Maria (2024)

Sindrom putus obat opioid terjadi setelah penghentian konsumsi opioid secara-tiba-tiba, dengan gejala seperti mata dan hidung berair, nyeri pada tulang atau sendi, ansietas, kondisi kedinginan atau kepanasan, dilatasi pupil, menguap, gangguan gas

23-06-2024
Karakteristik Klinik dan Pola Antibiotik pada Pasien Rawat Inap Coronavirus Disease 2019 di Rumah Sakit Wava Husada Malang

Ardiyatul I. Kelana (2024)

Coronavirus Disease 2019 (COVID-19) disebabkan oleh infeksi virus Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) yang mengakibatkan manifestasi klinik pneumonia. Pneumonia pada COVID-19 utamanya disebabkan virus, namun bakteri dapat

23-06-2024
Pengaruh Menulis Ungkapan Syukur dalam Buku Syukur Beta terhadap Tingkat Depresi Pasien Diabetes Melitus Tipe-2

Maria P. E. Rengga (2024)

Diabetes melitus (DM) menduduki peringkat ke-6 penyebab kematian di seluruh dunia (2015) dan termasuk 5 besar penyebab kematian di Indonesia. Pasien dengan DM memiliki risiko terdiagnosis depresi 1,4–3 kali. Penelitian terdahulu menunjukkan ter

23-06-2024
Clinical Pharmacist’s Role in Optimizing Therapy through Drug-Related Problems Identifcation

Liana Debora (2024)

Clinical pharmacists play an important role in a clinical setting as part of a team. Drug-related problem (DRP) is the main part pharmacist should focus on to achieve the optimal therapy for patients. Therefore, this study aimed to investigate th

23-06-2024
Rekomendasi Apoteker Komunitas Saat Menghadapi Permintaan Swamedikasi Diare yang Disertai Darah: Sebuah Survei di Wilayah Perkotaan Indonesia

Yustina Octafelia (2024)

Diare merupakan salah satu penyakit ringan yang banyak dijumpai di komunitas. Apoteker perlu memiliki kemampuan untuk memilah kasus diare yang dapat ditangani dengan obat bebas atau yang membutuhkan rujukan segera ke dokter, seperti kasus diare d

23-06-2024
Pemantauan Kadar Obat Antiepilepsi secara Farmakokinetika Terhadap Clinical Outcome pada Pasien Pediatrik

Masita W. Suryoputri (2024)

Tingginya prevalensi penggunaan obat antiepilepsi pada pediatrik akan meningkatkan risiko timbulnya efek samping dan efek toksik, sehingga perlu adanya pemantauan kadar obat. Pemantauan kadar obat dapat dilakukan secara farmakokinetika dengan men

23-06-2024
Evaluation of Quality of Life on Functional, Symptoms, and Global Health Status in Breast Cancer Patients among Chemotherapy Cycles with Cyclophosphamide-Doxorubicin-5Fluorouracil

Siti Saleha (2024)

Treatment of breast cancer with chemotherapy in several cycles has led to differences in patients' quality of life. One of the chemotherapy recommendations for breast cancer is CyclophosphamideDoxorubicin-5Fluorouracil (CAF). Therefore, this resear

23-06-2024
Luaran Humanistik Pasien Kanker Serviks yang Menggunakan Regimen Cisplatin-Vinkristin-Bleomisin

Suwendar (2024)

Luaran humanistik seperti kualitas hidup merupakan parameter yang sangat penting untuk menilai keberhasilan kemoterapi. Penelitian ini bertujuan untuk mengevaluasi dampak penggunaan regimen cisplatin-vinkristin-bleomisin pada kualitas hidup, sehi

23-06-2024
Efektivitas dan Keamanan Terapi Benzodiazepin pada Pasien Gangguan Ansietas dengan Riwayat Penyalahgunaan Obat

Ni Nyoman Y. Mendra (2024)

Gangguan ansietas merupakan salah satu gangguan mental yang paling banyak dijumpai. Beberapa faktor dapat memicu terjadinya gangguan ansietas, salah satunya adalah riwayat penyalahgunaan obat. Tatalaksana terapi pada pasien ansietas dengan riwaya

23-06-2024
Penggunaan dan Resistensi Antibiotik di Instalasi Rawat Intensif Rumah Sakit Umum Daerah di Bali: Studi Ekologikal selama 3 Tahun

Herleeyana Meriyani (2024)

Resistensi bakteri yang terjadi di Intensive Care Unit (ICU) disebabkan oleh banyak faktor, salah satunya adalah penggunaan dan pemilihan antibiotik yang tinggi dan selektif. Perlu dilakukan studi tentang tingkat penggunaan antibiotik dan resiste

23-06-2024
Implikasi Polimorfsme Gen CYP2A6 terhadap Penyakit Kardiovaskular

Preiffer A. Prasojo (2024)

Gen CYP2A6 merupakan penyandi enzim CYP2A6. Gen CYP2A6 diketahui memiliki tingkat polimorfsme yang tinggi sehingga menyebabkan terdapatnya variasi bentuk alel baik dalam bentuk aktif maupun alel inaktif. Adanya variasi bentuk alel ini selanjutnya

23-06-2024
The Beyond-Use Date Perception of Drugs in North Jakarta, Indonesia

Fonny Cokro (2024)

Beyond-Use Date (BUD) refers to the unsafe period of drug consumption and is calculated from the moment of opening the primary package. Meanwhile, Indonesia has no current related data, in terms of public awareness. Therefore, this research aims

23-06-2024
Analisis Beban Kerja Tenaga Teknis Kefarmasian di Instalasi Farmasi RSGM Universitas Padjadjaran dengan Metode Workload Indicators of Staffng Needs

Faisal Kuswandani (2024)

Salah satu tantangan dunia kesehatan adalah keseimbangan antara jumlah tenaga kerja dan beban kerja untuk mencapai kualitas, efektivitas, dan efsiensi. Hal ini masih sulit dicapai terutama di negara berkembang yang memiliki sumber daya dan anggar

23-06-2024
Peran Gen TNFRSF11B sebagai Pemicu Osteoporosis Sekunder pada Pasien Artritis Reumatoid

Nur A. Ali (2024)

Artritis reumatoid (AR) adalah kelainan autoimun sistemik yang menyebabkan peradangan luas dan persisten pada lapisan sendi sinovial. Pasien dengan AR memiliki risiko lebih besar terkena osteoporosis sekunder. Osteoporosis (OP) sekunder adalah ko

23-06-2024
Respon Terapi Community Acquired Pneumonia pada Geriatri: Tinjauan Kasus di Intensive Care Unit

Widyati (2024)

Pneumonia komunitas adalah salah satu masalah yang semakin meningkat di populasi lanjut usia. Berbagai faktor yang terkait dengan penuaan, seperti komorbiditas, status gizi dan disfungsi menelan telah terlibat dalam peningkatan Community Acquired

23-06-2024
Adverse Event Sindroma Metabolik Kombinasi Terapi Risperidon dan Klozapin pada Pasien Skizofrenia di Rumah Sakit Jiwa Magelang

Gilang R. Al Farizi (2024)

Kombinasi risperidon dan klozapin pada pasien skizofrenia dapat menyebabkan adverse drug event peningkatan body mass index (BMI), tekanan darah sistolik, dan tekanan darah diastolik seiring lamanya terapi. Penelitian ini bertujuan untuk mengident

23-06-2024
Efek Ekstrak Angkak dalam Menghambat Proliferasi Sel Kanker Prostat dan Payudara

TIANA MILANDA (2024)

Kanker payudara dan prostat masih menjadi kasus prevalensi tertinggi hingga saat ini, untuk itu diperlukan beberapa alternatif terapi yang berasal dari bahan alam dengan efek samping yang relatif rendah. Salah satu bahan alam yang memiliki aktivi

23-06-2024
Hubungan Derajat Celah Langit-Langit dengan Keadaan Telinga Tengah Berdasarkan Timpanogram pada Pasien Celah Langit-Langit

Shinta F. Boesoirie (2024)

Celah langit-langit dan bibir sering terjadi akibat kegagalan penyatuan langit-langit dan bibir selama masa perkembangan janin. Sekitar 90% penderita celah langit-langit akan mengalami gangguan telinga tengah dan menimbulkan gangguan pendengaran.

23-06-2024
Efek Proteksi Proflaksis Isoniazid terhadap Infeksi Tuberkulosis pada Pasien HIV di Rumah Sakit Pengayoman Cipinang

Nurftri Bustamam (2024)

Tuberkulosis (TB) merupakan infeksi oportunistik yang menjadi penyebab utama kematian pada pasien human immunodefciency virus (HIV). Oleh karenanya, perlu upaya pencegahan infeksi TB melalui pemberian proflaksis isoniazid (INH) kepada pasien HIV.

23-06-2024
Reaksi Obat yang Tidak Diharapkan dari Penggunaan Teoflin akibat Interaksi dengan Obat Penghambat Enzim Sitokrom P450 1A2: Laporan Kasus

Ulvi N. Rista (2024)

Teoflin merupakan bronkodilator dengan rentang konsentrasi terapetik sempit dan memiliki variabilitas antarindividu secara farmakokinetik. Klirens teoflin dipengaruhi oleh usia, fungsi hati, dan interaksi obat. Kami laporkan sebuah kasus anak usi

23-06-2024
Sacubitril/Valsartan: The Role of Neprilysin Pathway in Heart Failure

Sidhi L. Purwowiyoto (2024)

Neprilysin (NEP) is an enzyme present in several body cells and is involved in the degradation of natriuretic peptides (NPs), bradykinin (BK), and adrenomedullin (ADM). Furthermore, sacubitril/ valsartan (LCZ696), the frst agent of Angiotensin Rec

23-06-2024
Evaluasi Kuantitatif Penggunaan Antibiotik di Ruang Perawatan Airlangga dan Peta Kuman RSUD Kanjuruhan Malang Periode Juli-Desember 2018

Wirda Anggraini (2024)

Antibiotik merupakan salah satu obat yang paling banyak dikonsumsi secara luas di tempat layanan kesehatan. Tingginya jumlah penggunaan antibiotik yang tidak tepat dapat mengakibatkan terjadinya resistensi, efek samping dan biaya rumah sakit yang

23-06-2024
Potensi Tanaman Herbal Antidiabetes untuk Minuman Obat: Sebuah Literatur Review

Yulin Prisdiany (2024)

Jumlah kasus dan prevalensi diabetes terus meningkat selama beberapa dekade terakhir. Pada tahun 2012, diabetes menyebabkan 1,5 juta kematian. Seiring berkembangnya pengetahuan, saat ini tanaman herbal lebih banyak digunakan sebagai bahan obat. S

23-06-2024
Profl Proteinuria dan Tekanan Darah pada Pasien Preeklampsia Berat yang menggunakan Antihipertensi

Nurmainah (2024)

Preeklampsia berat sering terjadi pada ibu hamil. Pengobatan preeklampsia berat dapat dilakukan dengan pemberian antihipertensi untuk mencegah penyakit serebrovaskular dan kematian. Penelitian ini bertujuan untuk mendeskripsikan profl penurunan p

23-06-2024
Perbandingan Self-Report dengan Caregiver-Report mengenai Health-Related Quality of Life Anak dengan Talasemia Mayor Usia 8–12 Tahun

Putu G. P. R. Mudita (2024)

Penyakit kronis seperti talasemia telah diketahui memengaruhi kualitas hidup terkait kesehatan anak-anak. Jika anak belum mampu menilai kondisi kesehatannya sendiri, penilaian biasanya dilakukan oleh caregiver, terutama orang tua. Hanya saja, beb

23-06-2024
Drug Utilization Evaluation Anti Edema Otak pada Pasien Strok Hemoragik di Rumah Sakit Bethesda Yogyakarta

Viktoria M. Chyntia (2024)

Strok hemoragik adalah subtipe stroke yang menyebabkan tingginya mortalitas dan morbiditas. Edema otak adalah salah satu kontributor yang menjadi penyebab kematian. Penelitian ini bertujuan untuk mengevaluasi rasionalitas penggunaan anti edema ot

23-06-2024
Artikel Review: Interaksi Silang Pensinyalan WNT dan TGF-? pada Kanker Paru dengan MikroRNA sebagai Mayoritas Regulator

Nita Rahmasari (2024)

Posisi pertama untuk kejadian dan mortalitas kanker paru di dunia saat ini masih menjadi tantangan untuk menemukan dan mengembangkan terapi potensial bagi pasien kanker paru. Pemahaman pada tingkat molekular mengenai progres tumor pada kanker san

23-06-2024
Studi Pola Pemberian Artemisinin-Based Combination Therapy pada Pasien Malaria di RSUD Supiori Papua

Sandra J. Parambang (2024)

Malaria merupakan salah satu penyakit dengan prevalensi tinggi di Indonesia. Data Riset Kesehatan Dasar (Riskesdas) tahun 2018 menunjukkan prevalensi populasi malaria berdasarkan riwayat pemeriksaan darah tertinggi di Indonesia pada tahun 2013–

23-06-2024
Analisis Tarif INA-CBGs Pasien Hipertensi Rawat Inap di Rumah Sakit Umum Daerah Panembahan Senopati

Anis F. Nilansari (2024)

Angka pengidap hipertensi pada tahun 2018 sebesar 34,1?ri penduduk Indonesia. Profl data kesehatan Indonesia menyebutkan bahwa secara nasional terjadi peningkatan prevalensi hipertensi dari 25,8% pada tahun 2013 menjadi 34,1% pada tahun 2017. Bia

23-06-2024
Analisis Efektivitas-Biaya Terapi Kombinasi Metformin-Insulin dan Metformin-Sulfonilurea pada Pasien Rawat Jalan dengan Diabetes Melitus Tipe 2 di RSUPN Dr. Cipto Mangunkusumo

Fitriyani (2024)

Diabetes melitus tipe 2 (DMT2) diketahui sebagai salah satu masalah kesehatan yang memberikan beban ekonomi yang cukup besar pada sistem pelayanan kesehatan di seluruh dunia. Bervariasinya penggunaan terapi obat akan mengakibatkan adanya perbedaa

23-06-2024
Kejadian Demam Neutropenia pada Pasien Kanker Payudara setelah Menerima Regimen Kemoterapi TAC-G-CSF dan FAC di RSUP Dr. Hasan Sadikin Bandung

Nusaibah A. Hima (2024)

Demam neutropenia merupakan efek samping yang sering terjadi setelah kemoterapi. Demam neutropenia dapat menyebabkan penundaan dosis kemoterapi sehingga dapat mengurangi efektivitas terapi. Kejadian demam neutropenia setelah kemoterapi dapat dice

23-06-2024
Atypical Antipsychotic Induced Weight Gain in Schizophrenic Patients

Tetie Herlina (2024)

Atypical antipsychotics are widely prescribed and have the potential to cause weight gain, which may result in the development of metabolic syndrome. Also, it is important to monitor the use of atypical antipsychotic for metabolic disturbance. Th

23-06-2024
Analisis Efektivitas Lensa Intraokular Hidroflik dan Hidrofobik terhadap Posterior Capsule Opacifcation Pascaoperasi Katarak

Linda Dimyati (2024)

Komplikasi yang sering terjadi pascaoperasi katarak dengan implantasi lensa intraokular (LIO) adalah posterior capsule opacifcation (PCO) yang menyebabkan penurunan tajam penglihatan. PCO dapat terjadi beberapa bulan sampai beberapa tahun pascaop

23-06-2024
Artikel Review: Interaksi Silang Pensinyalan Wnt dan TGF-? pada Kanker Prostat

Luthf H. Siwi (2024)

Pertumbuhan dan perkembangan kanker dapat dipengaruhi oleh perubahan jalur pensinyalan. Dua pensinyalan utama yang mengalami perubahan pada kanker adalah pensinyalan Wnt dan TGF-?. Pensinyalan Wnt memiliki peran dalam proliferasi dan apoptosis se

23-06-2024
Effectiveness of Vitamin D and Vitamin B Supplementation Therapy in Diabetic Neuropathic Pain Standard Therapy

Rizaldy T. Pinzon (2024)

The chronic complication from diabetes mellitus (DM) is painful diabetic neuropathy, and the treatment with standard therapy is ineffcient. Furthermore, vitamin B combination is effective as a neuropathy treatment due to nerve repair acceleration

23-06-2024
Analysis of Antiemetic Premedication Administration Timing on Nausea and Vomiting Incidence among Breast Cancer Patients Receiving Chemotherapy

Mahardian Rahmadi (2024)

The risk factors affecting chemotherapy-induced nausea and vomiting (CINV) includes antiemetic premedication time pattern, and this study investigates the capability of enhancing this in breast cancer patients receiving high emetogenic chemothera

23-06-2024
Terapi Farmakologi Nyeri pada Amyotrophic Lateral Sclerosis

Indira D. Mahdayana (2024)

Amyotrophic lateral sclerosis (ALS) merupakan penyakit neurodegeneratif fatal yang memengaruhi motor neuron. Nyeri merupakan gangguan sensoris yang dapat timbul pada ALS dan gejala yang seringkali diremehkan dan diabaikan pada pasien dengan ALS.

23-06-2024
Acute Toxicity Test of Amomum cardamomum (Kapulaga) Seed Extract on Hepatic Trasaminase Enzyme in Winstar Rats

Ratih D. Yudhani (2024)

The herb frequently used as spices or remedies in the Indonesian community, with the seed as the most common part is kapulaga (Amomum cardamomum). According to earlier evidence, this possessed antibacterial, antifungal and several biological prop

23-06-2024
Hubungan antara Penggunaan Antihipertensi pada Pasien Preeklamsia terhadap Insidensi Asfksia Neonatal dan Berat Badan Lahir Rendah di RSUP Dr. Hasan Sadikin Bandung

Mutia F. Sitorus (2024)

Preeklamsia merupakan satu dari tiga penyebab utama kematian ibu hamil di Indonesia. Selain menyebabkan mortalitas dan morbiditas maternal, bayi yang dilahirkan dari pasien preeklampsia berisiko lahir dengan berat badan lahir rendah (BBLR) (<2500

23-06-2024
Analisis Efektivitas Biaya Terapi Kombinasi Amlodipin-Kandesartan dan Amlodipin-Ramipril pada Pasien Hipertensi dengan Komplikasi Diabetes Melitus Tipe 2 Rawat Jalan di RSUPN Dr. Cipto Mangunkusumo

Della R. Stiadi (2024)

Hipertensi dan diabetes melitus (DM) menjadi salah satu faktor risiko kejadian kardiovaskuler. Tidak terkontrolnya hipertensi dapat menyebabkan perburukan kesehatan dan ekonomi pada penderitanya. Kombinasi terapi antihipertensi dinilai adekuat un

23-06-2024
Pengetahuan, Sikap, dan Praktik Tenaga Kesehatan terhadap Penyakit Tuberkulosis: Sebuah Review

Idzni R. E. Yahya (2024)

Tuberkulosis (TB) merupakan salah satu penyakit infeksi yang menempati urutan ke-10 penyebab kematian tertinggi di dunia. Pada tahun 2018, diperkirakan 1,3 juta orang meninggal akibat penyakit TB. Tenaga kesehatan merupakan salah satu pekerjaan y

23-06-2024
Penggunaan Gen E6 Sebagai Target Deteksi Human Papillomavirus Tipe 11 dengan Metode Polymerase Chain Reaction

Mariana Wahjudi (2024)

Infeksi Human Papillomavirus (HPV) tipe 11 dapat menyebabkan penyakit condyloma acuminate yang merupakan salah satu faktor risiko terjadinya kanker anogenital. Sampai saat ini, proses deteksi dini HPV kelompok low risk, termasuk untuk tipe 11 did

23-06-2024
Laporan Kasus: Perbaikan Kadar Prolaktin pada Makroadenoma Hipofsis dengan Terapi Bromokriptin dan EETA

Ni Putu A. D. Gayatri (2024)

Hiperprolaktinemia merupakan salah satu gejala klinis yang umum terjadi pada kasus makroadenoma hipofsis. Hiperprolaktinemia yang terjadi pada makroadenoma hipofsis dapat disebabkan oleh adanya penekanan massa tumor terhadap infundibulum (pituita

23-06-2024
Ginekomastia Terkait Efavirenz: Laporan Dua Kasus Pasien HIV

Nurftri Bustamam (2024)

Pada pasien human immunodefciency virus (HIV) positif, terapi antiretroviral (ARV) dapat berkontribusi terhadap kejadian ginekomastia. Ditemukan dua kasus ginekomastia pada pasien HIV di RS Pengayoman Cipinang antara tahun 2017–2019. Pada penel

23-06-2024
Glycemic Control and Its Factor in Type 2 Diabetic Patients in Jakarta

Maiftrianti (2024)

Poor glycemic control is a primary risk factor for the progression of complications. This study aimed to determine the status of glycemic control and associated factors among type 2 Diabetes Mellitus (DM) patients at primary health care of Cakung

23-06-2024
Hubungan Kejadian Infeksi Carbapenem Resistant Acinetobacter baumannii dengan Penggunaan Antibiotika Golongan Karbapenem pada Pasien di Rumah Sakit St. Carolus

Yovita E. Lestari (2024)

Acinetobacter baumannii (Acb) adalah salah satu bakteri gram negatif oportunis yang ada di lingkungan. Karbapenem merupakan salah satu agen antibiotik yang digunakan untuk pengobatan infeksi Acb. Laju resistensi Acb terhadap karbapenem dalam bebe

23-06-2024
Efek Toksik Merkuri dalam Krim Pencerah Wajah dari Perspektif Klinis

Retno Haryanti (2024)

Efek toksik akibat paparan merkuri dapat terjadi melalui berbagai cara, antara lain menghirup uap merkuri, tertelan maupun topikal. Penyerapan merkuri secara topikal dapat terjadi melalui penggunaan produk kosmetik. Salah satu produk kosmetik yan

23-06-2024
Pengetahuan dan Profil Gaya Hidup Sehat pada Orang Dewasa di Pedesaan di Daerah Istimewa Yogyakarta

Aris Widayati (2024)

Kejadian sindrom metabolik (SM) dan penyakit kardiovaskular (PKV) dipengaruhi oleh gaya hidup sehat sehari-hari. Penelitian ini bertujuan mengeksplorasi profil gaya hidup sehat dan pengetahuan tentang hidup sehat dengan pemberian intervensi eduka

23-06-2024
Pemantauan Kadar Obat Indeks Terapi Sempit Melalui Estimasi Kadar Obat di Dalam Darah pada Pasien Rawat Inap di RSUD Prof. Dr. Margono Soekarjo, Purwokerto

Masita W. Suryoputri (2024)

Pemantauan kadar obat dalam darah dapat dilakukan secara matematika dengan pendekatan farmakokinetik. Penelitian ini bertujuan untuk mengetahui estimasi kadar obat indeks terapi sempit di dalam darah sesuai dosis yang diberikan pada pasien rawat

23-06-2024
Effect of Fish Oil, Virgin Coconut Oil, and Used-Cooking Oil Consumption on Mice Hematological Profile

Mas Rizky A. A. Syamsunarno (2024)

Humans require macronutrients and micronutrients to fulfill daily energy requirements, and triglyceride is a notable example, belonging to the fat family. This is particularly consumed frequently, and is composed of glycerol, and the fatty acid,

23-06-2024
Quality of Antibiotic Prescribing for Respiratory Tract Disease in Primary Healthcare Centers in Tegal Regency, Central Java, Indonesia

Farida Fakhrunnisa (2024)

The prescription of antibiotics for diagnosed upper respiratory tract infections (URTIs) is frequently practiced. Furthermore, inappropriate use has been implicated in numerous problems, including the onset of resistance. This study is, therefore

23-06-2024
Hubungan Faktor Okupasi terhadap Aktivitas Asetilkolinesterase Eritrosit dan Fungsi Kognitif pada Petani yang Menggunakan Pestisida Organofosfat

Taufik Hidayatullah (2024)

Organofosfat merupakan pestisida yang disukai oleh petani karena hasilnya terlihat jelas pada tanaman. Namun, pajanan organofosfat terhadap manusia dapat menimbulkan gangguan akut maupun kronis yang disebabkan sifat residunya. Untuk mengetahui pa

23-06-2024
Potensi Vaksin Antibodi Anti-PfRH5 Berbasis Nanopartikel Liposom sebagai Modalitas Preventif Mutakhir pada Plasmodium falciparum Malaria

Agung Bagus S. Satyarsa (2024)

Plasmodium falciparum malaria dalah salah satu penyakit infeksi yang disebabkan oleh parasit protozoa Plasmodium falciparum dengan morbiditas dan mortalitas terbesar kasus malaria pada manusia. Upaya pencegahan dan penanganan Plasmodium falciparu

23-06-2024
Role of Herbal Plants on Autophagy

Susanti Husen (2024)

Autophagy is a biomolecular system known to play an important role in cell growth, development as well as defense mechanisms, and is also a physiological approach towards homeostasis maintenance. This phenomenon is an intermediary pathway in the

23-06-2024
Inovasi Home Care Apoteker melalui Supervisi Penggunaan Obat Geriatri untuk Meningkatkan Kepatuhan Terapi Penyakit Kron

Yuhansyah Nurfauzi (2024)

Abstrak Pelayanan kefarmasian di Indonesia saat ini bergeser mengikuti paradigma patient-oriented. Meningkatnya jumlah pasien lanjut usia (lansia) dengan penyakit kronis membuat apoteker perlu mengembangkan upaya edukatif dan kolaboratif berbasi

23-06-2024
Tata Laksana Terapi Pasien dengan COVID-19: Sebuah Kajian Naratif

Adji P. Setiadi (2024)

Kasus pneumonia yang disebabkan oleh severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) yang disebut coronavirus diseases 2019 (COVID-19) oleh World Health Organization (WHO) merupakan sebuah tragedi dalam dunia kesehatan secara global.

23-06-2024
Masalah-Masalah terkait Pengobatan Diabetes Melitus Tipe 2: Sebuah Studi Kualitatif

Retno Wahyuningrum (2024)

Pengelolaan diabetes melitus tipe 2 (DMT2) yang kompleks memicu masalah-masalah yang menyebabkan sasaran terapi tidak tercapai. Tujuan penelitian ini adalah untuk mengidentifikasi masalah-masalah yang dialami pasien DMT2 dalam pengobatan. Pendeka

23-06-2024
Integrative Pharmacotherapy Teaching with Objective Structured Pharmacotherapy Examination

Abraham Simatupang (2024)

Writing an appropriate prescription is one of the main competencies of medical doctors. Studies reveal that medication error is still a significant issue in health service, and many efforts have been done to minimise this through trainings. Integ

23-06-2024
Role of Autophagy in Preeclampsia

Nurrani M. Dewi (2024)

Autophagy is essential in cell death decisions and can protect cells by preventing them from undergoing apoptosis. Autophagy contributes to a variety of physiological processes, including cell differentiation and various functions in embryogenesi

23-06-2024
Penilaian Risiko Interaksi Obat pada Pasien dengan Diabetes Melitus Tipe 2

Indriastuti Cahyaningsih (2024)

Diabetes melitus tipe 2 merupakan sebuah penyakit yang memiliki risiko menimbulkan komplikasi baik makrovaskular maupun mikrovaskular. Komplikasi yang terjadi menimbulkan jumlah obat yang diresepkan menjadi semakin banyak. Bertambahnya jumlah oba

23-06-2024
Lumbrokinase Reduced the Fibrinogen Concentration in Ischemic Cerebrovascular Disease Patients: A Systematic Review and Meta-Analysis

Yedy P. Sukmawan (2024)

Lumbrokinase has been used to treat stroke and cardiovascular disease. Fibrinogen elevation is a known risk factor and a powerful predictor of ischemic cerebrovascular disease. The objective of this study was to conduct a systematic review and me

23-06-2024
Studi Efektivitas Profilaksis Cefazolin terhadap Pertumbuhan Koloni Bakteri Pascaoperasi: Studi pada Pasien Patah Tulang Panjang Terbuka Grade I dan Grade II di RSUD dr. Saiful Anwar Malang

Thomas E. C. J. Huwae (2024)

Penggunaan antibiotik profilaksis sebelum tindakan bedah telah terbukti dapat mengurangi angka kejadian infeksi setelah operasi. Antibiotik profilaksis dianjurkan hanya untuk tindakan dengan kejadian infeksi yang tinggi dan tindakan dengan konsek

23-06-2024
Induksi Pluripotent Stem Cell dengan Menggunakan Faktor Yamanaka Oct4, Sox2, Klf4, dan c-Myc: Perkembangan dan Tantangan

Irbah Arifa (2024)

Abstrak Sel punca embrionik memiliki kemampuan untuk membelah tanpa batas serta bersifat pluripotensi dan dapat berdiferensiasi menjadi sel dari tiga lapisan kecambah. Percobaan Takahashi dan Yamanaka pada tahun 2006 menunjukkan bahwa induced pl

23-06-2024
Effect of Rhodomyrtus tomentosa Hassk. on HIF1? and VEGF expressions on hypertension placental

Putri Cahaya Situmorang (2024)

Context: HIF1? and VEGF are proteins marker oxidative stress and a decrease in placental growth factor (PlGF). Decreasing of HIF1? and VEGF in rats displayed poor trophoblast differentiation, placental abnormalities, and fetal mortality. Rhodomyrtu

23-06-2024
Design and validation of questionnaires to measure educational needs about medications in students, parents, and teachers in an elementary school

Ana M. Téllez-López (2024)

Context: To achieve a health literacy program aimed at improving the use of medicines, it is necessary to have tools that identify educational needs through valid and reliable instruments. Aims: To validate instruments designed to evaluate the cor

23-06-2024
Serum concentrations of valproic acid in people with epilepsy: Clinical implication

Angel T. Alvarado (2024)

Context: Therapeutic drug monitoring (TDM) allows personalizing the dose of valproic acid in patients with epilepsy to optimize drug therapy, minimize adverse effects and detect interactions. Aims: To determine valproic acid concentrations in seru

23-06-2024
Molecular simulation of compounds from n-hexane fraction of Sonchus arvensis L. leaves as SARS-CoV-2 antiviral through inhibitor activity targeting strategic viral protein

Dwi Kusuma Wahyuni (2024)

Context: COVID-19 was caused by the spread and transmission of SARS-CoV-2 at the end of 2019 until now. The problem comes when antiviral drugs have not yet been found and patients infected with SARS-CoV-2 can trigger a cytokine storm condition due

23-06-2024
Phyllanthus tenellus Roxb. and Kaempferia parviflora Wall. ex Baker compounds as inhibitors of SARS-CoV-2 main protease and RNA-dependent RNA polymerase: A molecular docking study

Suhaina Supian (2024)

Context: The outbreak of a novel coronavirus, SARS-CoV-2 has caused an unprecedented COVID-19 pandemic. To put an end to this pandemic, effective antivirals should be identified or developed for COVID-19 treatment. However, specific and effective a

23-06-2024
Anti-inflammatory effect of caffeic acid phenethyl ester supplementation on TNF-? and NF-?B expressions throughout experimental tooth movement in vivo

Kirana Salikha (2024)

Context: Orthodontic tooth movement (OTM) changes the periodontal tissue and increases the incidence of root resorption (OIRR). Caffeic acid phenethyl ester (CAPE), an antioxidant and anti-inflammatory chemical generated from honey propolis, might

23-06-2024
Potential of polyether ionophore compounds as antimalarials through inhibition on Plasmodium falciparum glutathione S-transferase by molecular docking studies

Alfian Wika Cahyono (2024)

Context: Malaria is still a serious global health problem due to the development of drug resistance. It is necessary to find new drugs with renewable mechanisms that are effective in killing parasites. Our previous research has analyzed more than o

23-06-2024
Antibacterial activity of Stachytarpheta jamaicensis (L.) Vahl roots extract on some bacteria proteins: An in silico and in vitro study

Juliyatin Putri Utami (2024)

Context: Stachytarpheta jamaicensis (L.) Vahl plant is used for traditional therapy because of its content, including flavonoids, alkaloids, tannins, saponins, terpenoids, and coumarins. Aims: To determine the antibacterial ability of S. jamaicens

23-06-2024
In vitro antioxidant properties and antimicrobial activity of the ethanolic extract of Senecio nutans Sch. Beep. (Asteraceae)

Felipe Surco-Laos (2024)

Context: Senecio nutans Sch. Beep. is used by the Andean population of Ayacucho-Peru as traditional medicine for various health problems. Aims: To evaluate the antioxidant and antimicrobial activity of the ethanolic extract of leaves of S. nutans ag

23-06-2024
Virtual prediction of potential immunogenic epitope of candoxin protein from Malayan krait (Bungarus candidus) venom

Rahmat Grahadi (2024)

Context: Malayan krait (Bungarus candidus) is a snake that is considered highly venomous snake and widely distributed across Southeast Asia. Envenomation by this snake is characterized by facial weakness, paralysis, respiratory muscle weakness, and

23-06-2024
Effect of Lissachatina fulica chitosan on the antioxidant and lipid profile of hypercholesterolemic male Wistar rats

Umarudin (2024)

Context: The increase in reactive oxygen species production in hypercholesterolemia can degrade polyunsaturated fatty acids and form malondialdehyde (MDA). There is a need for a natural alternative treatment, such as Lissachatina fulica chitosan.

23-06-2024
Consumo de antibacterianos en tres hospitales de Santiago de Cuba en el período 2019-2020

Maraelys Morales-González (2024)

Context: Infections by multiresistant bacteria increase the risk of therapeutic failure, increasing hospital stay, costs and mortality. This determines the use of more expensive antibacterials with a broader spectrum, which leads to a high consumpt

23-06-2024
Potential of Curcuma xanthorrhiza ethanol extract in inhibiting the growth of T47D breast cancer cell line: In vitro and bioinformatic approach

Nur Fitriana (2024)

Context: Breast cancer most commonly occurs in women globally and has the highest mortality rate in Asia. Therefore, a safe and prominent drug to cure the disease needs to be urgently developed. Aims: To investigate the molecular mechanism of the

23-06-2024
In silico analysis of anti-dengue activity of faloak (Sterculia quadrifida R. Br) stem bark compounds

Audrey G. Riwu (2024)

Context: Dengue is one of the most common infectious diseases found in tropical and subtropical regions, particularly in urban and semi-urban areas. Management dengue until now has not had a specific therapy. The development of dengue therapy using

23-06-2024
Ethnobotanical survey of medicinal plants used to manage hypertension in the Republic of Guinea

Mohamed S. Traore (2024)

Context: Like many other African countries, medicinal plants are widely used in Guinea to manage hypertension, which is a highly prevalent health problem. Aims: To identify the plants used in the traditional management of hypertension in Guinea. Me

23-06-2024
Secang wood (Caesalpinia sappan L.) nanoemulgel activity as antiaging through suppressing the MMP-1 expression and the collagen degradation

Ni Putu Linda Laksmiani (2024)

Context: Aging is closely related to reactive oxygen species (ROS). ROS increases the collagenase enzyme (MMP-1) levels and collagen degradation that causes skin wrinkling. Secang wood (Caesalpinia sappan L.) containing brazilin and brazilein has b

23-06-2024
In vitro and in vivo antimicrobial activity of an active plant-based quadrocomplex for skin hygiene

Viktor A. Filatov (2024)

Context: The current epidemiological situation causes a new surge of interest to perspective antimicrobial formulations for proper skin hygiene. Aims: To evaluate in vitro and in vivo the antimicrobial activity of a novel active quadrocomplex (QC) f

23-06-2024
Wound healing activity of Dillenia ochreata leaves ethanol extract in Wistar rats

Muharni Muharni (2024)

Context: Dillenia ochreata is a medicinal plant used traditionally for scabies treatment. D. ochreata leaves contain secondary metabolites of triterpenoids, phenolics, and steroids that have the potential to accelerate the wound healing process. A

23-06-2024
Effect of cocoa administration during orthodontic tooth movement on RUNX2, calcium levels, and osteoclast bone-resorbing activity in rats

Ananto Ali Alhasyimi (2024)

Context: Cocoa contains caffeine-rich methylxanthine, which promotes accelerated orthodontic tooth movement. Caffeine affects calcium ion equilibrium, causing low bone density and shortening orthodontic treatment. It is unclear how cocoa affects pe

23-06-2024
Development and validation of ultraviolet spectrophotometric methods for lamivudine and zidovudine quantification in dissolution test

Enma Perez-Chauca (2024)

Context: In the development of a good analytical method, the selection of appropriate conditions for quantifying drugs is essential. The method validation should be determined before conducting the dissolution test. Aims: To develop and validate t

23-06-2024
Technology surveillance in veterinary vaccine adjuvants (2015-2022): University-industry interaction

Aníbal Domínguez-Odio (2024)

Context: The new generation of immunoenhancers will have to offer solutions to each clinical and technological limitation that currently exists. This innovative context requires periodic technological surveillance by the veterinary biopharmaceutica

23-06-2024
Validación de la cromatografía líquida de alto rendimiento acoplada a espectrometría de masas para determinar albendazol sulfóxido en plasma humano

Jaime Rosales-Rimache (2024)

Context: Albendazole is used in the treatment of cysticercosis and hydatid disease, and its prolonged administration can generate adverse effects attributed to the active metabolite, albendazole sulfoxide (ABZSO), whose measurement requires validat

23-06-2024
Impact of intervention of community pharmacists on cardiovascular outcomes in Spain: A systematic review

Marjan Manouchehri (2024)

Context: Cardiovascular disease (CVD) is one of the leading causes of morbidity and premature mortality across Spain. According to the World Health Organization (WHO), 80% of these premature deaths are preventable by controlling cardiovascular risk

23-06-2024
Activation of microvesicle peripheral blood mononuclear cells by mesenchymal stem cells secretome co-cultivated with osteosarcoma stem cell

Fachrizal Arfani Prawiragara (2024)

Context: Microvesicle is a cell micro molecule that may play a role in the process of osteosarcoma stem cell apoptosis. Aims: To investigate the activity of peripheral blood mononuclear cells (PBMCs) through the secretion of interleukin-2 (IL-2), in

23-06-2024
E-cigarette smoking: Awareness, use, and perceptions of Vietnamese personnel

Thoai Dang Nguyen (2024)

Context: Electronic cigarettes (e-cigarettes) are considerably popular, particularly among young adults. Their effects have elicited strong interest in cigarette control and community health, but evidence on the knowledge, usage, and perceptions of

23-06-2024
Willingness to participate in clinical trials: A cross-sectional analysis in Ho Chi Minh City, Vietnam

Thoai N. Dang (2024)

Context: Clinical trial is an experiment on comparable groups of human beings which evaluates the efficacy of a treatment or medical intervention by comparing the effects with other testing treatments or control treatments. Clinical trials help dev

23-06-2024
Acute oral toxicological evaluation in Wistar rats of interruptin-rich extract from Cyclosorus terminans and its in vitro antidiabetic potential

Sujinda Songtrai (2024)

Context: Interruptins A and B derivatives from edible fern Cyclosorus terminans have been reported properties including anti-bacterial, anti-cancer, antioxidation, anti-inflammatory, and antidiabetic activities. Unfortunately, studies on its safety a

23-06-2024
Moringa oleifera extract regulates the expression of some sickle cell related genes in normal Wistar rats

Mojisola C. Cyril-Olutayo (2024)

Context: In the current study, we employed gene-regulatory based approach to underscore the putative mechanism of how components of Moringa oleifera (MO) ethanol extract exert its antisickling effects. Aims: To evaluate the relationship between mR

23-06-2024
Plantas medicinales con potencial actividad neuroprotectora estudiadas en cepas transgénicas de Caenorhabditis elegans. Revisión sistemática 2010-2021

Yenny Y. Lozano (2024)

Context: Treatments for neurodegenerative diseases generate multiple adverse effects and do not reverse the progressive damage of the disease. It is a priority to find alternatives from medicinal plants as a source of molecules with neuroprotective

23-06-2024
Anti-inflammatory and antioxidant potential of Syzygium polyanthum (Wight) Walp. bioactive compounds in polycystic ovary syndrome: An in silico study

Renny Aditya (2024)

Context: Polycystic ovary syndrome (PCOS) is significantly associated with inflammation and oxidative stress. Syzygium polyanthum is a plant rich in pharmacological properties. Aims: To evaluate the anti-inflammation and antioxidant potential of S.

23-06-2024
Willingness to volunteer in future HIV vaccine clinical trials: A literature review and evidence synthesis

Tram N.T. Huyen (2024)

Context: Developing an effective vaccine for HIV/AIDS is a global endeavor requiring the participation of willing volunteers. Aims: To evaluate the willingness of the global population to undergo vaccination and participate in clinical trials. Meth

23-06-2024
Acceptability of and willingness to pay for human immunodeficiency virus vaccination: A systematic literature review

Tram N.T. Huyen (2024)

Context: Vaccines for the human immunodeficiency virus (HIV) have considerably improved public health in the last century. Important considerations, however, are that effective vaccination substantially depends on the acceptability of future vaccin

23-06-2024
Pectinas modificadas con actividad contra el cáncer de colon: Una revisión sistemática de 2010-2021

Matías Pérez-Loyola (2024)

Context: Colon cancer is a serious disease that can be hereditary or arise from exposure to carcinogens in unhealthy food. Current chemotherapy treatment has serious cardiovascular adverse effects, is not always effective, and there may be resistan

23-06-2024
Usefulness of American College of Cardiology/American Heart Association treatment-resistant hypertension criteria among end-stage kidney disease patients – A case series

Shorouq Khader Abujadallah (2024)

Context: American College of Cardiology/American Heart Association (ACC/AHA) antihypertensive treatment-resistance criteria have been not used in the hemodialysis (HD) population. Aims: To assess interim Blood Pressure (BP) measures in End-Stage K

23-06-2024
The effect of Aloe vera on fasting blood glucose levels in pre-diabetes and type 2 diabetes mellitus: A systematic review and meta-analysis

Indah Budiastutik (2024)

Context: : Aloe vera is a traditional medicinal plant that shows a wide range of biological activities. Previous studies demonstrated the antihyperglycemic effect of Aloe vera but with inconsistent results. Aims: To quantitatively summarize the ef

23-06-2024
Application of hydroxypropylated crosslinked starch from the grains of Oryza sativa L. as potential disintegrant in compressed solid dosage form

Elizabeth A. Pagtalunan (2024)

Context: The modification of starch from the grains of NSICRc222 rice variety may provide a new material with enhanced disintegrating functionality in compressed solid dosage forms. Aims: To synthesize hydroxypropylated crosslinked rice starch tha

23-06-2024
Flavonoids as potential inhibitors of dengue virus 2 (DENV2) envelope protein

Rachel Raditya Renantha (2024)

Context: Dengue viruses (DENVs) are the cause of dengue disease, which is one of the most frequent diseases caused by mosquito-borne viral infections. Currently, no specific treatment is available for dengue. Aims: To identify the most promising i

23-06-2024
Computational study of Cu2+, Fe2+, Mn2+, Mn3+, Fe3+, CrO4 2- , Si4+ , and Hg+ binding sites identification on cytokines to predict dental metal allergy: An in silico study

Titiek Berniyanti (2024)

Context: Metal allergy is a general term to describe allergic diseases due to the release of metal ion reactions in the body which are mediated by T cells and involve inflammatory cytokines that can cause morbidity and mortality. Molecular docking

23-06-2024
Molecular docking of polyether ether ketone and nano-hydroxyapatite as biomaterial candidates for orthodontic mini-implant fabricatio

I Gusti Aju Wahju Ardani (2024)

Context: Modified polyether ether ketone (PEEK) by adding nano-hydroxyapatite (HA) material on its fixture for mini-implant fabrication may increase resistance force through osseointegration. Aims: To analyze the binding molecular docking of PEEK

23-06-2024
Histological analyses of orthodontic force in Cavia porcellus: Comparison between immunohistochemistry and hematoxylin-eosin

Erliera Sufarnap (2024)

Context: Histological quantification of osteoclasts and osteoblasts can evaluate biological responses to orthodontic tooth movement. Histological analysis of bone samples can be technically challenging. Aims: To evaluate the differences between he

23-06-2024
Lysozyme quantity and quality in relation with early childhood caries: A longitudinal study

Essie Octiara (2024)

Context: Several studies have reported the relationship between lysozyme quantity (concentration) and quality (activity) with early childhood caries (ECC), but the results remain controversial. These are controversial, probably due to the cross-sect

23-06-2024
In silico ADME-T and molecular docking study of phytoconstituents from Tithonia diversifolia (Hemsl.) A. Gray on various targets of diabetic nephropathy

Oktavia Rahayu Adianingsih (2024)

Context: Tithonia diversifolia (Hemsl.) A. Gray has been known for treatment of diabetes mellitus, yet its mechanism as anti-diabetic has not been defined. There are various therapeutic targets for diabetes and its complication such as diabetic nep

23-06-2024
Phytochemical characterization and mushroom tyrosinase inhibition of different extracts from Salvia officinalis L. leaves

Lana Y.M. Juee (2024)

Context: Sage (Salvia officinalis) is an ancient valuable plant used in the treatment of variant health issues. Aims: To evaluate the depigmentation activity of S. officinalis leaf chloroformic (SOCF) and ethanolic (SOMF) extracts via its efficacy t

23-06-2024
Effect of 1,4-naphthoquinone from Sisyrinchium palmifolium L. extract on in vivo Ki-67 expression and in silico CDK1, CDK2, CDK4 on colitis-associated colon cancer

Roihatul Muti’ah (2024)

Context: Medicinal plants can be used as an option for the prevention and reduction of cancer cell resistance and its side effects. Sisyrinchium palmifolium L. is thought to have anti-cancer activity with a compound content of 1,4-naphthoquinone. A

23-06-2024
Chemical composition, in vitro assessment of antioxidant properties and cytotoxicity activity of ethanolic and aqueous extracts of Ajuga orientalis L. (Lamiaceae)

Sawsan A. Oran (2024)

Context: Ajuga orientalis L. (Lamiaceae) is an aromatic herb used in traditional medicine in Jordan and neighboring countries. Aims: To evaluate the cytotoxic potential of ethanolic and aqueous extracts from the aerial parts of A. orientalis against

23-06-2024
Phytochemical composition and antioxidant capacity of the aqueous extracts of Malva sylvestris L. and Malva pseudolavatera Webb & Berthel.

Glenda M. Sarmiento Tomala (2024)

Context: Malva spp. have been widely used in the world as traditional remedies. In Ecuadorian markers Malva sylvestris and Malva pseudolavatera are the species most commercialized. However, the scientific information about M. pseudolavatera is litt

23-06-2024
Antimicrobial prescriptions in cancer patients: An evaluation based on clinical and pharmacotherapeutic indicators

Dorgerys García Falcón (2024)

Context: The inappropriate use of antimicrobials is a public worldwide health problem that causes increased morbidity and mortality, bacterial resistance, and care costs and hospitalizations. Aims: To evaluate the prescription of antimicrobials in

23-06-2024
Antiulcer effect of Helminthostachys zeylanica (L.) Hook. root extract on ethanol-induced acute gastric lesion in Wistar rats

Fitrya (2024)

Context: Helminthostachys zeylanica is well known as a traditional medicine with various pharmacological activities, including antioxidant and antiinflammatory. These activities are needed in the treatment of gastric ulcers. Aims: To evaluate the ef

23-06-2024
Aromatic and medicinal plants in the Ifrane region (Morocco): Floristic diversity, with special emphasis on ethnobotanical and socioeconomic studies of six spontaneous plants

Fatima Zahrae Radi (2024)

Context: As part of a huge project to assess Aromatic and Medicinal Plants (AMP) in the Ifrane-region, we made a list of these AMP through a floristic study, then we carried out ethnobotanical and socio-economic studies of six AMP belonging to thre

23-06-2024
Volatile compounds from Phyla scaberrima (Juss. ex Pers.) Moldenke and Dysphania ambrosioides (L.) Mosyakin & Clemants as possible SARS-CoV-2 protease inhibitors: Identification and in-silico study

Neyder Contreras-Puentes (2024)

Context: COVID-19 is a pandemic that has affected the entire population, characterized by multisystemic involvement. With around 130 million cases of infection and more than 2.5 million deaths globally. However, the development of a low-efficacy tr

23-06-2024
Antidiabetic potential of leaf extracts of Ecobolium linneanum Kurz in streptozotocin-induced diabetic rats

Srilakshmi Nallapaty (2024)

Context: In a general context, the importance’s of several medicinal plants has been explored in treating diabetes mellitus. In this connection, the antidiabetic potentiality needs to be established for one of the medicinally emerging plants Ecbo

23-06-2024
Effects of swimming exercise and RLN2 induction on relaxin levels, MMP-13, TGF? expression in the pubic cartilage of pregnant rats

Ika Oktaviani (2024)

Context: Swimming exercises can be used as an intervention to maintain the stability of the synthesis of the pubic symphysis cartilage. Aims: To evaluate the effects of swimming exercise on relaxin levels, MMP-13, TGF? expression in pubic cartilage

23-06-2024
Anthocyanin, tartaric acid, ascorbic acid of roselle flower (Hibiscus sabdariffa L.) for immunomodulatory adjuvant therapy in oral manifestation coronavirus disease-19: An immunoinformatic approach

Nastiti Faradilla Ramadhani (2024)

Context: Oral manifestations that arose from COVID-19 infection often causes morbidity and systemic drug administration is less effective. Roselle flower (Hibiscus sabdariffa) is one of the plants that is often used in infusion as it gives health b

23-06-2024
The ovulation assessment of regular cyclic rats following subacute oral administration of monosodium glutamate: An in vivo study

Mahfoudh Almusli Mohammed Abdulghani (2024)

Context: The possible toxic effects of monosodium glutamate (MSG) on ovarian functions have not been thoroughly evaluated in contrast to testicular functions. Few studies documented that MSG showed histological alterations. Aims: To investigate th

23-06-2024
Estudio farmacognóstico y capacidad antioxidante de la especie Smilax purhampuy Ruiz que crece en Ecuador

Pilar A. Soledispa Cañarte (2024)

Context: Smilax purhampuy Ruiz (sarsaparilla) is traditionally used to treat various ailments such as sudorific, diuretic, purifying, hypoglycemic, arthritis, dermatological infections, intestinal, stomach and prostate inflammations, vaginitis and

23-06-2024
Pharmacological studies of anti-inflammatory, anti-nociceptive and anti-pyretic compounds found in chromatographic fractions of Anogeissus leiocarpa (DC). Guill. & Perr. leaves

Precious A. Idakwoji (2024)

Context: The anti-nociceptive and anti-pyretic properties of the crude aqueous extract of Anogeissus leiocarpa (DC). Guill. & Perr. leaves have been reported. Aims: To investigate the anti-inflammatory, anti-nociceptive, and anti-pyretic properties

23-06-2024
Molecular characterization and prediction of B-cell epitopes for the development of SARS-CoV-2 vaccine through bioinformatics approach

Aamir Shehzad (2024)

Context: The SARS-CoV-2 virus is the cause of the COVID-19 pandemic, which is a severe public health crisis worldwide. Aims: To analyze the SARS-CoV-2 isolates of Surabaya and predict ORF1ab polyprotein epitopes through the bioinformatics approach f

23-06-2024
Phytotherapy in response to COVID-19 and risks of intoxication: A field study in the city of Meknes (Morocco)

Mariame Najem (2024)

Context: The contagious global pandemic of coronavirus 2019 (COVID-19) has prompted many Moroccans to turn to traditional phytoremedies. Aims: To highlight the ethnopharmacological information and the risks of intoxication related to the use of herb

23-06-2024
Development of a multi-epitope spike glycoprotein vaccine to combat SARS-CoV-2 using the bioinformatics approach

Aamir Shehzad (2024)

Context: The current COVID-19 pandemic has significantly impacted health and socio-economic status worldwide. The only way to combat this situation is to develop an effective vaccine and immunize people around the globe. Aims: To construct a multi

23-06-2024
Suitability in compounding sterile preparations: An observational study in a referral hospital

Erza Genatrika (2024)

Context: Compounding sterile preparations in hospitals requires special attention because the process is more complex. Errors that occur when compounding sterile preparations can cause contamination of the prepared preparations. Aims: To evaluate

23-06-2024
Validation of a UV spectrophotometric method to quantify losartan potassium in tablets from the dissolution test at pH 1.2, 4.5 and 6.8

Antonella S. Araujo-Fernandez (2024)

Context: The validation of a method is synonymous with the quality of the obtained results. The dissolution test is an analytical technique to evaluate the quality and stability of drugs during their development. Aims: To evaluate whether the UV s

23-06-2024
Effect of Nigella sativa L. extract on improving memory function through reducing GSK3? activation and A?42/40 ratio

Kusuma Andriana (2024)

Context: Alzheimer's disease (AD) is one of the biggest causes of public health problems today, especially in older, where women have a greater risk of developing AD than men. However, the current AD therapy has not been satisfactory. Nigella sativ

23-06-2024
Effect of Vitis gracilis Wall (gagatan harimau) in the recovery of gastrocnemius muscle cells and cytochrome c expression of Mus musculus

Nila Zusmita Wasnis (2024)

Context: Physical exercise with maximum intensity to fatigue can cause impaired immunity. Gastrocnemius muscle damage is found in eccentric activities in sports. Vitis gracilis has been proven as a healing agent for degenerative diseases. Aims: To

23-06-2024
Effect of sikkam (Bischofia javanica Blume) ethanolic extract on the quality and quantity of hyperglycemic rat sperm

Syafruddin Ilyas (2024)

Context: Hyperglycemia causes diabetes mellitus (DM), abnormal metabolism, oxidative stress, and chronic complications such as impotence. Hyperglycemia causes testicular atrophy and stromal cell, seminiferous tubular damage, and spermatogenic cells

23-06-2024
Studies on antidiabetic herbal formulations available in the herbal stores of Karachi, Pakistan

Erum Shah (2024)

Context: Diabetes mellitus is a condition, which is characterized by persistent hyperglycemia, abnormal functioning of insulin and difficulty in the metabolism of carbohydrates, fats and proteins. Antidiabetic medicines of herbal origin are widely

23-06-2024
Visualization of mucosa by gastroscopy evaluation using pre-preparation procedure with simethicone

Silvia P. Ortega-Moya (2024)

Context: A solution of simethicone administrated orally before the scan endoscopy procedure is recommended as a good means to reduce the bubbles interference. Aims: To evaluate the reliability, reproducibility and effectiveness of simethicone pre-t

23-06-2024
Molecular docking study of the main phytochemicals of some medicinal plants used against COVID-19 by the rural population of Al-Haouz region, Morocco

Ridwane Ghanimi (2024)

Context: The infection by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a global health emergency. The management of this crisis requires the discovery of new drugs able to cure or reduce the severity of SARS-CoV-2. Aims: To expl

23-06-2024
Ethnobotanical and ethnopharmacological study of medicinal plants used in the treatment of anemia in the region of Haouz-Rehamna (Morocco)

Ouafae Benkhnigue (2024)

Context: The ethnobotanical study of the plants used is of great interest in the medical field. In this perspective, we have carried out this ethnobotanical and ethnopharmacological study, which is part of the development of plant resources traditi

23-06-2024
Evaluating the impact of COVID-19 on mental health of the public in Jordan: A cross-sectional study

Yara A. Suleiman (2024)

Context: Although the COVID-19 pandemic was expected to have a significant impact on the mental health of the Jordanian population, there have been few studies to investigate the nature and magnitude of the impact. Aims: To assess the potential ps

23-06-2024
Macroscopical and microscopical analysis of selected Indian medicinal plants and HPTLC method for quantification of chemical markers in a polyherbal formulation

Karunanithi Shalini (2024)

Context: Pharmacognostical standardization of crude drugs is essential before carrying out its scientific validation as it furnishes the identity and authenticity of the plant. The present work was undertaken to establish the macroscopic, microscop

23-06-2024
Computational study of Curcuma zanthorrhiza Roxb compounds as potential antidiabetic towards alpha-amylase, alpha-glucosidase, and Keap1 inhibition

Sasangka Prasetyawan (2024)

Context: Curcuma zanthorrhiza Roxb is traditionally used as a medicinal herb that is believed might cure some diseases. However, there is still a lack of information about the underlying mechanism of bioactive compounds from C. zanthorrhiza, which

23-06-2024
Mangifera indica L. extract tablets supplementation in patients with knee osteoarthritis pain. A controlled pilot study

Bárbara B. Garrido-Suárez (2024)

Context: Several experimental results and clinical reports using Mangifera indica L extract (MSBE) suggest its potential utility in osteoarthritis (OA) mixed pain. Aims: To examine the possible therapeutic effects and safety of supplementation on os

23-06-2024
Reacciones adversas por antibióticos y anti-inflamatorios no esteroideos en pacientes ambulatorios en Honduras

Karen Orellana (2024)

Context: Adverse drug reactions represent one of the leading causes of hospitalization and death. Aims: To characterize adverse reactions due to antibiotics and nonsteroidal anti-inflammatory drugs in outpatients over 18 years of age. Methods: Cros

23-06-2024
Automedicación en pacientes mayores de 18 años en centros de salud de Honduras

Alejandro Carias (2024)

Context: Inappropriate self-medication is seen as a global public health concern. Without appropriate professional healthcare guidance, a variety of issues can arise with potentially serious consequences to one’s personal health. Aims: To descri

23-06-2024
Systematic review of the safety and efficacy of antazoline in the treatment of atrial fibrillation

Raghad Aldulaymi (2024)

Context: In the emergency department, patients with recent-onset atrial fibrillation are typically managed with intravenous antiarrhythmic agents. However, the currently used agents have a low efficacy and safety profile. Antazoline is an antihista

23-06-2024
Induction of apoptosis by Ruta chalepensis L. essential oil in human breast cancer cells (MCF-7)

Arwa R. Althaher (2024)

Context: Recent scientific studies have reported that essential oils induce apoptosis in various cancer cell types by interfering with intracellular signaling pathways. Aims: To evaluate the cytotoxicity, the apoptotic activity of essential oil (E

23-06-2024
Efficacy of fractional flow reserve measurement in the assessment of stenotic lesions of coronary artery

Anh Binh Ho (2024)

Context: The decision to perform an intervention on a narrowed coronary artery depends on the ischemia caused by the stenosis. The indication for intervention usually applies to cases with ?70% stenosis of vascular diameter because of the risk of m

23-06-2024
Herbal combination from Moringa oleifera Lam. and Curcuma longa L. as SARS-CoV-2 antiviral via dual inhibitor pathway: A viroinformatics approach

Viol Dhea Kharisma (2024)

Context: The COVID-19 outbreak is caused by the transmission and infection of SARS-CoV-2 at the end of 2019. It has led many countries to implement lockdown policies to prevent the viral spreading. Problems arise in a COVID-19 patient because of vi

23-06-2024
Essential oils from Elettaria cardamomum (L.) Maton grains and Cinnamomum verum J. Presl barks: Chemical examination and bioactivity studies

Wael A. Al-Zereini (2024)

Context: Elettaria cardamomum (L.) Maton grains and Cinnamomum verum J. Presl barks are immensely consumed by Jordanian population as food flavoring and remedies in treating different disorders without awareness of their effect or dose toxicity. A

23-06-2024
Anticancer activity of Piper cubeba L. extract on triple negative breast cancer MDA-MB-231

Saowanee Maungchanburi (2024)

Context: Piper cubeba L. (family Piperaceae) is used traditionally for the treatment of many diseases, including cancer. Aims: To determine the anticancer activity of P. cubeba crude extracts on cancer cells and identify chemical constituents of the

23-06-2024
Pharmacognostical standardisation of an epiphytic orchid, Luisia tenuifolia Blume

Sakthi P. Sethuraman (2024)

Context: Pharmacognostical standardization of crude drugs is essential before carrying out its scientific validation as it furnishes the identity and authenticity of the plant. Luisia tenuifolia Blume also known as ‘slender leaved Luisia’, has

23-06-2024
The use of insulin in treatment for inpatients with diabetes in Can Tho, Vietnam 2017 to 2020

Duyen Thi My Huynh (2024)

Context: Diabetes is a dangerous chronic disease with a rapidly increasing rate of hospitalization and death. Patients with uncontrolled diabetes are prone to dangerous acute and chronic complications. Aims: To determine the characteristics of ins

23-06-2024
Antibiotic prescribing errors generated by the use of an electronic prescribing system in the emergency department: A mixed-method study

Ahmad Z. Al Meslamani (2024)

Context: Inappropriate prescribing of antibiotics can result in serious patient harm. Aims: To investigate the incidence, nature, clinical severity, and causes of antibiotic prescribing errors (APEs) in the emergency department (ED) of a large hos

23-06-2024
Zanthoxylum rhetsa (Roxb.) DC: A systematic review on traditional uses, phytochemistry, and pharmacology

Farina Aziz (2024)

Context: Zanthoxylum rhetsa (Roxb.) DC is a plant rich in essential oils, terpenes, coumarins, and alkaloids, among others, and has traditionally been used by tribal healers for decades. But as yet, there is no systematic and critical review on thi

23-06-2024
Ammodaucus leucotrichus Coss. & Durieu: Antihyperglycemic activity via the inhibition of ?-amylase, ?-glucosidase, and intestinal glucose absorption activities and its chemical composition

Saliha Bouknana (2024)

Context: Ammodaucus leucotrichus commonly known as a ‘Kamune es sufi or akâman’ in Morocco, is used to treat many diseases including diabetes. Aims: To investigate the antihyperglycemic activity of an aqueous extract of fruits A. leucotrichus (

23-06-2024
Systematic review of flaxseed (Linum usitatissimum L.) extract and formulation in wound healing

Abdul Talib Mat Sharil (2024)

Context: Flaxseed constituents provide to antioxidant, anti-inflammatory, antimicrobial and wound healing benefits. Aims: To systematically review the experimental evidence on the wound healing ability of flaxseed extracts and formulations. Methods

23-06-2024
Impact of extraction mode on phytoconstituents and antidiabetic activity of extracts of Calotropis procera (Aiton) Dryand

Sadaf Iftikhar (2024)

Context: The extraction mode plays a key role in extracting a particular type of pharmacologically active compounds that can be isolated as leads to develop novel therapeutic molecules. Aims: To evaluate the impact of extraction mode on extract yi

23-06-2024
Ethnobotanical study of plants used for medicinal, cosmetic, and food purposes in the region of Moulay Yacoub, Northeast of Morocco

Mostafa El Khomsi (2024)

Context: Medicinal and aromatic plants are used by people for various purposes, whether for health care, beauty, or as a food source. Aims: To valorize the knowledge about their uses, therapeutic, cosmetic, and food. Methods: The ethnobotanical stu

23-06-2024
Pharmacognostical, physicochemical and phytochemical evaluation of Huberantha senjiana (Annonaceae) leaf: An endemic tree of Gingee Hills Tamil Nadu India

Rajakannu Pandiyan (2024)

Context: Huberantha senjiana (Annonaceae) is a small tree found in dry rocky soils. It is an endemic species native to the Gingee hills of the Villupuram district of Tamil Nadu, India. The literature survey provides no scientific evidence on its ph

23-06-2024
In vivo bronchodilator evaluation of the ethanolic extract of the stems of Jatropha macrantha Müll.Arg.

Haydee Chávez (2024)

Context: Asthma is characterized by hyperresponsiveness and bronchoconstriction, induced by histamine and other noxes, with a prevalence in Peru of 20.7-28.2%, which is why, in traditional medicine, Jatropha macrantha Müll.Arg is used. Aims:

23-06-2024
Phenolic fraction concentrate of Phoenix dactylifera L. seeds: A promising antioxidant and glucose regulator

Samir Bikri (2024)

Context: The beneficial effects of natural polyphenolic compounds are increasingly emerging as powerful antioxidants and digestive boosters. Phoenix dactylifera seeds are recently identified as a healthy functional food with rich amounts of phen

23-06-2024
The potential of liquid smoke as an oral ulcer remedies: A proposed mechanism based on systematic review

Meircurius D.C. Surboyo (2024)

Context: The standard management of oral ulcer therapy is focused only on symptomatic therapy, such as reducing pain. To date, there is no topical drug that has the pharmacodynamics to intervene in oral ulcer pathogenicity. Liquid smoke is trad

23-06-2024
Antioxidant activity, xanthine oxidase inhibition and acute oral toxicity of Dillenia philippinensis Rolfe (Dilleniaceae) leaf extract

Sarah S. Ansari (2024)

Context: Hyperuricemia is a metabolic syndrome characterized by a high serum uric acid level with an increased risk of gout, diabetes, cardiovascular and renal disease. Allopurinol is a widely known xanthine oxidase inhibitor that lowers serum

23-06-2024
In vitro assessment of antioxidant, anti-inflammatory, neuroprotective and antimicrobial activities of Centaurea tougourensis Boiss. & Reut

Mohamed Sabri Bensaad (2024)

Context: More than 500 Centaurea species compose the Asteraceae family, and most of the recent studies made on the species of this genus proved their pharmacological potential, especially to treat chronic illnesses. Aims: To evaluate for the firs

23-06-2024
Viroinformatics investigation of B-cell epitope conserved region in SARS-CoV-2 lineage B.1.1.7 isolates originated from Indonesia to develop vaccine candidate against COVID-19

Arif N. M. Ansori (2024)

Context: SARS-CoV-2, a member of family Coronaviridae and the causative agent of COVID-19, is a virus which is transmitted to human and other mammals. Aims: To analyze the B-cell epitope conserved region and viroinformatics-based study of the

23-06-2024
Benchmarking clinical pharmacy services in the United Arab Emirates with United States of America and Sweden

Rand Haider Al Zahawi (2024)

Context: Clinical Pharmacy services in the United Arab Emirates (UAE) are evolving, mostly with reference to the advancements in the United States of America (USA). American and Swedish healthcare agencies are operating healthcare facilities in

23-06-2024
Time-kill kinetics and mechanism of action of Caesalpinia sappan L. and Ochna integerrima (Lour.) Merr. water extracts against pathogenic bacteria

Prapairat Seephonkai (2024)

Context: Caesalpinia sappan and Ochna integerrima are two native plants of Thailand and distributed widely throughout the country. Recently, water extracts from the stem bark of C. sappan and O. integerrima were found to exhibit potently antiba

23-06-2024
Osteoclast activity in osteoporosis mandibular bone based on RANKL and osteoprotegerin ratio

Mefina Kuntjoro (2024)

Context: Osteoporosis occurs not only in the lumbar bone, femur, and radius but also occurs in the mandibular bone. Therefore, osteoporosis is a disease that required attention from the dentists. Aims: To determine the ratio of Receptor Activato

23-06-2024
Cytoprotective activity of extracts from Adelia ricinella L. aerial parts

Clara A. Berenguer-Rivas (2024)

Context: Several factors can affect the erythrocyte cell membrane integrity targeting important hematological alterations that can be avoided by the cytoprotective effect offered by some plant extracts. Aims: To evaluate the cytoprotective activ

23-06-2024
Anti-breast cancer potential activity of Phaleria macrocarpa (Scheff.) Boerl. leaf extract through in silico studies

Yuyun Ika Christina (2024)

Context: The development of apoptotic agent from natural plant products may have a beneficial effect as a promising candidate for cancer therapy. The study about the efficacy of Phaleria macrocarpa leaves on breast cancer is still limited. Aims

23-06-2024
The real impact of COVID-19 on community pharmacy professionals as part of the primary health care frontier workforce in Spain

Marjan Manouchehri (2024)

Context: Spain was at the epicenter of the pandemic. Health centers across Spanish territory were not able to respond to non-emergency enquiries, leaving community pharmacies as the first point of patient’s contact. Aims: To investigate the i

23-06-2024
Antibacterial, antioxidant and neuroprotective activities of crude extract from the endophytic fungus Fusarium sp. isolate OQ-Fus-2-F from Euphorbia sp. plant

Omar S. Al-Qaralleh (2024)

Context: Human life is contested with the emergence of new infectious diseases and antibiotic-resistant pathogens, cellular deterioration due to oxidative stress, and age-related neurodegenerative disorders. Aims: To evaluate the antibacterial,

23-06-2024
Rapid qualitative and quantitative HPLC/MS analysis of an antioxidant couple consisted of glutathione and ascorbic acid in a pharmaceutical product

Stanislav V. Yefimov (2024)

Context: In pharmacy products, glutathione and vitamin C are often present together. Both components not only enhance each other's action but also protect each other from oxidation, forming an antioxidant couple. The work is devoted to the devel

23-06-2024
A proposed model of user satisfaction with medical emergency services by using the SERVQUAL model

Jonathan Bermúdez-Hernández (2024)

Context: Health care quality has been widely discussed for over 40 years. However, it is still complex to define, understand, and assess it due to the multiple factors it involves, especially in the emergency services. Aims: To identify the main

23-06-2024
Natural products repurposing of the H5N1-based lead compounds for the most fit inhibitors against 3C-like protease of SARS-CoV-2

Arli Aditya Parikesit (2024)

Context: COVID-19 pandemic has caused more than 2.7 million mortality worldwide. Although the COVID-19 vaccine has been developed, the amount is still limited, and very few countries have reached ‘herd immunity’ level. In this regard, impor

23-06-2024
A bioinformatic approach of hydroxyapatite and polymethylmethacrylate composite exploration as dental implant biomaterial

Chiquita Prahasanti (2024)

Context: The most common biomaterial used for dental implants is titanium. However, the release of metal ions and the risk of allergic reactions to metals that may occur in some patients cannot be avoided. Hydroxyapatite-polymethylmethacrylate

23-06-2024
The effect of early switching from intravenous to oral antibiotic therapy: a randomized controlled trial

Anh Dung Nguyen (2024)

Context: The benefit of early switching from intravenous (IV) to oral (PO) antibiotic therapy has been controversial during the last few decades. Aims: To evaluate the effect of early switching from IV to PO antibiotics on treatment outcomes in

23-06-2024
Validating and developing TLC-based fingerprinting for Curcuma longa L.

Kartini Kartini (2024)

Context: Curcuma longa (turmeric) is extensively cultivated as spices and herbal medicines in tropical and sub-tropical countries. Geographical origin is known to significantly determine the quality of the herbs used and, consequently, the safe

23-06-2024
Antidiarrheal activity of aqueous extract of leaves of Euphorbia hirta L

Rushabh S. Shah (2024)

Context: Euphorbia hirta L. is widely distributed in the Indian subcontinent and has many ethnomedicinal uses. Traditionally, the leaves of E. hirta have been used as antidiarrheal agents, for bronchial and respiratory diseases and against conj

23-06-2024
Antispasmodic activity of Warionia saharae Benthem ex Benth. & Coss. on the rabbit and rat jejunums

Ouafa Amrani (2024)

Context: Warionia saharae Benthem ex Benth. & Coss has been widely used for gastrointestinal problems in Morocco and Algeria. Aims: To explore the possible mechanism for its use to such ailments in order to rationalize some of these folkloric us

23-06-2024
Development, characterization in vitro and in silico of coenzyme Q10 loaded myristic acid with different liquid lipids nanostructured lipid carriers

Ni Luh Dewi Aryani (2024)

Context: Nanostructured lipid carriers can enhance skin penetration of active substances. Coenzyme Q10 is a lipophilic antioxidant, that has poor skin penetration. This limitation is overcome by nanostructured lipid carriers. Aims: To develope

23-06-2024
Profile and management of pediatric brain tumors: A single–center experience

Nhu Hiep Pham (2024)

Context: Pediatric brain tumors are the most common solid tumors and the leading cause of death among children worldwide. Although there are some published studies from many countries regarding the pathological model of pediatric brain tumors,

23-06-2024
The ?-mangostin effect on the quantity of TGF-?1 titer relate to the mandibular bone volume of Rattus novergicus in the periodontitis model

Citra Lestari (2024)

Context: Periodontitis causes pocket formation, gingival recession, and destruction of periodontal ligaments and alveolar bone. Periodontitis disturbs the attachment of periodontal ligaments to the maxillary and mandibular bones. The ?-mangosti

23-06-2024
Ethnobotanical and toxicology study of medicinal plants used for the treatment of diabetes in the High Atlas Central of Morocco

Souad Belhaj (2024)

Context: Diabetes mellitus is considered one of the scourges of the third millennium in the world for several years. Aims: To evaluate, identify and preserve the experiences gained over the centuries. It is about therapeutic use of medicinal pla

23-06-2024
Ethnopharmacological study of flavonoid compounds in Magnolia champaca (L.) Baill. ex Pierre as anti-inflammatory agents by molecular docking

Khoirin Maghfiroh (2024)

Context: Magnolia champaca (L.) Baill. ex Pierre has traditionally been used by the culture to prevent and cure the inflammatory disease. Aims: To determine the benefit of M. champaca in the local community, especially in the treatment of tuberc

23-06-2024
Gallic acid protects against cadmium chloride-induced alterations in Wistar rats via the antioxidant defense mechanism

Oluwafemi Adeleke Ojo (2024)

Context: Cadmium has been considered as one of the most hazardous toxic compounds with harmfully effect on the health of organisms. Aims: To evaluate the effects of gallic acid (GA) on the cadmiuminduced liver and renal oxidative stress in Wistar r

23-06-2024
Insulin expression and insulitis degree of diabetic rats after giving sikkam leaves (Bischofia javanica Blume)

Cheryl GP. Rumahorbo (2024)

Context: Gallic acid and quercetin in sikkam leaves (Bischofia javanica) have scientific potential as antidiabetic agents. Quercetin suppresses hyperglycemia by inhibiting active glucose transport. Meanwhile, gallic acid acts as an antidiabetic

23-06-2024
Ethnobotanical and agronomical survey of Brocchia cinerea (Delile) Vis. plant used by people in the Figuig and Draa-Tafilalet regions, Morocco

Nisrine Chlif (2024)

Context: As part of the development of the natural heritage of Morocco, an ethnobotanical and agronomic study was conducted in the regions of Figuig and Draa- Tafilalet. Aims: To collect detailed information about the usage of Brocchia cinerea

23-06-2024
Buenas prácticas de almacenamiento de medicamentos en el Hospital Escuela de Tegucigalpa, Honduras

Emilia C. Vargas (2024)

Context: The poor storage practices in warehouses and pharmacies may lead to drug degradation. Aims: To analyze the Good Storage Practices for medicines in the warehouse and pharmacies of the Hospital Escuela of Tegucigalpa, Honduras. Methods

23-06-2024
Molecular docking study of sea urchin (Arbacia lixula) peptides as multi-target inhibitor for non-small cell lung cancer (NSCLC) associated proteins

Muhammad Hermawan Widyananda (2024)

Context: Lung cancer is a type of cancer that causes the most deaths worldwide. The most common type of lung cancer is non-small cell lung cancer (NSCLC). Sea urchin (Arbacia lixula) has high potential as an antiNSCLC agent. Aims: To analyze the

23-06-2024
The effect of hyperbaric oxygen 2.4 absolute atmospheres on transforming growth factor-? and matrix metalloproteinase-8 expression during orthodontic tooth movement in vivo

Arya Brahmanta (2024)

Context: Orthodontic force causes the compression of the periodontal ligament in inhibiting vascularization on the pressure side of orthodontic tooth movement (OTM), while on the opposite side, the periodontal ligament is stretched. Hyperbaric

23-06-2024
Protective effect of propolis from Tigzirt on epirubicin-induced cardiotoxicity and nephrotoxicity

Sara Chaa (2024)

Context: Epirubicin (EPI), belonging to the anthracycline family, is one of the most effective chemo-therapeutic agents used in the treatment of a variety of solid and hematologic malignant tumors but Its anti-tumor efficacy is dose-dependent,

23-06-2024
Myricitrin from Physalis pubescens L. leaves and frankincense decrease resistance of MCF-7 cells and ameliorate efficacy of epirubicin

Suzy Abd El-Hakeem El-Sherbeni (2024)

Context: It was found that flavonoids and frankincense exert anti-cancer effect through their antioxidant and anti-inflammatory activities. Aims: To evaluate the cytotoxic effect against MCF-7 cells of flavonoids isolated from Physalis pubescens

23-06-2024
The effect of fresh goat's milk on anthropometric overview in healthy women

Yusni Yusni (2024)

Context: Most people believe that goat milk contains high fat; therefore, regular consumption of goat milk will increase body weight. This assumption needs to be proven to be able to utilize the use of milk to improve public health. Aims: To a

23-06-2024
The use of an antibiotic order form in a tertiary hospital: Influence on physicians’ prescribing patterns

Duc Chien Vo (2024)

Context: Vietnam is one of the countries at the high alert of antibiotic resistance. Aims: To evaluate the compliance rate and changes in physicians’ prescribing patterns in patients with community-acquired pneumonia (CAP) before and after u

23-06-2024
Antidiabetic, hypolipidemic, antioxidant and anti-inflammatory effects of Momordica charantia L. foliage extract

Alicia Lagarto Parra (2024)

Context: Momordica charantia (Cucurbitaceae) is extensively distributed in tropical areas, and it is traditionally used as antidiabetic. Nevertheless, few studies supporting the metabolic effects of its foliage extracts have been reported elsew

23-06-2024
Local Cuban bentonite clay as potential low-cost adsorbent for shark liver oil pool purification

Pedro C. Quero-Jiménez (2024)

Context: The shark liver of the species Ginglimostoma cirratun, Carcharhinus longimanus, and Carcharhinus falciformis, captured in the north-central coast of Cuba are a source of oil, that when extracted it must be purified due to its bad smell

23-06-2024
The increased basic fibroblast growth factor expression and osteoblasts number post Bifidobacterium bifidum probiotic supplementation during orthodontic tooth movement in Wistar rats

Ari Triwardhani (2024)

Context: Bifidobacterium bifidum as a beneficial probiotic may regulate the inflammation and induce the bone remodeling by enhancing osteoblasts and basic fibroblast growth factor (bFGF) expression in the tension side of alveolar bone during or

23-06-2024
Tea catechin as antiviral agent via apoptosis agonist and triple inhibitor mechanism against HIV-1 infection: A bioinformatics approach

Viol Dhea Kharisma (2024)

Context: Human immunodeficiency virus (HIV) antiretrovirals that target the binding of viral enzyme are chosen as the lead solution in the treatment of HIV-1 infection, such as non-catalytic site integrase inhibitor (NCINI), nevirapine, and daru

23-06-2024
Observancia de reacciones adversas y análisis de cumplimiento de bioseguridad en la aplicación rectal de ozonoterapia en pacientes cubanos con infección aguda o convalecientes de COVID-19

Lizette Gil del Valle (2024)

Context: Patients with COVID-19 present different biochemical and metabolic alterations from the acute state of infection until months later with variability of symptoms and increased toxicity of drugs related to oxidative stress according to p

23-06-2024
In vitro anti-aging activity of Muntingia calabura L. fruit extract and its fractions

Syamsu Nur (2024)

Context: Premature aging usually occurred due to free radicals reducing the skins’ physiological functions. Muntingia calabura, a plant containing rich antioxidants, has the potential to overcome this problem. Aims: To evaluate the antioxidant

23-06-2024
Insulin secretion and repairing pancreatic tissue damage on diabetic mice treated with the extract and active fraction of Hibiscus surattensis L. leaves

Yuliet (2024)

Context: Diabetes is a chronic health condition with insulin disturbance. Hibiscus surattensis L. is a medicinal plant and plays a pivotal role in diabetes. Aims: To evaluate the effect of H. surattensis leaves extract to increase insulin secr

23-06-2024
Molecular target mechanisms of celecoxib induced liver damage in rats and the potential prophylactic roles of melatonin and/or quercetin

Emtenan Sami Sulimani (2024)

Context: Celecoxib (Cele), a nonsteroidal anti-inflammatory drug (NSAID) is linked with a spectrum of hepatotoxic influences, however the underlying mechanism (s) by which this drug induces liver damage is still unexplored. Aims: To demonstrat

23-06-2024
Effects of commonly used medicinal herbs in Jordan on erythrocyte oxidative stress markers

Yousif Y. Bilto (2024)

Context: Much attention has been given recently to the antioxidant capacity of natural products, with particular interest on those that are frequently consumed by people. Aims: To evaluate the commonly used and frequently consumed edible herbs

23-06-2024
The rationale for methylene blue utility against SARS-CoV-2 infection complications

Gilberto L. Pardo Andreu (2024)

Context: Almost one year after the onset of COVID-19 pandemic in Wuhan, China and still no specific therapy has emerged, counting millions of dead worldwide. The association of an uncontrolled SARSCoV-2 replication and host-dependent mechanisms i

23-06-2024
The chemical composition of the ethanolic extract from Chromolaena odorata leaves correlates with the cytotoxicity exhibited against colorectal and breast cancer cell lines

Hanifah Yusuf (2024)

Context: Colorectal and breast cancer are of particular cellular preventive concern. WIDR cells are an indicator of colorectal cancer development, while HTB and 4T1 cells are involved in breast cancer. The Chromolaena odorata was reported to in

23-06-2024
Apoptosis via cytochrome c in aortic tissue of diabetes mellitus after giving sikkam leaves (Bischofia javanica Blume)

Syafruddin Ilyas (2024)

Context: Diabetes mellitus (DM) is a metabolic hyperglycemia disease caused by abnormalities in insulin secretion and the highest increase in diabetes sufferers that occurred in Southeast Asian countries, including Indonesia. The sikkam leaf (B

23-06-2024
The toxicogenic effect of Terminalia phanerophlebia Engl. & Diels leaf extract on oxidative stress parameters in an in vitro Hek293 model

Marcilyn R. Nyahada (2024)

Context: Medicinal plants are a highly sought-after alternative to current pharmaceutical drugs because they can be locally cultivated, inexpensive and possess minimal adverse effects. Given that Terminalia phanerophlebia (TP) possesses many use

23-06-2024
Seguridad del nimotuzumab luego de ensayos clínicos en tumores epiteliales de cabeza y cuello

Oneyda Clapé-Laffita (2024)

Context: Immunotherapy, by directing the immune response against tumor cells, complements the oncological therapy along with conventional treatments. Thus, the monoclonal antibody nimotuzumab blocks the binding of epidermal growth factor to its

23-06-2024
Khat-drug interactions: A systematic review

Nabil Ahmed Albaser (2024)

Context: Consumption of khat leaves has been disseminated worldwide with the migration of its users from Arabia and Africa. Despite numerous reports regarding the associations of khat chewing with serious health impacts, a significant number of

23-06-2024
In vitro proliferative activity of 6-substituted uracil derivatives

Stanislav A. Grabovskiy (2024)

Context: Previously, we investigated the relationship between the nature of the substituent at the 5-position of the uracil ring and the action of the corresponding uracil derivatives on immortalized lung cells. In the present study, we analyze

23-06-2024
Antioxidant and anti-advanced glycation end products formation properties of palmatine

Sharma Mridula (2024)

Context: Oxidative stress and formation of advanced glycation end products (AGEs), due to glycation of proteins, lipids and nucleic acids are characteristic in diabetic patients. Palmatine, a protoberberine alkaloid bioactive isolated from Coscin

23-06-2024
Factors that encourage cigarette consumption among college students: A theory of planned behavior perspective

Alejandro Valencia-Arias (2024)

Context: The numbers of cigarette smokers and deaths from this cause have grown rapidly in recent years. Different factors that increase cigarette smoking, college students have become a highly vulnerable population to smoking cigarette. Aims:

23-06-2024
Ethnomedicinal and traditional phytotherapeutic plants used in Bouhachem Natural Regional Park (Rif of Morocco): Case of Bni-Leit and Al-Oued districts

Mohammed Bachar (2024)

Context: The flora of the Bouhachem Regional Natural Park has been studied by many botanists and ecologists, but the analysis of the medicinal and economic values of these plants is still weak and poorly documented. Within the framework of this

23-06-2024
Ameliorative effect of Ruzu herbal bitters on high-fat diet induced non-alcoholic fatty liver disease in Wistar rats

Olubanke O. Ogunlana (2024)

Context: One of the world's most widespread and frequent liver diseases is the non-alcoholic fatty liver disease (NAFLD). Aims: To evaluate the preventives activities of Ruzu herbal bitters (RHB), which is an anti-obesity therapeutic concoction

23-06-2024
Complementary application of the ozonized saline solution in mild and severe patients with pneumonia COVID-19: A non-randomized pilot study

Adriana Schwartz (2024)

Context: Currently, there is no effective antiviral therapy recommended for novel coronavirus pneumonia 2019 (COVID-19). Aims: To assess the safety of ozonized saline solution (O3SS) used as a complementary therapy in adult COVID-19 patients. M

23-06-2024
Preventive and therapeutic effects of JM-20 on paclitaxel-evoked painful peripheral neuropathy in rats

Bárbara B. Garrido-Suárez (2024)

Context: JM-20 is a hybrid synthetic molecule, which is based on a multimodal drug design paradigm for cerebrovascular disease. In addition to its neuroprotective effects, JM-20 also decreased sciatic nerve chronic constriction injury (CCI)-ind

23-06-2024
Vernacular names of plants between diversity and potential risks of confusion: Case of toxic plants used in medication in the central Middle Atlas, Morocco

Mariame Najem (2024)

Context: Knowledge of medicinal plants is the first step in preserving traditional use and preventing intoxication. Aims: To highlight the risks of intoxication related to the similarities of vernacular names between medicinal plants and to conf

23-06-2024
The role of reduced glutathione on oxidative stress, reticulum endoplasmic stress and glycation in human lens epithelial cell culture

Nina Handayani (2024)

Context: Cataracts are currently the main cause of blindness worldwide. This condition caused by a low concentration of reduced glutathione (GSH) in the lens. Aims: To evaluate the effect of glutathione (GSH) on the hyperglycemiainduced oxidative

23-06-2024
Formulation and release of timolol maleate from ocusert based on gelatin-N-(3-dimethylaminopropyl)-N-ethylcarbodiimide polymer

Mohammed Q. Kanaan (2024)

Context: Glaucoma is a disease of the eyes characterized by an increase in the intraocular pressure. Timolol maleate is commonly used as eye drops for chronic glaucoma treatment. Aims: To formulate an ocusert (novel ophthalmic drug delivery syst

23-06-2024
Development and validation of a gas chromatography with a flame ionization detector method for quantitative analysis of four major fatty acids extracted shark liver oil

Pedro C. Quero-Jiménez (2024)

Context: The shark liver of the species Ginglimostoma cirratun, Carcharhinus longimanus, and Carcharhinus falciformis, captured in the north-central coast of Cuba are a source of oil, whose content of major fatty acids could be used in its qual

23-06-2024
Antioxidant activity of fractions isolated from hemolymph of garden snail Helix lucorum

Albena Alexandrova (2024)

Context: The snail hemolymph is a multi-component mixture comprising various substances with pharmacological activity. Aims: To evaluate the antioxidant activity of hemocyanin and fractions isolated of hemolymph from garden snail Helix lucorum.

23-06-2024
Aceite de hígado de tiburón microencapsulado: Desarrollo de una formulación de cápsulas duras

Caridad M. García Peña (2024)

Context: The recognized properties of shark liver oil support its use as a raw material, of natural origin, in pharmaceutical formulations. Aims: To develop a formulation of hard capsules containing microencapsulated shark liver oil, by spray dr

23-06-2024
Effect of pharmacist-led intervention on predictors of diabetic neuropathy at two different hospitals of Malaysia

Amer Hayat Khan (2024)

Context: Diabetes mellitus is a progressive disease. In poor glycemic control, it can cause severe and non-reversible complications. A proper educational intervention from health care providers is needed for patients to decrease the progression

23-06-2024
In utero exposure to Hypoxis hemerocallidea Fisch., C.A.Mey. & AvéLall. improves metabolic syndrome parameters in pregnant rats and offspring

Constance R. Sewani-Rusike (2024)

Context: Intrauterine and early life environments contribute to adult metabolic phenotype. Use of medicinal plants like Hypoxis hemerocallidea during pregnancy raises the question of whether this species may have epigenetic benefits or detriment

23-06-2024
Bioequivalence of two novel formulations of ivermectin 1% combined with fluazuron 12.5% for subcutaneous administration in cattle

Diego M. Robaina (2024)

Context: Ivermectin (IVM) and fluazuron are present as novel combinations to control ticks. Differences in formulations account for changes to the plasma kinetics and could change exposure of target parasites to active drugs. Aims: To evaluate

23-06-2024
The effect of Mentha piperita L. on the mental health issues of university students: A pilot study

Abeer R. Abdelhalim (2024)

Context: Stress, sleep disorders, and anxiety are common mental health problems affecting many university students. Peppermint, as a traditional herb, may be used as an alternative to stimulant drugs with less adverse effects to deal with menta

23-06-2024
The component analysis of liquid smoke from rice hulls and its toxicity test on baby hamster kidney cells

Ira Arundina (2024)

Context: The pyrolysis product of rice hulls (Oryza sativa) has been used for the natural preservation of food and shows the potential to act as an antioxidant and anti-inflammatory product. However, the safety of this treatment has still not b

23-06-2024
Pharmacist perceptions of patient care competency: A survey in Vietnam

Vo T. Ha (2024)

Context: In order to perform effectively in professional practice, a pharmacist should demonstrate crucial competencies on delivery of patient care. Aims: To evaluate current pharmacists’ perceptions on their delivery of patient care compete

23-06-2024
Composición química, capacidad antioxidante y actividad antiinflamatoria de los frutos de Mimusops coriacea (A.DC) Mig (Sapotaceae) que crece en Ecuador

Katherine E. Bustamante Pesantes (2024)

Context: Mimusops coriacea (Sapotaceae) is traditionally used to treat inflammation of the urethra, cystitis, diarrhea, and dysentery, among others. In Ecuador it is used as an analgesic and anti-inflammatory, however the phytochemical and pharm

23-06-2024
Phytochemical and anti-cancer properties of Euphorbia hierosolymitana Boiss. crude extracts

Yousef M. Al-Saraireh (2024)

Context: Euphorbia hierosolymitana is a member of Euphorbia species having a restricted use in traditional medicine in eastern Mediterranean countries. Aims: To phytochemically analyze different extracts of Euphorbia hierosolymitana and to inve

23-06-2024
Prediction of the physical stability and quality of O/W cosmetic emulsions using full factorial design

Yisel M. Navarro-Pérez (2024)

Context: Full factorial design is effective in predicting the properties optimization and processing conditions of cosmetic emulsions. However, in most factorial designs, the technological quality and accelerated stability tests of emulsions ar

23-06-2024
Secondary metabolites from Alphonsea tonkinensis A.DC. showing inhibition of nitric oxide production and cytotoxic activitySecondary metabolites from Alphonsea tonkinensis A.DC. showing inhibition of nitric oxide production and cytotoxic activity

Khan Viet Nguyen (2024)

Context: Bioactivities of Alphonsea tonkinensis A.DC have not been reported previously, while the knowledge about its chemical composition is limited. Aims: To investigate the phytochemical constituents and bioactivities of the stems and leave

23-06-2024
Variation of cytochrome oxidase-I gene and venom proteins of Rhopalurus junceus populations in the Moanicum sector: Pharmacological implications

Rodolfo Rodríguez-Ravelo (2024)

Context: In Cuba, the venom of the endemic scorpion Rhopalurus junceus has been used in traditional medicine for cancer treatment. The genetic variability in populations from distinct origin and differences in the composition of venom –a littl

23-06-2024
Anti-hyperglycemic and hypolipidemic effects of Saraca asoca (Roxb.) Wild. flowers in alloxan-treated diabetic rats

Ellappan Thilagam (2024)

Context: Saraca asoca (Leguminosae) has been widely used in the Ayurvedic system of medicine for various ailments, and it has been used to treat diabetes as a folk medicine. Aims: To investigate the anti-hyperglycemic and anti-hyperlipidemic e

23-06-2024
In-Silico Studies of Brucea javanica (L.) Merr. as Potential Inhibitors of Influenza A H5NI Neuraminidase

RINA F NUWARDA (2024)

The H5N1 avian influenza continues to be endemic in Indonesia, posing threats to the poultry farming industry and public health. Type A virus is the most lethal and frequently evolves resistance against NA drugs; therefore, the exploration of nov

23-06-2024
THE POTENCY MUCOADHESIVE GRANULES OF EXTRACT PREMNA OBLONGIFOLIA MERR. AS PEPTIC ULCER TREATMENT AGENT

TITA NOFIANTI (2024)

Green grass jelly (Premna oblongifolia Merr.) is abundant in Indonesia and is a traditional Indonesian food. Moreover, this plant is rich in fiber and antioxidant properties. The research aims to determine the influence of ethanol extract from gr

23-06-2024
Antibacterial Activity Test of Herbal and Non Herbal Bar Soap Against The Growth of Staphylococcus aureus ATCC29213

SUSI A RAHAYU (2024)

It is essential to maintain skin hygiene by removing dirt and bacteria, including Staphylococcus aureus. Soap is an effective method for maintaining clean skin, particularly antibacterial bar soap that incorporates triclosan (a non-herbal compone

23-06-2024
Local Hemostatic Activity of Several Varieties of Banana (Musa Paradisiaca) Pseudo-Stem Sap in Swiss Webster Mice

CSZAHREYLOREN VITAMIA (2024)

Skin injuries requiring local hemostatics for effective treatment.Indonesians have upheld the tradition of utilizing herbal, and one prominent example is the utilization of the banana tree (Musa paradisiaca) for its medicinal advantages. The purp

23-06-2024
TLC Video Densitometry Method for Determination Thiamphenicol in Dry Syrup

WINASIH RACHMAWATI (2024)

An analytical method for the determination of thiamphenicol in dry syrup has been developed by the TLC video densitometry method. Identification and quantification of thiamphenicol in simple pharmaceutical preparations were performed on a silica

23-06-2024
Behavioral Technology Acceptance Model In Health Care Industry: Systematic Literature Review

KAMELIA AGUSTINI (2024)

Identify the problems of several Research Gaps, namely the lack of breadth and depth in the Technology Acceptance Model (TAM) variables with other variables that will be tested, as well as potential variables that contribute to improvements to th

23-06-2024
Antioxidant Activity and Sun Protection Factor of Different Parts of Sawo Walanda (Pouteria Campechiana (Kunth.) B.) Extract

SANI N FITRIANSYAH (2024)

UV radiation can lead production of Reactive Oxygen Species (ROS) on the skin and can cause negative effects. Sun protector and antioxidant ingredients are needed to protect the skin. Phenolic compounds and flavonoids have been used as sun protec

23-06-2024
Hepatoprotective Activity of Binahong (Anredera cordifolia (Ten.) Steenis) Leaf Extract in Diabetes Mellitus Rats

JONI TANDI (2024)

Binahong (Anredera cordifolia (Ten.) Steenis) is efficacious in treating diabetes, heart disease, and high blood pressure. This study aims to determine secondary metabolite levels using UV-Vis spectrophotometry and evaluate antioxidant activity w

23-06-2024
Characteristics Of Domperidone Patch With Variation Of Penetration Enhancers (Isopropyl Myristate Or Eucalyptus Oil)

RAHMAH ELFIYANI (2024)

Domperidone shows low bioavailability values when administered orally so this compound is suitable for administration transdermally Penetration enhancer was one component that can increase the diffusion of domperidone which was formulated in patc

23-06-2024
Identification of Angiotensin Receptor Blocker II Ligands From Gotu Kola (Centella asiatica L.) Extract: an In Silico Study

DEDEN I DINATA (2024)

Noncommunicable diseases, such as hypertension, are a major cause of health problems in developed countries. Angiotensin receptor blocker (ARB) II is a common first-line therapy for hypertension. ARB works by blocking angiotensin II, which causes

23-06-2024
Comparison of Phenolic Content of Indonesian Bay Leaves (Syzygium polyanthum) Fresh Decoction And Herbal Tea

IRMA RAHMAWATI (2024)

The Indonesian bay leaves (Syzygium polyanthum) are one of the traditional cooking spices used in several countries in Southeast Asia, and this spice gives a distinctive herbaceous aroma. Bay leaves are often used as a medicinal plant for generat

23-06-2024
AVOCADO SEED EXTRACTS (Parsea americana Mill.) BIOACTIVE COMPOUNDS PROFILE AS A SOURCE OF ANTIOXIDANTS

SITI JUBAIDAH (2024)

The use of synthetic antioxidants in high doses is reported to be toxic and carcinogenic. Avocado seeds are not used because the waste in avocado seeds contains many phytochemicals. Research on avocado seeds has been carried out mainly as antioxi

23-06-2024
Formulation and Physical Stability Test Peel Off Mask from Kokang Leaf Extract (Lepisanthes amoena (Haask) Leenh) as an Antioxidant

JATI PRATIWI (2024)

Antioxidants are needed as an antidote to free radicals that can inhibit or neutralize the bad effects of free radicals and are formulated in the form of peel-off masks to remove dirt and dead skin cells. Kokang leaves (Lepisanthes amoena (Haask)

23-06-2024
In Silico and In Vitro Studies on Compounds in Turmeric (Curcuma domestica) as Anti-inflammatory for Cyclooxygenase-2 (COX-2)

DEVANI O WINARDI (2024)

Turmeric contains curcuminoid compounds which have been confirmed from various studies to have various benefits for the body, including antiviral, antibacterial, antioxidant, anticarcinogenic, and anti-inflammatory properties. Research on the eff

23-06-2024
Physical Properties of Peel-Off Gel Mask Ethanol Extract of Surian Leaves (Toona sinensis) as an Antioxidant

UCE LESTARI (2024)

Free radicals can cause damage to skin oxidative cells and affect aging. One of the compounds that can overcome the bad effects of free radicals is Antioxidants. Sources of antioxidants can come from nature, such as from surian leaves (Toona sine

23-06-2024
Antipyretic And Antiinflammatory Activities Of Bopot Leaf Extract From Kutai Kartanegara District

CHAERUL F MOCHTAR (2024)

Fever, a condition where the body temperature is above normal (> 37°C) can occur due to inflammation, an immune system response from harmful stimuli such as pathogens. Bopot leaves (Tabernaemontana divaricate L.) contain flavonoids, tannins, sap

23-06-2024
Formulation and Evaluation of Physical Characteristics of Ethanol Extract Capsules of Red Atai Tuber (Angiopteris ferox Copel)

ANDI N AISYAH (2024)

Paku atai merah (Angiopteris ferox Copel) is a fern plant native from Kalimantan. The Dayak tribe uses the tuber as a mixture of traditional medicines and has the potential to be an antioxidant. The tuber of paku atai merah contains secondary met

23-06-2024
Quality of Pharmaceutical Services on Patient Loyalty of RSUD Soewandhie Surabaya

IRA PURBOSARI (2024)

Quality of health services is an important thing. The level of perfection of a service to increase patient satisfaction. The quality of patient care is very influential on loyalty. The purpose of this study was to assess the quality of medical se

23-06-2024
Analysis of Vitamin C and Antioxidant Activity of Capsicum frutescens L. and Capsicum annuum L. (curly and large chili variety)

ST MARYAM (2024)

Vitamin C is a nutrient that the body needs in order to increase its metabolism. This helps the body to create collagen and also act as an antioxidant. This study aims to analyze of vitamin C and the antioxidant activity of Capsicum frutescens L.

23-06-2024
IN SILICO STUDY OF JAVA WOOD (Lannea coromadelica) AS ANTI-INFLAMMATORY IN TNF-? AND COX-2 MEDIATO

ANDI MUFLIHUNNA (2024)

Java wood (Lannea coromandelica) is a plant that is widely used empirically by people in South Sulawesi as a traditional medicine because it has pharmacological effects such as anti-inflammatory which is a normal protective response to various ph

23-06-2024
Formulation and Antioxidant Activity of Lip Balm Containing Banana Peel (Musa paradisiaca var. Sapientum) Methanol Extract

JASTRIA PUSMARANI (2024)

Banana peel (Musa paradisiaca var. Sapientum) contains flavonoid, phenolic, and tannin compounds as a high source of antioxidants. Antioxidants have been shown to hydrate, soften and reduce skin dryness, and have the potential to be lip balm form

23-06-2024
Antioxidant Activity of Extract Combination From Averrhoa bilimbi L. Leaves and Stingless Bee Honey

BUNGA P SARI (2024)

Averrhoa bilimbi L. leaves and stingless bee honey contains phenolic compounds that can act as antioxidants. This study aims to find out the antioxidant activity of extract combination from Averrhoa bilimbi L. leaves and stingless bee honey (Trig

23-06-2024
DEVELOPMENT STUDY OF NANOPARTICLE FORMULATION FROM DRAGON FRUIT(Hylocereus polyrhizus) SKIN EXTRACT AS A MOISTURIZER IN LIP BALM

YULIA YESTI (2024)

Dragon fruit peel (Hylocereus polyrhizus) is a waste that is rarely used and often thrown away even though dragon fruit peel contains many secondary metabolites, one of which is flavonoids which function as moisturizing agents in lip balm prepara

23-06-2024
Comparison of Extraction Solvents Towards Anti-Propionibacterium acnes activity of Alphitonia incana (Roxb). Teijsm. & Binn. ex Kurz Leaves

HAFIZ RAMADHAN (2024)

Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz locally known as Balik Angin in Borneo Island is one of the endemic plants that have the potential to be an alternative antibacterial agent. Balik Angin leaves contain secondary metabolites that h

23-06-2024
Flavonoids from Basil Leave as a Potential Inhibitor of SARS-CoV2 Main Protease: an In Silico Approach

FARHAN FIRMANSYAH (2024)

SARS-CoV2 a virus that caused the global pandemic Coronavirus 2019 (COVID19) has infected about 659.108.952 peoples, with 6.684.756 deaths in the world as stated by WHO on 23rd December 2022. Basil leaves have antiviral potential, especially in g

23-06-2024
Molecular Docking and Toxicity from Temulawak Rhizome (Curcuma xanthorrhiza Roxb.) against COX-2

MEILINDA S PRACEKA (2024)

Temulawak rhizome (Curcuma xanthorrhiza Roxb.) is a rhizome that comes from the Zingiberaceae tribe. Temulawak rhizome is commonly used as a traditional medicine in Indonesia as an antiinflammatory. The purpose of this study was to provide informat

23-06-2024
Formulation of Peel-off Gel Face Mask from Pandanus amaryllifolius (Roxb.) Leaves Extract

TUBAGUS AKMAL (2024)

UV exposure is the most significant environmental risk factor that can be altered for skin cancer and many other skin conditions. An antioxidant is a compound that can protect the skin from sun radiation. Pandanus amaryllifolius is a plant that h

23-06-2024
Antibacterial Activities of Guava Leaves and Klutuk Banana by In Vitro as Antidiarrhea

IRA RAHMIYANI (2024)

Klutuk banana fruit and red shoots of guava leave added with salt used by Batra in Jayaratu Singaparna Village to treat diarrhea. The green shoots of guava used by the community in treating diarrhea than klutuk bananas. This study aims to compare

23-06-2024
Antihyperuricemia Activity Of Kupa (Syzygium polycephalum) Seed Extracts In Male White Mice

IRA RAHMIYANI (2024)

Hyperuricemia is a clinical condition of increasing uric acid in the blood beyond normal. Increased levels of uric acid can accumulate monosodium urate crystals. Kupa fruit seeds contain flavonoids, saponins, tannins, and polyphenols which have a

23-06-2024
Physical Properties and Anti-Mosquito Activities of Lotion Male from Palm Flower Extract (Elaeis guineensis Jacq.)

M ARSITA (2024)

Mosquitoes can carry protozoa, viruses, and worm larvae that can cause various diseases in humans. Mosquito repellent preparations that are widely sold in the market are in the form of lotion preparations. However, most formulas of mosquito repel

23-06-2024
Sensitivity Assay of Resistant Escherichia coli to Fosfomycin, Kanamycin, Rifampicin, Ceftriaxone, Imipenem, and Vancomycin

TINA ROSTINAWATI (2024)

Antibiotic resistance is a major global health problem and continues to increase, so there is a need for better evaluation and therapeutic advice for Urinary Tract Infection (UTI) patients. It had isolated E. coli from clinical isolates that were

23-06-2024
FORMULATION AND CHARACTERIZATION OF BUCCAL FILM NANOEMULSION APIGENIN AS ANTIDIABETIC

LUSI NURDIANTI (2024)

Apigenin (4`,5,7-trihydroxyflavone) is a flavonoid of subclass flavones that have antidiabetic therapeutic activity but limitations BCS Class II low solubility of 2.16 ?g/L. To overcome these limitations, the development of nanoemulsion formulati

23-06-2024
Antioxidant Activities of Scrub Body Lotion Extract of Surian Leaves (Toona sinensis) with Powder Scrub Date Seeds (Phoenix dactylifera)

UCE LESTARI (2024)

Free radicals from exposure to ultraviolet radiation (UVB) cause dull, rough, dry, cracked skin and premature aging so that they can damage skin tissue and result in fatal skin cancer. To prevent this, antioxidants are needed. Plants that have po

23-06-2024
Molecular Docking Study: Phyllanthus niruri L.'s Active Compounds as Dengue Haemorrhagic Fever Therapy

RISKA PRASETIAWATI (2024)

Dengue Haemorrhagic Fever is a disease caused by the dengue virus through a mosquito vector Aedes aegypti. NS3 Helicase is known as one of nonstructural proteins consisting of some essential enzymes for virus replication. Nowadays ivermectin has

23-06-2024
In Silico Study of Cembranoid-Type Diterpene Targeting Kirsten Rat Sarcoma Virus (KRAS) Gene in Lung Cancer

TEUKU B SEPTIADY (2024)

Lung cancer is genetic changes in the V-Ki-ras2 gene Kirsten rat sarcoma viral oncogene homolog (KRAS), which is involved in signaling pathways related to proliferation, cell differentiation, and apoptosis. Point mutations in the KRAS gene were d

23-06-2024
Physical Stability of Sea Buckthorn Oil Nanoemulsion with Tween 80 Variations

AYU SHABRINA (2024)

Sea buckthorn oil (SBO) contains fatty acids that have an anti-aging effect. The delivery system of SBO can be improved by a nanoemulsion system. The purpose of this study was to determine the physical stability of SBO nanoemulsion (NSB) with Twe

23-06-2024
IDENTIFICATION OF ESSENTIAL OILS FROM THE BARK OF BALIK ANGIN (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz)

DYERA FORESTRYANA (2024)

One of the components that make up essential oils is phenolic compounds which are widely contained in the leaves and bark of the Balik Angin plant (Alphitonia incana (Roxb.) Teijsm. & Binn. ex Kurz). This study aimed to identify phenolic compound

23-06-2024
Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Basil (Ocimum basilicum) leaf essential oil contains terpenoid compounds that have antibacterial activity. This study aims to obtain hand cream preparations of basil essential oil, as well as to determine the effect of concentration variation of

23-06-2024
Radiochemical Purity Test of Fractionated Sestamibi Kit Labelled with Technetium-99m

HASNA CHOERUNISA (2024)

Coronary Heart Disease (CHD) is a heart disorder caused by blockage of blood vessels. CHD can be detected by Myocardial Perfusion Imaging (MPI). MPI is performed by injecting a radiopharmaceutical into the patient's body. 99mTc-sestamibi is a rad

23-06-2024
Total Phenolic and Flavonoid Contents and Antioxidant Activity of Kembang Bulan Leaves (Tithonia diversifolia (Hemsley) A. Gray)

NOER F RAHMAN (2024)

Many plants are used ethnomedicinally for the treatment of disease and restoration of health. One of these medicinal plants is Tithonia diversifolia. This study aims to determine the phenolic and flavonoid contents and antioxidant activity using

23-06-2024
Antidiabetic of Mango (Mangifera longipes Griff.) Leves: Methanol Extract, Water Fraction, and Ethyl Acetate

NUR RAHAYUNINGSIH (2024)

Mango leaves (Mangifera longipes Griff.) are used for diabetic, malaria, gastrointestinal, kidney, as well as topical treatment of wounds. The aim of this study was to determine the antidiabetic activity of methanol extract, water fraction and et

23-06-2024
Antidiabetic Potential Screening of Ulin Fruit Extract (Eusideroxylon zwageri) Against Streptozotocin-Induced Diabetic Rats

MUHAMMAD R FAISAL (2024)

Empirical evidence of complementary medicine from one community in Kalimantan often uses Ulin fruit (Eusideroxylon zwageri) for medical therapy or as herbal drinks by people with diabetes mellitus. This research aims to identify the antidiabetic

23-06-2024
Formulation of Gel Hand Sanitizer of Nagasari Leaf Extract (Mesua ferrea L.)

TUTI S SUHESTI (2024)

Nagasari (Mesua ferrea L.) is one of the biodiversity to be developed as an antiseptic preparation. These plants are known to contain flavonoid compounds, tannins, and terpenoids that act as antibacterial. Hand sanitizer gel preparations can incr

23-06-2024
Formulation and Antioxidant Activity of Clay Mask of Ethanol Extract Tamarillo (Solanum betaceum Cav.)

YESSI FEBRIANI (2024)

Tamarillo (Solanum betaceum Cav.) is a plant that is spread in Java, Bali, and North Sumatra, which is rich in nutrients and contain flavonoid as antioxidants that can prevent cell damage due to oxidative stress. Clay-based face masks have a firm

23-06-2024
Microscopic Identification and Determination of Total Flavonoid Content of Moringa Leaves Extract and Ethyl Acetate Fraction (Moringa oleifera L.)

ANNISA FATMAWATI (2024)

This research was conducted to identify simplicia microscopically, phytochemical screening and determination of total flavonoid content of extract and ethyl acetate fraction from Moringa (Moringa oleifera L.) leaves using UV-Vis Spectrophotometry

23-06-2024
Water Extract Influence of Stachytarpheta jamaicensis (L.) Vahl Leaves to Prevent Psoriasis Severity in Animal Model

ENCEP ABDURAHMAN (2024)

Psoriasis is an autoimmune disease that is characterized by the appearance of lesions on the skin. The current treatment aims to control the symptoms. The efficacy of Stachytarpheta jamaicensis (L.) Vahl’s for autoimmune rheumatoid arthritis an

23-06-2024
Formulation of Cinchona Extract (Cinchona succirubra) Cream and the Safety as Hair Fertilizer

HARIYANTI (2024)

Cinchona extract contains quinoline alkaloids, has telangiectatic activity, is practically insoluble in water so penetration into hair follicles is low, and requires a delivery system, namely cream. Purposed to determine the formula of cinchona e

23-06-2024
Anti inflammatory Activity of the Ethanol Extract of Cinnamon (Cinnamomum burmannii) Bark using Membrane Stabilization Method and Protein Denaturation

ANNISA SHALIHAH (2024)

Inflammation is the body's reaction to infection, irritation, or foreign substances, as the body's defenses. Inflammatory mediators such as bradykinin, prostaglandins, fluid extravasation, and tissue damage are essential to protect our body as an

23-06-2024
The Antiplaque Efficacy and Effectiveness of Activated Charcoal Toothpaste of Elaeis guineensis in Smokers

UCE LESTARI (2024)

Plaque on the teeth of smokers comes from cigarette smoke tar that settles on the surface of the teeth and roots of the teeth, causing the tooth surface to become rough and easier to stick with food debris and germs that will react making it easi

23-06-2024
Characterization of Nanosilver Biosynthesis by Citrus sinensis (L.) Osbeck and Peel-off Mask Formulation with Variation Polyethylene Glycol 400-Glycerin Concentration

DIAN E ERMAWATI (2024)

Sweet orange contains flavonoids and citric acid that have the potential as a capping agent in the nanosilver biosynthesis process. The antibacterial activity of silver can be increased in nanoparticles, then it can be applied to treat acne throu

23-06-2024
Binding Mode and Molecular Dynamics of Epigallocatechin and Epigallocatechin Gallate with Superoxide Dismutase-1

LIDYA C BAWONO (2024)

Superoxide dismutases (SODs) are metalloenzymes that defend the body against reactive oxygen species. Human cells have three distinct SODs, i.e., MnSOD, ECSOD, and Cu-ZnSOD (SOD1). Camellia sinensis L. leaves contain polyhydroxylated polyphenols

23-06-2024
Biomolecular Mechanism of Herbal Medicine on Muscle Atrophy in Type 2 Diabetes Mellitus Rats: Systematic Review

ASEP KUSWANDI (2024)

Elevation in proinflammatory phenotype, oxidative damage, and advanced glycation end products are brought on by musculoskeletal atrophy and can result in both micro- and macrovascular problems. Sarcopenia may result from this loss of skeletal mus

23-06-2024
The Effect of Ginger, Lemongrass, Clove Extract Ointmenton Diabetes Mellitus Wound Healing

NURWAHITA (2024)

The combination of ginger, lemongrass and cloves (JaSeKeh) which contains bioactive substances such as alkaloids, flavonoids, saponins, phenolic acids, terpenoids and eugenol compounds has the effect of lowering glucose levels in the blood. Objec

23-06-2024
Determination of Gamma Oryzanol from Ethanolic Extract of Indonesian Rice Bran (Oryza sativa)

AFIFAH K VARDHANI (2024)

Rice bran contains gamma oryzanol, a chemical compound mostly consisted of complex ester transferulate with phytosterols. Gamma oryzanol has a strong antioxidant activity, explained by the free radical scavenging activity. This study was aimed to d

23-06-2024
Formulation of Manjakani Galls Extract Gel Soap Using Tragacanth and Carbopol 934

FITH K NURSAL (2024)

Manjakani galls (Quercus infectoria) can be used as an active ingredient in feminine hygiene soap compositions due to their tannic components. Tragacanth and carbopol 934, which are two gelling agents, can be used to gel soap. This study aimed to

23-06-2024
POTENTIAL OF RED BETEL LEAVES (Piper crocatum) AS TYROSINASE INHIBITOR IN SILICO AND IN VITRO

SYAHRUL MUSTOPA (2024)

Melasma is a pigmentation disorder caused by excess melanin synthesis in the form of brown patches around the face or neck. Melasma can affect all racial groups, especially areas with high ultraviolet radiation. Substances that are often used to

23-06-2024
Antioxidant Potential, Anti-Diabetes, and Toxicity of Aceh Cinnamon Extract (Cinnamomum burmannii)

SUHAILA (2024)

Cinnamon ums often used empirically to overcome diabetes. This study aims to assess the effectiveness of Aceh cinnamon extract as an antioxidant and antidiabetic in vitro and to evaluate the toxicity of the extract. Cinnamons, obtained from coffe

23-06-2024
Subchronic Toxicity Evaluation of Cincalok Oil Towards Wistar Rats Haematology

FAJAR NUGRAHA (2024)

Cincalok is a fermented shrimp product which has the potential to be used as pharmaceutical preparations. LD50 test results indicate that the substance is practically non-toxic. However, subchronic toxicity tests have not been performed. Therefor

23-06-2024
POTENTIAL OF RED BETEL LEAVES (Piper crocatum) AS TYROSINASE INHIBITOR IN SILICO AND IN VITRO

SYAHRUL MUSTOPA (2024)

Melasma is a pigmentation disorder caused by excess melanin synthesis in the form of brown patches around the face or neck. Melasma can affect all racial groups, especially areas with high ultraviolet radiation. Substances that are often used to

23-06-2024
THE EFFECT OF GALANGA RHIZOME (Kaempferia galanga L) EXTRACT ON THE MICE’s MAMMARY GLANDS

SARA NURMALA (2024)

Galanga Rhizome (Kaempferia galanga L) contains alkaloids, flavonoids, saponins and steroids which have the potential to stimulate the hormone oxytocin which has the function of stimulating prolactin. The habit of consuming is often found in preg

23-06-2024
ANTIOXIDANT ACTIVITIES OF ETHYL ACETATE EXTRACT OF KESAMBI (Schleichera oleosa L.) WITH DPPH METHOD

NURSAMSIAR (2024)

Kesambi (Schleichera oleosa) is one of the plants from Indonesia that has the potential as a medicineactive compound that is a potent antioxidant. The purpose of this study was to determine the potential of various parts of kesambi as an antioxidan

23-06-2024
Analysis of Flavonoids on Fraction from Hydrolysate of Cordia Sebestena L. Leaves Extract

NI P E HIKMAWANTI (2024)

Cordia sebestena L. contains flavonoids, that play a role in free radical scavenging activity. This study aimed to analyze the flavonoids in the hydrolyzed fraction of the 70% ethanol extract of Cordia leaves. The study was divided into 7 stages:

23-06-2024
Formulation And Charachterization of Nanoemulsion from Brucea javanica Seed Extract

WAHIDA HAJRIN (2024)

The anti-inflammatory of B. javanica needs to be made into a topical preparation. The bioavailability and stability of the active substance is a limitation in its use thus it is necessary to develop an appropriate formula. Nanoemulsion can increa

23-06-2024
Tea Fermentation of A. malacencis with Lactobacillus plantarum as a starter: In vitro study as a functional drink

PRATIWI APRIDAMAYANTI (2024)

Some herbal teas contain antioxidant compounds that can neutralize the free radicals. Aquilaria malaccencis is used to make teas in Indonesia and other countries and has been identified having antioxidant properties. This study aimed to determine

23-06-2024
Anti-Inflammatory Activity of Ethanolic Extract Melophlus sp. and Callyspongia sp. from Southeast Sulawesi

ADRYAN FRISTIOHADY (2024)

Marine sponges display significant potencies as an anti-inflammatory agent. Thus, this study aims to investigate the effect of anti-inflammatory of Melophlus sp. and Callyspongia sp. by decreasing plasma IL-1? levels of rats. This study was condu

23-06-2024
Cardioprotective activity of Apples Juice on Isoproterenol-Induced Myocardial Infarction in Rat

NENG F KURNIATI (2024)

Myocardial infarction was local necrosis of heart tissue due to reduced oxygen supply because of the occlusion of coronary arteries. Fruits could reduce the risk of developing obesity and CVDs. Several studies have shown that apples had a strong

23-06-2024
Production of Anti-Recombinant Human Insulin Antibody and Validation by Indirect ELISA

CHRISTY AMBARSARI (2024)

Human insulin potential has become an interest and is important in maintaining the success of therapy in patients with the availability of chemical-based analytical methods, however, only a few have been using immunoassays. This study aimed to pr

23-06-2024
Study of Solvent Type Effect on Preparation of Ethyl Cellulose Microparticles

MUAIMIN MUAIMIN (2024)

The purpose of this study was to investigate effect of solvent type on solidification rate of ethyl cellulose (EC) microparticles and particle size/distribution of emulsion droplets/hardened microparticles during solvent evaporation process using

23-06-2024
ANTI-ACNE PATCH FORMULATION SILKWORM COCOON WASTE WITH HPMC AND PVP VARIATIONS

MARIA ULFA (2024)

Some topical preparations for acne have been developed in the form of gels and creams. However, it is still rarely developed in the form of a patch dosage form. Waste from silkworm cocoons has the activity of inhibiting the growth of acne-causing

23-06-2024
Diuretic Effect of Combination of Watercress (Nasturtium officinale) and Purslane (Portulaca oleraceae)

AFIFAH B SUTJIATMO (2024)

Watercress (Nasturtium officinale) and purslane (Portulaca oleracea) are used to increase urination. This preclinical study aims to prove the diuretic effect of a combination of watercress and purslane extracts. Simplisia of watercress and pursla

23-06-2024
Antidiabetic activity of matoa leaves (Pometia pinnata J.R.Forst & G. Forst) extract on hyperglycaemic alloxan-induced rats

ARIFAH S WAYUNI (2024)

Matoa (Pometia pinnata J.R.Forst & G. Forst) leaves contain polyphenols and flavonoids which are prospective for the development of the new antidiabetic agent. This research aimed to explore the potency of matoa leaves in reducing blood glucose l

23-06-2024
Development of Metformin and Glimepiride Analysis Methods Using TLC-Spectrofluorometry

SALSABILA ADLINA (2024)

Diabetes mellitus (DM) is a chronic metabolic disorder disease. DM presents in two main types 1 and 2. Type 2 DM was caused by genetic and lifestyle which was the biggest contributor to DM cases. Many patients with type 2 DM treated with combinat

23-06-2024
Formulation of Blush on Cream from Roselle (Hibiscus sabdariffa L.) Flower Extract with Olive Oil as Emollients

TUBAGUS AKMAL (2024)

Natural dyes have become more popular as a result of the harmful and carcinogenic effects of synthetic dyes. Anthocyanins are natural dyes that are widely used to replace synthetic dyes and can also act as antioxidants that can be found in rosell

23-06-2024
Evaluation of Antioxidant Activity of Vernonia amygdalina Leaves and Its Flavonoid-Phenolic Content

MUAMMAR FAWWAZ (2024)

Bitter leaf, Vernonia amygdalina (VA), is used in various alternative medicine in several countries, including Indonesia. This study aims to evaluate the antioxidant activity of VA leaves by three different in vitro methods. The antioxidant activ

23-06-2024
Molecular Docking of Red Betel Leaf Bioactive Compounds (Piper crocatum) as Lipoxygenase Inhibitor

FERNANDA CHAIRUNISA (2024)

Degenerative diseases occurred due to several risk factors that are directly related to inflammation which affected several diseases such as coronary heart disease (CHD) and diabetes. One of the inflammatory causative agents is leukotrienes produ

23-06-2024
Nano-extract of Acalypha hispida Increased Cu,Zn-SOD Antioxidant in Pancreas of Diabetic Rat

HAMZAH ALFARISI (2024)

Nanotechnology has rapidly grown in various research fields to treat oxidative stress in diabetes, including medicine and phytomedicine. Previous research showed that Acalypha hispida has strong antioxidant activity in vitro and anti-hyperglycemi

23-06-2024
Activity of Kersen (Muntingia calabura L.) and Kasturi (Mangifera casturi Kosterm.) Extract as Afrodisiac

KARUNITA I ASTUTI (2024)

Kasturi (Mangifera casturi Kosterm.) is a typical plant of South Kalimantan, and Kersen (Muntingia calabura L) contains flavonoids and steroids was empirically used for aphrodisiac. However, no preclinical trials using that extracts. This researc

23-06-2024
Evaluation of Patch Ethanol Extract of Zingiber officinale Rosc. Var Amarum For Antiemetic

ARINI SYARIFAH (2024)

Shogaol and gingerol in ginger, can act as antiemetic. Ginger extract (Zingiber officinale Rosc. var Amarum) was formulated by patch transdermal to increase the effectiveness of therapy and to minimize the side effects. Method : maceration with e

23-06-2024
Formulation and Characterization Liposome of Oxcarbazepine

DINA P WIJAYA (2024)

Oxcarbazepine (OXC) was used as first line therapy or additional therapy for treatment of partial and secondary of seizures. The penetration of OXC into nasal mucosa can be enhanced by forming liposome. This research has the aim to prepare and ch

23-06-2024
Phenolics and Flavonoids Content of Epiphyllum oxypetalum (DC.) Leaves Fractions using Microplate Based Assay

NI P E HIKMAWANTI (2024)

Epiphyllum oxypetalum (DC.) or Wijaya Kusuma (Cactaceae) is an ornamental plant which is known to contain polyphenol compounds. The purpose to determine the levels of total phenolic and flavonoid compounds in the fractions of Wijaya Kusuma leaves

23-06-2024
Antibacterial Activity of Rosemary Oil Against Propionibacterium acnes and The Formulation into Nanoemulsion System

SANI E PRIANI (2024)

Acne is an inflammatory condition of the pilosebaceous unit that can occur due to infection of Propionibacterium acnes. Rosemary essential oil contains various active compounds that have antibacterial activity. Nanoemulsions have been developed a

23-06-2024
Subcronic Toxicity Of Moringa Leaf Extract (Moringa Oleivera L) On Histopathology Heart Organ Of Rats

YUNDA P LISTIANI (2024)

Moringa leaf (Moringa oleivera L) is a plant that has benefits as a natural medicinal ingredient. Benefits of Moringa leaves as anti-inflammatory, antimicrobial, antioxidant, antihypertensive, anticholesterol and antidiabetic. Phytochemical test

23-06-2024
Potency of Honje Hutan Flowers (Etlingera Hemisphaerica (Blume) R.M.Sm.) as Alpha-Glucosidase Inhibitor

SORAYA RIYANTI (2024)

The Pangandaran people process honje flowers into fresh drinks that are consumed for health. The forest honje leaf extract provides antidiabetic activity at a dose of 0.39 mg/g BW can reduce blood glucose levels by 36.16% has been reported. Limit

23-06-2024
Analysis of Waste Minimization in Production Time to Increase Production Effectiveness

NALIA E ISMAIL (2024)

Lean manufacturing has been widely applied in the industry as an effort to utilize resources efficiently and systematically. The purpose of this study is to analyze waste time activities and to proposed minimize the time so it will increase the e

23-06-2024
Molecular Docking Analysis of Volatile Compounds from Fraction of Eichhornia crassipes Herbs Ethanol Extract As ?-Glucosidase Inhibitor

DINIATIK (2024)

Diabetes mellitus is a degenerative disease characterized by an increase in blood sugar (hyperglycemia). Inhibiting it will prevent the uptake of glucose in the plasma. One of the plants that can be used as antidiabetic is E. crassipes herbs. Thi

23-06-2024
Antimalarial Activity of Ethanol Extract of Sampare Leaves (Glochidion sp var. Biak) Against Plasmodium falciparum In Vitro

KHAIRUDDIN KHAIRUDDIN (2024)

Malaria is one of the health problems in the world and in Indonesia. This disease is caused by the protozoan parasite, the genus Plasmodium. Plasmodium falciparum is the most important parasitic disease with high morbidity and mortality in the wo

23-06-2024
Design and Cloning of Gene Encoding SLPI C-Terminal Domain in Escherichia coli TOP10

EVI UMAYAH ULFA (2024)

Elevated levels of neutrophil elastase in CPOD (Chronic Obstructive Pulmonary Disease) airways are regarded as the main trigger of lung destruction and inflammation. SLPI (Secretory leukocyte protease inhibitor), an inhibitor protease, represents

23-06-2024
Antibacterial Activity of Mangosteen Leaf and Bark Fraction Against Salmonella spp Causes Diabetic Ulcers

SALMAH WILUJENG ANGGRAINI (2024)

Diabetes mellitus is a degenerative disease due to impaired cell function ?-pancreas in insulin production causing hyperglycemics accompanied by microvascular complications such as diabetic ulcers. This condition is aggravated by bacterial contam

23-06-2024
Accute Toxicity of Extract from Melinjo (Gnetum gnemon L) Leaf with Fixed Dose Procedure Method

AYU ADELIA LESTARI (2024)

Melinjo leaves has several benefits as antidiabetic, antihyperglycemia, antioxidant and diuretic. In this experiment the acute toxicity test of ethanol extract of melinjo (Gnetum gnemon L). leaves on male white rats of wistar strain with fixed do

23-06-2024
Virtual Screening of Flavonoid Compounds as A Main Protease Inhibitor for Anti-Sars-Cov-2 Candidates

SAEFUL AMIN (2024)

In 2019, the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) was discovered in Hubei Province, China. After one year, no drug therapy has been approved, necessitating the development of SARS-CoV-2 drugs. To screen new drug candidates

23-06-2024
Knowledge and Perception of Self-Medication of Cough Medication in Pedicab Drivers in Surabaya

AMELIA LORENSIA (2024)

Pedicab drivers who are exposed to pollution and have a smoking habit are at high risk of developing COPD (chronic obstructive pulmonary disease). The initial disturbance that occurs is a decrease in lung function which often causes complaints of

23-06-2024
Authentication of Lemongrass Oil By Gas Chromatography-Mass Spectroscopy (GC-MS) Combination Chemometrics

HUSNUN K PRATIWI (2024)

The addition of something foreign to lemongrass essential oil has been done since ancient times. One way is to add turpentine oil which aims to increase the volume and grade of the smell. The purpose of this study was to determine the authenticat

23-06-2024
Identification of Antibiotic-Producing Isolates from the Soil of Pesantren Darul Aman Gombara, Makassar

FHAHRI MUBARAK (2024)

One source of antibiotics-producing microorganisms that are now widely used as a treatment for infections comes from the soil. Soil is an excellent medium for the growth and development of various microorganisms. The search for new antibiotics is

23-06-2024
Isoniazid Microencapsulation with HPMC HP-50 and HPMC HP-55 (2:3) Coating Using Solvent Evaporation Methods

HESTIARY RATIH (2024)

The combination formulation of tuberculosis drugs may cause interactions if drugs are given simultaneously. Rifampin (RIF) decomposes in the stomach when given concurrently with isoniazid (INH), which results in a decrease in the bioavailability

23-06-2024
Red Ginger (Zingiber officinale var. rubrum) Infusion in Improve COPD Symptoms

AMELIA LORENSIA (2024)

Chronic obstructive pulmonary disease (COPD) is a major global health problem and has an impact on increasing health costs and decreasing productivity. Red ginger infusion (Zingiber officinale var. rubrum) is one of the most widely consumed medic

23-06-2024
Molecular Docking of Bioactive Compounds from Wungu Leaves (Graptophyllum pictum (L) Griff) as Tyrosinase Inhibitors

ABDUL AZIZ (2024)

Melasma is characterized as a skin disorder by hyperpigmentation of the skin in areas exposed to sunlight. Currently, melasma treatment and cosmetic applications as a whitening agent were carried out by regulating tyrosinase activity through the

23-06-2024
Anti-obesity Potency of Chili Extract in Male White Rat

SISKA SISKA (2024)

Obesity is a global epidemic for non-communicable diseases characterized by a body mass index more than 30 kg/m2. Epidemiological data show that consuming foods containing capsaicin, the main active compound and causes a spicy taste in chili asso

23-06-2024
Formulation and Evaluation of Silver Nanoparticles Gel

CITRA ARIANI EDITYANINGRUM (2024)

Silver nanoparticles are known to be able to penetrate the cell membranes of acne-causing bacteria and cause structural damages that result in bacterial cell death. Silver nanoparticles need to be formulated in the form of a gel to make it easier

23-06-2024
Interactions of Perisbivalvin, Apioside, and Pelargonidine 3-Sambubioside Against PTGS2 Receptors

KETUT A ADRIANTA (2024)

Inflammation is a normal protective response to tissue injury and involves various physiological processes in the body. This study used the prostaglandin synthase 2 (PTGS2) receptor or cyclooxygenase-2 (COX2) which contributes to prostaglandin synt

23-06-2024
Development and Characterization of Orally Ibuprofen Self Emulsifying Drug Delivery Systems (SEDDS)

FITRIANTI DARUSMAN (2024)

Self-emulsifying drug delivery systems (SEDDS) were developed as a method to increase lipophilic drug solubility such as ibuprofen, and to increase the absorption and rate of drug dissolution. Therefore, the purpose of this study is to develop a

23-06-2024
Mechanical Properties Improvement of Dexibuprofen through Dexibuprofen Caffeine Co-crystal Formation by Ultrasound assisted Solution Co-crystallization Method

FIKRI ALATAS (2024)

The ability of an active pharmaceutical ingredient to be compressed is directly affected by its mechanical properties, such as flowability and tabletability. The characterization of the co-crystal formation included crystal morphology, powder X-r

23-06-2024
Antimicrobial Activity of Clerodendrum paniculatum L. n-Hexane and Water Fraction Against Pseudomonas aerugonisa and MRSA

DEWI PERTIWI (2024)

There are many medicinal plants have been recognized as sources of natural antimicrobial compounds that are used as potentially effective alternatives in the treatment of bacteria. Clerodendrum have been investigated for it is antimicrobial activ

23-06-2024
Preparation of Moisturizing Lotion Containing Silkworm (Bombyx mori L.) Sericin Nanoparticles

AULIA F HIDAYAT (2024)

Sericin as one of two main proteins in silkworm (Bombyx mori L.) cocoons was found to have the ability to increase skin moisture in cosmetics. The objective of this study was to determine the optimal formula of sericin nanoparticle lotion and the

23-06-2024
Volume Variation of Sweet Orange (Citrus sinensis) Juice and Peel Extract Toward the Characteristic and Antibacterial Activity of Nanosilver

DAVID SARONO PUTRO (2024)

Biosynthesis of nanosilver by using sweet orange (C. sinensis) as a bioreductor has shown nanosized results. In this research, the effect of volume variation of sweet orange juice and peel extract combination toward the characteristics and antibact

23-06-2024
Antibacterial Activity of Fraction of Allium cepa L. Tubers

MELZI OCTAVIANI (2024)

Shallots (Allium cepa L.) can not only be used as a seasoning in cooking, but also used as a medicine by the Indonesian people. The part of plants that can be used as a medicine are part of the tubers. Shallot tubers contain secondary metabolites

23-06-2024
Formulation of Liquid Soap Contains Cow's Milk from Middle Small Enterprise in Cimahi

TITTA H SUTARNA (2024)

The skin as part of the body often exposed to foreign objects and requires nutrition and regular cleaning using soap. Cow's milk, contains protein and fat, effectives to moisturize and nourish the skin. This study aims to make liquid soap prepara

23-06-2024
Isolation of Estuary Soil Fungi and Screening Antibacterial Activity Against Staphylococcus aureus

AFRIAN ROSYADI (2024)

Infectious disease is one of the causes of death in the world. Antibiotics are often used in the treatment of bacterial infections but are currently experiencing resistance. Based on this, the search for alternative antibiotics from natural sourc

23-06-2024
Determination and Purification of Ricin Protein from Ricinus communis L. Seeds using CLC (Column Liquid Chramotagoraphy) and FPLC (Fast Protein Liquid Chramatography)

IRMA ERIKA HERAWATI (2024)

Ricin is the most toxic substance isolated from Ricinus communis L. seeds. It is a heterodimeric twodomain polypeptide protein that includes chain A (30 kDa) and chain B (35 kDa) linked by a disulfide bond. Ricin binds to cells by the B chain and i

23-06-2024
Gastroprotective Effect of Ethanol Stem Bark Extract of Pepolo (Bischofia javanica Blume) Against Aspirin-Induced in Wistar Rat

YULIET SUSANTO (2024)

Prolonged use of nonsteroidal anti-inflammatory drugs (NSAIDs) can trigger ulcers in the gastric mucosa. Pepolo stem bark (Bischofia javanica Blume) has been empirically used to treat gastric ulcers. This plant contains alkaloids, flavonoids, tan

23-06-2024
Analytical Method Development of Quantification and Dissolution Assay of Ursodeoxycholic Acid Capsule

WANTI MEGAWATI (2024)

Ursodeoxycholic acid is an active compound to treat cholesterol gallstones and included in Biopharmaceutical Classification System c lass II. Ursodeoxycholic a cid c apsule f ormulations have been developed by the pharmaceutical industries. Due t

23-06-2024
Protective Activity of Muntingia calabura Fruits Extract Against Aspirin - Induced Gastric Ulcer in Rats

CYNTHIA A PUTRI (2024)

Gastric ulcer can be affected people at any age. One cause of this disease is NSAID usage. The aim of this study is to determine Muntingia calabura L. fruit extract activity for prevent ulcer using aspirininduced gastric ulcer in rat model. Thirty

23-06-2024
Antioxidant Activity and Cytotoxicity Against WiDR Cell and Vero Cell of The Karamunting (Rhonomyrtus tomentosa L.) Leaves Ethanol Extract.

MARWATI (2024)

Karamunting (Rhodomyrtus tomentosa L.), a plant used as a traditional medicine, is widely distributed throughout Indonesia. Karamuting has the potential as an antioxidant and anticancer agents because of its phenolic and flavonoid components. Thi

23-06-2024
Isolation and Characterization of Chemical Compounds From n-Hexane Extract of Zodia (Evodia suaveolens Scheff.) Leaves

MUTAKIN (2024)

Zodia (Evodia suaveolens Scheff.) (Rutaceae) is one of Indonesia's native plants, which comes from Papua which is widely used as traditional medicine. Empirically, zodia leaves are used as anti-mosquitoes, dysentery drugs, boiled bark is useful a

23-06-2024
Antibacterial Activity of Parijoto (Medinilla speciosa Blume) Fruit Against Serratia marcescens and Staphylococcus aureus

TIANA MILANDA (2024)

Parijoto (Medinilla speciosa Blume) is a plant found in Mount Muria, Kudus, Central Java. The local community often uses its fruit to treat various diseases, as well as antibacterial, anti-inflammatory, antioxidant, and anti-cancer. This study ai

23-06-2024
Piroxicam Percutaneous Permeation from Gels Through Membrane Models of Shed Snakeskin and Cellulose

ANIS Y CHAERUNISAA (2024)

Skin has a very important role in determining percutaneous absorption of active substance in topical administration. Study on percutaneous permeation of piroxicam from gel had been conducted using Franz Diffusion Cell with membrane model of shed

23-06-2024
Tyrosinase Inhibition from Green Tea (Camellia sinensis (L.) Kuntze) gel

HANIFAH RAHMI (2024)

Green tea (Camellia sinensis (L.) Kuntze) leaf has polyphenol substance that able to inhibit tyrosinase enzyme. Tyrosinase enzyme is one of the essential components that can be initiated melanin formation on the skin (melanogenesis). The natural

23-06-2024
Acute Oral Toxicity of Cincalok Oil in Wistar Rats

SITI N NURBAETI (2024)

Cincalok is a West Kalimantan traditional fermented food that has an opportunity to be developed into supplement products as a source of omega 3 and astaxanthin. This study was designed to observe the acute toxicity of Cincalok oil in female rats

23-06-2024
Molecular Docking Study of Anthocyanidin Compounds Against Epidermal Growth Factor Receptor (EGFR) as Anti-Lung Cancer

RISKA PRASETIAWATI (2024)

It is presumed that antiproliferative activity of anthocyanidin has interaction with Epidermal Growth Factor Receptor (EGFR) which has effect on lung cancer cell growth. This study aimed to observe the interaction between anthocyanidin and EGFR a

23-06-2024
In Silico Study of Compounds Contained in Hemigraphis alternata Leaves against 5-LOX for Anti-Inflammatory

YENI YENI (2024)

Inflammation is a self-protection response to begin the healing process. One of the anti-inflammatory targets worth developing is lipoxygenase inhibitors, which have been studied for several diseases, including severe airways disease. The aim of

23-06-2024
Antiviral Activity and Toxicity Prediction of Compounds Contained in Figs (Ficus carica L.) by In Silico Method

SHOPI DAMAYANTI (2024)

Viral infection is a global health problem that can cause endemic to a pandemic. Compounds delivered from plants has been developed as an alternative antiviral agent. One of the plants that can be used as antiviral therapy is Ficus carica L. (fig

23-06-2024
Formulation and Physical Evaluation of Edible Film Dosage from Ethanol Extract of Betel Leaves (Piper betle L) for Canker Sore Drugs

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Canker sore which in medical terms is called aphthous stomatitis is a wound in the mouth that can cause pain and discomfort. Piper betel leaf can be used for strengthening the teeth, cure canker sores, treat the bad breath and stop the gum from b

23-06-2024
The Effect of Chilli Extract on Gastroprotective Function in Male

TAHYATUL BARIROH (2024)

Chilli is one of plant from genus Capsicum and as vegetable commodities most consumed by the Indonesian people. Chilli contains a unique compound called capsaicin which gives a burning sensation like burning when consumed. This research aims to d

23-06-2024
Antiproliferation Assay of Essential Oil of Curcuma Rhizoma (Curcuma xanthorrhiza Roxb.) Against P388 Leukemia Cell

IDA MUSFIROH (2024)

Leukemia or blood cancer is a disease which marked by abnormal increasing of blood producer`s cells. Chemotherapies which used as anticancer have a many adverse effect and toxicity. The volatile oil of turmeric rhizome (Curcuma xanthorriza) conta

23-06-2024
Activity Screening and Structure Modification of Trigonelline as New Anticancer Drug for Non Small Cell Lung Cancer Through In Silico

KELVIN F PRATAMA (2024)

The biggest case of death in 2018 is caused by lung cancer. Non-small cell lung cancer (NSCLC) is most common. One of the cause lung cancer is the over expression of EGFR. Erlotinib is the first line of anticancer for NSCLC with EGFR mutations. H

23-06-2024
Effect of Administration of Combination of Captopril and Celery Extract on Blood Pressure and Electrolyte Levels of Hypertensive RatsEffect of Administration of Combination of Captopril and Celery Extract on Blood Pressure and Electrolyte Levels of Hypertensive Rats

SISKA SISKA (2024)

Based on previous reports, the combination of captopril and celery could reduce blood pressure in hypertensive patients. This study aimed to investigate the changes of blood pressure, urine volume, sodium, and potassium level, due to concomitant

02-06-2024
The Effectiveness of Aloe vera Hydrogel Against Fusobacterium nucleatum

CHANDRA SUSANTO (2024)

Bacteria can cause infectious diseases on oral health such as gingivitis and periodontitis. Scaling and rootplaning are effective against this disease, nevertheless several types of antimicrobial material can be added to increase the effectivenes

23-06-2024
In Silico Analysis of Physical-Chemical Properties, Target Potential, and Toxicology of Pure Compounds from Natural Products

PURNAWAN P PUTRA (2024)

Several studies have shown that pure compounds from west sumatera medicinal plants have beneficial therapeutic effects so that they are potential candidates for active pharmaceutical ingredients (API). Andalas Sitawa Fitolab has been able to prod

23-06-2024
Method Validation of Chloramphenicol Analysis in the Shrimp Based on Diazotization Reaction

ABDUL WAFI (2024)

A simple, rapid and precise spectrophotometric method has been developed and validated for the determination of Chloramphenicol (CAP) in the shrimp based on diazotization reaction at room temperature. The CAP was reduced by zinc powder and the di

23-06-2024
Characterization of Diazepam Imprinted Polymer with Methacrylic Acid and Hydroxyethyl Methacrylate Monomer in Chloroform for Selective Adsorption of Diazepam

MICHELLE FERDINAND (2024)

Diazepam is a benzodiazepine class usage is regulated nationally or globally. Monitoring the abuse of diazepam requires a sensitive analysis methods that required the preparation of selective methods. One of the methods that are currently develop

23-06-2024
Physicochemical Characteristics of Kaolin from Belitung Regency

NURUL I PASI (2024)

Kaolin is one of the abundant clay minerals on earth which has been widely used in various industries. kaolin as a raw material in drugs manufacturing must comply several requirements in Pharmacopoeia such as not exceeding the heavy metal content

23-06-2024
Gastroprotective Effect of Green Algae Extract (Ulva lactuca L) on Gastric Rats

WAHYU WIDYANINGSIH (2024)

Gastric ulcer is a disease of the digestive tract characterized by mucous damage to secretion of gastric acid and pepsin. One of the potential gastroprotector plants is green algae. The purpose of this study was to examine the gastroprotective ef

23-06-2024
Molecular Docking of Active Compounds Piper crocatum on The AlphaGlucosidase Enzyme as Antidiabetic

MUSTIKA WENI (2024)

Ethanol extract of Piper crocatum leaves has inhibitory activity of ?-glucosidase enzyme. Ethyl acetate fraction from Piper crocatum leaves has the highest antioxidant activity and has an inhibition of ?-glucosidase containing 6XO32ZSP1D, Ethyl L

23-06-2024
Inhibition of Heme Polymerization In Vitro Assay of Extract of Sirih Leaf (Piper Betle Linn.) and Sunflower Leaves (Helianthus Annuus L.)

AMI TJITRARESMI (2024)

Malaria is a disease that occurs in tropical countries like Indonesia. The incidence of malaria in the world is still quite high and the occurrence of cases of Plasmodium resistance to antimalarial drugs and the widespread of resistance have prom

23-06-2024
In Silico Study of Aglycon Curculigoside A and Its Derivatives as ? -Amilase Inhibitors

NURSAMSIAR (2024)

?-amilase is an enzyme that catalyzes the hydrolysis of starch polysaccharides into oligosaccharides to then produce glucose. Inhibitions of the ?-amylase enzyme is an effective strategy in modulating blood sugar levels in diabetes. The aglycon c

23-06-2024
Comparison Ability of Polymers Acrycoat S100 and HPMC K4M to Entrapment Efficiency Domperidone in Microspheres

PRATIWI APRIDAMAYANTI (2024)

Domperidone is a prokinetic and antiemetic agent which has low bioavaibility. To increase the bioavaibility of drug, it can be modified into microsphere that can hold drug more longer in gastric to improve the bioavaibility. The microsphere prepa

23-06-2024
Differences of Respiratory Rate between Salbutamol and Aminophylline in Exacerbation Asthma

AMELIA LORENSIA (2024)

Exacerbation of asthma is a progressive step in progressive breathing, coughing, wheezing, breathing. In Indonesia salbutamol nebulation is used for the therapy of the first exacerbation attack. The effectiveness of asthma exacerbation therapy ne

23-06-2024
Molecular Docking Studies of Compounds from Brucea javanica (L.) Merr. Towards the Discovery of Potential H5N1 Neuraminidase Inhibitors

RINA F NUWARDA (2024)

The occurrences of a highly pathogenic avian influenza virus (HPAI) type A H5N1 has caused infections in millions of poultry as well as hundreds of human cases and even mortalities. Indonesia has become one of the world’s highest casualty rates

26-08-2024
PENGARUH BAURAN PEMASARAN 7P (Marketing Mix) TERHADAP LOYALITAS PELANGGAN PADA SALAH SATU APOTEK DI KECAMATAN CICALENGKA KABUPATEN BANDUNG

SUSY WASILAH (2024)

Bauran Pemasaran 7P (Marketing Mix) merupakan salah satu strategi pemasaran yang memadukan atau mengombinasikan unsur-unsur pemasaran. Sedangkan loyalitas pelanggan adalah komitmen yang dipegang konsumen untuk selalu mengonsumsi kembali produk ata

03-07-2024
The 5th International Seminar on Pharmaceutical Sciences and Technology (ISPST) and The 3rd International Seminar on Expo of Jamu (ISEJ) Embedded in the 13th Annual Meeting (ISCC 2022)

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

FORMULATION AND EVALUATION OF SECANG (Caesalpinia sappan L.) WOOD EXTRACT LIP BALM WITH VARIOUS CONCENTRATION OF BEESWAX AND CANDELILLA WAX

03-07-2024
3 rd BANDUNG INTERNATIONAL TELECONFERENCE ON PHARMACY (3 rd BITP) 2023

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

LOZENGES FORMULATION OF CIPLUKAN FRUIT EXTRACT (Physalis angulata L.) WITH COMBINATION OF FILLER AGENTS AVICEL PH 102 - LUDIPRESS

03-07-2024
2 nd BANDUNG INTERNATIONAL TELECONFERENCE ON PHARMACY (2 nd BITP) 2022

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

FORMULATION AND EVALUATION OF THE ESSENTIAL OIL HAND CREAM PREPARATION OF BASIL LEAVES (Ocimum Basilicum) WITH VARIATION CONCENTRATION OF LIQUIDUM PARAFFIN AS AN EMOLLIENT

03-07-2024
1st BANDUNG INTERNATIONAL TELECONFERENCE ON PHARMACY (1st BITP) 2021

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

FORMULATION AND EVALUATION OF PEELOFF GEL FACIAL MASK FROM ARABICA COFFEE FRUIT PEEL EXTRACT (Coffea arabica L.)

03-07-2024
Factors Affecting the Synthesis of Bovine Serum Albumin Nanoparticles Using the Desolvation Method

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

: Currently, protein-based nanoparticles are in high demand as drug delivery systems due to their exceptional qualities, including nontoxicity, nonantigenicity, and biodegradability. Other qualities include high nutritional value, abundance of renew

03-07-2024
LOZENGES FORMULATION OF CIPLUKAN (PHYSALIS ANGULATA L.) FRUIT EXTRACT AS AN ANTIOXIDANT WITH COMBINATION OF FILLER AGENTS AVICEL PH 102–LUDIPRESS

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Objective: This research aimed to determine the effect of variations in the concentration of filler agents Avicel PH 102-Ludipress on the evaluation results of granules and tablets and to determine the antioxidant activity of ciplukan (Physalis angu

03-07-2024
IMPROVED SOLUBILITY OF CHOLECALCIFEROL AS BOVINE SERUM ALBUMIN (BSA) NANOPARTICLES

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Objective: This study aims to report the optimum formula for BSA nanoparticles cholecalciferol (BSA-NP cholecalciferol), which can increase the solubility of cholecalciferol. Methods: BSA cholecalciferol nanoparticles was prepared by desolvation me

03-07-2024
Formulation of Peel-off Gel Face Mask from Pandanus amaryllifolius (Roxb.) Leaves Extract

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

UV exposure is the most significant environmental risk factor that can be altered for skin cancer and many other skin conditions. An antioxidant is a compound that can protect the skin from sun radiation. Pandanus amaryllifolius is a plant that has

03-07-2024
Formulation of Hand Cream Essential Oil of Basil (Ocimum basilicum) Leaves

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Basil (Ocimum basilicum) leaf essential oil contains terpenoid compounds that have antibacterial activity. This study aims to obtain hand cream preparations of basil essential oil, as well as to determine the effect of concentration variation of li

03-07-2024
Formulation of Blush on Cream from Roselle (Hibiscus sabdariffa L.) Flower Extract with Olive Oil as Emollients

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Natural dyes have become more popular as a result of the harmful and carcinogenic effects of synthetic dyes. Anthocyanins are natural dyes that are widely used to replace synthetic dyes and can also act as antioxidants that can be found in rosella (H

03-07-2024
FORMULATION AND EVALUATION OF PEEL OFF GEL FACIAL MASK FROM ARABICA COFFEE FRUIT PEEL EXTRACT (COFFEA ARABICA L.)

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Objective: The aim of this study was to obtain a peel off gel facial mask preparation from Arabica coffee fruit peel extract that meets the requirements and to determine the antioxidant activity of Arabica coffee fruit peel extract and peel off gel

03-07-2024
Formulasi Dan Uji Stabilitas Fisik Sediaan Lip cream Ekstrak Ubi Jalar Ungu (Ipomoea batatas L.) Sebagai Pewarna Alami

Dr. apt. Yenni Puspita Tanjung, M.Farm. (2024)

Saat ini dipasaran masih terdapat kosmetik dekoratif yang menggunakan pewarna sintetik berbahaya. Sedangkan dalam kosmetik dekoratif warna merupakan bagian terpenting. Pigmen antosianin dalam ekstrak ubi jalar ungu (Ipomoea batatas L.) dapat digun

26-08-2022
Evaluasi Interaksi Obat Antihipertensi Pada Peresepan Pasien Penyakit Ginjal Kronik Unit Rawat Jalan Periode Juni - November 2021 di Salah Satu Rumah Sakit Swasta Kota Bandung

TIA NURAINI (2022)

Hipertensi merupakan salah satu faktor pemicu terjadinya penyakit ginjal kronik. Hal ini disebabkan oleh kerusakan pembuluh darah dalam ginjal sehingga terjadi penurunan kemampuan fungsi ginjal untuk memfiltrasi darah dengan baik. Penelitian ini b

26-08-2022
Evaluasi Ketersediaan Antibiotik di Salah Satu Apotek Kota Bandung

TITIN WARTINI (2022)

Ketersediaan obat yang baik di fasilitas kesehatan diperlukan untuk mendukung pelayanan kesehatan.Jika persediaan berlebih dapat meningkatkan biaya penyimpanan,obat kedaluarsa atau rusak,dan obat yang tidak ada pengeluaran (stok mati).Antibiotik m

26-08-2022
Formulasi dan Evaluasi Sediaan Spray Gel Ekstrak Pelepah Aren (Arenga pinnata Merr.) Sebagai Terapi Luka Terbuka

TRISNA SUNTARA (2022)

Ekstrak pelepah aren (Arenga pinnata Merr.) mengandung senyawa tanin yang dapat berfungsi sebagai obat luka terbuka. Salah satu inovasi sediaan yaitu dapat dibuat dalam bentuk spray gel. Spray gel merupakan salah satu bentuk pengembangan dari sedi

10-09-2022
Aktivitas Sedatif Infusa Daun Serai Wangi (Cymbopogon nardus (L.) Rendle) Pada Mencit jantan galur Swiss Webster

WAHYUNI MEGA HANDAYANI (2022)

Insomnia merupakan salah satu gangguan tidur dan gejala yang lebih parah dapat berpuncak pada timbulnya gangguan stres. Tingginya ancaman terdampak covid- 19 menimbulkan gangguan insomnia sehingga diperlukannya obat – obatan untuk mengatasi

10-09-2022
Uji Antioksidan Beberapa Jenis Madu Terlaris Pada Saat Pandemi Covid -19 (Corona Virus Disease 2019) Dengan Metode 2,2- Diphenyl-1-pycrilhydrazyl (DPPH)

YANTI LESTARI (2022)

Pada masa pandemi Covid-19 madu merupakan salah satu suplemen yang banyak dikonsumsi untuk meningkatkan imunitas tubuh. Madu berkhasiat bagi kesehatan karena mengandung mineral, protein, vitamin, asam organik, flavonoid, senyawa fenolik, enzim dan

10-09-2022
Pengujian Aktivitas Antioksidan Kopi Arabika (Coffea arabica) Gununghalu Teknik Light Roasting, Medium Roasting dan Dark Roasting Dengan Metode 2,2-diphenyl-1-pichrylhydrazyl (DPPH)

YENI PURNAMASARI (2022)

Kopi menjadi salah satu komoditas di dunia yang telah dibudidayakan oleh lebih dari 50 negara. Kopi arabika (cof ea arabica) adalah jenis kopi yang paling banyak diproduksi dan pangsa pasarnya di seluruh dunia yang mencapai 70%. Tanaman kopi merupa

10-09-2022
Uji Aktivitas Antibakteri Pada Gel Lidah Buaya Alami (Aloe Vera. L) dan Lidah Buaya Dalam Bentuk Sediaan Gel Yang Ada di Pasaran Terhadap Bakteri Propionibacterium Acnes Atcc 1223

YUTIKASARI (2022)

Lidah buaya merupakan tanaman fungsional karena dapat dapat dimanfaatkan untuk mengobati berbagai penyakit, termasuk penyakit kulit yang disebabkan oleh infeksi propionibacterium acnes penyebab jerawat. Karena lidah buaya mengandung senyawa berupa

10-09-2022
Evaluasi Kejadian Efek Samping Pengobatan Covid 19 Pada Pasien Isolasi Mandiri Tenaga Kesehatan Di Salah Satu Rumah Sakit Kota Bandung

ALDY ANDHIKA SETIAWAN (2022)

Tatalaksana pengobatan COVID-19 derajat ringan dengan Isolasi Mandiri dan Terapi Farmakologis diantaranya menggunakan antivirus, antioksidan, antibiotik serta antipiretik. Penelitian ini bertujuan untuk mengetahui karakteristik, efek samping yang

10-09-2022
Formulasi dan Evaluasi Sediaan Spray Gel Anti Nyamuk dari Minyak Atsiri Bunga Lavender (Lavandula angustifolia) dengan Variasi Konsentrasi HPMC (Hidroxy Propyl Methyl Cellulose) Sebagai Gelling Agent

AGUSTINA HERMAWATI (2022)

Minyak atsiri bunga lavender (Lavandula angustifolia) memiliki senyawa terpenoid yang berfungsi sebagai repellent sehingga dapat digunakan sebagai anti nyamuk. Penggunaan minyak atsiri langsung pada kulit dinilai kurang praktis sehingga perlu difo

10-09-2022
Pengaruh Suhu, Lama Penyimpanan, dan Jenis Kemasan Terhadap Kadar Vitamin C Dalam Minuman Kemasan dengan Menggunakan Metode Spektrofotometri UV

AGNES MONICA WIJAYA (2022)

Kebutuhan masyarakat akan vitamin C bertambah tinggi semenjak 2019 karena adanya Corona Virus Disease (Covid-19). Vitamin C memiliki keterbatasan dalam penyimpanan karena bersifat mudah teroksidasi oleh suhu dan lama penyimpanan. Penelitian ini be

10-09-2022
Uji Aktivitas Anti Bakteri Ekstrak Siwak (Salvadora persica) Terhadap Pertumbuhan Bakteri Streptococcus mutans Penyebab Karies Gigi

ADE ANDRI DIPRAJA (2022)

Saat ini banyak orang yang peduli dengan kesehatan beralih dari obat kimia ke jamu. Ada banyak tanaman herbal yang digunakan untuk kesehatan. Salah satunya adalah siwak (Salvadora persica) yang banyak manfaatnya untuk kesehatan umum dan kesehatan